Development of Pilot-Scale Continuous Production of an LY2886721 Starting Material by Packed-Bed Hydrogenolysis
Zaborenko, Nikolay, Linder, Ryan J, Braden, Timothy M, Campbell, Bradley M, Hansen, Marvin M, Johnson, Martin D
Published in Organic process research & development (18.09.2015)
Published in Organic process research & development (18.09.2015)
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Journal Article
Boronic Acids and DerivativesProbing the Structure–Activity Relationships for Mutagenicity
Hansen, Marvin M, Jolly, Robert A, Linder, Ryan J
Published in Organic process research & development (20.11.2015)
Published in Organic process research & development (20.11.2015)
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Journal Article
Identification of LY3522348: A Highly Selective and Orally Efficacious Ketohexokinase Inhibitor
Durham, Timothy B., Hao, Junliang, Spinazze, Patrick, Stack, Douglas R., Toth, James L., Massey, Steven, Mbofana, Curren T., Johnston, Richard D., Lineswala, Jayana P., Wrobleski, Aaron, Mínguez, Jose Miguel, Perez, Carlos, Smith, Daryl L., Lamar, Jason, Leon, Rebecca, Corkins, Christopher, Durbin, Jim, Tung, Frances, Guo, Sherry, Linder, Ryan J., Yumibe, Nathan, Wang, Wei, MacKrell, James, Antonellis, Meghan, Mascaro, Bethany
Published in Journal of medicinal chemistry (14.12.2023)
Published in Journal of medicinal chemistry (14.12.2023)
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Journal Article
Double Heck Route to a Dibenzoxepine and Convergent Suzuki Cross-Coupling Strategy for the Synthesis of an MR Antagonist
Hansen, Marvin M, Kallman, Neil J, Koenig, Thomas M, Linder, Ryan J, Richey, Rachel N, Rizzo, John R, Ward, Jeffrey A, Yu, Hannah, Zhang, Tony Y, Mitchell, David
Published in Organic process research & development (17.02.2017)
Published in Organic process research & development (17.02.2017)
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Journal Article
Synthesis of BACE Inhibitor LY2886721. Part II. Isoxazolidines as Precursors to Chiral Aminothiazines, Selective Peptide Coupling, and a Controlled Reactive Crystallization
Hansen, Marvin M, Jarmer, Daniel J, Arslantas, Enver, DeBaillie, Amy C, Frederick, Andrea L, Harding, Molly, Hoard, David W, Hollister, Adrienne, Huber, Dominique, Kolis, Stanley P, Kuehne-Willmore, Jennifer E, Kull, Thomas, Laurila, Michael E, Linder, Ryan J, Martin, Thomas J, Martinelli, Joseph R, McCulley, Michael J, Richey, Rachel N, Starkey, Derek R, Ward, Jeffrey A, Zaborenko, Nikolay, Zweifel, Theo
Published in Organic process research & development (18.09.2015)
Published in Organic process research & development (18.09.2015)
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Journal Article
Route Design and Development of a MET Kinase Inhibitor: A Copper-Catalyzed Preparation of an N1-Methylindazole
Kallman, Neil J, Liu, Chin, Yates, Matthew H, Linder, Ryan J, Ruble, J. Craig, Kogut, Eugene F, Patterson, Lawrence E, Laird, Dana L. T, Hansen, Marvin M
Published in Organic process research & development (01.04.2014)
Published in Organic process research & development (01.04.2014)
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Journal Article
Synthesis of BACE Inhibitor LY2886721. Part I. An Asymmetric Nitrone Cycloaddition Strategy
Kolis, Stanley P, Hansen, Marvin M, Arslantas, Enver, Brändli, Lukas, Buser, Jonas, DeBaillie, Amy C, Frederick, Andrea L, Hoard, David W, Hollister, Adrienne, Huber, Dominique, Kull, Thomas, Linder, Ryan J, Martin, Thomas J, Richey, Rachel N, Stutz, Alfred, Waibel, Michael, Ward, Jeffrey A, Zamfir, Alexandru
Published in Organic process research & development (18.09.2015)
Published in Organic process research & development (18.09.2015)
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Journal Article
Design, Development, and Scale-Up of a Selective meso-Epoxide Desymmetrization Process
Varie, David L, Beck, Christopher, Borders, Sandra K, Brady, Molly D, Cronin, Jason S, Ditsworth, Tracy K, Hay, David A, Hoard, David W, Hoying, Richard C, Linder, Ryan J, Miller, Richard D, Moher, Eric D, Remacle, Jacob R, Rieck, John A, Anderson, David D, Dodson, Paul N, Forst, Mindy B, Pierson, Duane A, Turpin, Joseph A
Published in Organic process research & development (01.05.2007)
Published in Organic process research & development (01.05.2007)
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Journal Article
Development of a Practical Synthesis of an Aminoindanol-Derived M1 Agonist
Hansen, Marvin M, Borders, Sandra S. K, Clayton, Marcella T, Heath, Perry C, Kolis, Stanley P, Larsen, Samuel D, Linder, Ryan J, Reutzel-Edens, Susan M, Smith, Justin C, Tameze, Shella L, Ward, Jeffrey A, Weigel, Leland O
Published in Organic process research & development (20.03.2009)
Published in Organic process research & development (20.03.2009)
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Journal Article
Abstract 1259: Preclinical characterization of LY3537982, a novel, highly selective and potent KRAS-G12C inhibitor
Peng, Sheng-Bin, Si, Chong, Zhang, Youyan, Van Horn, Robert D., Lin, Xi, Gong, Xueqian, Huber, Lysiane, Donoho, Gregory, Curtis, Carmen, Strelow, John M., Bocchinfuso, Wayne P., Guo, Deqi, Boulet, Serge L., Barda, David, Manglicmot, Danalyn, Saflor, Melbert-Brian D., Wang, Jing, Xiao, Junpeng, Chalmers, Michael J., Burns, Lee, Linder, Ryan J., Ackermann, Bradley L., Cornwell, Paul D., Zhou, Lian, McCann, Denis, Henry, James
Published in Cancer research (Chicago, Ill.) (01.07.2021)
Published in Cancer research (Chicago, Ill.) (01.07.2021)
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Journal Article
Route Design and Development of a MET Kinase Inhibitor: A Copper-Catalyzed Preparation of an N 1 - Methylindazole
Kallman, Neil J., Liu, Chin, Yates, Matthew H., Linder, Ryan J., Ruble, J. Craig, Kogut, Eugene F., Patterson, Lawrence E., Laird, Dana L. T., Hansen, Marvin M.
Published in Organic process research & development (18.04.2014)
Published in Organic process research & development (18.04.2014)
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Journal Article
Diastereoselective sulfur ylide promoted aldol/epoxidation
Hansen, Jeffrey A., Smith, Colin R., Linder, Ryan J., Huffman, John C.
Published in Tetrahedron letters (02.10.2006)
Published in Tetrahedron letters (02.10.2006)
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Journal Article
Diastereoselective Sulfur Ylide Promoted Aldol/Epoxidation
Hansen, Jeffrey A., Smith, Colin R., Linder, Ryan J., Huffman, John C.
Published in ChemInform (09.01.2007)
Published in ChemInform (09.01.2007)
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Journal Article