A novel RyR1-selective inhibitor prevents and rescues sudden death in mouse models of malignant hyperthermia and heat stroke
Yamazawa, Toshiko, Kobayashi, Takuya, Kurebayashi, Nagomi, Konishi, Masato, Noguchi, Satoru, Inoue, Takayoshi, Inoue, Yukiko U., Nishino, Ichizo, Mori, Shuichi, Iinuma, Hiroto, Manaka, Noriaki, Kagechika, Hiroyuki, Uryash, Arkady, Adams, Jose, Lopez, Jose R., Liu, Xiaochen, Diggle, Christine, Allen, Paul D., Kakizawa, Sho, Ikeda, Keigo, Lin, Bangzhong, Ikemi, Yui, Nunomura, Kazuto, Nakagawa, Shinsaku, Sakurai, Takashi, Murayama, Takashi
Published in Nature communications (13.07.2021)
Published in Nature communications (13.07.2021)
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Journal Article
Modulation of Ca2+ oscillation following ischemia and nicotinic acetylcholine receptors in primary cortical neurons by high-throughput analysis
Sasaki, Tsutomu, Hisada, Sunao, Kanki, Hideaki, Nunomura, Kazuto, Lin, Bangzhong, Nishiyama, Kumiko, Kawano, Tomohito, Matsumura, Shigenobu, Mochizuki, Hideki
Published in Scientific reports (12.11.2024)
Published in Scientific reports (12.11.2024)
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Journal Article
Development of a high-throughput screening system targeting the protein-protein interactions between PRL and CNNM
Funato, Yosuke, Mimura, Mai, Nunomura, Kazuto, Lin, Bangzhong, Fujii, Shintarou, Haruta, Junichi, Miki, Hiroaki
Published in Scientific reports (25.10.2024)
Published in Scientific reports (25.10.2024)
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Journal Article
Design and synthesis of pyrido[2,3-d]pyrimidine derivatives for a novel PAC1 receptor antagonist
Takasaki, Ichiro, Watanabe, Ai, Okada, Takuya, Kanayama, Daisuke, Nagashima, Ryota, Shudo, Miyu, Shimodaira, Ayaka, Nunomura, Kazuto, Lin, Bangzhong, Watanabe, Yurie, Gouda, Hiroaki, Miyata, Atsuro, Kurihara, Takashi, Toyooka, Naoki
Published in European journal of medicinal chemistry (05.03.2022)
Published in European journal of medicinal chemistry (05.03.2022)
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Journal Article
Microtubule inhibitors identified through nonbiased screening enhance DNA transfection efficiency by delaying p62‐dependent ubiquitin recruitment
Tsuchiya, Megumi, Ogawa, Hidesato, Watanabe, Kento, Koujin, Takako, Mori, Chie, Nunomura, Kazuto, Lin, Bangzhong, Tani, Akiyoshi, Hiraoka, Yasushi, Haraguchi, Tokuko
Published in Genes to cells : devoted to molecular & cellular mechanisms (01.09.2021)
Published in Genes to cells : devoted to molecular & cellular mechanisms (01.09.2021)
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Journal Article
Structural development of 1H-pyrazolo-[3,4-b]pyridine-4-carboxylic acid derivatives as human peroxisome proliferator-activated receptor alpha (PPARα)-selective agonists
Miyachi, Hiroyuki, Yuzuriha, Tomohiro, Tabata, Ryotaro, Fukuda, Syohei, Nunomura, Kazuto, Lin, Bangzhong, Kobayashi, Tadayuki, Ishimoto, Kenji, Doi, Takefumi, Tachibana, Keisuke
Published in Bioorganic & medicinal chemistry letters (15.08.2019)
Published in Bioorganic & medicinal chemistry letters (15.08.2019)
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Discovery of Benzylpiperazine Derivatives as CNS-Penetrant and Selective Histone Deacetylase 6 Inhibitors
Hashimoto, Kosuke, Ide, Soichiro, Arata, Mayumi, Nakata, Akiko, Ito, Akihiro, Ito, Takashi K., Kudo, Norio, Lin, Bangzhong, Nunomura, Kazuto, Tsuganezawa, Keiko, Yoshida, Minoru, Nagaoka, Yasuo, Sumiyoshi, Takaaki
Published in ACS medicinal chemistry letters (14.07.2022)
Published in ACS medicinal chemistry letters (14.07.2022)
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Journal Article
Opposing roles for SNAP23 in secretion in exocrine and endocrine pancreatic cells
Kunii, Masataka, Ohara-Imaizumi, Mica, Takahashi, Noriko, Kobayashi, Masaki, Kawakami, Ryosuke, Kondoh, Yasumitsu, Shimizu, Takeshi, Simizu, Siro, Lin, Bangzhong, Nunomura, Kazuto, Aoyagi, Kyota, Ohno, Mitsuyo, Ohmuraya, Masaki, Sato, Takashi, Yoshimura, Shin-Ichiro, Sato, Ken, Harada, Reiko, Kim, Yoon-Jeong, Osada, Hiroyuki, Nemoto, Tomomi, Kasai, Haruo, Kitamura, Tadahiro, Nagamatsu, Shinya, Harada, Akihiro
Published in The Journal of cell biology (10.10.2016)
Published in The Journal of cell biology (10.10.2016)
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Journal Article
Physicochemical and Biochemical Evaluation of Amorphous Solid Dispersion of Naringenin Prepared Using Hot-Melt Extrusion
Ishimoto, Kenji, Shimada, Yukiko, Ohno, Akane, Otani, Shuichi, Ago, Yukio, Maeda, Soya, Lin, Bangzhong, Nunomura, Kazuto, Hino, Nobumasa, Suzuki, Masayuki, Nakagawa, Shinsaku
Published in Frontiers in nutrition (Lausanne) (27.04.2022)
Published in Frontiers in nutrition (Lausanne) (27.04.2022)
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Celastrol suppresses humoral immune responses and autoimmunity by targeting the COMMD3/8 complex
Shirai, Taiichiro, Nakai, Akiko, Ando, Emiko, Fujimoto, Jun, Leach, Sarah, Arimori, Takao, Higo, Daisuke, van Eerden, Floris J, Tulyeu, Janyerkye, Liu, Yu-Chen, Okuzaki, Daisuke, Murayama, Masanori A, Miyata, Haruhiko, Nunomura, Kazuto, Lin, Bangzhong, Tani, Akiyoshi, Kumanogoh, Atsushi, Ikawa, Masahito, Wing, James B, Standley, Daron M, Takagi, Junichi, Suzuki, Kazuhiro
Published in Science immunology (31.03.2023)
Published in Science immunology (31.03.2023)
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Journal Article
Bayesian approach enabled objective comparison of multiple human iPSC-derived Cardiomyocytes' Proarrhythmia sensitivities
Wakatsuki, Tetsuro, Daily, Neil, Hisada, Sunao, Nunomura, Kazuto, Lin, Bangzhong, Zushida, Ko, Honda, Yayoi, Asyama, Mahoko, Takasuna, Kiyoshi
Published in Journal of pharmacological and toxicological methods (01.07.2024)
Published in Journal of pharmacological and toxicological methods (01.07.2024)
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Journal Article
Synthesis and Biological Evaluation of Simplified Ansellone Analogues with Lipophilic Side Chains as HIV Latency‐Reversing Agents
Yanagihara, Mizushi, Kishimoto, Naoki, Nakahara, Kanae, Abe, Towa, Miura, Satoshi, Lin, Bangzhong, Fumimoto, Megumi, Haruta, Junichi, Misumi, Shogo, Arisawa, Mitsuhiro, Murai, Kenichi
Published in Chemistry : a European journal (04.08.2023)
Published in Chemistry : a European journal (04.08.2023)
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Journal Article
Design and synthesis of 4-acetoxypentanamide derivatives of spliceostatin A and their biological evaluation towards prostate cancer treatment
Hirabayashi, Satoru, Tsuyuguchi, Yuko, Li, Yue, Ohta, Noriko, Yoshikawa, Yusuke, Lin, Bangzhong, Fumimoto, Megumi, Nunomura, Kazuto, Suzuki, Takeyuki, Haruta, Junichi, Nimura, Keisuke, Arisawa, Mitsuhiro
Published in Bioorganic & medicinal chemistry letters (15.07.2023)
Published in Bioorganic & medicinal chemistry letters (15.07.2023)
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Journal Article
Design and synthesis of ether derivatives of spliceostatin A and their biological evaluation towards prostate cancer treatment
Hirabayashi, Satoru, Li, Yue, Ohta, Noriko, Ishibashi, Airi, Yoshikawa, Yusuke, Lin, Bangzhong, Fumimoto, Megumi, Takehara, Tsunayoshi, Nunomura, Kazuto, Suzuki, Takeyuki, Haruta, Junichi, Nimura, Keisuke, Arisawa, Mitsuhiro
Published in Tetrahedron letters (12.01.2023)
Published in Tetrahedron letters (12.01.2023)
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Journal Article
A novel RyR1 inhibitor prevents and rescues sudden death in a mouse model of malignant hyperthermia and heat stroke
Yamazawa, Toshiko, Kobayashi, Takuya, Kurebayashi, Nagomi, Konishi, Masato, Noguchi, Satoru, Inoue, Takayoshi, Inoue, Yukiko U, Nishino, Ichizo, Mori, Shuichi, Iinuma, Hiroto, Manaka, Noriaki, Kagechika, Hiroyuki, Uryas, Arkady, Adams, Jose, Lopez, Jose R, Liu, Xiaochen, Diggle, Christine, Allen, Paul D, Kakizawa, Sho, Ikeda, Keigo, Lin, Bangzhong, Ikemi, Yui, Nunomura, Kazuto, Nakagawa, Shinsaku, Sakurai, Takashi, Murayama, Takashi
Published in bioRxiv (06.02.2021)
Published in bioRxiv (06.02.2021)
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Paper
Modulation of Ca 2+ oscillation following ischemia and nicotinic acetylcholine receptors in primary cortical neurons by high-throughput analysis
Sasaki, Tsutomu, Hisada, Sunao, Kanki, Hideaki, Nunomura, Kazuto, Lin, Bangzhong, Nishiyama, Kumiko, Kawano, Tomohito, Matsumura, Shigenobu, Mochizuki, Hideki
Published in Scientific reports (12.11.2024)
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Published in Scientific reports (12.11.2024)
Journal Article
Discovery of peroxisome proliferator–activated receptor α (PPARα) activators with a ligand-screening system using a human PPARα-expressing cell line
Tachibana, Keisuke, Yuzuriha, Tomohiro, Tabata, Ryotaro, Fukuda, Syohei, Maegawa, Takashi, Takahashi, Rika, Tanimoto, Keiichi, Tsujino, Hirofumi, Nunomura, Kazuto, Lin, Bangzhong, Matsuura, Yoshiharu, Tanaka, Toshiya, Hamakubo, Takao, Sakai, Juro, Kodama, Tatsuhiko, Kobayashi, Tadayuki, Ishimoto, Kenji, Miyachi, Hiroyuki, Doi, Takefumi
Published in The Journal of biological chemistry (29.06.2018)
Published in The Journal of biological chemistry (29.06.2018)
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