The emerging roles of artificial intelligence in cancer drug development and precision therapy
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Published in Biomedicine & pharmacotherapy (01.08.2020)
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Linden, Albert G., Li, Shili, Choi, Hwa Y., Fang, Fei, Fukasawa, Masashi, Uyeda, Kosaku, Hammer, Robert E., Horton, Jay D., Engelking, Luke J., Liang, Guosheng
Published in Journal of lipid research (01.03.2018)
Published in Journal of lipid research (01.03.2018)
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25-Hydroxycholesterol suppresses interleukin-1-driven inflammation downstream of type I interferon
Reboldi, Andrea, Dang, Eric V., McDonald, Jeffrey G., Liang, Guosheng, Russell, David W., Cyster, Jason G.
Published in Science (American Association for the Advancement of Science) (08.08.2014)
Published in Science (American Association for the Advancement of Science) (08.08.2014)
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Expression of SREBP-1c Requires SREBP-2-mediated Generation of a Sterol Ligand for LXR in Livers of Mice
Rong, Shunxing, Cortés, Víctor A, Rashid, Shirya, Anderson, Norma N, McDonald, Jeffrey G, Liang, Guosheng, Moon, Young-Ah, Hammer, Robert E, Horton, Jay D
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Published in eLife (28.02.2017)
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Unexpected role for IGF-1 in starvation: Maintenance of blood glucose
Fang, Fei, Goldstein, Joseph L, Shi, Xuanming, Liang, Guosheng, Brown, Michael S
Published in Proceedings of the National Academy of Sciences - PNAS (09.08.2022)
Published in Proceedings of the National Academy of Sciences - PNAS (09.08.2022)
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Insulin stimulation of SREBP-1c processing in transgenic rat hepatocytes requires p70 S6-kinase
Owen, Joshua L, Zhang, Yuanyuan, Bae, Soo-Han, Farooqi, Midhat S, Liang, Guosheng, Hammer, Robert E, Goldstein, Joseph L, Brown, Michael S
Published in Proceedings of the National Academy of Sciences - PNAS (02.10.2012)
Published in Proceedings of the National Academy of Sciences - PNAS (02.10.2012)
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The Scap/SREBP Pathway Is Essential for Developing Diabetic Fatty Liver and Carbohydrate-Induced Hypertriglyceridemia in Animals
Moon, Young-Ah, Liang, Guosheng, Xie, Xuefen, Frank-Kamenetsky, Maria, Fitzgerald, Kevin, Koteliansky, Victor, Brown, Michael S., Goldstein, Joseph L., Horton, Jay D.
Published in Cell metabolism (08.02.2012)
Published in Cell metabolism (08.02.2012)
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Growth hormone acts on liver to stimulate autophagy, support glucose production, and preserve blood glucose in chronically starved mice
Fang, Fei, Shi, Xuanming, Brown, Michael S., Goldstein, Joseph L., Liang, Guosheng
Published in Proceedings of the National Academy of Sciences - PNAS (09.04.2019)
Published in Proceedings of the National Academy of Sciences - PNAS (09.04.2019)
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Ghrelin O-acyltransferase (GOAT) is essential for growth hormone-mediated survival of calorie-restricted mice
Zhao, Tong-Jin, Liang, Guosheng, Li, Robert Lin, Xie, Xuefen, Sleeman, Mark W, Murphy, Andrew J, Valenzuela, David M, Yancopoulos, George D, Goldstein, Joseph L, Brown, Michael S
Published in Proceedings of the National Academy of Sciences - PNAS (20.04.2010)
Published in Proceedings of the National Academy of Sciences - PNAS (20.04.2010)
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DHHC4 and DHHC5 Facilitate Fatty Acid Uptake by Palmitoylating and Targeting CD36 to the Plasma Membrane
Wang, Juan, Hao, Jian-Wei, Wang, Xu, Guo, Huiling, Sun, Hui-Hui, Lai, Xiao-Ying, Liu, Li-Ying, Zhu, Mingxia, Wang, Hao-Yan, Li, Yi-Fan, Yu, Li-Yang, Xie, Changchuan, Wang, Hong-Rui, Mo, Wei, Zhou, Hai-Meng, Chen, Shuai, Liang, Guosheng, Zhao, Tong-Jin
Published in Cell reports (Cambridge) (02.01.2019)
Published in Cell reports (Cambridge) (02.01.2019)
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25-Hydroxycholesterol secreted by macrophages in response to Toll-like receptor activation suppresses immunoglobulin A production
Bauman, David R, Bitmansour, Andrew D, McDonald, Jeffrey G, Thompson, Bonne M, Liang, Guosheng, Russell, David W
Published in Proceedings of the National Academy of Sciences - PNAS (29.09.2009)
Published in Proceedings of the National Academy of Sciences - PNAS (29.09.2009)
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Clinical and Prognostic Pan-Cancer Analysis of N6-Methyladenosine Regulators in Two Types of Hematological Malignancies: A Retrospective Study Based on TCGA and GTEx Databases
Zhang, Xiangsheng, Zhong, Liye, Zou, Zhilin, Liang, Guosheng, Tang, Zhenye, Li, Kai, Tan, Shuzhen, Huang, Yongmei, Zhu, Xiao
Published in Frontiers in oncology (18.03.2021)
Published in Frontiers in oncology (18.03.2021)
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Ghrelin secretion stimulated by β₁-adrenergic receptors in cultured ghrelinoma cells and in fasted mice
Zhao, Tong-Jin, Sakata, Ichiro, Li, Robert Lin, Liang, Guosheng, Richardson, James A, Brown, Michael S, Goldstein, Joseph L, Zigman, Jeffrey M
Published in Proceedings of the National Academy of Sciences - PNAS (07.09.2010)
Published in Proceedings of the National Academy of Sciences - PNAS (07.09.2010)
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The Xbp1s/GalE axis links ER stress to postprandial hepatic metabolism
Deng, Yingfeng, Wang, Zhao V, Tao, Caroline, Gao, Ningguo, Holland, William L, Ferdous, Anwarul, Repa, Joyce J, Liang, Guosheng, Ye, Jin, Lehrman, Mark A, Hill, Joseph A, Horton, Jay D, Scherer, Philipp E
Published in The Journal of clinical investigation (01.01.2013)
Published in The Journal of clinical investigation (01.01.2013)
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Deficiency of Carbohydrate Response Element-Binding Protein (ChREBP) Reduces Lipogenesis as Well as Glycolysis
Iizuka, Katsumi, Bruick, Richard K., Liang, Guosheng, Horton, Jay D., Uyeda, Kosaku, McKnight, Steven L.
Published in Proceedings of the National Academy of Sciences - PNAS (11.05.2004)
Published in Proceedings of the National Academy of Sciences - PNAS (11.05.2004)
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Response to Kunos et al. and Lotersztajn and Mallat
Wang, Simeng, Zhu, Qingzhang, Liang, Guosheng, Franks, Tania, Boucher, Magalie, Bence, Kendra K, Lu, Mingjian, Castorena, Carlos M, Zhao, Shangang, Elmquist, Joel K, Scherer, Philipp E, Horton, Jay D
Published in The Journal of clinical investigation (04.01.2022)
Published in The Journal of clinical investigation (04.01.2022)
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Central Role for Liver X Receptor in Insulin-Mediated Activation of Srebp-1c Transcription and Stimulation of Fatty Acid Synthesis in Liver
Chen, Guoxun, Liang, Guosheng, Ou, Jiafu, Goldstein, Joseph L., Brown, Michael S.
Published in Proceedings of the National Academy of Sciences - PNAS (03.08.2004)
Published in Proceedings of the National Academy of Sciences - PNAS (03.08.2004)
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Critical Role of SREBP-1c Large-VLDL Pathway in Environment-Induced Hypertriglyceridemia of Apo AV Deficiency
Takanashi, Mikio, Kimura, Takeshi, Li, Chengcheng, Tanaka, Masaki, Matsuhashi, Ako, Yoshida, Hiroki, Noda, Akari, Xu, Pengfei, Takase, Satoru, Okazaki, Sachiko, Iizuka, Yoko, Kumagai, Hidetoshi, Ikeda, Yuichi, Gotoda, Takanari, Takahashi, Manabu, Yagyu, Hiroaki, Ishibashi, Shun, Yamauchi, Toshimasa, Kadowaki, Takashi, Liang, Guosheng, Okazaki, Hiroaki
Published in Arteriosclerosis, thrombosis, and vascular biology (01.03.2019)
Published in Arteriosclerosis, thrombosis, and vascular biology (01.03.2019)
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