Selective stalling of human translation through small-molecule engagement of the ribosome nascent chain
Lintner, Nathanael G, McClure, Kim F, Petersen, Donna, Londregan, Allyn T, Piotrowski, David W, Wei, Liuqing, Xiao, Jun, Bolt, Michael, Loria, Paula M, Maguire, Bruce, Geoghegan, Kieran F, Huang, Austin, Rolph, Tim, Liras, Spiros, Doudna, Jennifer A, Dullea, Robert G, Cate, Jamie H D
Published in PLoS biology (21.03.2017)
Published in PLoS biology (21.03.2017)
Get full text
Journal Article
Receptor-Mediated Delivery of CRISPR-Cas9 Endonuclease for Cell-Type-Specific Gene Editing
Rouet, Romain, Thuma, Benjamin A, Roy, Marc D, Lintner, Nathanael G, Rubitski, David M, Finley, James E, Wisniewska, Hanna M, Mendonsa, Rima, Hirsh, Ariana, de Oñate, Lorena, Compte Barrón, Joan, McLellan, Thomas J, Bellenger, Justin, Feng, Xidong, Varghese, Alison, Chrunyk, Boris A, Borzilleri, Kris, Hesp, Kevin D, Zhou, Kaihong, Ma, Nannan, Tu, Meihua, Dullea, Robert, McClure, Kim F, Wilson, Ross C, Liras, Spiros, Mascitti, Vincent, Doudna, Jennifer A
Published in Journal of the American Chemical Society (30.05.2018)
Published in Journal of the American Chemical Society (30.05.2018)
Get full text
Journal Article
Structural and Functional Characterization of an Archaeal Clustered Regularly Interspaced Short Palindromic Repeat (CRISPR)-associated Complex for Antiviral Defense (CASCADE)
Lintner, Nathanael G., Kerou, Melina, Brumfield, Susan K., Graham, Shirley, Liu, Huanting, Naismith, James H., Sdano, Matthew, Peng, Nan, She, Qunxin, Copié, Valérie, Young, Mark J., White, Malcolm F., Lawrence, C. Martin
Published in The Journal of biological chemistry (17.06.2011)
Published in The Journal of biological chemistry (17.06.2011)
Get full text
Journal Article
Cyclic Tetra-Adenylate (cA 4 ) Recognition by Csa3; Implications for an Integrated Class 1 CRISPR-Cas Immune Response in Saccharolobus solfataricus
Charbonneau, Alexander A, Eckert, Debra M, Gauvin, Colin C, Lintner, Nathanael G, Lawrence, C Martin
Published in Biomolecules (Basel, Switzerland) (09.12.2021)
Published in Biomolecules (Basel, Switzerland) (09.12.2021)
Get full text
Journal Article
Correction: Selective stalling of human translation through small-molecule engagement of the ribosome nascent chain
Lintner, Nathanael G, McClure, Kim F, Petersen, Donna, Londregan, Allyn T, Piotrowski, David W, Wei, Liuqing, Xiao, Jun, Bolt, Michael, Loria, Paula M, Maguire, Bruce, Geoghegan, Kieran F, Huang, Austin, Rolph, Tim, Liras, Spiros, Doudna, Jennifer A, Dullea, Robert G, Cate, Jamie H D
Published in PLoS biology (01.04.2018)
Published in PLoS biology (01.04.2018)
Get full text
Journal Article
Small Molecule Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Inhibitors: Hit to Lead Optimization of Systemic Agents
Londregan, Allyn T, Wei, Liuqing, Xiao, Jun, Lintner, Nathanael G, Petersen, Donna, Dullea, Robert G, McClure, Kim F, Bolt, Michael W, Warmus, Joseph S, Coffey, Steven B, Limberakis, Chris, Genovino, Julien, Thuma, Benjamin A, Hesp, Kevin D, Aspnes, Gary E, Reidich, Benjamin, Salatto, Christopher T, Chabot, Jeffrey R, Cate, Jamie H. D, Liras, Spiros, Piotrowski, David W
Published in Journal of medicinal chemistry (12.07.2018)
Published in Journal of medicinal chemistry (12.07.2018)
Get full text
Journal Article
Structural studies of Acidianus tailed spindle virus reveal a structural paradigm used in the assembly of spindle-shaped viruses
Hochstein, Rebecca, Bollschweiler, Daniel, Dharmavaram, Sanjay, Lintner, Nathanael G., Plitzko, Jürgen M., Bruinsma, Robijn, Engelhardt, Harald, Young, Mark J., Klug, William S., Lawrence, C. Martin
Published in Proceedings of the National Academy of Sciences - PNAS (27.02.2018)
Published in Proceedings of the National Academy of Sciences - PNAS (27.02.2018)
Get full text
Journal Article
The Structure of the CRISPR-Associated Protein Csa3 Provides Insight into the Regulation of the CRISPR/Cas System
Lintner, Nathanael G., Frankel, Kenneth A., Tsutakawa, Susan E., Alsbury, Donald L., Copié, Valérie, Young, Mark J., Tainer, John A., Lawrence, C. Martin
Published in Journal of molecular biology (28.01.2011)
Published in Journal of molecular biology (28.01.2011)
Get full text
Journal Article
Sickle Cell Disease Model Mice Lacking 2,3-Dpg Show Reduced RBC Sickling and Improvements in Markers of Hemolytic Anemia
Knee, Kelly M., Barakat, Amey, Tomlinson, Lindsay, Ramaiah, Lila, Wenzel, Zane, Kapinos, Brendon, Ahn, Youngwook, Lintner, Nathanael G., Field, S. Denise, Jasuja, Reema, Pettersen, Betty A.
Published in Blood (05.11.2020)
Published in Blood (05.11.2020)
Get full text
Journal Article