Insulator dysfunction and oncogene activation in IDH mutant gliomas
Flavahan, William A., Drier, Yotam, Liau, Brian B., Gillespie, Shawn M., Venteicher, Andrew S., Stemmer-Rachamimov, Anat O., Suvà, Mario L., Bernstein, Bradley E.
Published in Nature (London) (07.01.2016)
Published in Nature (London) (07.01.2016)
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Adaptive Chromatin Remodeling Drives Glioblastoma Stem Cell Plasticity and Drug Tolerance
Liau, Brian B., Sievers, Cem, Donohue, Laura K., Gillespie, Shawn M., Flavahan, William A., Miller, Tyler E., Venteicher, Andrew S., Hebert, Christine H., Carey, Christopher D., Rodig, Scott J., Shareef, Sarah J., Najm, Fadi J., van Galen, Peter, Wakimoto, Hiroaki, Cahill, Daniel P., Rich, Jeremy N., Aster, Jon C., Suvà, Mario L., Patel, Anoop P., Bernstein, Bradley E.
Published in Cell stem cell (02.02.2017)
Published in Cell stem cell (02.02.2017)
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Journal Article
Mediator kinase inhibition further activates super-enhancer-associated genes in AML
Pelish, Henry E., Liau, Brian B., Nitulescu, Ioana I., Tangpeerachaikul, Anupong, Poss, Zachary C., Da Silva, Diogo H., Caruso, Brittany T., Arefolov, Alexander, Fadeyi, Olugbeminiyi, Christie, Amanda L., Du, Karrie, Banka, Deepti, Schneider, Elisabeth V., Jestel, Anja, Zou, Ge, Si, Chong, Ebmeier, Christopher C., Bronson, Roderick T., Krivtsov, Andrei V., Myers, Andrew G., Kohl, Nancy E., Kung, Andrew L., Armstrong, Scott A., Lemieux, Madeleine E., Taatjes, Dylan J., Shair, Matthew D.
Published in Nature (London) (08.10.2015)
Published in Nature (London) (08.10.2015)
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Journal Article
Transcription elongation factors represent in vivo cancer dependencies in glioblastoma
Miller, Tyler E., Liau, Brian B., Wallace, Lisa C., Morton, Andrew R., Xie, Qi, Dixit, Deobrat, Factor, Daniel C., Kim, Leo J. Y., Morrow, James J., Wu, Qiulian, Mack, Stephen C., Hubert, Christopher G., Gillespie, Shawn M., Flavahan, William A., Hoffmann, Thomas, Thummalapalli, Rohit, Hemann, Michael T., Paddison, Patrick J., Horbinski, Craig M., Zuber, Johannes, Scacheri, Peter C., Bernstein, Bradley E., Tesar, Paul J., Rich, Jeremy N.
Published in Nature (London) (20.07.2017)
Published in Nature (London) (20.07.2017)
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Journal Article
A Unified Strategy for the Synthesis of 7‑Membered-Ring-Containing Lycopodium Alkaloids
Lee, Amy S, Liau, Brian B, Shair, Matthew D
Published in Journal of the American Chemical Society (24.09.2014)
Published in Journal of the American Chemical Society (24.09.2014)
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Journal Article
Base editor scanning charts the DNMT3A activity landscape
Lue, Nicholas Z., Garcia, Emma M., Ngan, Kevin C., Lee, Ceejay, Doench, John G., Liau, Brian B.
Published in Nature chemical biology (01.02.2023)
Published in Nature chemical biology (01.02.2023)
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Journal Article
Challenges of glycosylation analysis and control: an integrated approach to producing optimal and consistent therapeutic drugs
Zhang, Peiqing, Woen, Susanto, Wang, Tianhua, Liau, Brian, Zhao, Sophie, Chen, Chen, Yang, Yuansheng, Song, Zhiwei, Wormald, Mark R., Yu, Chuanfei, Rudd, Pauline M.
Published in Drug discovery today (01.05.2016)
Published in Drug discovery today (01.05.2016)
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Systematic identification of anticancer drug targets reveals a nucleus-to-mitochondria ROS-sensing pathway
Zhang, Junbing, Simpson, Claire M., Berner, Jacqueline, Chong, Harrison B., Fang, Jiafeng, Ordulu, Zehra, Weiss-Sadan, Tommy, Possemato, Anthony P., Harry, Stefan, Takahashi, Mariko, Yang, Tzu-yi, Richter, Marianne, Patel, Himani, Smith, Abby E., Carlin, Alexander D., Hubertus de Groot, Adriaan F., Wolf, Konstantin, Shi, Lei, Wei, Ting-Yu, Dürr, Benedikt R., Chen, Nicholas J., Vornbäumen, Tristan, Wichmann, Nina O., Mahamdeh, Mohammed S., Pooladanda, Venkatesh, Matoba, Yusuke, Kumar, Shaan, Kim, Eugene, Bouberhan, Sara, Oliva, Esther, Rueda, Bo R., Soberman, Roy J., Bardeesy, Nabeel, Liau, Brian B., Lawrence, Michael, Stokes, Matt P., Beausoleil, Sean A., Bar-Peled, Liron
Published in Cell (25.05.2023)
Published in Cell (25.05.2023)
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CRISPR-suppressor scanning reveals a nonenzymatic role of LSD1 in AML
Vinyard, Michael E., Su, Cindy, Siegenfeld, Allison P., Waterbury, Amanda L., Freedy, Allyson M., Gosavi, Pallavi M., Park, Yongho, Kwan, Eugene E., Senzer, Benjamin D., Doench, John G., Bauer, Daniel E., Pinello, Luca, Liau, Brian B.
Published in Nature chemical biology (01.05.2019)
Published in Nature chemical biology (01.05.2019)
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Journal Article
Polycomb-lamina antagonism partitions heterochromatin at the nuclear periphery
Siegenfeld, Allison P., Roseman, Shelby A., Roh, Heejin, Lue, Nicholas Z., Wagen, Corin C., Zhou, Eric, Johnstone, Sarah E., Aryee, Martin J., Liau, Brian B.
Published in Nature communications (20.07.2022)
Published in Nature communications (20.07.2022)
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Journal Article
Gain-of-Function Genetic Alterations of G9a Drive Oncogenesis
Kato, Shinichiro, Weng, Qing Yu, Insco, Megan L, Chen, Kevin Y, Muralidhar, Sathya, Pozniak, Joanna, Diaz, Joey Mark S, Drier, Yotam, Nguyen, Nhu, Lo, Jennifer A, van Rooijen, Ellen, Kemeny, Lajos V, Zhan, Yao, Feng, Yang, Silkworth, Whitney, Powell, C Thomas, Liau, Brian B, Xiong, Yan, Jin, Jian, Newton-Bishop, Julia, Zon, Leonard I, Bernstein, Bradley E, Fisher, David E
Published in Cancer discovery (01.07.2020)
Published in Cancer discovery (01.07.2020)
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Journal Article
A Multiplexed System for Quantitative Comparisons of Chromatin Landscapes
van Galen, Peter, Viny, Aaron D., Ram, Oren, Ryan, Russell J.H., Cotton, Matthew J., Donohue, Laura, Sievers, Cem, Drier, Yotam, Liau, Brian B., Gillespie, Shawn M., Carroll, Kaitlin M., Cross, Michael B., Levine, Ross L., Bernstein, Bradley E.
Published in Molecular cell (07.01.2016)
Published in Molecular cell (07.01.2016)
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