Interferon inducible X-linked gene CXorf21 may contribute to sexual dimorphism in Systemic Lupus Erythematosus
Odhams, Christopher A, Roberts, Amy L, Vester, Susan K, Duarte, Carolina S T, Beales, Charlie T, Clarke, Alexander J, Lindinger, Sonja, Daffern, Samuel J, Zito, Antonino, Chen, Lingyan, Jones, Leonardo L, Boteva, Lora, Morris, David L, Small, Kerrin S, Fernando, Michelle M A, Cunninghame Graham, Deborah S, Vyse, Timothy J
Published in Nature communications (15.05.2019)
Published in Nature communications (15.05.2019)
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Bidirectional Allosteric Coupling between PIP2 Binding and the Pore of the Oncochannel TRPV6
Humer, Christina, Radiskovic, Tamara, Horváti, Kata, Lindinger, Sonja, Groschner, Klaus, Romanin, Christoph, Höglinger, Carmen
Published in International journal of molecular sciences (01.01.2024)
Published in International journal of molecular sciences (01.01.2024)
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Photocrosslinking-induced CRAC channel-like Orai1 activation independent of STIM1
Maltan, Lena, Weiß, Sarah, Najjar, Hadil, Leopold, Melanie, Lindinger, Sonja, Höglinger, Carmen, Höbarth, Lorenz, Sallinger, Matthias, Grabmayr, Herwig, Berlansky, Sascha, Krivic, Denis, Hopl, Valentina, Blaimschein, Anna, Fahrner, Marc, Frischauf, Irene, Tiffner, Adéla, Derler, Isabella
Published in Nature communications (08.03.2023)
Published in Nature communications (08.03.2023)
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Journal Article
TRPV6 Regulation by Cis-22a and Cholesterol
Humer, Christina, Lindinger, Sonja, Carrel, Aline L., Romanin, Christoph, Höglinger, Carmen
Published in Biomolecules (Basel, Switzerland) (08.06.2022)
Published in Biomolecules (Basel, Switzerland) (08.06.2022)
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Journal Article
Bidirectional Allosteric Coupling between PIP[sub.2] Binding and the Pore of the Oncochannel TRPV6
Humer, Christina, Radiskovic, Tamara, Horváti, Kata, Lindinger, Sonja, Groschner, Klaus, Romanin, Christoph, Höglinger, Carmen
Published in International journal of molecular sciences (01.01.2024)
Published in International journal of molecular sciences (01.01.2024)
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Journal Article
CRAC channel opening is determined by a series of Orai1 gating checkpoints in the transmembrane and cytosolic regions
Tiffner, Adéla, Schober, Romana, Höglinger, Carmen, Bonhenry, Daniel, Pandey, Saurabh, Lunz, Victoria, Sallinger, Matthias, Frischauf, Irene, Fahrner, Marc, Lindinger, Sonja, Maltan, Lena, Berlansky, Sascha, Stadlbauer, Michael, Schindl, Rainer, Ettrich, Rudiger, Romanin, Christoph, Derler, Isabella
Published in The Journal of biological chemistry (01.01.2021)
Published in The Journal of biological chemistry (01.01.2021)
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Journal Article
A novel STIM1-Orai1 gating interface essential for CRAC channel activation
Butorac, Carmen, Muik, Martin, Derler, Isabella, Stadlbauer, Michael, Lunz, Victoria, Krizova, Adéla, Lindinger, Sonja, Schober, Romana, Frischauf, Irene, Bhardwaj, Rajesh, Hediger, Matthias A., Groschner, Klaus, Romanin, Christoph
Published in Cell calcium (Edinburgh) (01.05.2019)
Published in Cell calcium (Edinburgh) (01.05.2019)
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Journal Article
Interplay of CRAC Channels with Ca2+ Activated K+ Channels
Krizova, Adela, Schober, Romana, Lindinger, Sonja, Butorac, Carmen, Romanin, Christoph, Derler, Isabella
Published in Biophysical journal (02.02.2018)
Published in Biophysical journal (02.02.2018)
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Journal Article
Bidirectional Allosteric Coupling between PIP 2 Binding and the Pore of the Oncochannel TRPV6
Humer, Christina, Radiskovic, Tamara, Horváti, Kata, Lindinger, Sonja, Groschner, Klaus, Romanin, Christoph, Höglinger, Carmen
Published in International journal of molecular sciences (03.01.2024)
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Published in International journal of molecular sciences (03.01.2024)
Journal Article
Lipid-independent control of endothelial and neuronal TRPC3 channels by light
Tiapko, Oleksandra, Shrestha, Niroj, Lindinger, Sonja, de la Cruz, Gema Guedes, Graziani, Annarita, Klec, Christiane, Butorac, Carmen, Graier, Wolfgang. F., Kubista, Helmut, Freichel, Marc, Birnbaumer, Lutz, Romanin, Christoph, Glasnov, Toma, Groschner, Klaus
Published in Chemical science (Cambridge) (07.03.2019)
Published in Chemical science (Cambridge) (07.03.2019)
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Journal Article
Natural product inspired optimization of a selective TRPV6 calcium channel inhibitor
Cunha, Micael Rodrigues, Bhardwaj, Rajesh, Carrel, Aline Lucie, Lindinger, Sonja, Romanin, Christoph, Parise-Filho, Roberto, Hediger, Matthias A, Reymond, Jean-Louis
Published in MedChemComm (01.09.2020)
Published in MedChemComm (01.09.2020)
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Journal Article
Photoswitchable Inhibitor of the Calcium Channel TRPV6
Cunha, Micael R, Bhardwaj, Rajesh, Lindinger, Sonja, Butorac, Carmen, Romanin, Christoph, Hediger, Matthias A, Reymond, Jean-Louis
Published in ACS medicinal chemistry letters (12.09.2019)
Published in ACS medicinal chemistry letters (12.09.2019)
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Journal Article
Lipid-independent control of endothelial and neuronal TRPC3 channels by lightElectronic supplementary information (ESI) available. See DOI: 10.1039/c8sc05536j
Tiapko, Oleksandra, Shrestha, Niroj, Lindinger, Sonja, Guedes de la Cruz, Gema, Graziani, Annarita, Klec, Christiane, Butorac, Carmen, Graier, Wolfgang. F, Kubista, Helmut, Freichel, Marc, Birnbaumer, Lutz, Romanin, Christoph, Glasnov, Toma, Groschner, Klaus
Year of Publication 27.02.2019
Year of Publication 27.02.2019
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Journal Article
Lipid-independent control of endothelial and neuronal TRPC3 channels by light† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c8sc05536j
Tiapko, Oleksandra, Shrestha, Niroj, Lindinger, Sonja, Guedes de la Cruz, Gema, Graziani, Annarita, Klec, Christiane, Butorac, Carmen, Graier, Wolfgang. F., Kubista, Helmut, Freichel, Marc, Birnbaumer, Lutz, Romanin, Christoph, Glasnov, Toma, Groschner, Klaus
Published in Chemical science (Cambridge) (15.01.2019)
Published in Chemical science (Cambridge) (15.01.2019)
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Journal Article
Inactivation-mimicking block of the epithelial calcium channel TRPV6
Bhardwaj, Rajesh, Lindinger, Sonja, Neuberger, Arthur, Nadezhdin, Kirill D, Singh, Appu K, Cunha, Micael R, Derler, Isabella, Gyimesi, Gergely, Reymond, Jean-Louis, Hediger, Matthias A, Romanin, Christoph, Sobolevsky, Alexander I
Published in Science advances (27.11.2020)
Published in Science advances (27.11.2020)
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Journal Article
Natural product inspired optimization of a selective TRPV6 calcium channel inhibitor† †Electronic supplementary information (ESI) available: Tables S1–S3, Fig. S1–S4, protocols for FLIPR assays, confocal imaging and antiproliferative assays, preparation, crystal structure reports, HRMS results, 1H, 13C and 19F NMR spectra of all new compounds, and purity of final compounds. CCDC 1997201–1997205. For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/d0md00145g
Cunha, Micael Rodrigues, Bhardwaj, Rajesh, Carrel, Aline Lucie, Lindinger, Sonja, Romanin, Christoph, Parise-Filho, Roberto, Hediger, Matthias A., Reymond, Jean-Louis
Published in RSC medicinal chemistry (16.07.2020)
Published in RSC medicinal chemistry (16.07.2020)
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Journal Article
A series of Orai1 gating checkpoints in transmembrane and cytosolic regions requires clearance for CRAC channel opening / Clearance and synergy of Orai1 gating checkpoints controls pore opening
Tiffner, Adela, Schober, Romana, Hoeglinger, Carmen, Bonhenry, Daniel, Pandey, Saurabh, Lunz, Victoria, Sallinger, Matthias, Frischauf, Irene, Fahrner, Marc, Lindinger, Sonja, Maltan, Lena, Berlansky, Sascha, Stadlbauer, Michael, Schindl, Rainer, Ettrich, Rudi, Romanin, Christoph, Derler, Isabella
Published in bioRxiv (17.07.2020)
Published in bioRxiv (17.07.2020)
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