Identification of ADAMTS7 as a novel locus for coronary atherosclerosis and association of ABO with myocardial infarction in the presence of coronary atherosclerosis: two genome-wide association studies
Reilly, Muredach P, Dr, Li, Mingyao, PhD, He, Jing, PhD, Ferguson, Jane F, PhD, Stylianou, Ioannis M, PhD, Mehta, Nehal N, MD, Burnett, Mary Susan, PhD, Devaney, Joseph M, PhD, Knouff, Christopher W, MD, Thompson, John R, Prof, Horne, Benjamin D, PhD, Stewart, Alexandre FR, PhD, Assimes, Themistocles L, MD, Wild, Philipp S, MD, Allayee, Hooman, PhD, Nitschke, Patrick Linsel, MD, Patel, Riyaz S, MD, Martinelli, Nicola, MD, Girelli, Domenico, Prof, Quyyumi, Arshed A, Prof, Anderson, Jeffrey L, Prof, Erdmann, Jeanette, Prof, Hall, Alistair S, MD, Schunkert, Heribert, Prof, Quertermous, Thomas, Prof, Blankenberg, Stefan, Prof, Hazen, Stanley L, Prof, Roberts, Robert, Prof, Kathiresan, Sekar, MD, Samani, Nilesh J, Prof, Epstein, Stephen E, Prof, Rader, Daniel J, Prof
Published in The Lancet (British edition) (29.01.2011)
Published in The Lancet (British edition) (29.01.2011)
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Genetic variation at chromosome 1p13.3 affects sortilin mRNA expression, cellular LDL-uptake and serum LDL levels which translates to the risk of coronary artery disease
Linsel-Nitschke, Patrick, Heeren, Jörg, Aherrahrou, Zouhair, Bruse, Petra, Gieger, Christian, Illig, Thomas, Prokisch, Holger, Heim, Katharina, Doering, Angela, Peters, Annette, Meitinger, Thomas, Wichmann, H.-Erich, Hinney, Anke, Reinehr, Thomas, Roth, Christian, Ortlepp, Jan. R, Soufi, Mouhidien, Sattler, Alexander M, Schaefer, Jürgen, Stark, Klaus, Hengstenberg, Christian, Schaefer, Arne, Schreiber, Stefan, Kronenberg, Florian, Samani, Nilesh J, Schunkert, Heribert, Erdmann, Jeanette
Published in Atherosclerosis (01.01.2010)
Published in Atherosclerosis (01.01.2010)
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Journal Article
ATP-binding cassette transporter A7 enhances phagocytosis of apoptotic cells and associated ERK signaling in macrophages
Jehle, Andreas W, Gardai, Shyra J, Li, Suzhao, Linsel-Nitschke, Patrick, Morimoto, Konosuke, Janssen, William J, Vandivier, R. William, Wang, Nan, Greenberg, Steven, Dale, Benjamin M, Qin, Chunbo, Henson, Peter M, Tall, Alan R
Published in The Journal of cell biology (14.08.2006)
Published in The Journal of cell biology (14.08.2006)
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ATP-binding Cassette Transporter A7 (ABCA7) Binds Apolipoprotein A-I and Mediates Cellular Phospholipid but Not Cholesterol Efflux
Wang, Nan, Lan, Debin, Gerbod-Giannone, Marie, Linsel-Nitschke, Patrick, Jehle, Andreas Werner, Chen, Wengen, Martinez, Laurent O., Tall, Alan R.
Published in The Journal of biological chemistry (31.10.2003)
Published in The Journal of biological chemistry (31.10.2003)
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An Alternative Splice Variant in Abcc6, the Gene Causing Dystrophic Calcification, Leads to Protein Deficiency in C3H/He Mice
Aherrahrou, Zouhair, Doehring, Lars C., Ehlers, Eva-Maria, Liptau, Henrike, Depping, Reinhard, Linsel-Nitschke, Patrick, Kaczmarek, Piotr M., Erdmann, Jeanette, Schunkert, Heribert
Published in The Journal of biological chemistry (21.03.2008)
Published in The Journal of biological chemistry (21.03.2008)
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Lack of Association Between a Common Polymorphism Near the INSIG2 Gene and BMI, Myocardial Infarction, and Cardiovascular Risk Factors
Wiedmann, Silke, Neureuther, Katharina, Stark, Klaus, Reinhard, Wibke, Kallmünzer, Bernd, Baessler, Andrea, Fischer, Marcus, Linsel‐Nitschke, Patrick, Erdmann, Jeanette, Schunkert, Heribert, Hengstenberg, Christian
Published in Obesity (Silver Spring, Md.) (01.07.2009)
Published in Obesity (Silver Spring, Md.) (01.07.2009)
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Journal Article
A PEST sequence in ABCA1 regulates degradation by calpain protease and stabilization of ABCA1 by apoA-I
Wang, Nan, Chen, Wengen, Linsel-Nitschke, Patrick, Martinez, Laurent O., Agerholm-Larsen, Birgit, Silver, David L., Tall, Alan R.
Published in The Journal of clinical investigation (01.01.2003)
Published in The Journal of clinical investigation (01.01.2003)
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Journal Article
Potential role of ABCA7 in cellular lipid efflux to apoA-I
Linsel-Nitschke, Patrick, Jehle, Andreas W., Shan, Jing, Cao, Guoqing, Bacic, Desa, Lan, Debin, Wang, Nan, Tall, Alan R.
Published in Journal of lipid research (01.01.2005)
Published in Journal of lipid research (01.01.2005)
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Macrophage cholesterol efflux correlates with lipoprotein subclass distribution and risk of obstructive coronary artery disease in patients undergoing coronary angiography
Linsel-Nitschke, Patrick, Jansen, Henning, Aherrarhou, Zouhair, Belz, Stefanie, Mayer, Björn, Lieb, Wolfgang, Huber, Fritz, Kremer, Werner, Kalbitzer, Hans-Robert, Erdmann, Jeanette, Schunkert, Heribert
Published in Lipids in health and disease (06.04.2009)
Published in Lipids in health and disease (06.04.2009)
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Expression and Role of Cubilin in the Internalization of Nutrients During the Peri-Implantation Development of the Rodent Embryo
Assémat, Emeline, Vinot, Stéphanie, Gofflot, Françoise, Linsel-Nitschke, Patrick, Illien, Françoise, Châtelet, François, Verroust, Pierre, Louvet-Vallée, Sophie, Rinninger, Franz, Kozyraki, Renata
Published in Biology of reproduction (01.05.2005)
Published in Biology of reproduction (01.05.2005)
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Journal Article
Expression and Role of Cubilin in the Internalization of Nutrients During the Peri-Implantation Development of the Rodent Embryo1
Assémat, Emeline, Vinot, Stéphanie, Gofflot, Françoise, Linsel-Nitschke, Patrick, Illien, Françoise, Châtelet, François, Verroust, Pierre, Louvet-Vallée, Sophie, Rinninger, Franz, Kozyraki, Renata
Published in Biology of reproduction (01.05.2005)
Published in Biology of reproduction (01.05.2005)
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Journal Article
Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants
Kathiresan, Sekar, Voight, Benjamin F, Purcell, Shaun, Musunuru, Kiran, Ardissino, Diego, Mannucci, Pier M, Anand, Sonia, Engert, James C, Samani, Nilesh J, Schunkert, Heribert, Erdmann, Jeanette, Reilly, Muredach P, Rader, Daniel J, Morgan, Thomas, Spertus, John A, Stoll, Monika, Girelli, Domenico, McKeown, Pascal P, Patterson, Chris C, Siscovick, David S, O'Donnell, Christopher J, Elosua, Roberto, Peltonen, Leena, Salomaa, Veikko, Schwartz, Stephen M, Melander, Olle, Altshuler, David, Merlini, Pier Angelica, Berzuini, Carlo, Bernardinelli, Luisa, Peyvandi, Flora, Tubaro, Marco, Celli, Patrizia, Ferrario, Maurizio, Fetiveau, Raffaela, Marziliano, Nicola, Casari, Giorgio, Galli, Michele, Ribichini, Flavio, Rossi, Marco, Bernardi, Francesco, Zonzin, Pietro, Piazza, Alberto, Yee, Jean, Friedlander, Yechiel, Marrugat, Jaume, Lucas, Gavin, Subirana, Isaac, Sala, Joan, Ramos, Rafael, Meigs, James B, Williams, Gordon, Nathan, David M, MacRae, Calum A, Havulinna, Aki S, Berglund, Goran, Hirschhorn, Joel N, Asselta, Rosanna, Duga, Stefano, Spreafico, Marta, Daly, Mark J, Nemesh, James, Korn, Joshua M, McCarroll, Steven A, Surti, Aarti, Guiducci, Candace, Gianniny, Lauren, Mirel, Daniel, Parkin, Melissa, Burtt, Noel, Gabriel, Stacey B, Thompson, John R, Braund, Peter S, Wright, Benjamin J, Balmforth, Anthony J, Ball, Stephen G, Hall, Alistair S
Published in Nature genetics (01.03.2009)
Published in Nature genetics (01.03.2009)
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Journal Article
New susceptibility locus for coronary artery disease on chromosome 3q22.3
Perret, Claire, Blankenberg, Stefan, Stark, Klaus, Braund, Peter S, Rubin, Diana, Deloukas, Panos, Ball, Stephen G, Schäfer, Arne, Thompson, John R, Voight, Benjamin F, Zeller, Tanja, Schunkert, Heribert, Ouwehand, Willem H, Merlini, Piera Angelica, Schrezenmeir, Jürgen, Linsel-Nitschke, Patrick, Bernardinelli, Luisa, Elosua, Roberto, Wright, Ben, Peyvandi, Flora, Schillert, Arne, Meisinger, Christa, Hengstenberg, Christian, Samani, Nilesh J, Salomaa, Veikko, Peltonen, Leena, Melander, Olle, Schreiber, Stefan, Trégouët, David-Alexandre, Mokhtari, Nour Eddine El, Schwarz, Daniel F, Balmforth, Anthony J, Kathiresan, Sekar, Wagner, Arnika K, Siscovick, David S, Schwartz, Stephen M, Bugert, Peter, Ardissino, Diego, König, Inke R, Aherrahrou, Zouhair, Wild, Philipp, Erdmann, Jeanette, Baumert, Jens, Renner, Wilfried, Bruse, Petra, Klüter, Harald, Altshuler, David, März, Winfried, Wichmann, H-Erich, Ziegler, Andreas, Fischer, Marcus, Hall, Alistair S, Cambien, Francois, Meitinger, Thomas, Großhennig, Anika, Tiret, Laurence, O'Donnell, Christopher J, Peters, Annette
Published in Nature genetics (01.03.2009)
Published in Nature genetics (01.03.2009)
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Genome-wide haplotype association study identifies the SLC22A3-LPAL2-LPA gene cluster as a risk locus for coronary artery disease
Germain, Cécile, Luc, Gérald, Großhennig, Anika, Ruidavets, Jean-Bernard, Preuss, Michael, Morrison, Caroline, Schreiber, Stefan, Stark, Klaus, van der Harst, Pim, Trégouët, David-Alexandre, Cambien, Francois, Munteanu, Alexandru, Thompson, John R, Neureuther, Katharina, Rubin, Diana, Perret, Claire, Tiret, Laurence, Ball, Stephen G, Schäfer, Arne, Meisinger, Christa, Hall, Alistair S, Bugert, Peter, Braund, Peter S, Schunkert, Heribert, Linsel-Nitschke, Patrick, Evans, Alun, Wichmann, H-Erich, Meitinger, Thomas, Wright, Ben J, König, Inke R, Schrezenmeir, Jürgen, Ouwehand, Willem, Erdmann, Jeanette, Arveiler, Dominique, El Mokhtari, Nour E, Ziegler, Andreas, Balmforth, Anthony J, Hengstenberg, Christian, DeSuremain, Maylis, Samani, Nilesh J
Published in Nature genetics (01.03.2009)
Published in Nature genetics (01.03.2009)
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A trans -acting locus regulates an anti-viral expression network and type 1 diabetes risk
Hubner, Norbert, Cook, Stuart A, Heinig, Matthias, Petretto, Enrico, Wallace, Chris, Bottolo, Leonardo, Rotival, Maxime, Lu, Han, Li, Yoyo, Sarwar, Rizwan, Langley, Sarah R, Bauerfeind, Anja, Hummel, Oliver, Lee, Young-Ae, Paskas, Svetlana, Rintisch, Carola, Saar, Kathrin, Cooper, Jason, Buchan, Rachel, Gray, Elizabeth E, Cyster, Jason G, Erdmann, Jeanette, Hengstenberg, Christian, Maouche, Seraya, Ouwehand, Willem H, Rice, Catherine M, Samani, Nilesh J, Schunkert, Heribert, Goodall, Alison H, Schulz, Herbert, Roider, Helge G, Vingron, Martin, Blankenberg, Stefan, Münzel, Thomas, Zeller, Tanja, Szymczak, Silke, Ziegler, Andreas, Tiret, Laurence, Smyth, Deborah J, Pravenec, Michal, Aitman, Timothy J, Cambien, Francois, Clayton, David, Todd, John A
Published in Nature (London) (23.09.2010)
Published in Nature (London) (23.09.2010)
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Repeated Replication and a Prospective Meta-Analysis of the Association Between Chromosome 9p21.3 and Coronary Artery Disease
SCHUNKERT, Heribert, GÖTZ, Anika, BLANKENBERG, Stefan, TIRET, Laurence, DUCIMETIERE, Pierre, KENIRY, Andrew, GHORI, Mohammed J. R, SCHREIBER, Stefan, EL MOKHTARI, Nour Eddine, HALL, Alistair S, DIXON, Richard J, GOODALL, Alison H, BRAUND, Peter, LIPTAU, Henrike, POLLARD, Helen, SCHWARZ, Daniel F, HOTHOM, Ludwig A, WICHMANN, H.-Erich, KÖNIG, Inke R, FISCHER, Marcus, MEISINGER, Christa, OUWEHAND, Willem, DELOUKAS, Panos, MCGINNIS, Ralph, THOMPSON, John R, ERDMANN, Jeanette, ZIEGLER, Andreas, SAMANI, Nilesh J, TREGOUET, David-Alexandre, MANGINO, Massimo, LINSEL-NITSCHKE, Patrick, CAMBIEN, Francois, HENGSTENBERG, Christian, STARK, Klaus
Published in Circulation (New York, N.Y.) (01.04.2008)
Published in Circulation (New York, N.Y.) (01.04.2008)
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Sorting Out Cholesterol and Coronary Artery Disease
Linsel-Nitschke, Patrick, Samani, Nilesh J, Schunkert, Heribert
Published in The New England journal of medicine (16.12.2010)
Published in The New England journal of medicine (16.12.2010)
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