Potent in vitro and in vivo inhibitors of platelet aggregation based upon the Arg-Gly-Asp-Phe sequence of fibrinogen. A proposal on the nature of the binding interaction between the Arg-guanidine of RGDX mimetics and the platelet GP IIb-IIIa receptor
Zablocki, Jeffery A, Miyano, Masateru, Garland, Robert B, Pireh, Daisy, Schretzman, Lori, Rao, Shashidhar N, Lindmark, Richard J, Panzer-Knodle, Susan G, Nicholson, Nancy S
Published in Journal of medicinal chemistry (01.06.1993)
Published in Journal of medicinal chemistry (01.06.1993)
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A highly stereoselective Michael addition to an .alpha.,.beta.-unsaturated ester as the crucial step in the synthesis of a novel .beta.-amino acid-containing fibrinogen receptor antagonist
Rico, Joseph G, Lindmark, Richard J, Rogers, Thomas E, Bovy, Philippe R
Published in Journal of organic chemistry (01.12.1993)
Published in Journal of organic chemistry (01.12.1993)
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Multi-step polymer-assisted solution-phase (PASP) library synthesis of functionalized diaminobenzamides
South, M S, Case, B L, Dice, T A, Franklin, G W, Hayes, M J, Jones, D E, Lindmark, R J, Zeng, Q, Parlow, J J
Published in Combinatorial chemistry & high throughput screening (01.04.2000)
Published in Combinatorial chemistry & high throughput screening (01.04.2000)
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Potent in Vitro and in Vivo Inhibitors of Platelet Aggregation Based Upon the Arg-Gly-Asp Sequence of Fibrinogen. (Aminobenzamidino)succinyl (ABAS) Series of Orally Active Fibrinogen Receptor Antagonists
Zablocki, Jeffery A, Rico, Joseph G, Garland, Robert B, Rogers, Thomas E, Williams, Kenneth, Schretzman, Lori A, Rao, Shashidhar A, Bovy, Philippe R, Tjoeng, Foe S
Published in Journal of medicinal chemistry (01.06.1995)
Published in Journal of medicinal chemistry (01.06.1995)
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A novel series of orally active antiplatelet agents
Zablocki, Jeffery A., Tjoeng, Foe S., Bovy, Philippe R., Miyano, Masateru, Garland, Robert B., Williams, Kenneth, Schretzman, Lori, Zupec, Mark E., Rico, Joseph G., Lindmark, Richard J., Toth, Mihaly V., McMackins, Dudley E., Adams, Steven P., Panzer-Knodle, Susan G., Nicholson, Nancy S., Taite, Beatrice B., Salyers, Anita K., King, Lucy W., Campion, James G., Feigen, Larry P.
Published in Bioorganic & medicinal chemistry (01.05.1995)
Published in Bioorganic & medicinal chemistry (01.05.1995)
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