Functionally selective signaling and broad metabolic benefits by novel insulin receptor partial agonists
Wu, Margaret, Carballo-Jane, Ester, Zhou, Haihong, Zafian, Peter, Dai, Ge, Liu, Mindy, Lao, Julie, Kelly, Terri, Shao, Dan, Gorski, Judith, Pissarnitski, Dmitri, Kekec, Ahmet, Chen, Ying, Previs, Stephen F., Scapin, Giovanna, Gomez-Llorente, Yacob, Hollingsworth, Scott A., Yan, Lin, Feng, Danqing, Huo, Pei, Walford, Geoffrey, Erion, Mark D., Kelley, David E., Lin, Songnian, Mu, James
Published in Nature communications (17.02.2022)
Published in Nature communications (17.02.2022)
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Design-rules for stapled peptides with in vivo activity and their application to Mdm2/X antagonists
Chandramohan, Arun, Josien, Hubert, Yuen, Tsz Ying, Duggal, Ruchia, Spiegelberg, Diana, Yan, Lin, Juang, Yu-Chi Angela, Ge, Lan, Aronica, Pietro G., Kaan, Hung Yi Kristal, Lim, Yee Hwee, Peier, Andrea, Sherborne, Brad, Hochman, Jerome, Lin, Songnian, Biswas, Kaustav, Nestor, Marika, Verma, Chandra S., Lane, David P., Sawyer, Tomi K., Garbaccio, Robert, Henry, Brian, Kannan, Srinivasaraghavan, Brown, Christopher J., Johannes, Charles W., Partridge, Anthony W.
Published in Nature communications (12.01.2024)
Published in Nature communications (12.01.2024)
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Author Correction: Functionally selective signaling and broad metabolic benefits by novel insulin receptor partial agonists
Wu, Margaret, Carballo-Jane, Ester, Zhou, Haihong, Zafian, Peter, Dai, Ge, Liu, Mindy, Lao, Julie, Kelly, Terri, Shao, Dan, Gorski, Judith, Pissarnitski, Dmitri, Kekec, Ahmet, Chen, Ying, Previs, Stephen F., Scapin, Giovanna, Gomez-Llorente, Yacob, Hollingsworth, Scott A., Yan, Lin, Feng, Danqing, Huo, Pei, Walford, Geoffrey, Erion, Mark D., Kelley, David E., Lin, Songnian, Mu, James
Published in Nature communications (23.01.2024)
Published in Nature communications (23.01.2024)
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Journal Article
Glucagon receptor antagonism induces increased cholesterol absorption[S]
Guan, Hong-Ping, Yang, Xiaodong, Lu, Ku, Wang, Sheng-Ping, Castro-Perez, Jose M., Previs, Stephen, Wright, Michael, Shah, Vinit, Herath, Kithsiri, Xie, Dan, Szeto, Daphne, Forrest, Gail, Xiao, Jing Chen, Palyha, Oksana, Sun, Li-Ping, Andryuk, Paula J., Engel, Samuel S., Xiong, Yusheng, Lin, Songnian, Kelley, David E., Erion, Mark D., Davis, Harry R., Wang, Liangsu
Published in Journal of lipid research (01.11.2015)
Published in Journal of lipid research (01.11.2015)
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In Situ Forming Injectable Thermoresponsive Hydrogels for Controlled Delivery of Biomacromolecules
Dutta, Kingshuk, Das, Ritam, Ling, Jing, Monibas, Rafael Mayoral, Carballo-Jane, Ester, Kekec, Ahmet, Feng, Danqing Dennis, Lin, Songnian, Mu, James, Saklatvala, Robert, Thayumanavan, S, Liang, Yingkai
Published in ACS omega (21.07.2020)
Published in ACS omega (21.07.2020)
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Selective Small-Molecule Agonists of G Protein–Coupled Receptor 40 Promote Glucose-Dependent Insulin Secretion and Reduce Blood Glucose in Mice
Tan, Carina P, Feng, Yue, Zhou, Yun-Ping, Eiermann, George J, Petrov, Aleksandr, Zhou, Changyou, Lin, Songnian, Salituro, Gino, Meinke, Peter, Mosley, Ralph, Akiyama, Taro E, Einstein, Monica, Kumar, Sanjeev, Berger, Joel P, Mills, Sander G, Thornberry, Nancy A, Yang, Lihu, Howard, Andrew D
Published in Diabetes (New York, N.Y.) (01.08.2008)
Published in Diabetes (New York, N.Y.) (01.08.2008)
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Journal Article
Site-Selective Synthesis of Insulin Azides and Bioconjugates
Boga, Sobhana Babu, Krska, Shane W, Lin, Songnian, Pissarnitski, Dmitri, Yan, Lin, Kekec, Ahmet, Tang, Weijuan, Pierson, Nicholas A, Strulson, Christopher A, Streckfuss, Eric, Zhu, Xiaohong, Zhang, Xiaoping, Kelly, Terri, Parish, Craig A
Published in Bioconjugate chemistry (17.04.2019)
Published in Bioconjugate chemistry (17.04.2019)
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Journal Article
Late-stage lipidation of fully elaborated tryptophan-containing peptides for improved pharmacokinetics
Huang, Chunhui, Wille, Cannon B., He, Huaibing, Reddy, Vijay Bhasker Gangula, Nargund, Ravi P., Lin, Songnian, Palani, Anandan
Published in Tetrahedron letters (22.03.2017)
Published in Tetrahedron letters (22.03.2017)
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Journal Article
Design, Synthesis, and Biological Evaluation of New-Generation Taxoids
Ojima, Iwao, Chen, Jin, Sun, Liang, Borella, Christopher P, Wang, Tao, Miller, Michael L, Lin, Songnian, Geng, Xudong, Kuznetsova, Larisa, Qu, Chuanxing, Gallager, David, Zhao, Xianrui, Zanardi, Ilaria, Xia, Shujun, Horwitz, Susan B, Mallen-St. Clair, Jon, Guerriero, Jennifer L, Bar-Sagi, Dafna, Veith, Jean M, Pera, Paula, Bernacki, Ralph J
Published in Journal of medicinal chemistry (12.06.2008)
Published in Journal of medicinal chemistry (12.06.2008)
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Journal Article
Total Synthesis of TMC-95A and -B via a New Reaction Leading to Z-Enamides. Some Preliminary Findings as to SAR
Lin, Songnian, Yang, Zhi-Qiang, Kwok, Benjamin H. B, Koldobskiy, Michael, Crews, Craig M, Danishefsky, Samuel J
Published in Journal of the American Chemical Society (26.05.2004)
Published in Journal of the American Chemical Society (26.05.2004)
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Journal Article
Synthesis of the Functionalized Macrocyclic Core of Proteasome Inhibitors TMC-95A and B
Lin, Songnian, Danishefsky, Samuel J.
Published in Angewandte Chemie International Edition (18.05.2001)
Published in Angewandte Chemie International Edition (18.05.2001)
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Discovery of 5-aryloxy-2,4-thiazolidinediones as potent GPR40 agonists
Zhou, Changyou, Tang, Cheng, Chang, Eric, Ge, Min, Lin, Songnian, Cline, Eric, Tan, Carina P., Feng, Yue, Zhou, Yun-Ping, Eiermann, George J., Petrov, Aleksandr, Salituro, Gino, Meinke, Peter, Mosley, Ralph, Akiyama, Taro E., Einstein, Monica, Kumar, Sanjeev, Berger, Joel, Howard, Andrew D., Thornberry, Nancy, Mills, Sander G., Yang, Lihu
Published in Bioorganic & medicinal chemistry letters (01.02.2010)
Published in Bioorganic & medicinal chemistry letters (01.02.2010)
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Pharmacokinetic and pharmacodynamic properties of the glucokinase activator MK-0941 in rodent models of type 2 diabetes and healthy dogs
Eiki, Jun-ichi, Nagata, Yasufumi, Futamura, Mayumi, Sasaki-Yamamoto, Kaori, Iino, Tomoharu, Nishimura, Teruyuki, Chiba, Masato, Ohyama, Sumika, Yoshida-Yoshimioto, Riki, Fujii, Kenji, Hosaka, Hideka, Goto-Shimazaki, Hiroko, Kadotani, Akito, Ohe, Tomoyuki, Lin, Songnian, Langdon, Ronald B, Berger, Joel P
Published in Molecular pharmacology (01.12.2011)
Published in Molecular pharmacology (01.12.2011)
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Journal Article
Total Synthesis of Guanacastepene A: A Route to Enantiomeric Control
Mandal, Mihirbaran, Yun, Heedong, Dudley, Gregory B, Lin, Songnian, Tan, Derek S, Danishefsky, Samuel J
Published in Journal of organic chemistry (23.12.2005)
Published in Journal of organic chemistry (23.12.2005)
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Journal Article
A Common Pharmacophore for Cytotoxic Natural Products That Stabilize Microtubules
Ojima, Iwao, Chakravarty, Subrata, Inoue, Tadashi, Lin, Songnian, He, Lifeng, Horwitz, Susan Band, Kuduk, Scott D., Danishefsky, Samuel J.
Published in Proceedings of the National Academy of Sciences - PNAS (13.04.1999)
Published in Proceedings of the National Academy of Sciences - PNAS (13.04.1999)
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Journal Article
Synthesis of Novel C2−C3‘N-Linked Macrocyclic Taxoids by Means of Highly Regioselective Heck Macrocyclization
Geng, Xudong, Miller, Michael L, Lin, Songnian, Ojima, Iwao
Published in Organic letters (02.10.2003)
Published in Organic letters (02.10.2003)
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Novel 1-(2-aminopyrazin-3-yl)methyl-2-thioureas as potent inhibitors of mitogen-activated protein kinase-activated protein kinase 2 (MK-2)
Lin, Songnian, Lombardo, Matthew, Malkani, Sunita, Hale, Jeffrey J., Mills, Sander G., Chapman, Kevin, Thompson, James E., Zhang, Wen Xiao, Wang, Ruixiu, Cubbon, Rose M., O’Neill, Edward A., Luell, Silvi, Carballo-Jane, Ester, Yang, Lihu
Published in Bioorganic & medicinal chemistry letters (15.06.2009)
Published in Bioorganic & medicinal chemistry letters (15.06.2009)
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Annotated Bibliography of Dr. Arthur A. Patchett
Nargund, Ravi, Wyvratt, Matthew, Lin, Songnian, Sebhat, Iyassu, Greenlee, William
Published in Journal of medicinal chemistry (14.12.2023)
Published in Journal of medicinal chemistry (14.12.2023)
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