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Degradation of Polycomb Repressive Complex 2 with an EED-Targeted Bivalent Chemical Degrader
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Published in Journal of medicinal chemistry (11.02.2021)
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A chemical probe targeting the PWWP domain alters NSD2 nucleolar localization
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Systematic Variation of Both the Aromatic Cage and Dialkyllysine via GCE-SAR Reveal Mechanistic Insights in CBX5 Reader Protein Binding
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Zhu, Zhichuan, Johnson, Rebecca L., Zhang, Zhigang, Herring, Laura E., Jiang, Guochun, Damania, Blossom, James, Lindsey I., Liu, Pengda
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Published in Cellular and molecular life sciences : CMLS (01.06.2023)
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Jefferys, Stuart R, Burgos, Samuel D, Peterson, Jackson J, Selitsky, Sara R, Turner, Anne-Marie W, James, Lindsey I, Tsai, Yi-Hsuan, Coffey, Alisha R, Margolis, David M, Parker, Joel, Browne, Edward P
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Published in PloS one (09.10.2012)
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Engelberg, Isabelle A, Liu, Jiuyang, Norris-Drouin, Jacqueline L, Cholensky, Stephanie H, Ottavi, Samantha A, Frye, Stephen V, Kutateladze, Tatiana G, James, Lindsey I
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An Orally Bioavailable Chemical Probe of the Lysine Methyltransferases EZH2 and EZH1
Konze, Kyle D, Ma, Anqi, Li, Fengling, Barsyte-Lovejoy, Dalia, Parton, Trevor, MacNevin, Christopher J, Liu, Feng, Gao, Cen, Huang, Xi-Ping, Kuznetsova, Ekaterina, Rougie, Marie, Jiang, Alice, Pattenden, Samantha G, Norris, Jacqueline L, James, Lindsey I, Roth, Bryan L, Brown, Peter J, Frye, Stephen V, Arrowsmith, Cheryl H, Hahn, Klaus M, Wang, Gang Greg, Vedadi, Masoud, Jin, Jian
Published in ACS chemical biology (21.06.2013)
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Structural Basis for the Binding Selectivity of Human CDY Chromodomains
Dong, Cheng, Liu, Yanli, Lyu, Tian-Jie, Beldar, Serap, Lamb, Kelsey N., Tempel, Wolfram, Li, Yanjun, Li, Zoey, James, Lindsey I., Qin, Su, Wang, Yun, Min, Jinrong
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Published in Cell chemical biology (16.07.2020)
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Barnash, Kimberly D, James, Lindsey I, Frye, Stephen V
Published in Nature chemical biology (01.10.2017)
Published in Nature chemical biology (01.10.2017)
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Suh, Junghyun L., Bsteh, Daniel, Hart, Bryce, Si, Yibo, Weaver, Tyler M., Pribitzer, Carina, Lau, Roy, Soni, Shivani, Ogana, Heather, Rectenwald, Justin M., Norris, Jacqueline L., Cholensky, Stephanie H., Sagum, Cari, Umana, Jessica D., Li, Dongxu, Hardy, Brian, Bedford, Mark T., Mumenthaler, Shannon M., Lenz, Heinz-Josef, Kim, Yong-Mi, Wang, Gang Greg, Pearce, Ken H., James, Lindsey I., Kireev, Dmitri B., Musselman, Catherine A., Frye, Stephen V., Bell, Oliver
Published in Cell chemical biology (21.04.2022)
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A cellular chemical probe targeting the chromodomains of Polycomb repressive complex 1
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Published in Nature chemical biology (01.03.2016)
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Hanley, Ronan P., Nie, David Y., Tabor, John R., Li, Fengling, Sobh, Amin, Xu, Chenxi, Barker, Natalie K., Dilworth, David, Hajian, Taraneh, Gibson, Elisa, Szewczyk, Magdalena M., Brown, Peter J., Barsyte-Lovejoy, Dalia, Herring, Laura E., Wang, Gang Greg, Licht, Jonathan D., Vedadi, Masoud, Arrowsmith, Cheryl H., James, Lindsey I.
Published in Journal of the American Chemical Society (12.04.2023)
Published in Journal of the American Chemical Society (12.04.2023)
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