Discovery of Ledipasvir (GS-5885): A Potent, Once-Daily Oral NS5A Inhibitor for the Treatment of Hepatitis C Virus Infection
Link, John O., Taylor, James G., Xu, Lianhong, Mitchell, Michael, Guo, Hongyan, Liu, Hongtao, Kato, Darryl, Kirschberg, Thorsten, Sun, Jianyu, Squires, Neil, Parrish, Jay, Keller, Terry, Yang, Zheng-Yu, Yang, Chris, Matles, Mike, Wang, Yujin, Wang, Kelly, Cheng, Guofeng, Tian, Yang, Mogalian, Erik, Mondou, Elsa, Cornpropst, Melanie, Perry, Jason, Desai, Manoj C.
Published in Journal of medicinal chemistry (13.03.2014)
Published in Journal of medicinal chemistry (13.03.2014)
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Wogonin inhibits in vitro herpes simplex virus type 1 and 2 infection by modulating cellular NF-κB and MAPK pathways
Chu, Ying, Lv, Xiaowen, Zhang, Longfeng, Fu, Xingli, Song, Siwei, Su, Airong, Chen, Deyan, Xu, Lianhong, Wang, Yongfang, Wu, Zhiwei, Yun, Zhihua
Published in BMC microbiology (28.07.2020)
Published in BMC microbiology (28.07.2020)
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Cobicistat (GS-9350): A Potent and Selective Inhibitor of Human CYP3A as a Novel Pharmacoenhancer
Xu, Lianhong, Liu, Hongtao, Murray, Bernard P, Callebaut, Christian, Lee, Melody S, Hong, Allen, Strickley, Robert G, Tsai, Luong K, Stray, Kirsten M, Wang, Yujin, Rhodes, Gerry R, Desai, Manoj C
Published in ACS medicinal chemistry letters (12.08.2010)
Published in ACS medicinal chemistry letters (12.08.2010)
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Relationship between warfarin dosage and international normalized ratio: a dose–response analysis and evaluation based on multicenter data
Xue, Ling, Zhang, Yuzhen, Xie, Cheng, Zhou, Ling, Liu, Linsheng, Zhang, Haiyan, Xu, Lianhong, Song, Hongtao, Lin, Meiqin, Qiu, Hanfan, Zhu, Junrong, Zhu, Yubing, Zou, Jianjun, Zhuang, Wenfang, Xuan, Binbin, Chen, Yanhong, Fan, Yingchao, Wu, Di, Shen, Zhenya, Miao, Liyan
Published in European journal of clinical pharmacology (01.06.2019)
Published in European journal of clinical pharmacology (01.06.2019)
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Interrelationships between ALOX5AP polymorphisms, serum leukotriene B4 level and risk of acute coronary syndrome
He, Guoping, Ye, Shan, Hui, Jingjiao, Shen, Dandan, Qi, Chuanping, Xu, Lianhong, Qian, Yichao
Published in PloS one (11.09.2014)
Published in PloS one (11.09.2014)
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Preclinical Characterization of GS-9669, a Thumb Site II Inhibitor of the Hepatitis C Virus NS5B Polymerase
FENAUX, Martijn, ENG, Stacey, LAZERWITH, Scott E, LEW, Willard, QI LIU, MERTZMAN, Michael, MORGANELLI, Philip, LIANHONG XU, HONG YE, JENNIFER ZHANG, MATLES, Mike, MURRAY, Bernard P, LEAVITT, Stephanie A, MWANGI, Judy, JINGYU ZHANG, HASHASH, Ahmad, KRAWCZYK, Steve H, BIDGOOD, Alison M, APPLEBY, Todd C, WATKINS, William J, LEE, Yu-Jen, MABERY, Eric M, YANG TIAN, BYUN, Daniel, CANALES, Eda, CLARKE, Michael O, DOERFFLER, Edward
Published in Antimicrobial Agents and Chemotherapy (01.02.2013)
Published in Antimicrobial Agents and Chemotherapy (01.02.2013)
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Journal Article
Correction to Discovery of Ledipasvir (GS-5885): A Potent, Once-Daily Oral NS5A Inhibitor for the Treatment of Hepatitis C Virus Infection
Link, John O, Taylor, James G, Xu, Lianhong, Mitchell, Michael, Guo, Hongyan, Liu, Hongtao, Kato, Darryl, Kirschberg, Thorsten, Sun, Jianyu, Squires, Neil, Parrish, Jay, Kellar, Terry, Yang, Zheng-Yu, Yang, Chris, Matles, Mike, Wang, Yujin, Wang, Kelly, Cheng, Guofeng, Tian, Yang, Mogalian, Erik, Mondou, Elsa, Cornpropst, Melanie, Perry, Jason, Desai, Manoj C
Published in Journal of medicinal chemistry (25.08.2016)
Published in Journal of medicinal chemistry (25.08.2016)
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Journal Article
In Vitro Characterization of GS-8374, a Novel Phosphonate-Containing Inhibitor of HIV-1 Protease with a Favorable Resistance Profile
CALLEBAUT, Christian, STRAY, Kirsten, MULATO, Andrew, HATADA, Marcos, PRISKICH, Tina, PARKIN, Neil, SWAMINATHAN, Swami, LEE, William, HE, Gong-Xin, LIANHONG XU, CIHLAR, Tomas, TSAI, Luong, WILLIAMS, Matt, YANG, Zheng-Yu, CANNIZZARO, Carina, LEAVITT, Stephanie A, XIAOHONG LIU, KELLY WANG, MURRAY, Bernard P
Published in Antimicrobial Agents and Chemotherapy (01.04.2011)
Published in Antimicrobial Agents and Chemotherapy (01.04.2011)
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Structure–activity relationships of diamine inhibitors of cytochrome P450 (CYP) 3A as novel pharmacoenhancers, part I: Core region
Liu, Hongtao, Xu, Lianhong, Hui, Hon, Vivian, Randy, Callebaut, Christian, Murray, Bernard P., Hong, Allen, Lee, Melody S., Tsai, Luong K., Chau, Jennifer K., Stray, Kirsten M., Cannizzaro, Carina, Choi, You-Chul, Rhodes, Gerry R., Desai, Manoj C.
Published in Bioorganic & medicinal chemistry letters (01.02.2014)
Published in Bioorganic & medicinal chemistry letters (01.02.2014)
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Journal Article
GS-8374, a Novel HIV Protease Inhibitor, Does Not Alter Glucose Homeostasis in Cultured Adipocytes or in a Healthy-Rodent Model System
HRUZ, Paul W, QINGYUN YAN, TSAI, Luong, KOSTER, Joseph, LIANHONG XU, CIHLAR, Tomas, CALLEBAUT, Christian
Published in Antimicrobial Agents and Chemotherapy (01.04.2011)
Published in Antimicrobial Agents and Chemotherapy (01.04.2011)
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N1-Heterocyclic pyrimidinediones as non-nucleoside inhibitors of HIV-1 reverse transcriptase
Mitchell, Michael L., Son, Jong Chan, Lee, Ill Young, Lee, Chong-Kyo, Kim, Hae Soo, Guo, Hongyan, Wang, Jianhong, Hayes, Jaclyn, Wang, Michael, Paul, Amber, Lansdon, Eric B., Chen, James M., Eisenberg, Gene, Geleziunas, Romas, Xu, Lianhong, Kim, Choung U.
Published in Bioorganic & medicinal chemistry letters (01.03.2010)
Published in Bioorganic & medicinal chemistry letters (01.03.2010)
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SAR studies on dihydropyrimidinone antibiotics
Xu, Lianhong, Zhang, Lijun, Jones, Robert, Bryant, Clifford, Boddeker, Nina, Mabery, Eric, Bahador, Gina, Watson, Julia, Clough, Jeffery, Arimilli, Murty, Gillette, Wendy, Colagiovanni, Dorothy, Wang, Keyu, Gibbs, Craig, Kim, Choung U.
Published in Bioorganic & medicinal chemistry letters (15.03.2011)
Published in Bioorganic & medicinal chemistry letters (15.03.2011)
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Journal Article
N1-Alkyl pyrimidinediones as non-nucleoside inhibitors of HIV-1 reverse transcriptase
Mitchell, Michael L., Son, Jong Chan, Guo, Hongyan, Im, Yun-A, Cho, Eun Jung, Wang, Jianhong, Hayes, Jaclyn, Wang, Michael, Paul, Amber, Lansdon, Eric B., Chen, James M., Graupe, Doris, Rhodes, Gerry, He, Gong-Xin, Geleziunas, Romas, Xu, Lianhong, Kim, Choung U.
Published in Bioorganic & medicinal chemistry letters (01.03.2010)
Published in Bioorganic & medicinal chemistry letters (01.03.2010)
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Design, synthesis and characterizations of prodrugs of brexanolone
Xu, Lianhong, Ma, Ji, Shi, Leifeng, Li, Fuying
Published in Bioorganic & medicinal chemistry letters (15.06.2023)
Published in Bioorganic & medicinal chemistry letters (15.06.2023)
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Retraction notice to “miR-1271 promotes non-small-cell lung cancer cell proliferation and invasion via targeting HOXA5” [Biochem. Biophys. Res. Commun. 458/3 (2015) 714–719]
Wang, Yongfang, Xu, Lianhong, Jiang, Lixin
Published in Biochemical and biophysical research communications (06.08.2019)
Published in Biochemical and biophysical research communications (06.08.2019)
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Total synthesis of (.+-.)-FR-900482
Fukuyama, Tohru, Xu, Lianhong, Goto, Shunsuke
Published in Journal of the American Chemical Society (01.01.1992)
Published in Journal of the American Chemical Society (01.01.1992)
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Preclinical characterization of a non-peptidomimetic HIV protease inhibitor with improved metabolic stability
Mulato, Andrew, Lansdon, Eric, Aoyama, Ron, Voigt, Johannes, Lee, Michael, Liclican, Albert, Lee, Gary, Singer, Eric, Stafford, Brian, Gong, Ruoyu, Murray, Bernard, Chan, Julie, Lee, Johnny, Xu, Yili, Ahmadyar, Shekeba, Gonzalez, Ana, Cho, Aesop, Stepan, George J, Schmitz, Uli, Schultz, Brian, Marchand, Bruno, Brumshtein, Boris, Wang, Ruth, Yu, Helen, Cihlar, Tomas, Xu, Lianhong, Yant, Stephen R
Published in Antimicrobial agents and chemotherapy (03.04.2024)
Published in Antimicrobial agents and chemotherapy (03.04.2024)
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