p53 at the crossroad of DNA replication and ribosome biogenesis stress pathways
Lindström, Mikael S., Bartek, Jiri, Maya-Mendoza, Apolinar
Published in Cell death and differentiation (01.05.2022)
Published in Cell death and differentiation (01.05.2022)
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The antimalarial drug amodiaquine stabilizes p53 through ribosome biogenesis stress, independently of its autophagy-inhibitory activity
Espinoza, Jaime A., Zisi, Asimina, Kanellis, Dimitris C., Carreras-Puigvert, Jordi, Henriksson, Martin, Hühn, Daniela, Watanabe, Kenji, Helleday, Thomas, Lindström, Mikael S., Bartek, Jiri
Published in Cell death and differentiation (01.02.2020)
Published in Cell death and differentiation (01.02.2020)
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SFRP2 induces a mesenchymal subtype transition by suppression of SOX2 in glioblastoma
Guo, Min, Goudarzi, Kaveh M., Abedi, Shiva, Pieber, Melanie, Sjöberg, Elin, Behnan, Jinan, Zhang, Xing-Mei, Harris, Robert A., Bartek, Jiri, Lindström, Mikael S., Nistér, Monica, Hägerstrand, Daniel
Published in Oncogene (12.08.2021)
Published in Oncogene (12.08.2021)
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Loss of Nucleolar Histone Chaperone NPM1 Triggers Rearrangement of Heterochromatin and Synergizes with a Deficiency in DNA Methyltransferase DNMT3A to Drive Ribosomal DNA Transcription
Holmberg Olausson, Karl, Nistér, Monica, Lindström, Mikael S.
Published in The Journal of biological chemistry (12.12.2014)
Published in The Journal of biological chemistry (12.12.2014)
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Actionable cancer vulnerability due to translational arrest, p53 aggregation and ribosome biogenesis stress evoked by the disulfiram metabolite CuET
Kanellis, Dimitris C., Zisi, Asimina, Skrott, Zdenek, Lemmens, Bennie, Espinoza, Jaime A., Kosar, Martin, Björkman, Andrea, Li, Xuexin, Arampatzis, Stefanos, Bartkova, Jirina, Andújar-Sánchez, Miguel, Fernandez-Capetillo, Oscar, Mistrik, Martin, Lindström, Mikael S., Bartek, Jiri
Published in Cell death and differentiation (01.07.2023)
Published in Cell death and differentiation (01.07.2023)
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Small molecule-mediated disruption of ribosome biogenesis synergizes with FGFR inhibitors to suppress glioma cell growth
Zisi, Asimina, Kanellis, Dimitris C, Moussaud, Simon, Karlsson, Ida, Carén, Helena, Bräutigam, Lars, Bartek, Jiri, Lindström, Mikael S
Published in Neuro-oncology (Charlottesville, Va.) (02.06.2023)
Published in Neuro-oncology (Charlottesville, Va.) (02.06.2023)
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Thermal Proteome Profiling Identifies Oxidative-Dependent Inhibition of the Transcription of Major Oncogenes as a New Therapeutic Mechanism for Select Anticancer Compounds
Peuget, Sylvain, Zhu, Jiawei, Sanz, Gema, Singh, Madhurendra, Gaetani, Massimiliano, Chen, Xinsong, Shi, Yao, Saei, Amir Ata, Visnes, Torkild, Lindström, Mikael S, Rihani, Ali, Moyano-Galceran, Lidia, Carlson, Joseph W, Hjerpe, Elisabet, Joneborg, Ulrika, Lehti, Kaisa, Hartman, Johan, Helleday, Thomas, Zubarev, Roman, Selivanova, Galina
Published in Cancer research (Chicago, Ill.) (01.04.2020)
Published in Cancer research (Chicago, Ill.) (01.04.2020)
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Targeted Inactivation of Mdm2 RING Finger E3 Ubiquitin Ligase Activity in the Mouse Reveals Mechanistic Insights into p53 Regulation
Itahana, Koji, Mao, Hua, Jin, Aiwen, Itahana, Yoko, Clegg, Hilary V., Lindström, Mikael S., Bhat, Krishna P., Godfrey, Virginia L., Evan, Gerard I., Zhang, Yanping
Published in Cancer cell (01.10.2007)
Published in Cancer cell (01.10.2007)
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mTOR inhibitors blunt the p53 response to nucleolar stress by regulating RPL11 and MDM2 levels
Goudarzi, Kaveh M, Nistér, Monica, Lindström, Mikael S
Published in Cancer biology & therapy (01.01.2014)
Published in Cancer biology & therapy (01.01.2014)
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The exon-junction complex helicase eIF4A3 controls cell fate via coordinated regulation of ribosome biogenesis and translational output
Kanellis, Dimitris C, Espinoza, Jaime A, Zisi, Asimina, Sakkas, Elpidoforos, Bartkova, Jirina, Katsori, Anna-Maria, Boström, Johan, Dyrskjøt, Lars, Broholm, Helle, Altun, Mikael, Elsässer, Simon J, Lindström, Mikael S, Bartek, Jiri
Published in Science advances (01.08.2021)
Published in Science advances (01.08.2021)
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Brain abnormalities and glioma-like lesions in mice overexpressing the long isoform of PDGF-A in astrocytic cells
Nazarenko, Inga, Hedrén, Anna, Sjödin, Hanna, Orrego, Abiel, Andrae, Johanna, Afink, Gijs B, Nistér, Monica, Lindström, Mikael S
Published in PloS one (07.04.2011)
Published in PloS one (07.04.2011)
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DNA damage-induced dynamic changes in abundance and cytosol-nuclear translocation of proteins involved in translational processes, metabolism, and autophagy
Bennetzen, Martin V., Kosar, Martin, Bunkenborg, Jakob, Payne, Mark Ronald, Bartkova, Jirina, Lindström, Mikael S., Lukas, Jiri, Andersen, Jens S., Bartek, Jiri, Larsen, Dorthe Helena
Published in Cell cycle (Georgetown, Tex.) (01.01.2018)
Published in Cell cycle (Georgetown, Tex.) (01.01.2018)
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