Plasma and breast milk pharmacokinetics of tenofovir alafenamide in mothers with chronic hepatitis B infection
Kayes, Tahrima, Crane, Harry, Symonds, Allison, Dumond, Julie, Cottrell, Mackenzie, Di Girolamo, Julia, Manandhar, Sicha, Lim, Tien Huey, Gane, Edward, Kashuba, Angela, Levy, Miriam T.
Published in Alimentary pharmacology & therapeutics (01.08.2022)
Published in Alimentary pharmacology & therapeutics (01.08.2022)
Get full text
Journal Article
Clinical Study of Single‐Stranded Oligonucleotide RO7062931 in Healthy Volunteers and Patients With Chronic Hepatitis B
Gane, Edward, Yuen, Man‐Fung, Kim, Dong Joon, Chan, Henry Lik‐Yuen, Surujbally, Bernadette, Pavlovic, Vedran, Das, Sudip, Triyatni, Miriam, Kazma, Remi, Grippo, Joseph F., Buatois, Simon, Lemenuel‐Diot, Annabelle, Krippendorff, Ben‐Fillippo, Mueller, Henrik, Zhang, Yuchen, Kim, Hyung Joon, Leerapun, Apinya, Lim, Tien Huey, Lim, Young‐Suk, Tanwandee, Tawesak, Kim, Won, Cheng, Wendy, Hu, Tsung‐Hui, Wat, Cynthia
Published in Hepatology (Baltimore, Md.) (01.10.2021)
Published in Hepatology (Baltimore, Md.) (01.10.2021)
Get full text
Journal Article
Therapeutic vaccine BRII-179 restores HBV-specific immune responses in patients with chronic HBV in a phase Ib/IIa study
Ma, Haiyan, Lim, Tien Huey, Leerapun, Apinya, Weltman, Martin, Jia, Jidong, Lim, Young-suk, Tangkijvanich, Pisit, Sukeepaisarnjaroen, Wattana, Ji, Yun, Le Bert, Nina, Li, Dong, Zhang, Yao, Hamatake, Robert, Tan, Nicole, Li, Chunming, Strasser, Simone I., Ding, Huiguo, Yoon, Jung-Hwan, Stace, Nigel H., Ahmed, Tanvir, Anderson, Dave E., Yan, Li, Bertoletti, Antonio, Zhu, Qing, Yuen, Man-Fung
Published in JHEP reports (01.12.2021)
Published in JHEP reports (01.12.2021)
Get full text
Journal Article
Efficacy, safety, and pharmacokinetics of capsid assembly modulator linvencorvir plus standard of care in chronic hepatitis B patients
Hou, Jinlin, Gane, Edward, Balabanska, Rozalina, Zhang, Wenhong, Zhang, Jiming, Lim, Tien Huey, Xie, Qing, Yeh, Chau-Ting, Yang, Sheng-Shun, Liang, Xieer, Komolmit, Piyawat, Leerapun, Apinya, Xue, Zenghui, Chen, Ethan, Zhang, Yuchen, Xie, Qiaoqiao, Chang, Ting-Tsung, Hu, Tsung-Hui, Lim, Seng Gee, Chuang, Wan-Long, Leggett, Barbara, Bo, Qingyan, Zhou, Xue, Triyatni, Miriam, Zhang, Wen, Yuen, Man-Fung
Published in Clinical and molecular hepatology (01.04.2024)
Published in Clinical and molecular hepatology (01.04.2024)
Get full text
Journal Article
Combination treatments including the small-interfering RNA JNJ-3989 induce rapid and sometimes prolonged viral responses in patients with CHB
Yuen, Man-Fung, Locarnini, Stephen, Lim, Tien Huey, Strasser, Simone I., Sievert, William, Cheng, Wendy, Thompson, Alex J., Given, Bruce D., Schluep, Thomas, Hamilton, James, Biermer, Michael, Kalmeijer, Ronald, Beumont, Maria, Lenz, Oliver, De Ridder, Filip, Cloherty, Gavin, Ka-Ho Wong, Danny, Schwabe, Christian, Jackson, Kathy, Lai, Ching Lung, Gish, Robert G., Gane, Edward
Published in Journal of hepatology (01.11.2022)
Published in Journal of hepatology (01.11.2022)
Get full text
Journal Article
Safety and efficacy of VIR-2218 with or without pegylated interferon alfa in virally-suppressed participants with chronic hepatitis B virus infection: post-treatment follow-up
Yuen, Man-Fung, Lim, Young-Suk, yoon, Ki Tae, Lim, Tien Huey, Heo, Jeong, Tangkijvanich, Pisit, Tak, Won Young, Thanawala, Vaidehi, Cloutier, Daniel, Mao, Shenghua, Arizpe, Andre, Cathcart, Andrea, Gupta, Sneha V., Hwang, Carey, Gane, Edward J.
Published in Journal of hepatology (01.06.2023)
Published in Journal of hepatology (01.06.2023)
Get full text
Journal Article
LBO-02 - Safety and efficacy of VIR-2218 with or without pegylated interferon alfa in virally-suppressed participants with chronic hepatitis B virus infection: post-treatment follow-up
Yuen, Man-Fung, Lim, Young-Suk, yoon, Ki Tae, Lim, Tien Huey, Heo, Jeong, Tangkijvanich, Pisit, Tak, Won Young, Thanawala, Vaidehi, Cloutier, Daniel, Mao, Shenghua, Arizpe, Andre, Cathcart, Andrea, Gupta, Sneha V., Hwang, Carey, Gane, Edward J.
Published in Journal of hepatology (01.06.2023)
Published in Journal of hepatology (01.06.2023)
Get full text
Journal Article
Safety and antiviral activity of short-duration combinations of the investigational small interfering ribonucleic acid VIR-2218 with the neutralizing, vaccinal monoclonal antibody VIR-3434: post-treatment follow-up from the Phase 2 MARCH trial
Gane, Edward J., Jucov, Alina, Dobryanksa, Marta, yoon, Ki Tae, Lim, Tien Huey, Arizpe, Andre, Cloutier, Daniel, Chattergoon, Michael, Mao, Shenghua, Gupta, Sneha V., Camus, Gregory, Hwang, Carey, Lim, Young-Suk
Published in Journal of hepatology (01.06.2023)
Published in Journal of hepatology (01.06.2023)
Get full text
Journal Article
OS-031 - Safety and antiviral activity of short-duration combinations of the investigational small interfering ribonucleic acid VIR-2218 with the neutralizing, vaccinal monoclonal antibody VIR-3434: post-treatment follow-up from the Phase 2 MARCH trial
Gane, Edward J., Jucov, Alina, Dobryanksa, Marta, yoon, Ki Tae, Lim, Tien Huey, Arizpe, Andre, Cloutier, Daniel, Chattergoon, Michael, Mao, Shenghua, Gupta, Sneha V., Camus, Gregory, Hwang, Carey, Lim, Young-Suk
Published in Journal of hepatology (01.06.2023)
Published in Journal of hepatology (01.06.2023)
Get full text
Journal Article
First-in-human randomized study of RNAi therapeutic RG6346 for chronic hepatitis B virus infection
Gane, Edward J., Kim, Won, Lim, Tien Huey, Tangkijvanich, Pisit, Yoon, Jung-Hwan, Sievert, William, Sukeepaisarnjaroen, Wattana, Thompson, Alexander J., Pavlovic, Vedran, Surujbally, Bernadette, Wat, Cynthia, Brown, Bob D., Achneck, Hardean E., Yuen, Man-Fung
Published in Journal of hepatology (01.11.2023)
Published in Journal of hepatology (01.11.2023)
Get full text
Journal Article
Viral nucleic acids suppression activity of RO7049389 plus NUC with/without Peg-IFN in virologically-suppressed and naive chronic hepatitis B patients: 48-week treatment and post-treatment follow-up
Yuen, Man-Fung, Balabanska, Rozalina, Hou, Jinlin, Gane, Edward J, Lim, Tien Huey, Zhang, WenHong, Xie, Qing, Komolmit, Piyawat, Leerapun, Apinya, Yang, Sheng-Shun, Yeh, Chau-Ting, Zhang, Wen, Zhou, Xue, Xue, Zenghui, Triyatni, Miriam, Chen, Ethan, Li, Rui, Bo, Qingyan
Published in Journal of hepatology (01.07.2022)
Published in Journal of hepatology (01.07.2022)
Get full text
Journal Article
Hepatitis B virus antigen reduction effect of RO7049389 plus NUC with/without Peg-IFN in chronic hepatitis B patients
Hou, Jinlin, Gane, Edward J, Zhang, Wenhong, Zhang, Jiming, Yuen, Man-Fung, Lim, Tien Huey, Balabanska, Rozalina, Xie, Qing, Komolmit, Piyawat, Liang, Xieer, Zhang, Wen, Zhou, Xue, Xue, Zenghui, Triyatni, Miriam, Chen, Ethan, Zhang, Yuchen, Bo, Qingyan
Published in Journal of hepatology (01.07.2022)
Published in Journal of hepatology (01.07.2022)
Get full text
Journal Article
Preliminary safety and antiviral activity of VIR-2218, an X-targeting HBV RNAi therapeutic, in chronic hepatitis B patients
Gane, Edward, Lim, Young-Suk, Tangkijvanich, Pisit, O’Beirne, James, Lim, Tien Huey, Bakardjiev, Anna, Ding, Xiao, Connolly, Lynn, Huang, Stephen, Kim, Jae, Pang, Phil, Yuen, Man-Fung
Published in Journal of hepatology (01.08.2020)
Published in Journal of hepatology (01.08.2020)
Get full text
Journal Article
AS068 - Preliminary safety and antiviral activity of VIR-2218, an X-targeting HBV RNAi therapeutic, in chronic hepatitis B patients
Gane, Edward, Lim, Young-Suk, Tangkijvanich, Pisit, O’Beirne, James, Lim, Tien Huey, Bakardjiev, Anna, Ding, Xiao, Connolly, Lynn, Huang, Stephen, Kim, Jae, Pang, Phil, Yuen, Man-Fung
Published in Journal of hepatology (01.08.2020)
Published in Journal of hepatology (01.08.2020)
Get full text
Journal Article
AS069 - RO7062931 antisense oligonucleotide phase 1 study demonstrates target engagement in patients with chronic hepatitis B on established nucleos(t)ide therapy
Yuen, Man-Fung, Gane, Edward, Kim, Dong Joon, Chan, Henry, Surujbally, Bernadette, Pavlovic, Vedran, Triyatni, Miriam, Grippo, Joseph, Kim, Hyung Joon, Leerapun, Apinya, Lim, Tien Huey, Lim, Young-Suk, Tanwandee, Tawesak, Kim, Won, Cheng, Wendy, Hu, Tsung-Hui, Wat, Cynthia
Published in Journal of hepatology (01.08.2020)
Published in Journal of hepatology (01.08.2020)
Get full text
Journal Article
RO7062931 antisense oligonucleotide phase 1 study demonstrates target engagement in patients with chronic hepatitis B on established nucleos(t)ide therapy
Yuen, Man-Fung, Gane, Edward, Kim, Dong Joon, Chan, Henry, Surujbally, Bernadette, Pavlovic, Vedran, Triyatni, Miriam, Grippo, Joseph, Kim, Hyung Joon, Leerapun, Apinya, Lim, Tien Huey, Lim, Young-Suk, Tanwandee, Tawesak, Kim, Won, Cheng, Wendy, Hu, Tsung-Hui, Wat, Cynthia
Published in Journal of hepatology (01.08.2020)
Published in Journal of hepatology (01.08.2020)
Get full text
Journal Article
Short-term treatment with RNA interference therapy, JNJ-3989, results in sustained hepatitis B surface antigen supression in patients with chronic hepatitis B receiving nucleos(t)ide analogue treatment
Gane, Edward, Locarnini, Stephen, Lim, Tien Huey, Strasser, Simone, Sievert, William, Cheng, Wendy, Thompson, Alexander, Given, Bruce, Schluep, Thomas, Hamilton, James, Biermer, Michael, Kalmeijer, Ronald, Beumont-Mauviel, Maria, Lenz, Oliver, Cloherty, Gavin, Wong, Danny Ka-Ho, Schwabe, Christian, Jackson, Kathy, Ferrari, Carlo, Lai, Ching Lung, Gish, Robert G., Yuen, Man-Fung
Published in Journal of hepatology (01.08.2020)
Published in Journal of hepatology (01.08.2020)
Get full text
Journal Article
GS10 - Short-term treatment with RNA interference therapy, JNJ-3989, results in sustained hepatitis B surface antigen supression in patients with chronic hepatitis B receiving nucleos(t)ide analogue treatment
Gane, Edward, Locarnini, Stephen, Lim, Tien Huey, Strasser, Simone, Sievert, William, Cheng, Wendy, Thompson, Alexander, Given, Bruce, Schluep, Thomas, Hamilton, James, Biermer, Michael, Kalmeijer, Ronald, Beumont-Mauviel, Maria, Lenz, Oliver, Cloherty, Gavin, Wong, Danny Ka-Ho, Schwabe, Christian, Jackson, Kathy, Ferrari, Carlo, Lai, Ching Lung, Gish, Robert G., Yuen, Man-Fung
Published in Journal of hepatology (01.08.2020)
Published in Journal of hepatology (01.08.2020)
Get full text
Journal Article