In vivo lentiviral vector gene therapy to cure hereditary tyrosinemia type 1 and prevent development of precancerous and cancerous lesions
Nicolas, Clara T., VanLith, Caitlin J., Hickey, Raymond D., Du, Zeji, Hillin, Lori G., Guthman, Rebekah M., Cao, William J., Haugo, Benjamin, Lillegard, Annika, Roy, Diya, Bhagwate, Aditya, O’Brien, Daniel, Kocher, Jean-Pierre, Kaiser, Robert A., Russell, Stephen J., Lillegard, Joseph B.
Published in Nature communications (25.08.2022)
Published in Nature communications (25.08.2022)
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Fetoscopy-Assisted Percutaneous Decompression of the Distal Trachea and Lungs Reverses Hydrops Fetalis and Fetal Distress in a Fetus with Laryngeal Atresia
Nicolas, Clara T, Lynch-Salamon, David, Bendel-Stenzel, Ellen, Tibesar, Robert, Luks, Francois, Eyerly-Webb, Stephanie, Lillegard, Joseph B
Published in Fetal diagnosis and therapy (01.07.2019)
Published in Fetal diagnosis and therapy (01.07.2019)
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Hepatocyte spheroids as an alternative to single cells for transplantation after ex vivo gene therapy in mice and pig models
Nicolas, Clara T., Hickey, Raymond D., Allen, Kari L., Du, Zeji, Guthman, Rebekah M., Kaiser, Robert A., Amiot, Bruce, Bansal, Aditya, Pandey, Mukesh K., Suksanpaisan, Lukkana, DeGrado, Timothy R, Nyberg, Scott L., Lillegard, Joseph B.
Published in Surgery (01.09.2018)
Published in Surgery (01.09.2018)
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Role of Kupffer cells and toll-like receptor 4 in acetaminophen-induced acute liver failure
Fisher, James E., MD, McKenzie, Travis J., MD, Lillegard, Joseph B., MD, PhD, Yu, Yue, MD, PhD, Juskewitch, Justin E, Nedredal, Geir I., MD, PhD, Brunn, Gregory J., PhD, Yi, Eunhee S., MD, Malhi, Harmeet, MBBS, Smyrk, Thomas C., MD, Nyberg, Scott L., MD, PhD
Published in The Journal of surgical research (01.03.2013)
Published in The Journal of surgical research (01.03.2013)
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Development of a porcine model of phenylketonuria with a humanized R408W mutation for gene editing
Kaiser, Robert A, Carlson, Daniel F, Allen, Kari L, Webster, Dennis A, VanLith, Caitlin J, Nicolas, Clara T, Hillin, Lori G, Yu, Yue, Kaiser, Catherine W, Wahoff, William R, Hickey, Raymond D, Watson, Adrienne L, Winn, Shelley R, Thöny, Beat, Kern, Douglas R, Harding, Cary O, Lillegard, Joseph B
Published in PloS one (25.01.2021)
Published in PloS one (25.01.2021)
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Journal Article
Autologous Gene and Cell Therapy Provides Safe and Long-Term Curative Therapy in A Large Pig Model of Hereditary Tyrosinemia Type 1
Hickey, Raymond D., Nicolas, Clara T., Allen, Kari, Mao, Shennen, Elgilani, Faysal, Glorioso, Jaime, Amiot, Bruce, VanLith, Caitlin, Guthman, Rebekah, Du, Zeji, Chen, Harvey, Harding, Cary O., Kaiser, Robert A., Nyberg, Scott L., Lillegard, Joseph B.
Published in Cell transplantation (01.01.2019)
Published in Cell transplantation (01.01.2019)
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Journal Article
Fumarylacetoacetate hydrolase deficient pigs are a novel large animal model of metabolic liver disease
Hickey, Raymond D., Mao, Shennen A., Glorioso, Jaime, Lillegard, Joseph B., Fisher, James E., Amiot, Bruce, Rinaldo, Piero, Harding, Cary O., Marler, Ronald, Finegold, Milton J., Grompe, Markus, Nyberg, Scott L.
Published in Stem cell research (01.07.2014)
Published in Stem cell research (01.07.2014)
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Journal Article
Ex Vivo Cell Therapy by Ectopic Hepatocyte Transplantation Treats the Porcine Tyrosinemia Model of Acute Liver Failure
Nicolas, Clara T., Kaiser, Robert A., Hickey, Raymond D., Allen, Kari L., Du, Zeji, VanLith, Caitlin J., Guthman, Rebekah M., Amiot, Bruce, Suksanpaisan, Lukkana, Han, Bing, Francipane, Maria Giovanna, Cheikhi, Amin, Jiang, Huailei, Bansal, Aditya, Pandey, Mukesh K., Garg, Ishan, Lowe, Val, Bhagwate, Aditya, O’Brien, Daniel, Kocher, Jean-Pierre A., DeGrado, Timothy R., Nyberg, Scott L., Lagasse, Eric, Lillegard, Joseph B.
Published in Molecular therapy. Methods & clinical development (11.09.2020)
Published in Molecular therapy. Methods & clinical development (11.09.2020)
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Journal Article
Serum-Free Medium and Mesenchymal Stromal Cells Enhance Functionality and Stabilize Integrity of Rat Hepatocyte Spheroids
Bao, Ji, Fisher, James E., Lillegard, Joseph B., Wang, William, Amiot, Bruce, Yu, Yue, Dietz, Allan B., Nahmias, Yaakov, Nyberg, Scott L.
Published in Cell transplantation (01.02.2013)
Published in Cell transplantation (01.02.2013)
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Normal atmospheric oxygen tension and the use of antioxidants improve hepatocyte spheroid viability and function
Lillegard, Joseph B., Fisher, James E., Nedredal, Geir, Luebke-Wheeler, Jennifer, Bao, Ji, Wang, William, Amoit, Bruce, Nyberg, Scott L.
Published in Journal of cellular physiology (01.11.2011)
Published in Journal of cellular physiology (01.11.2011)
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Optimization of mass transfer for toxin removal and immunoprotection of hepatocytes in a bioartificial liver
Nedredal, Geir I, Amiot, Bruce P, Nyberg, Peter, Luebke-Wheeler, Jennifer, Lillegard, Joseph B, McKenzie, Travis J, Nyberg, Scott L
Published in Biotechnology and bioengineering (01.12.2009)
Published in Biotechnology and bioengineering (01.12.2009)
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Hepatic Resection for the Carcinoid Syndrome in Patients with Severe Carcinoid Heart Disease: Does Valve Replacement Permit Safe Hepatic Resection?
Lillegard, Joseph B., MD, PhD, Fisher, James E., MD, Mckenzie, Travis J., MD, Que, Florencia G., MD, FACS, Farnell, Michael B., MD, FACS, Kendrick, Michael L., MD, FACS, Donohue, John H., MD, FACS, Reid-Lombardo, Kaye, MD, FACS, Schaff, Hartzell V., MD, FACS, Connolly, Heidi M., MD, Nagorney, David M., MD, FACS
Published in Journal of the American College of Surgeons (01.07.2011)
Published in Journal of the American College of Surgeons (01.07.2011)
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Journal Article
Conference Proceeding
Curative Ex Vivo Hepatocyte-Directed Gene Editing in a Mouse Model of Hereditary Tyrosinemia Type 1
VanLith, Caitlin, Guthman, Rebekah, Nicolas, Clara T, Allen, Kari, Du, Zeji, Joo, Dong Jin, Nyberg, Scott L, Lillegard, Joseph B, Hickey, Raymond D
Published in Human gene therapy (01.11.2018)
Published in Human gene therapy (01.11.2018)
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Journal Article
Aldosteronomas--state of the art
McKenzie, Travis J, Lillegard, Joseph B, Young, Jr, William F, Thompson, Geoffrey B
Published in The Surgical clinics of North America (01.10.2009)
Published in The Surgical clinics of North America (01.10.2009)
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Journal Article
Cell therapies for liver diseases
Yu, Yue, Fisher, James E., Lillegard, Joseph B., Rodysill, Brian, Amiot, Bruce, Nyberg, Scott L.
Published in Liver transplantation (01.01.2012)
Published in Liver transplantation (01.01.2012)
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Continuous Fetal Cardiac Monitoring During Fetoscopic Myelomeningocele Repair and Relationship to Spectral Doppler Changes
Eyerly-Webb, Stephanie A, Howley, Lisa, Brock, Clifton O, Lillegard, Joseph B, Fisher, James, Reynolds, Benjamin, Barthel, Emily F, Dion, Eric, Snowise, Saul
Published in Fetal diagnosis and therapy (01.08.2024)
Published in Fetal diagnosis and therapy (01.08.2024)
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Journal Article
Activation of homology-directed DNA repair plays key role in CRISPR-mediated genome correction
Mondal, Gourish, VanLith, Caitlin J., Nicolas, Clara T., Thompson, Whitney S., Cao, William S., Hillin, Lori, Haugo, Benjamin J., Brien, Daniel R. O’, Kocher, Jean-Pierre, Kaiser, Robert A., Lillegard, Joseph B.
Published in Gene therapy (01.04.2023)
Published in Gene therapy (01.04.2023)
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