Mitochondria Are Required for Antigen-Specific T Cell Activation through Reactive Oxygen Species Signaling
Sena, Laura A., Li, Sha, Jairaman, Amit, Prakriya, Murali, Ezponda, Teresa, Hildeman, David A., Wang, Chyung-Ru, Schumacker, Paul T., Licht, Jonathan D., Perlman, Harris, Bryce, Paul J., Chandel, Navdeep S.
Published in Immunity (Cambridge, Mass.) (21.02.2013)
Published in Immunity (Cambridge, Mass.) (21.02.2013)
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The Proto-oncometabolite Fumarate Binds Glutathione to Amplify ROS-Dependent Signaling
Sullivan, Lucas B., Martinez-Garcia, Eva, Nguyen, Hien, Mullen, Andrew R., Dufour, Eric, Sudarshan, Sunil, Licht, Jonathan D., Deberardinis, Ralph J., Chandel, Navdeep S.
Published in Molecular cell (25.07.2013)
Published in Molecular cell (25.07.2013)
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Polycomb- and Methylation-Independent Roles of EZH2 as a Transcription Activator
Kim, Jung, Lee, Yongik, Lu, Xiaodong, Song, Bing, Fong, Ka-Wing, Cao, Qi, Licht, Jonathan D., Zhao, Jonathan C., Yu, Jindan
Published in Cell reports (Cambridge) (04.12.2018)
Published in Cell reports (Cambridge) (04.12.2018)
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FOXM1 regulates leukemia stem cell quiescence and survival in MLL-rearranged AML
Sheng, Yue, Yu, Chunjie, Liu, Yin, Hu, Chao, Ma, Rui, Lu, Xinyan, Ji, Peng, Chen, Jianjun, Mizukawa, Benjamin, Huang, Yong, Licht, Jonathan D, Qian, Zhijian
Published in Nature communications (17.02.2020)
Published in Nature communications (17.02.2020)
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Histone methyltransferase MMSET/NSD2 alters EZH2 binding and reprograms the myeloma epigenome through global and focal changes in H3K36 and H3K27 methylation
Popovic, Relja, Martinez-Garcia, Eva, Giannopoulou, Eugenia G, Zhang, Quanwei, Zhang, Qingyang, Ezponda, Teresa, Shah, Mrinal Y, Zheng, Yupeng, Will, Christine M, Small, Eliza C, Hua, Youjia, Bulic, Marinka, Jiang, Yanwen, Carrara, Matteo, Calogero, Raffaele A, Kath, William L, Kelleher, Neil L, Wang, Ji-Ping, Elemento, Olivier, Licht, Jonathan D
Published in PLoS genetics (01.09.2014)
Published in PLoS genetics (01.09.2014)
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EZH2 and BCL6 Cooperate to Assemble CBX8-BCOR Complex to Repress Bivalent Promoters, Mediate Germinal Center Formation and Lymphomagenesis
Béguelin, Wendy, Teater, Matt, Gearhart, Micah D., Calvo Fernández, María Teresa, Goldstein, Rebecca L., Cárdenas, Mariano G., Hatzi, Katerina, Rosen, Monica, Shen, Hao, Corcoran, Connie M., Hamline, Michelle Y., Gascoyne, Randy D., Levine, Ross L., Abdel-Wahab, Omar, Licht, Jonathan D., Shaknovich, Rita, Elemento, Olivier, Bardwell, Vivian J., Melnick, Ari M.
Published in Cancer cell (08.08.2016)
Published in Cancer cell (08.08.2016)
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EZH2 Is Required for Germinal Center Formation and Somatic EZH2 Mutations Promote Lymphoid Transformation
Béguelin, Wendy, Popovic, Relja, Teater, Matt, Jiang, Yanwen, Bunting, Karen L., Rosen, Monica, Shen, Hao, Yang, Shao Ning, Wang, Ling, Ezponda, Teresa, Martinez-Garcia, Eva, Zhang, Haikuo, Zheng, Yupeng, Verma, Sharad K., McCabe, Michael T., Ott, Heidi M., Van Aller, Glenn S., Kruger, Ryan G., Liu, Yan, McHugh, Charles F., Scott, David W., Chung, Young Rock, Kelleher, Neil, Shaknovich, Rita, Creasy, Caretha L., Gascoyne, Randy D., Wong, Kwok-Kin, Cerchietti, Leandro, Levine, Ross L., Abdel-Wahab, Omar, Licht, Jonathan D., Elemento, Olivier, Melnick, Ari M.
Published in Cancer cell (13.05.2013)
Published in Cancer cell (13.05.2013)
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DNA hydroxymethylation profiling reveals that WT1 mutations result in loss of TET2 function in acute myeloid leukemia
Rampal, Raajit, Alkalin, Altuna, Madzo, Jozef, Vasanthakumar, Aparna, Pronier, Elodie, Patel, Jay, Li, Yushan, Ahn, Jihae, Abdel-Wahab, Omar, Shih, Alan, Lu, Chao, Ward, Patrick S, Tsai, Jennifer J, Hricik, Todd, Tosello, Valeria, Tallman, Jacob E, Zhao, Xinyang, Daniels, Danette, Dai, Qing, Ciminio, Luisa, Aifantis, Iannis, He, Chuan, Fuks, Francois, Tallman, Martin S, Ferrando, Adolfo, Nimer, Stephen, Paietta, Elisabeth, Thompson, Craig B, Licht, Jonathan D, Mason, Christopher E, Godley, Lucy A, Melnick, Ari, Figueroa, Maria E, Levine, Ross L
Published in Cell reports (Cambridge) (11.12.2014)
Published in Cell reports (Cambridge) (11.12.2014)
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HIRA-mediated loading of histone variant H3.3 controls androgen-induced transcription by regulation of AR/BRD4 complex assembly at enhancers
Morozov, Viacheslav M, Riva, Alberto, Sarwar, Sadia, Kim, Wan-Ju, Li, Jianping, Zhou, Lei, Licht, Jonathan D, Daaka, Yehia, Ishov, Alexander M
Published in Nucleic acids research (27.10.2023)
Published in Nucleic acids research (27.10.2023)
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Leukemic IDH1 and IDH2 Mutations Result in a Hypermethylation Phenotype, Disrupt TET2 Function, and Impair Hematopoietic Differentiation
Figueroa, Maria E., Abdel-Wahab, Omar, Lu, Chao, Ward, Patrick S., Patel, Jay, Shih, Alan, Li, Yushan, Bhagwat, Neha, Vasanthakumar, Aparna, Fernandez, Hugo F., Tallman, Martin S., Sun, Zhuoxin, Wolniak, Kristy, Peeters, Justine K., Liu, Wei, Choe, Sung E., Fantin, Valeria R., Paietta, Elisabeth, Löwenberg, Bob, Licht, Jonathan D., Godley, Lucy A., Delwel, Ruud, Valk, Peter J.M., Thompson, Craig B., Levine, Ross L., Melnick, Ari
Published in Cancer cell (14.12.2010)
Published in Cancer cell (14.12.2010)
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HDAC8 Regulates a Stress Response Pathway in Melanoma to Mediate Escape from BRAF Inhibitor Therapy
Emmons, Michael F, Faião-Flores, Fernanda, Sharma, Ritin, Thapa, Ram, Messina, Jane L, Becker, Jurgen C, Schadendorf, Dirk, Seto, Edward, Sondak, Vernon K, Koomen, John M, Chen, Yian A, Lau, Eric K, Wan, Lixin, Licht, Jonathan D, Smalley, Keiran S M
Published in Cancer research (Chicago, Ill.) (01.06.2019)
Published in Cancer research (Chicago, Ill.) (01.06.2019)
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UTX/KDM6A Loss Enhances the Malignant Phenotype of Multiple Myeloma and Sensitizes Cells to EZH2 inhibition
Ezponda, Teresa, Dupéré-Richer, Daphné, Will, Christine M., Small, Eliza C., Varghese, Nobish, Patel, Tej, Nabet, Behnam, Popovic, Relja, Oyer, Jon, Bulic, Marinka, Zheng, Yupeng, Huang, Xiaoxiao, Shah, Mrinal Y., Maji, Sayantan, Riva, Alberto, Occhionorelli, Manuela, Tonon, Giovanni, Kelleher, Neil, Keats, Jonathan, Licht, Jonathan D.
Published in Cell reports (Cambridge) (17.10.2017)
Published in Cell reports (Cambridge) (17.10.2017)
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MDS and secondary AML display unique patterns and abundance of aberrant DNA methylation
Figueroa, Maria E., Skrabanek, Lucy, Li, Yushan, Jiemjit, Anchalee, Fandy, Tamer E., Paietta, Elisabeth, Fernandez, Hugo, Tallman, Martin S., Greally, John M., Carraway, Hetty, Licht, Jonathan D., Gore, Steven D., Melnick, Ari
Published in Blood (15.10.2009)
Published in Blood (15.10.2009)
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