The Novel Anticytomegalovirus Compound AIC246 (Letermovir) Inhibits Human Cytomegalovirus Replication through a Specific Antiviral Mechanism That Involves the Viral Terminase
GOLDNER, Thomas, HEWLETT, Guy, ETTISCHER, Nicole, RUEBSAMEN-SCHAEFF, Helga, ZIMMERMANN, Holger, LISCHKA, Peter
Published in Journal of Virology (01.10.2011)
Published in Journal of Virology (01.10.2011)
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Definitions of Resistant and Refractory Cytomegalovirus Infection and Disease in Transplant Recipients for Use in Clinical Trials
Chemaly, Roy F, Chou, Sunwen, Einsele, Hermann, Griffiths, Paul, Avery, Robin, Razonable, Raymund R, Mullane, Kathleen M, Kotton, Camille, Lundgren, Jens, Komatsu, Takashi E, Lischka, Peter, Josephson, Filip, Douglas, Cameron M, Umeh, Obi, Miller, Veronica, Ljungman, Per
Published in Clinical infectious diseases (08.04.2019)
Published in Clinical infectious diseases (08.04.2019)
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Geno- and Phenotypic Characterization of Human Cytomegalovirus Mutants Selected In Vitro after Letermovir (AIC246) Exposure
GOLDNER, Thomas, HEMPEL, Christine, RUEBSAMEN-SCHAEFF, Helga, ZIMMERMANN, Holger, LISCHKA, Peter
Published in Antimicrobial Agents and Chemotherapy (01.01.2014)
Published in Antimicrobial Agents and Chemotherapy (01.01.2014)
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In Vitro and In Vivo Activities of the Novel Anticytomegalovirus Compound AIC246
Lischka, Peter, Hewlett, Guy, Wunberg, Tobias, Baumeister, Judith, Paulsen, Daniela, Goldner, Thomas, Ruebsamen-Schaeff, Helga, Zimmermann, Holger
Published in Antimicrobial Agents and Chemotherapy (01.03.2010)
Published in Antimicrobial Agents and Chemotherapy (01.03.2010)
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Mutual Interplay between the Human Cytomegalovirus Terminase Subunits pUL51, pUL56, and pUL89 Promotes Terminase Complex Formation
Neuber, Sebastian, Wagner, Karen, Goldner, Thomas, Lischka, Peter, Steinbrueck, Lars, Messerle, Martin, Borst, Eva Maria
Published in Journal of virology (15.06.2017)
Published in Journal of virology (15.06.2017)
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In Vitro Evaluation of the Activities of the Novel Anticytomegalovirus Compound AIC246 (Letermovir) against Herpesviruses and Other Human Pathogenic Viruses
MARSCHALL, Manfred, STAMMINGER, Thomas, URBAN, Andreas, WILDUM, Steffen, RUEBSAMEN-SCHAEFF, Helga, ZIMMERMANN, Holger, LISCHKA, Peter
Published in Antimicrobial Agents and Chemotherapy (01.02.2012)
Published in Antimicrobial Agents and Chemotherapy (01.02.2012)
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Exploring the Human Cytomegalovirus Core Nuclear Egress Complex as a Novel Antiviral Target: A New Type of Small Molecule Inhibitors
Alkhashrom, Sewar, Kicuntod, Jintawee, Häge, Sigrun, Schweininger, Johannes, Muller, Yves A, Lischka, Peter, Marschall, Manfred, Eichler, Jutta
Published in Viruses (12.03.2021)
Published in Viruses (12.03.2021)
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Targeted mutagenesis on PDGFRα-Fc identifies amino acid modifications that allow efficient inhibition of HCMV infection while abolishing PDGF sequestration
Feldmann, Svenja, Grimm, Immanuel, Stöhr, Dagmar, Antonini, Chiara, Lischka, Peter, Sinzger, Christian, Stegmann, Cora
Published in PLoS pathogens (01.03.2021)
Published in PLoS pathogens (01.03.2021)
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Properties of Oligomeric Interaction of the Cytomegalovirus Core Nuclear Egress Complex (NEC) and Its Sensitivity to an NEC Inhibitory Small Molecule
Kicuntod, Jintawee, Alkhashrom, Sewar, Häge, Sigrun, Diewald, Benedikt, Müller, Regina, Hahn, Friedrich, Lischka, Peter, Sticht, Heinrich, Eichler, Jutta, Marschall, Manfred
Published in Viruses (11.03.2021)
Published in Viruses (11.03.2021)
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The cellular DExD/H-box RNA-helicases UAP56 and URH49 exhibit a CRM1-independent nucleocytoplasmic shuttling activity
Thomas, Marco, Lischka, Peter, Müller, Regina, Stamminger, Thomas
Published in PloS one (22.07.2011)
Published in PloS one (22.07.2011)
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Cellular p32 Recruits Cytomegalovirus Kinase pUL97 to Redistribute the Nuclear Lamina
Marschall, Manfred, Marzi, Andrea, Siepen, Patricia aus dem, Jochmann, Ramona, Kalmer, Martina, Auerochs, Sabrina, Lischka, Peter, Leis, Martina, Stamminger, Thomas
Published in The Journal of biological chemistry (30.09.2005)
Published in The Journal of biological chemistry (30.09.2005)
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The UL69 Transactivator Protein of Human Cytomegalovirus Interacts with DEXD/H-Box RNA Helicase UAP56 To Promote Cytoplasmic Accumulation of Unspliced RNA
Lischka, Peter, Toth, Zsolt, Thomas, Marco, Mueller, Regina, Stamminger, Thomas
Published in Molecular and Cellular Biology (01.03.2006)
Published in Molecular and Cellular Biology (01.03.2006)
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Inhibition of Human Cytomegalovirus Replication via Peptide Aptamers Directed against the Nonconventional Nuclear Localization Signal of the Essential Viral Replication Factor pUL84
KAISER, Nina, LISCHKA, Peter, WAGENKNECHT, Nadine, STAMMINGER, Thomas
Published in Journal of Virology (15.11.2009)
Published in Journal of Virology (15.11.2009)
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Sox10 Is an Active Nucleocytoplasmic Shuttle Protein, and Shuttling Is Crucial for Sox10-Mediated Transactivation
Rehberg, Stephan, Lischka, Peter, Glaser, Gabi, Stamminger, Thomas, Wegner, Michael, Rosorius, Olaf
Published in Molecular and Cellular Biology (01.08.2002)
Published in Molecular and Cellular Biology (01.08.2002)
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A Nonconventional Nuclear Localization Signal within the UL84 Protein of Human Cytomegalovirus Mediates Nuclear Import via the Importin α/β Pathway
Lischka, Peter, Sorg, Gabriele, Kann, Michael, Winkler, Michael, Stamminger, Thomas
Published in Journal of Virology (01.03.2003)
Published in Journal of Virology (01.03.2003)
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In vitro drug combination studies of Letermovir (AIC246, MK-8228) with approved anti-human cytomegalovirus (HCMV) and anti-HIV compounds in inhibition of HCMV and HIV replication
Wildum, Steffen, Zimmermann, Holger, Lischka, Peter
Published in Antimicrobial agents and chemotherapy (01.06.2015)
Published in Antimicrobial agents and chemotherapy (01.06.2015)
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