Early-drug development in the era of immuno-oncology: are we ready to face the challenges?
Ochoa de Olza, M., Oliva, M., Hierro, C., Matos, I., Martin-Liberal, J., Garralda, E.
Published in Annals of oncology (01.08.2018)
Published in Annals of oncology (01.08.2018)
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Early-drug development in the era of immuno-oncology: are we ready to face the challenges?
Ochoa de Olza, M.O., Oliva, M., Hierro, C., Matos, I., Martin-Liberal, J., Garralda, E.
Published in Annals of oncology (01.10.2019)
Published in Annals of oncology (01.10.2019)
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Phase I trial of sorafenib in combination with ifosfamide in patients with advanced sarcoma: a Spanish group for research on sarcomas (GEIS) study
Martín-Liberal, J., López-Pousa, A., Broto, J. Martín, Cubedo, R., Gallego, O., Brendel, E., Tirado, O. M., del Muro, X. García
Published in Investigational new drugs (01.04.2014)
Published in Investigational new drugs (01.04.2014)
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Refining criteria of hyperprogression (HPD) with immune checkpoint inhibitors (ICIs) to improve clinical applicability
Matos Garcia, I., García Ruiz, A., Martin-Liberal, J., Hierro, C., Ochoa De Olza Amat, M., Viaplana, C., Mur, G., Vieito Villar, M., Brana, I., Azaro, A., Perez, C., Rodriguez Freixinos, V., Argiles, G., Oliveira, M., Felip Font, E., Muñoz-Couselo, E., Tabernero, J., Dienstmann, R., Garralda, E.
Published in Annals of oncology (01.10.2018)
Published in Annals of oncology (01.10.2018)
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Immune prognostic index (IPI) and hyper-progressive disease (HPD) in patients (pts) exposed to targeted agents (TAs) in phase I trials (Ph1T): Can lessons from immune checkpoint inhibitors (ICIs) be translated to other scenarios?
Matos Garcia, I., Azaro, A., Viaplana, C., Hierro, C., Martin-Liberal, J., Brana, I., Gardeazabal, I., Gomila, P., Vieito Villar, M., Ochoa De Olza Amat, M., Elez Fernandez, E., Oliveira, M., Oaknin, A., Verdaguer, H., Navarro Mendivil, A., Alsina, M., Tabernero, J., Macarulla Mercade, T., Dienstmann, R., Garralda, E.
Published in Annals of oncology (01.10.2018)
Published in Annals of oncology (01.10.2018)
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Tumor infiltrating lymphocytes (TILs) and PDL1 expression as prescreening enrichment biomarkers of clinical benefit to immune checkpoint inhibitors (CI) in early clinical trials (ECT)
Martin-Liberal, J., Pagliuca, F., Hierro, C., Viaplana, C., Muñoz Couselo, E., Capdevila, J., Matos, I., Fariñas Madrid, L., Zamora, E., Braña Garcia, I., Elez Fernandez, E., Ochoa De Olza Amat, M., Azaro, A., Alsina, M., Vieito Villar, M., Fasani, R., Tabernero, J., Garralda, E., Dienstmann, R., Nuciforo, P.G.
Published in Annals of oncology (01.10.2018)
Published in Annals of oncology (01.10.2018)
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Clinical activity, safety, and PK/PD from a phase I study of RO6874281, a fibroblast activation protein (FAP) targeted interleukin-2 variant (IL-2v)
Melero, I, Castanon Alvarez, E, Mau-Sorensen, M, Lassen, U N, Lolkema, M P, Robbrecht, D G, Gomez-Roca, C A, Martin-Liberal, J, Tabernero, J, Ros, W, Ahmed, S, Isambert, N, Piper Lepoutre, H, Boetsch, C, Charo, J, Evers, S, Teichgräber, V, Schellens, J H M
Published in Annals of oncology (01.10.2018)
Published in Annals of oncology (01.10.2018)
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AZD8186, a potent and selective inhibitor of PI3Kβ/δ, as monotherapy and in combination with abiraterone acetate plus prednisone (AAP), in patients (pts) with metastatic castrate-resistant prostate cancer (mCRPC)
de Bono, J.S., Hansen, A., Choudhury, A.D., Cook, N., Heath, E.I., Higano, C., Linch, M., Martin-Liberal, J., Rathkopf, D.E., Wisinski, K.B., Barry, S., de Bruin, E., Brugger, W., Colebrook, S., Klinowska, T., Moschetta, M., Mortimer, P.G.S., Siu, L.L., Shapiro, G.
Published in Annals of oncology (01.10.2018)
Published in Annals of oncology (01.10.2018)
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First in human study with GSK3359609 [GSK609], inducible T cell co-stimulator (ICOS) receptor agonist in patients [Pts] with advanced, solid tumors: Preliminary results from INDUCE-1
Hansen, A., Bauer, T.M., Moreno, V., Maio, M., Groenland, S., Martin-Liberal, J., Gan, H., Rischin, D., Millward, M., Olszanski, A.J., Cho, D.C., Paul, E., Ballas, M., Ellis, C., Zhou, H., Yadavilli, S., Sadik Shaik, J., Schmidt, E.V., Hoos, A., Angevin, E.
Published in Annals of oncology (01.10.2018)
Published in Annals of oncology (01.10.2018)
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Vall d’Hebron Institute of Oncology (VHIO) immuno-oncology prognostic index (VIO): A new tool for improved patient (pt) selection in phase I (Ph1) trials with immune checkpoint inhibitors (ICI)
Hierro, C., Matos, I., Martin-Liberal, J., Ochoa De Olza Amat, M., Felip, E., Costa Rivas, M., Vieito Villar, M., Brana, I., Azaro, A., Perez-Gago, M.C., Gros, A., Carles, J., Oaknin, A., Macarulla, T., Saura, C., pardo, N., Muñoz-Couselo, E., Tabernero, J., Dienstmann, R., Garralda, E.
Published in Annals of oncology (01.10.2018)
Published in Annals of oncology (01.10.2018)
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Phase I study and preclinical efficacy evaluation of the mTOR inhibitor sirolimus plus gemcitabine in patients with advanced solid tumours
MARTIN-LIBERAL, J, GIL-MARTIN, M, SAINZ-JASPEADO, M, GONZALO, N, RIGO, R, COLOM, H, MUNOZ, C, TIRADO, O. M, DEL MURO, X. Garcia
Published in British journal of cancer (26.08.2014)
Published in British journal of cancer (26.08.2014)
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Targeting protein kinase C in sarcoma
Martin-Liberal, J., Cameron, A.J., Claus, J., Judson, I.R., Parker, P.J., Linch, M.
Published in Biochimica et biophysica acta (01.12.2014)
Published in Biochimica et biophysica acta (01.12.2014)
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Early interventions to detect potential drug–drug interactions on patient eligibility for phase 1 clinical trials
Azaro, A, Ghiglione, L, Valdivia, C, Munné, M, Renedo, B, Sabaté, N, Alcalde, M, Braña, I, Hierro, C, Martin-Liberal, J, Ochoa de Olza, M, Argiles Martínez, G, Vilaró, M, Tabernero, J, Rodon, J
Published in European journal of cancer (1990) (01.12.2016)
Published in European journal of cancer (1990) (01.12.2016)
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Margotia gummifera essential oil as a source of anti-inflammatory drugs
Valente, J., Zuzarte, M., Liberal, J., Gonçalves, M.J., Lopes, M.C., Cavaleiro, C., Cruz, M.T., Salgueiro, L.
Published in Industrial crops and products (01.05.2013)
Published in Industrial crops and products (01.05.2013)
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