Investigation of a Pharmacological Approach for Reduction of Renal Uptake of Radiolabeled ADAPT Scaffold Protein
Vorobyeva, Anzhelika, Oroujeni, Maryam, Lindbo, Sarah, Hober, Sophia, Xu, Tianqi, Liu, Yongsheng, Rinne, Sara S, Garousi, Javad
Published in Molecules (Basel, Switzerland) (28.09.2020)
Published in Molecules (Basel, Switzerland) (28.09.2020)
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Journal Article
Direct In Vivo Comparison of 99mTc-Labeled Scaffold Proteins, DARPin G3 and ADAPT6, for Visualization of HER2 Expression and Monitoring of Early Response for Trastuzumab Therapy
Tolmachev, Vladimir, Bodenko, Vitalina, Oroujeni, Maryam, Deyev, Sergey, Konovalova, Elena, Schulga, Alexey, Lindbo, Sarah, Hober, Sophia, Bragina, Olga, Orlova, Anna, Vorobyeva, Anzhelika
Published in International journal of molecular sciences (02.12.2022)
Published in International journal of molecular sciences (02.12.2022)
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Journal Article
HER2-Specific Pseudomonas Exotoxin A PE25 Based Fusions: Influence of Targeting Domain on Target Binding, Toxicity, and In Vivo Biodistribution
Ding, Haozhong, Altai, Mohamed, Yin, Wen, Lindbo, Sarah, Liu, Hao, Garousi, Javad, Xu, Tianqi, Orlova, Anna, Tolmachev, Vladimir, Hober, Sophia, Gräslund, Torbjörn
Published in Pharmaceutics (24.04.2020)
Published in Pharmaceutics (24.04.2020)
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Journal Article
Bispecific applications of non-immunoglobulin scaffold binders
Hober, Sophia, Lindbo, Sarah, Nilvebrant, Johan
Published in Methods (San Diego, Calif.) (01.02.2019)
Published in Methods (San Diego, Calif.) (01.02.2019)
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Journal Article
Phase I Study of 99mTc-ADAPT6, a Scaffold Protein–Based Probe for Visualization of HER2 Expression in Breast Cancer
Bragina, Olga, von Witting, Emma, Garousi, Javad, Zelchan, Roman, Sandström, Mattias, Orlova, Anna, Medvedeva, Anna, Doroshenko, Artem, Vorobyeva, Anzhelika, Lindbo, Sarah, Borin, Jesper, Tarabanovskaya, Natalya, Sörensen, Jens, Hober, Sophia, Chernov, Vladimir, Tolmachev, Vladimir
Published in The Journal of nuclear medicine (1978) (01.04.2021)
Published in The Journal of nuclear medicine (1978) (01.04.2021)
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Journal Article
Phase I Study of Tc-99(m)-ADAPT6, a Scaffold Protein-Based Probe for Visualization of HER2 Expression in Breast Cancer
Bragina, Olga, von Witting, Emma, Garousi, Javad, Zelchan, Roman, Sandstrom, Mattias, Orlova, Anna, Medvedeva, Anna, Doroshenko, Artem, Vorobyeva, Anzhelika, Lindbo, Sarah, Borin, Jesper, Tarabanovskaya, Natalya, Sorensen, Jens, Hober, Sophia, Chernov, Vladimir, Tolmachev, Vladimir
Published in The Journal of nuclear medicine (1978) (01.04.2021)
Published in The Journal of nuclear medicine (1978) (01.04.2021)
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Journal Article
Radionuclide Tumor Targeting Using ADAPT Scaffold Proteins: Aspects of Label Positioning and Residualizing Properties of the Label
Lindbo, Sarah, Garousi, Javad, Mitran, Bogdan, Altai, Mohamed, Buijs, Jos, Orlova, Anna, Hober, Sophia, Tolmachev, Vladimir
Published in Journal of Nuclear Medicine (01.01.2018)
Published in Journal of Nuclear Medicine (01.01.2018)
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Journal Article
Influence of Histidine-Containing Tags on the Biodistribution of ADAPT Scaffold Proteins
Lindbo, Sarah, Garousi, Javad, Åstrand, Mikael, Honarvar, Hadis, Orlova, Anna, Hober, Sophia, Tolmachev, Vladimir
Published in Bioconjugate chemistry (16.03.2016)
Published in Bioconjugate chemistry (16.03.2016)
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Journal Article
Optimized Molecular Design of ADAPT-Based HER2-Imaging Probes Labeled with 111In and 68Ga
Lindbo, Sarah, Garousi, Javad, Mitran, Bogdan, Vorobyeva, Anzhelika, Oroujeni, Maryam, Orlova, Anna, Hober, Sophia, Tolmachev, Vladimir
Published in Molecular pharmaceutics (02.07.2018)
Published in Molecular pharmaceutics (02.07.2018)
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Journal Article
ADAPT, a Novel Scaffold Protein-Based Probe for Radionuclide Imaging of Molecular Targets That Are Expressed in Disseminated Cancers
Garousi, Javad, Lindbo, Sarah, Nilvebrant, Johan, Åstrand, Mikael, Buijs, Jos, Sandström, Mattias, Honarvar, Hadis, Orlova, Anna, Tolmachev, Vladimir, Hober, Sophia
Published in Cancer research (Chicago, Ill.) (15.10.2015)
Published in Cancer research (Chicago, Ill.) (15.10.2015)
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Journal Article
Comparative evaluation of tumor targeting using the anti-HER2 ADAPT scaffold protein labeled at the C-terminus with indium-111 or technetium-99m
Garousi, Javad, Lindbo, Sarah, Mitran, Bogdan, Buijs, Jos, Vorobyeva, Anzhelika, Orlova, Anna, Tolmachev, Vladimir, Hober, Sophia
Published in Scientific reports (07.11.2017)
Published in Scientific reports (07.11.2017)
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Journal Article
Selection of the optimal macrocyclic chelators for labeling with 111In and 68Ga improves contrast of HER2 imaging using engineered scaffold protein ADAPT6
von Witting, Emma, Garousi, Javad, Lindbo, Sarah, Vorobyeva, Anzhelika, Altai, Mohamed, Oroujeni, Maryam, Mitran, Bogdan, Orlova, Anna, Hober, Sophia, Tolmachev, Vladimir
Published in European journal of pharmaceutics and biopharmaceutics (01.07.2019)
Published in European journal of pharmaceutics and biopharmaceutics (01.07.2019)
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Journal Article
Comparative evaluation of dimeric and monomeric forms of ADAPT scaffold protein for targeting of HER2-expressing tumours
Garousi, Javad, Lindbo, Sarah, Borin, Jesper, von Witting, Emma, Vorobyeva, Anzhelika, Oroujeni, Maryam, Mitran, Bogdan, Orlova, Anna, Buijs, Jos, Tolmachev, Vladimir, Hober, Sophia
Published in European journal of pharmaceutics and biopharmaceutics (01.01.2019)
Published in European journal of pharmaceutics and biopharmaceutics (01.01.2019)
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Journal Article
Direct In Vivo Comparison of Tc-99m-Labeled Scaffold Proteins, DARPin G3 and ADAPT6, for Visualization of HER2 Expression and Monitoring of Early Response for Trastuzumab Therapy
Tolmachev, Vladimir, Bodenko, Vitalina, Oroujeni, Maryam, Deyev, Sergey, Konovalova, Elena, Schulga, Alexey, Lindbo, Sarah, Hober, Sophia, Bragina, Olga, Orlova, Anna, Vorobyeva, Anzhelika
Published in International journal of molecular sciences (01.12.2022)
Published in International journal of molecular sciences (01.12.2022)
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Journal Article
Correction to “Small Bispecific Affinity Proteins for Simultaneous Target Binding and Albumin-Associated Half-Life Extension”
von Witting, Emma, Lindbo, Sarah, Lundqvist, Magnus, Möller, Marit, Wisniewski, Andreas, Kanje, Sara, Rockberg, Johan, Tegel, Hanna, Åstrand, Mikael, Uhlén, Mathias, Hober, Sophia
Published in Molecular pharmaceutics (05.09.2022)
Published in Molecular pharmaceutics (05.09.2022)
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Journal Article
Direct In Vivo Comparison of 99m Tc-Labeled Scaffold Proteins, DARPin G3 and ADAPT6, for Visualization of HER2 Expression and Monitoring of Early Response for Trastuzumab Therapy
Tolmachev, Vladimir, Bodenko, Vitalina, Oroujeni, Maryam, Deyev, Sergey, Konovalova, Elena, Schulga, Alexey, Lindbo, Sarah, Hober, Sophia, Bragina, Olga, Orlova, Anna, Vorobyeva, Anzhelika
Published in International journal of molecular sciences (02.12.2022)
Published in International journal of molecular sciences (02.12.2022)
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Journal Article
An easy-to-use high-throughput selection system for the discovery of recombinant protein binders from alternative scaffold libraries
Möller, Marit, Jönsson, Malin, Lundqvist, Magnus, Hedin, Blenda, Larsson, Louise, Larsson, Emma, Rockberg, Johan, Uhlén, Mathias, Lindbo, Sarah, Tegel, Hanna, Hober, Sophia
Published in Protein engineering, design and selection (21.01.2023)
Published in Protein engineering, design and selection (21.01.2023)
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Journal Article
Potent and specific fusion toxins consisting of a HER2‑binding, ABD‑derived affinity protein, fused to truncated versions of Pseudomonas exotoxin A
Liu, Hao, Lindbo, Sarah, Ding, Haozhong, Altai, Mohamed, Garousi, Javad, Orlova, Anna, Tolmachev, Vladimir, Hober, Sophia, Gräslund, Torbjörn
Published in International journal of oncology (01.07.2019)
Published in International journal of oncology (01.07.2019)
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Journal Article
Influence of the N‑Terminal Composition on Targeting Properties of Radiometal-Labeled Anti-HER2 Scaffold Protein ADAPT6
Garousi, Javad, Lindbo, Sarah, Honarvar, Hadis, Velletta, Justin, Mitran, Bogdan, Altai, Mohamed, Orlova, Anna, Tolmachev, Vladimir, Hober, Sophia
Published in Bioconjugate chemistry (16.11.2016)
Published in Bioconjugate chemistry (16.11.2016)
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Journal Article