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Glioproliferative Lesion of the Spinal Cord as a Complication of “Stem-Cell Tourism”
Berkowitz, Aaron L, Miller, Michael B, Mir, Saad A, Cagney, Daniel, Chavakula, Vamsidhar, Guleria, Indira, Aizer, Ayal, Ligon, Keith L, Chi, John H
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Orally administered colony stimulating factor 1 receptor inhibitor PLX3397 in recurrent glioblastoma: an Ivy Foundation Early Phase Clinical Trials Consortium phase II study
Butowski, Nicholas, Colman, Howard, De Groot, John F, Omuro, Antonio M, Nayak, Lakshmi, Wen, Patrick Y, Cloughesy, Timothy F, Marimuthu, Adhirai, Haidar, Sam, Perry, Arie, Huse, Jason, Phillips, Joanna, West, Brian L, Nolop, Keith B, Hsu, Henry H, Ligon, Keith L, Molinaro, Annette M, Prados, Michael
Published in Neuro-oncology (Charlottesville, Va.) (01.04.2016)
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Somatic Activation of AKT3 Causes Hemispheric Developmental Brain Malformations
Poduri, Annapurna, Evrony, Gilad D., Cai, Xuyu, Elhosary, Princess Christina, Beroukhim, Rameen, Lehtinen, Maria K., Hills, L. Benjamin, Heinzen, Erin L., Hill, Anthony, Hill, R. Sean, Barry, Brenda J., Bourgeois, Blaise F.D., Riviello, James J., Barkovich, A. James, Black, Peter M., Ligon, Keith L., Walsh, Christopher A.
Published in Neuron (Cambridge, Mass.) (12.04.2012)
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Genomic sequencing of meningiomas identifies oncogenic SMO and AKT1 mutations
Brastianos, Priscilla K, Horowitz, Peleg M, Santagata, Sandro, Jones, Robert T, McKenna, Aaron, Getz, Gad, Ligon, Keith L, Palescandolo, Emanuele, Van Hummelen, Paul, Ducar, Matthew D, Raza, Alina, Sunkavalli, Ashwini, Macconaill, Laura E, Stemmer-Rachamimov, Anat O, Louis, David N, Hahn, William C, Dunn, Ian F, Beroukhim, Rameen
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Published in Nature genetics (01.03.2013)
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Dynamic BH3 profiling identifies pro-apoptotic drug combinations for the treatment of malignant pleural mesothelioma
Potter, Danielle S, Du, Ruochen, Bohl, Stephan R, Chow, Kin-Hoe, Ligon, Keith L, Bueno, Raphael, Letai, Anthony
Published in Nature communications (20.05.2023)
Published in Nature communications (20.05.2023)
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Transformation by the (R)―enantiomer of 2-hydroxyglutarate linked to EGLN activation
KOIVUNEN, Peppi, LEE, Sungwoo, TRAVINS, Jeremy, WEISS, Samuel, LOOPER, Ryan, LIGON, Keith L, VERHAAK, Roel G. W, HAI YAN, KAELIN, William G, DUNCAN, Christopher G, LOPEZ, Giselle, GANG LU, RAMKISSOON, Shakti, LOSMAN, Julie A, JOENSUU, Paivi, BERGMANN, Ulrich, GROSS, Stefan
Published in Nature (London) (22.03.2012)
Published in Nature (London) (22.03.2012)
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Delivery of Functional Anti-miR-9 by Mesenchymal Stem Cell–derived Exosomes to Glioblastoma Multiforme Cells Conferred Chemosensitivity
Munoz, Jessian L, Bliss, Sarah A, Greco, Steven J, Ramkissoon, Shakti H, Ligon, Keith L, Rameshwar, Pranela
Published in Molecular therapy. Nucleic acids (01.10.2013)
Published in Molecular therapy. Nucleic acids (01.10.2013)
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Spatial and temporal homogeneity of driver mutations in diffuse intrinsic pontine glioma
Nikbakht, Hamid, Panditharatna, Eshini, Mikael, Leonie G, Li, Rui, Gayden, Tenzin, Osmond, Matthew, Ho, Cheng-Ying, Kambhampati, Madhuri, Hwang, Eugene I, Faury, Damien, Siu, Alan, Papillon-Cavanagh, Simon, Bechet, Denise, Ligon, Keith L, Ellezam, Benjamin, Ingram, Wendy J, Stinson, Caedyn, Moore, Andrew S, Warren, Katherine E, Karamchandani, Jason, Packer, Roger J, Jabado, Nada, Majewski, Jacek, Nazarian, Javad
Published in Nature communications (06.04.2016)
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A molecularly integrated grade for meningioma
Driver, Joseph, Hoffman, Samantha E, Tavakol, Sherwin, Woodward, Eleanor, Maury, Eduardo A, Bhave, Varun, Greenwald, Noah F, Nassiri, Farshad, Aldape, Kenneth, Zadeh, Gelareh, Choudhury, Abrar, Vasudevan, Harish N, Magill, Stephen T, Raleigh, David R, Abedalthagafi, Malak, Aizer, Ayal A, Alexander, Brian M, Ligon, Keith L, Reardon, David A, Wen, Patrick Y, Al-Mefty, Ossama, Ligon, Azra H, Dubuc, Adrian M, Beroukhim, Rameen, Claus, Elizabeth B, Dunn, Ian F, Santagata, Sandro, Linda Bi, Wenya
Published in Neuro-oncology (Charlottesville, Va.) (04.05.2022)
Published in Neuro-oncology (Charlottesville, Va.) (04.05.2022)
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BRAF mutation and CDKN2A deletion define a clinically distinct subgroup of childhood secondary high-grade glioma
Mistry, Matthew, Zhukova, Nataliya, Merico, Daniele, Rakopoulos, Patricia, Krishnatry, Rahul, Shago, Mary, Stavropoulos, James, Alon, Noa, Pole, Jason D, Ray, Peter N, Navickiene, Vilma, Mangerel, Joshua, Remke, Marc, Buczkowicz, Pawel, Ramaswamy, Vijay, Guerreiro Stucklin, Ana, Li, Martin, Young, Edwin J, Zhang, Cindy, Castelo-Branco, Pedro, Bakry, Doua, Laughlin, Suzanne, Shlien, Adam, Chan, Jennifer, Ligon, Keith L, Rutka, James T, Dirks, Peter B, Taylor, Michael D, Greenberg, Mark, Malkin, David, Huang, Annie, Bouffet, Eric, Hawkins, Cynthia E, Tabori, Uri
Published in Journal of clinical oncology (20.03.2015)
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BRAF V600E mutations are common in pleomorphic xanthoastrocytoma: diagnostic and therapeutic implications
Dias-Santagata, Dora, Lam, Quynh, Vernovsky, Kathy, Vena, Natalie, Lennerz, Jochen K, Borger, Darrell R, Batchelor, Tracy T, Ligon, Keith L, Iafrate, A John, Ligon, Azra H, Louis, David N, Santagata, Sandro
Published in PloS one (29.03.2011)
Published in PloS one (29.03.2011)
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Ambient mass spectrometry for the intraoperative molecular diagnosis of human brain tumors
Eberlin, Livia S., Norton, Isaiah, Orringer, Daniel, Dunn, Ian F., Liu, Xiaohui, Ide, Jennifer L., Jarmusch, Alan K., Ligon, Keith L., Jolesz, Ferenc A., Golby, Alexandra J., Santagata, Sandro, Agar, Nathalie Y. R., Cooks, R. Graham
Published in Proceedings of the National Academy of Sciences - PNAS (29.01.2013)
Published in Proceedings of the National Academy of Sciences - PNAS (29.01.2013)
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Malignant astrocytic glioma: genetics, biology, and paths to treatment
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Published in Genes & development (01.11.2007)
Published in Genes & development (01.11.2007)
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Intraoperative mass spectrometry mapping of an onco-metabolite to guide brain tumor surgery
Santagata, Sandro, Eberlin, Livia S., Norton, Isaiah, Calligaris, David, Feldman, Daniel R., Ide, Jennifer L., Liu, Xiaohui, Wiley, Joshua S., Vestal, Matthew L., Ramkissoon, Shakti H., Orringer, Daniel A., Gill, Kristen K., Dunn, Ian F., Dias-Santagata, Dora, Ligon, Keith L., Jolesz, Ferenc A., Golby, Alexandra J., Cooks, R. Graham, Agar, Nathalie Y. R.
Published in Proceedings of the National Academy of Sciences - PNAS (29.07.2014)
Published in Proceedings of the National Academy of Sciences - PNAS (29.07.2014)
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EGFR variant heterogeneity in glioblastoma resolved through single-nucleus sequencing
Francis, Joshua M, Zhang, Cheng-Zhong, Maire, Cecile L, Jung, Joonil, Manzo, Veronica E, Adalsteinsson, Viktor A, Homer, Heather, Haidar, Sam, Blumenstiel, Brendan, Pedamallu, Chandra Sekhar, Ligon, Azra H, Love, J Christopher, Meyerson, Matthew, Ligon, Keith L
Published in Cancer discovery (01.08.2014)
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Human Glioma Growth Is Controlled by MicroRNA-10b
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Published in Cancer research (Chicago, Ill.) (15.05.2011)
Published in Cancer research (Chicago, Ill.) (15.05.2011)
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The functional synergism of microRNA clustering provides therapeutically relevant epigenetic interference in glioblastoma
Bhaskaran, Vivek, Nowicki, Michal O, Idriss, Mahmoud, Jimenez, Miguel A, Lugli, Gianmarco, Hayes, Josie L, Mahmoud, Ahmad Bakur, Zane, Rachel E, Passaro, Carmela, Ligon, Keith L, Haas-Kogan, Daphne, Bronisz, Agnieszka, Godlewski, Jakub, Lawler, Sean E, Chiocca, E Antonio, Peruzzi, Pierpaolo
Published in Nature communications (25.01.2019)
Published in Nature communications (25.01.2019)
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Coactivation of Receptor Tyrosine Kinases Affects the Response of Tumor Cells to Targeted Therapies
Stommel, Jayne M, Kimmelman, Alec C, Ying, Haoqiang, Nabioullin, Roustem, Ponugoti, Aditya H, Wiedemeyer, Ruprecht, Stegh, Alexander H, Bradner, James E, Ligon, Keith L, Brennan, Cameron, Chin, Lynda, DePinho, Ronald A
Published in Science (American Association for the Advancement of Science) (12.10.2007)
Published in Science (American Association for the Advancement of Science) (12.10.2007)
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Glioblastoma Eradication Following Immune Checkpoint Blockade in an Orthotopic, Immunocompetent Model
Reardon, David A, Gokhale, Prafulla C, Klein, Sarah R, Ligon, Keith L, Rodig, Scott J, Ramkissoon, Shakti H, Jones, Kristen L, Conway, Amy Saur, Liao, Xiaoyun, Zhou, Jun, Wen, Patrick Y, Van Den Abbeele, Annick D, Hodi, F Stephen, Qin, Lei, Kohl, Nancy E, Sharpe, Arlene H, Dranoff, Glenn, Freeman, Gordon J
Published in Cancer immunology research (01.02.2016)
Published in Cancer immunology research (01.02.2016)
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