GT-00AxIL15, a Novel Tumor-Targeted IL-15-Based Immunocytokine for the Treatment of TA-MUC1-Positive Solid Tumors: Preclinical In Vitro and In Vivo Pharmacodynamics and Biodistribution Studies
Gellert, Johanna, Jäkel, Anika, Danielczyk, Antje, Goletz, Christoph, Lischke, Timo, Flechner, Anke, Dix, Laura, Günzl, Alexandra, Kehler, Patrik
Published in International journal of molecular sciences (01.02.2024)
Published in International journal of molecular sciences (01.02.2024)
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Journal Article
CD38 Controls the Innate Immune Response against Listeria monocytogenes
Lischke, Timo, Heesch, Kira, Schumacher, Valéa, Schneider, Michael, Haag, Friedrich, Koch-Nolte, Friedrich, Mittrücker, Hans-Willi
Published in Infection and Immunity (01.11.2013)
Published in Infection and Immunity (01.11.2013)
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Identification of a super-functional Tfh-like subpopulation in murine lupus by pattern perception
Gryzik, Stefanie, Hoang, Yen, Lischke, Timo, Mohr, Elodie, Venzke, Melanie, Kadner, Isabelle, Poetzsch, Josephine, Groth, Detlef, Radbruch, Andreas, Hutloff, Andreas, Baumgrass, Ria
Published in eLife (22.05.2020)
Published in eLife (22.05.2020)
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Journal Article
CD38 is expressed on inflammatory cells of the intestine and promotes intestinal inflammation
Schneider, Michael, Schumacher, Valéa, Lischke, Timo, Lücke, Karsten, Meyer-Schwesinger, Catherine, Velden, Joachim, Koch-Nolte, Friedrich, Mittrücker, Hans-Willi
Published in PloS one (04.05.2015)
Published in PloS one (04.05.2015)
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Journal Article
Glyco-Engineered Anti-Human Programmed Death-Ligand 1 Antibody Mediates Stronger CD8 T Cell Activation Than Its Normal Glycosylated and Non-Glycosylated Counterparts
Goletz, Christoph, Lischke, Timo, Harnack, Ulf, Schiele, Phillip, Danielczyk, Antje, Rühmann, Johanna, Goletz, Steffen
Published in Frontiers in immunology (16.07.2018)
Published in Frontiers in immunology (16.07.2018)
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Journal Article
Adequate immune response ensured by binary IL-2 and graded CD25 expression in a murine transfer model
Fuhrmann, Franziska, Lischke, Timo, Gross, Fridolin, Scheel, Tobias, Bauer, Laura, Kalim, Khalid Wasim, Radbruch, Andreas, Herzel, Hanspeter, Hutloff, Andreas, Baumgrass, Ria
Published in eLife (30.12.2016)
Published in eLife (30.12.2016)
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Journal Article
Myeloid cells contribute indirectly to VEGF expression upon hypoxia via activation of Müller cells
Nürnberg, Christina, Kociok, Norbert, Brockmann, Claudia, Lischke, Timo, Crespo-Garcia, Sergio, Reichhart, Nadine, Wolf, Susanne, Baumgrass, Ria, Eming, Sabine A., Beer-Hammer, Sandra, Joussen, Antonia M.
Published in Experimental eye research (01.01.2018)
Published in Experimental eye research (01.01.2018)
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Journal Article
712 Preclinical characterization of GT-00A x IL15: A novel IL-15-based immunocytokine with unique tumor targeting properties
Jaekel, Anika, Kehler, Patrik, Lischke, Timo, Goletz, Christoph, Flechner, Anke, Danielczyk, Antje, Gellert, Johanna
Published in Journal for immunotherapy of cancer (01.11.2021)
Published in Journal for immunotherapy of cancer (01.11.2021)
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Journal Article
1462 Antibodies specifically recognizing cancer-associated glycoforms of mucin-like proteins
Neumann, Theresa, Hartung, Evelyn, Lischke, Timo, Kast, Naomi, Weiss, Lisa, Willmann, Luisa, Gurka, Stephanie, Marinoff, Sophie, Gellert, Johanna, Barke, Sven, Danielczyk, Antje, Kehler, Patrik
Published in Journal for immunotherapy of cancer (01.11.2023)
Published in Journal for immunotherapy of cancer (01.11.2023)
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Journal Article
CD4+ T-cell help is required for effective CD8+ T cell-mediated resolution of acute viral hepatitis in mice
Trautmann, Tanja, Kozik, Jan-Hendrik, Carambia, Antonella, Richter, Kirsten, Lischke, Timo, Schwinge, Dorothee, Mittrücker, Hans-Willi, Lohse, Ansgar W, Oxenius, Annette, Wiegard, Christiane, Herkel, Johannes
Published in PloS one (21.01.2014)
Published in PloS one (21.01.2014)
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Journal Article
Dataset on the activation of Müller cells through macrophages upon hypoxia in the retina
Nürnberg, Christina, Kociok, Norbert, Brockmann, Claudia, Lischke, Timo, Crespo-Garcia, Sergio, Reichhart, Nadine, Wolf, Susanne, Baumgrass, Ria, Eming, Sabine A., Beer-Hammer, Sandra, Joussen, Antonia M.
Published in Data in brief (01.02.2018)
Published in Data in brief (01.02.2018)
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Journal Article
Bin‐based visualization of cytokine‐co‐expression patterns of IL‐10‐producing CD4 T cell subsets
Mohr, Elodie, Hinnenthal, Timo, Gryzik, Stefanie, Hoang, Yen, Lischke, Timo, Retzlaff, Jimmy, Mekonnen, Ariana, Paul, Friedemann, Valleriani, Angelo, Radbruch, Andreas, Vera, Julio, Baumgrass, Ria
Published in European journal of immunology (01.10.2022)
Published in European journal of immunology (01.10.2022)
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Journal Article
ICOS Controls the Pool Size of Effector-Memory and Regulatory T Cells
Burmeister, Yvonne, Lischke, Timo, Dahler, Anja C, Mages, Hans Werner, Lam, Kong-Peng, Coyle, Anthony J, Kroczek, Richard A, Hutloff, Andreas
Published in The Journal of immunology (1950) (15.01.2008)
Published in The Journal of immunology (1950) (15.01.2008)
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Abstract 1588: Using glyco-engineered cells with flexible expression of tumor-associated carbohydrates for the generation of highly tumor-specific antibodies
Kehler, Patrik, Kast, Naomi, Weiske, Manon, Gurka, Stephanie, Lischke, Timo, Gellert, Johanna, Danielczyk, Antje
Published in Cancer research (Chicago, Ill.) (04.04.2023)
Published in Cancer research (Chicago, Ill.) (04.04.2023)
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Journal Article
Deubiquitinating Enzyme UCH-L1 Promotes Dendritic Cell Antigen Cross-Presentation by Favoring Recycling of MHC Class I Molecules
Reinicke, Anna T, Raczkowski, Friederike, Mühlig, Malte, Schmucker, Pina, Lischke, Timo, Reichelt, Julia, Schneider, Enja, Zielinski, Stephanie, Sachs, Marlies, Jurack, Elisabeth, Tolosa, Eva, Kurts, Christian, Mittrücker, Hans-Willi, Meyer-Schwesinger, Catherine
Published in The Journal of immunology (1950) (01.10.2019)
Published in The Journal of immunology (1950) (01.10.2019)
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Journal Article
Abstract 2879: Preclinical characterization of GT-00A x IL15: A novel IL-15-based immunocytokine with unique tumor targeting properties
Kehler, Patrik, Jaekel, Anika, Gellert, Johanna, Goletz, Christoph, Lischke, Timo, Flechner, Anke, Danielczyk, Antje, Neumann, Theresa
Published in Cancer research (Chicago, Ill.) (15.06.2022)
Published in Cancer research (Chicago, Ill.) (15.06.2022)
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Abstract 5896: Platform approach to develop antibodies specifically recognizing cancer-associated glycoforms
Kehler, Patrik, Gellert, Johanna, Kalfhues, Lisa, Marinoff, Sophie, Weis, Manon, Franz, Andreas, Kast, Naomi, Gurka, Stephanie, Morche, Marianne, Hartung, Evelyn, Lischke, Timo, Mayer-Hain, Sarah, Danielczyk, Antje
Published in Cancer research (Chicago, Ill.) (22.03.2024)
Published in Cancer research (Chicago, Ill.) (22.03.2024)
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Journal Article
1346 Antibodies against GlycoTargets as novel platform approach to address unmet needs in cancer therapy
Kehler, Patrik, Neumann, Theresa, Jaekel, Anika, Weis, Manon, Gellert, Johanna, Danielczyk, Antje, Hartung, Evelyn, Lischke, Timo, Gurka, Stephanie, Kast, Naomi, Weiske, Manon
Published in Journal for immunotherapy of cancer (01.11.2022)
Published in Journal for immunotherapy of cancer (01.11.2022)
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Journal Article
CD8‐β ADP‐ribosylation affects CD8+ T‐cell function
Lischke, Timo, Schumacher, Valéa, Wesolowski, Janusz, Hurwitz, Robert, Haag, Friedrich, Koch‐Nolte, Friedrich, Mittrücker, Hans‐Willi
Published in European journal of immunology (01.07.2013)
Published in European journal of immunology (01.07.2013)
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Nuclear Factor of Activated T Cells Regulates the Expression of Interleukin-4 in Th2 Cells in an All-or-none Fashion
Köck, Juliana, Kreher, Stephan, Lehmann, Katrin, Riedel, René, Bardua, Markus, Lischke, Timo, Jargosch, Manja, Haftmann, Claudia, Bendfeldt, Hanna, Hatam, Farahnaz, Mashreghi, Mir-Farzin, Baumgrass, Ria, Radbruch, Andreas, Chang, Hyun-Dong
Published in The Journal of biological chemistry (26.09.2014)
Published in The Journal of biological chemistry (26.09.2014)
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