Next-Generation Hypoxic Cell Radiosensitizers: Nitroimidazole Alkylsulfonamides
Bonnet, Muriel, Hong, Cho Rong, Wong, Way Wua, Liew, Lydia P, Shome, Avik, Wang, Jingli, Gu, Yongchuan, Stevenson, Ralph J, Qi, Wen, Anderson, Robert F, Pruijn, Frederik B, Wilson, William R, Jamieson, Stephen M. F, Hicks, Kevin O, Hay, Michael P
Published in Journal of medicinal chemistry (08.02.2018)
Published in Journal of medicinal chemistry (08.02.2018)
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Journal Article
Design, Synthesis and Anticancer Evaluation of Nitroimidazole Radiosensitisers
Liew, Lydia P, Shome, Avik, Wong, Way W, Hong, Cho R, Hicks, Kevin O, Jamieson, Stephen M F, Hay, Michael P
Published in Molecules (Basel, Switzerland) (31.05.2023)
Published in Molecules (Basel, Switzerland) (31.05.2023)
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Journal Article
Hypoxia-selective radiosensitisation by SN38023, a bioreductive prodrug of DNA-dependent protein kinase inhibitor IC87361
Wong, Way Wua, Jackson, Rosanna K., Liew, Lydia P., Dickson, Benjamin D., Cheng, Gary J., Lipert, Barbara, Gu, Yongchuan, Hunter, Francis W., Wilson, William R., Hay, Michael P.
Published in Biochemical pharmacology (01.11.2019)
Published in Biochemical pharmacology (01.11.2019)
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Journal Article
Chemical Space Mimicry for Drug Discovery
Yuan, William, Jiang, Dadi, Nambiar, Dhanya K, Liew, Lydia P, Hay, Michael P, Bloomstein, Joshua, Lu, Peter, Turner, Brandon, Le, Quynh-Thu, Tibshirani, Robert, Khatri, Purvesh, Moloney, Mark G, Koong, Albert C
Published in Journal of chemical information and modeling (24.04.2017)
Published in Journal of chemical information and modeling (24.04.2017)
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Journal Article
Identification of 6‑Anilino Imidazo[4,5‑c]pyridin-2-ones as Selective DNA-Dependent Protein Kinase Inhibitors and Their Application as Radiosensitizers
Hong, Cho R., Liew, Lydia P., Wong, Way W., Dickson, Benjamin D., Cheng, Gary, Shome, Avik, Airey, Rebecca, Jaiswal, Jagdish, Lipert, Barbara, Jamieson, Stephen M. F., Wilson, William R., Hay, Michael P.
Published in Journal of medicinal chemistry (25.07.2024)
Published in Journal of medicinal chemistry (25.07.2024)
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Journal Article
Hypoxia‐Activated Prodrugs of PERK Inhibitors
Liew, Lydia P., Singleton, Dean C., Wong, Way W., Cheng, Gary J., Jamieson, Stephen M. F., Hay, Michael P.
Published in Chemistry, an Asian journal (15.04.2019)
Published in Chemistry, an Asian journal (15.04.2019)
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Journal Article
Synthesis and in vitro and in vivo evaluation of antimalarial polyamines
Liew, Lydia P.P., Pearce, A. Norrie, Kaiser, Marcel, Copp, Brent R.
Published in European journal of medicinal chemistry (01.11.2013)
Published in European journal of medicinal chemistry (01.11.2013)
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Journal Article
Synthesis of 1-indolyl substituted β-carboline natural products and discovery of antimalarial and cytotoxic activities
Liew, Lydia P.P., Fleming, Jessica M., Longeon, Arlette, Mouray, Elisabeth, Florent, Isabelle, Bourguet-Kondracki, Marie-Lise, Copp, Brent R.
Published in Tetrahedron (19.08.2014)
Published in Tetrahedron (19.08.2014)
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Identification of Small-Molecule Positive Modulators of Calcitonin-like Receptor-Based Receptors
Hendrikse, Erica R, Liew, Lydia P, Bower, Rebekah L, Bonnet, Muriel, Jamaluddin, Muhammad A, Prodan, Nicole, Richards, Keith D, Walker, Christopher S, Pairaudeau, Garry, Smith, David M, Rujan, Roxana-Maria, Sudra, Risha, Reynolds, Christopher A, Booe, Jason M, Pioszak, Augen A, Flanagan, Jack U, Hay, Michael P, Hay, Debbie L
Published in ACS pharmacology & translational science (10.04.2020)
Published in ACS pharmacology & translational science (10.04.2020)
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Journal Article
Identification of 6-Anilino Imidazo4,5-cpyridin-2-ones as Selective DNA-Dependent Protein Kinase Inhibitors and Their Application as Radiosensitizers
Hong, Cho R, Liew, Lydia P, Wong, Way W, Dickson, Benjamin D, Cheng, Gary, Shome, Avik, Airey, Rebecca, Jaiswal, Jagdish, Lipert, Barbara, Jamieson, Stephen M F, Wilson, William R, Hay, Michael P
Published in Journal of medicinal chemistry (25.07.2024)
Published in Journal of medicinal chemistry (25.07.2024)
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Journal Article
Abstract A004: Targeting tumor hypoxia with prodrugs of DNA-dependent protein kinase inhibitors
Liew, Lydia P., Hong, Cho R., Dickson, Benjamin D., Wong, Way W., Jamieson, Stephen M., Wilson, William R, Hay, Michael P.
Published in Cancer research (Chicago, Ill.) (09.01.2024)
Published in Cancer research (Chicago, Ill.) (09.01.2024)
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Abstract A001: Discovery of imidazo [4,5-c]pyridin-2-ones as selective inhibitors of DNA-dependent protein kinase and effective radiosensitizers
Hay, Michael P., Hong, Cho R., Liew, Lydia P., Dickson, Benjamin D., Wong, Way W., O'Brien-Gortner, Sophia F., Airey, Rebecca, Jaiswal, Jagdish, Wilson, William R., Jamieson, Stephen M.
Published in Cancer research (Chicago, Ill.) (09.01.2024)
Published in Cancer research (Chicago, Ill.) (09.01.2024)
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Journal Article
ChemInform Abstract: Synthesis of 1-Indolyl Substituted [beta]-Carboline Natural Products and Discovery of Antimalarial and Cytotoxic Activities
Liew, Lydia P P, Fleming, Jessica M, Longeon, Arlette, Mouray, Elisabeth, Florent, Isabelle, Bourguet-Kondracki, Marie-Lise, Copp, Brent R
Published in ChemInform (23.12.2014)
Published in ChemInform (23.12.2014)
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Journal Article
ChemInform Abstract: Synthesis of 1-Indolyl Substituted β-Carboline Natural Products and Discovery of Antimalarial and Cytotoxic Activities
Liew, Lydia P. P., Fleming, Jessica M., Longeon, Arlette, Mouray, Elisabeth, Florent, Isabelle, Bourguet-Kondracki, Marie-Lise, Copp, Brent R.
Published in ChemInform (23.12.2014)
Published in ChemInform (23.12.2014)
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