Antibody Persistence through 6 Months after the Second Dose of mRNA-1273 Vaccine for Covid-19
Doria-Rose, Nicole, Suthar, Mehul S, Makowski, Mat, O’Connell, Sarah, McDermott, Adrian B, Flach, Britta, Ledgerwood, Julie E, Mascola, John R, Graham, Barney S, Lin, Bob C, O’Dell, Sijy, Schmidt, Stephen D, Widge, Alicia T, Edara, Venkata-Viswanadh, Anderson, Evan J, Lai, Lilin, Floyd, Katharine, Rouphael, Nadine G, Zarnitsyna, Veronika, Roberts, Paul C, Makhene, Mamodikoe, Buchanan, Wendy, Luke, Catherine J, Beigel, John H, Jackson, Lisa A, Neuzil, Kathleen M, Bennett, Hamilton, Leav, Brett, Albert, Jim, Kunwar, Pratap
Published in New England Journal of Medicine (10.06.2021)
Published in New England Journal of Medicine (10.06.2021)
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Immune correlates analysis of the mRNA-1273 COVID-19 vaccine efficacy clinical trial
Gilbert, Peter B, Montefiori, David C, McDermott, Adrian B, Fong, Youyi, Benkeser, David, Deng, Weiping, Zhou, Honghong, Houchens, Christopher R, Martins, Karen, Jayashankar, Lakshmi, Castellino, Flora, Flach, Britta, Lin, Bob C, O'Connell, Sarah, McDanal, Charlene, Eaton, Amanda, Sarzotti-Kelsoe, Marcella, Lu, Yiwen, Yu, Chenchen, Borate, Bhavesh, van der Laan, Lars W P, Hejazi, Nima S, Huynh, Chuong, Miller, Jacqueline, El Sahly, Hana M, Baden, Lindsey R, Baron, Mira, De La Cruz, Luis, Gay, Cynthia, Kalams, Spyros, Kelley, Colleen F, Andrasik, Michele P, Kublin, James G, Corey, Lawrence, Neuzil, Kathleen M, Carpp, Lindsay N, Pajon, Rolando, Follmann, Dean, Donis, Ruben O, Koup, Richard A
Published in Science (American Association for the Advancement of Science) (07.01.2022)
Published in Science (American Association for the Advancement of Science) (07.01.2022)
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Human CD4-binding site antibody elicited by polyvalent DNA prime-protein boost vaccine neutralizes cross-clade tier-2-HIV strains
Wang, Shixia, Chan, Kun-Wei, Wei, Danlan, Ma, Xiuwen, Liu, Shuying, Hu, Guangnan, Park, Saeyoung, Pan, Ruimin, Gu, Ying, Nazzari, Alexandra F., Olia, Adam S., Xu, Kai, Lin, Bob C., Louder, Mark K., McKee, Krisha, Doria-Rose, Nicole A., Montefiori, David, Seaman, Michael S., Zhou, Tongqing, Kwong, Peter D., Arthos, James, Kong, Xiang-Peng, Lu, Shan
Published in Nature communications (21.05.2024)
Published in Nature communications (21.05.2024)
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Improved HIV-1 neutralization breadth and potency of V2-apex antibodies by in silico design
Holt, Graham T., Gorman, Jason, Wang, Siyu, Lowegard, Anna U., Zhang, Baoshan, Liu, Tracy, Lin, Bob C., Louder, Mark K., Frenkel, Marcel S., McKee, Krisha, O’Dell, Sijy, Rawi, Reda, Shen, Chen-Hsiang, Doria-Rose, Nicole A., Kwong, Peter D., Donald, Bruce R.
Published in Cell reports (Cambridge) (25.07.2023)
Published in Cell reports (Cambridge) (25.07.2023)
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Extended antibody-framework-to-antigen distance observed exclusively with broad HIV-1-neutralizing antibodies recognizing glycan-dense surfaces
Lee, Myungjin, Changela, Anita, Gorman, Jason, Rawi, Reda, Bylund, Tatsiana, Chao, Cara W., Lin, Bob C., Louder, Mark K., Olia, Adam S., Zhang, Baoshan, Doria-Rose, Nicole A., Zolla-Pazner, Susan, Shapiro, Lawrence, Chuang, Gwo-Yu, Kwong, Peter D.
Published in Nature communications (09.11.2021)
Published in Nature communications (09.11.2021)
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Antibody-directed evolution reveals a mechanism for enhanced neutralization at the HIV-1 fusion peptide site
Banach, Bailey B., Pletnev, Sergei, Olia, Adam S., Xu, Kai, Zhang, Baoshan, Rawi, Reda, Bylund, Tatsiana, Doria-Rose, Nicole A., Nguyen, Thuy Duong, Fahad, Ahmed S., Lee, Myungjin, Lin, Bob C., Liu, Tracy, Louder, Mark K., Madan, Bharat, McKee, Krisha, O’Dell, Sijy, Sastry, Mallika, Schön, Arne, Bui, Natalie, Shen, Chen-Hsiang, Wolfe, Jacy R., Chuang, Gwo-Yu, Mascola, John R., Kwong, Peter D., DeKosky, Brandon J.
Published in Nature communications (21.11.2023)
Published in Nature communications (21.11.2023)
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Tyrosine O-sulfation proteoforms affect HIV-1 monoclonal antibody potency
Cai, Cindy X., Doria-Rose, Nicole A., Schneck, Nicole A., Ivleva, Vera B., Tippett, Brad, Shadrick, William R., O’Connell, Sarah, Cooper, Jonathan W., Schneiderman, Zachary, Zhang, Baoshan, Gowetski, Daniel B., Blackstock, Daniel, Demirji, Jacob, Lin, Bob C., Gorman, Jason, Liu, Tracy, Li, Yile, McDermott, Adrian B., Kwong, Peter D., Carlton, Kevin, Gall, Jason G., Lei, Q. Paula
Published in Scientific reports (19.05.2022)
Published in Scientific reports (19.05.2022)
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Engineering of HIV-1 neutralizing antibody CAP256V2LS for manufacturability and improved half life
Zhang, Baoshan, Gollapudi, Deepika, Gorman, Jason, O’Dell, Sijy, Damron, Leland F., McKee, Krisha, Asokan, Mangaiarkarasi, Yang, Eun Sung, Pegu, Amarendra, Lin, Bob C., Chao, Cara W., Chen, Xuejun, Gama, Lucio, Ivleva, Vera B., Law, William H., Liu, Cuiping, Louder, Mark K., Schmidt, Stephen D., Shen, Chen-Hsiang, Shi, Wei, Stein, Judith A., Seaman, Michael S., McDermott, Adrian B., Carlton, Kevin, Mascola, John R., Kwong, Peter D., Lei, Q. Paula, Doria-Rose, Nicole A.
Published in Scientific reports (25.10.2022)
Published in Scientific reports (25.10.2022)
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A matrix of structure-based designs yields improved VRC01-class antibodies for HIV-1 therapy and prevention
Kwon, Young D, Asokan, Mangaiarkarasi, Gorman, Jason, Zhang, Baoshan, Liu, Qingbo, Louder, Mark K, Lin, Bob C, McKee, Krisha, Pegu, Amarendra, Verardi, Raffaello, Yang, Eun Sung, Program, Vrc Production, Carlton, Kevin, Doria-Rose, Nicole A, Lusso, Paolo, Mascola, John R, Kwong, Peter D
Published in mAbs (01.01.2021)
Published in mAbs (01.01.2021)
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Improved pharmacokinetics of HIV-neutralizing VRC01-class antibodies achieved by reduction of net positive charge on variable domain
Kwon, Young D, Pegu, Amarendra, Yang, Eun Sung, Zhang, Baoshan, Bender, Michael F, Asokan, Mangaiarkarasi, Liu, Qingbo, McKee, Krisha, Lin, Bob C, Liu, Tracy, Louder, Mark K, Rawi, Reda, Reveiz, Mateo, Schaub, Andrew J, Shen, Chen-Hsiang, Doria-Rose, Nicole A, Lusso, Paolo, Mascola, John R, Kwong, Peter D
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Published in mAbs (2023)
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Stochastic Interventional Vaccine Efficacy and Principal Surrogate Analyses of Antibody Markers as Correlates of Protection against Symptomatic COVID-19 in the COVE mRNA-1273 Trial
Huang, Ying, Hejazi, Nima S, Blette, Bryan, Carpp, Lindsay N, Benkeser, David, Montefiori, David C, McDermott, Adrian B, Fong, Youyi, Janes, Holly E, Deng, Weiping, Zhou, Honghong, Houchens, Christopher R, Martins, Karen, Jayashankar, Lakshmi, Flach, Britta, Lin, Bob C, O'Connell, Sarah, McDanal, Charlene, Eaton, Amanda, Sarzotti-Kelsoe, Marcella, Lu, Yiwen, Yu, Chenchen, Kenny, Avi, Carone, Marco, Huynh, Chuong, Miller, Jacqueline, El Sahly, Hana M, Baden, Lindsey R, Jackson, Lisa A, Campbell, Thomas B, Clark, Jesse, Andrasik, Michele P, Kublin, James G, Corey, Lawrence, Neuzil, Kathleen M, Pajon, Rolando, Follmann, Dean, Donis, Ruben O, Koup, Richard A, Gilbert, Peter B, On Behalf Of The Immune Assays, Moderna Inc, Coronavirus Vaccine Prevention Network CoVPN/Coronavirus Efficacy Cove, United States Government Usg/CoVPN Biostatistics Teams
Published in Viruses (29.09.2023)
Published in Viruses (29.09.2023)
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Structural basis of glycan276-dependent recognition by HIV-1 broadly neutralizing antibodies
Cottrell, Christopher A., Manne, Kartik, Kong, Rui, Wang, Shuishu, Zhou, Tongqing, Chuang, Gwo-Yu, Edwards, Robert J., Henderson, Rory, Janowska, Katarzyna, Kopp, Megan, Lin, Bob C., Louder, Mark K., Olia, Adam S., Rawi, Reda, Shen, Chen-Hsiang, Taft, Justin D., Torres, Jonathan L., Wu, Nelson R., Zhang, Baoshan, Doria-Rose, Nicole A., Cohen, Myron S., Haynes, Barton F., Shapiro, Lawrence, Ward, Andrew B., Acharya, Priyamvada, Mascola, John R., Kwong, Peter D.
Published in Cell reports (Cambridge) (02.11.2021)
Published in Cell reports (Cambridge) (02.11.2021)
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Ultrapotent Broadly Neutralizing Human‐llama Bispecific Antibodies against HIV‐1
Xu, Jianliang, Zhou, Tongqing, McKee, Krisha, Zhang, Baoshan, Liu, Cuiping, Nazzari, Alexandra F., Pegu, Amarendra, Shen, Chen‐Hsiang, Becker, Jordan E., Bender, Michael F., Chan, Payton, Changela, Anita, Chaudhary, Ridhi, Chen, Xuejun, Einav, Tal, Kwon, Young Do, Lin, Bob C., Louder, Mark K., Merriam, Jonah S., Morano, Nicholas C., O'Dell, Sijy, Olia, Adam S., Rawi, Reda, Roark, Ryan S., Stephens, Tyler, Teng, I‐Ting, Tourtellott‐Fogt, Emily, Wang, Shuishu, Yang, Eun Sung, Shapiro, Lawrence, Tsybovsky, Yaroslav, Doria‐Rose, Nicole A., Casellas, Rafael, Kwong, Peter D.
Published in Advanced science (01.07.2024)
Published in Advanced science (01.07.2024)
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Removal of variable domain N -linked glycosylation as a means to improve the homogeneity of HIV-1 broadly neutralizing antibodies
Chuang, Gwo-Yu, Asokan, Mangaiarkarasi, Ivleva, Vera B, Pegu, Amarendra, Yang, Eun Sung, Zhang, Baoshan, Chaudhuri, Rajoshi, Geng, Hui, Lin, Bob C, Louder, Mark K, McKee, Krisha, O'Dell, Sijy, Wang, Hairong, Zhou, Tongqing, Doria-Rose, Nicole A, Kueltzo, Lisa A, Lei, Q Paula, Mascola, John R, Kwong, Peter D
Published in mAbs (01.01.2020)
Published in mAbs (01.01.2020)
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Durability of Responses after SARS-CoV-2 mRNA-1273 Vaccination
Widge, Alicia T, Rouphael, Nadine G, Jackson, Lisa A, Anderson, Evan J, Roberts, Paul C, Makhene, Mamodikoe, Chappell, James D, Denison, Mark R, Stevens, Laura J, Pruijssers, Andrea J, McDermott, Adrian B, Flach, Britta, Lin, Bob C, Doria-Rose, Nicole A, O’Dell, Sijy, Schmidt, Stephen D, Neuzil, Kathleen M, Bennett, Hamilton, Leav, Brett, Makowski, Mat, Albert, Jim, Cross, Kaitlyn, Edara, Venkata-Viswanadh, Floyd, Katharine, Suthar, Mehul S, Buchanan, Wendy, Luke, Catherine J, Ledgerwood, Julie E, Mascola, John R, Graham, Barney S, Beigel, John H
Published in New England Journal of Medicine (07.01.2021)
Published in New England Journal of Medicine (07.01.2021)
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Safety and Immunogenicity of SARS-CoV-2 mRNA-1273 Vaccine in Older Adults
Anderson, Evan J, Rouphael, Nadine G, Widge, Alicia T, Jackson, Lisa A, Roberts, Paul C, Makhene, Mamodikoe, Chappell, James D, Denison, Mark R, Stevens, Laura J, Pruijssers, Andrea J, McDermott, Adrian B, Flach, Britta, Lin, Bob C, Doria-Rose, Nicole A, O’Dell, Sijy, Schmidt, Stephen D, Corbett, Kizzmekia S, Swanson, Phillip A, Padilla, Marcelino, Neuzil, Kathy M, Bennett, Hamilton, Leav, Brett, Makowski, Mat, Albert, Jim, Cross, Kaitlyn, Edara, Venkata Viswanadh, Floyd, Katharine, Suthar, Mehul S, Martinez, David R, Baric, Ralph, Buchanan, Wendy, Luke, Catherine J, Phadke, Varun K, Rostad, Christina A, Ledgerwood, Julie E, Graham, Barney S, Beigel, John H
Published in New England Journal of Medicine (17.12.2020)
Published in New England Journal of Medicine (17.12.2020)
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Respiratory Syncytial Virus (RSV) Neutralizing Antibodies at Birth Predict Protection from RSV Illness in Infants in the First 3 Months of Life
Buchwald, Andrea G, Graham, Barney S, Traore, Awa, Haidara, Fadima Cheick, Chen, Man, Morabito, Kaitlyn, Lin, Bob C, Sow, Samba O, Levine, Myron M, Pasetti, Marcela F, Tapia, Milagritos D
Published in Clinical infectious diseases (06.12.2021)
Published in Clinical infectious diseases (06.12.2021)
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Interval between prior SARS-CoV-2 infection and booster vaccination impacts magnitude and quality of antibody and B cell responses
Buckner, Clarisa M., Kardava, Lela, El Merhebi, Omar, Narpala, Sandeep R., Serebryannyy, Leonid, Lin, Bob C., Wang, Wei, Zhang, Xiaozhen, Lopes de Assis, Felipe, Kelly, Sophie E.M., Teng, I-Ting, McCormack, Genevieve E., Praiss, Lauren H., Seamon, Catherine A., Rai, M. Ali, Kalish, Heather, Kwong, Peter D., Proschan, Michael A., McDermott, Adrian B., Fauci, Anthony S., Chun, Tae-Wook, Moir, Susan
Published in Cell (10.11.2022)
Published in Cell (10.11.2022)
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A prefusion-stabilized RSV F subunit vaccine elicits B cell responses with greater breadth and potency than a postfusion F vaccine
Chang, Lauren A, Phung, Emily, Crank, Michelle C, Morabito, Kaitlyn M, Villafana, Tonya, Dubovsky, Filip, Falloon, Judith, Esser, Mark T, Lin, Bob C, Chen, Grace L, Graham, Barney S, Ruckwardt, Tracy J
Published in Science translational medicine (21.12.2022)
Published in Science translational medicine (21.12.2022)
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Vaccination induces maturation in a mouse model of diverse unmutated VRC01-class precursors to HIV-neutralizing antibodies with >50% breadth
Chen, Xuejun, Zhou, Tongqing, Schmidt, Stephen D., Duan, Hongying, Cheng, Cheng, Chuang, Gwo-Yu, Gu, Ying, Louder, Mark K., Lin, Bob C., Shen, Chen-Hsiang, Sheng, Zizhang, Zheng, Michelle X., Doria-Rose, Nicole A., Joyce, M. Gordon, Shapiro, Lawrence, Tian, Ming, Alt, Frederick W., Kwong, Peter D., Mascola, John R.
Published in Immunity (Cambridge, Mass.) (09.02.2021)
Published in Immunity (Cambridge, Mass.) (09.02.2021)
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