Inhibition of Hsp110-STAT3 interaction in endothelial cells alleviates vascular remodeling in hypoxic pulmonary arterial Hypertension model
Zhao, Congke, Le, Xiangyang, Li, Mengqi, Hu, Yuanbo, Li, Xiaohui, Chen, Zhuo, Hu, Gaoyun, Hu, Liqing, Li, Qianbin
Published in Respiratory research (17.11.2023)
Published in Respiratory research (17.11.2023)
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A first-in-class inhibitor of Hsp110 molecular chaperones of pathogenic fungi
Hu, Liqing, Sun, Cancan, Kidd, Justin M, Han, Jizhong, Fang, Xianjun, Li, Hongtao, Liu, Qingdai, May, Aaron E, Li, Qianbin, Zhou, Lei, Liu, Qinglian
Published in Nature communications (12.05.2023)
Published in Nature communications (12.05.2023)
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Discovery of Ureido-Based Apcin Analogues as Cdc20-specific Inhibitors against Cancer
He, Yiqin, Le, Xiangyang, Hu, Gaoyun, Li, Qianbin, Chen, Zhuo
Published in Pharmaceuticals (Basel, Switzerland) (01.02.2023)
Published in Pharmaceuticals (Basel, Switzerland) (01.02.2023)
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Fluorofenidone protects against acute kidney injury
Jiang, YuPeng, Quan, Jiao, Chen, Yang, Liao, Xiaohua, Dai, Qin, Lu, Rong, Yu, Yue, Hu, Gaoyun, Li, Qianbin, Meng, Jie, Xie, Yanyun, Peng, Zhangzhe, Tao, Lijian
Published in The FASEB journal (01.12.2019)
Published in The FASEB journal (01.12.2019)
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Soluble Guanylate Cyclase Stimulators and Activators: Where are We and Where to Go?
Xiao, Sijia, Li, Qianbin, Hu, Liqing, Yu, Zutao, Yang, Jie, Chang, Qi, Chen, Zhuo, Hu, Gaoyun
Published in Mini reviews in medicinal chemistry (01.01.2019)
Published in Mini reviews in medicinal chemistry (01.01.2019)
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The RAF-MEK-ERK pathway: targeting ERK to overcome obstacles to effective cancer therapy
Yu, Zutao, Ye, Shiqi, Hu, Gaoyun, Lv, Meng, Tu, Zhijun, Zhou, Kun, Li, Qianbin
Published in Future medicinal chemistry (01.03.2015)
Published in Future medicinal chemistry (01.03.2015)
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3,5-Disubstituted-thiazolidine-2,4-dione analogs as anticancer agents: Design, synthesis and biological characterization
Liu, Kai, Rao, Wei, Parikh, Hardik, Li, Qianbin, Guo, Tai L., Grant, Steven, Kellogg, Glen E., Zhang, Shijun
Published in European journal of medicinal chemistry (2012)
Published in European journal of medicinal chemistry (2012)
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Inhibitors of 11β-Hydroxylase (CYP11B1) for Treating Diseases Related to Excess Cortisol
Zhu, Weixing, Chen, Zhuo, Li, Qianbin, Tan, Guishan, Hu, Gaoyun
Published in Current medicinal chemistry (01.01.2016)
Published in Current medicinal chemistry (01.01.2016)
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A Novel PDK1/MEK Dual Inhibitor Induces Cytoprotective Autophagy via the PDK1/Akt Signaling Pathway in Non-Small Cell Lung Cancer
Liu, Rangru, Chen, Zhuo, Hu, Gaoyun, Yu, Zutao, Li, Qianbin, Liu, Danqi, Li, Ling, Liu, Zhaoqian
Published in Pharmaceuticals (Basel, Switzerland) (01.02.2023)
Published in Pharmaceuticals (Basel, Switzerland) (01.02.2023)
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Novel Pyrazolo[3,4-b] Pyridine Derivative (HLQ2g) Attenuates Hypoxic Pulmonary Hypertension via Restoring cGKI Expression and BMP Signaling Pathway
Li, Lijun, Yin, Minghui, Hu, Liqing, Tian, Xiaoting, He, Xiangrong, Zhao, Congke, Li, Ying, Li, Qianbin, Li, Xiaohui
Published in Frontiers in pharmacology (01.10.2021)
Published in Frontiers in pharmacology (01.10.2021)
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The Protective Effect of Fluorofenidone against Cyclosporine A-Induced Nephrotoxicity
Chen, Yang, Wang, Nasui, Yuan, Qiongjing, Qin, Jiao , Hu, Gaoyun, Li, Qianbin, Tao, Lijian , Xie, Yanyun , Peng, Zhangzhe
Published in Kidney & blood pressure research (01.08.2019)
Published in Kidney & blood pressure research (01.08.2019)
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Protective Effect of Fluorofenidone Against Acute Lung Injury Through Suppressing the MAPK/NF-κB Pathway
Lv, Xin, Yao, Tingting, He, Rongling, He, Yijun, Li, Mengyu, Han, Yuanyuan, Zhang, Yan, Long, Lingzhi, Jiang, Guoliang, Cheng, Xiaoyun, Xie, Yanyun, Huang, Ling, Peng, Zhangzhe, Hu, Gaoyun, Li, Qianbin, Tao, Lijian, Meng, Jie
Published in Frontiers in pharmacology (20.12.2021)
Published in Frontiers in pharmacology (20.12.2021)
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Soluble Guanylate Cyclase: A New Therapeutic Target for Fibrotic Diseases
Hu, Liqing, Wang, Zeyu, Yi, Rui, Yi, Honghong, Xiao, Sijia, Chen, Zhuo, Hu, Gaoyun, Li, Qianbin
Published in Current medicinal chemistry (01.01.2017)
Published in Current medicinal chemistry (01.01.2017)
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A novel dual MEK/PDK1 inhibitor 9za retards the cell cycle at G0/G1 phase and induces mitochondrial apoptosis in non-small cell lung cancer cells
Liu, Rangru, Yu, Zutao, Chen, Zhuo, Liu, Danqi, Huang, Fengying, Li, Qianbin, Hu, Gaoyun, Xinan Yi, Li, Xi, Zhou, Honghao, Liu, Zhaoqian
Published in PeerJ (San Francisco, CA) (02.10.2020)
Published in PeerJ (San Francisco, CA) (02.10.2020)
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Structure–activity relationship (SAR) studies of 3-(2-amino-ethyl)-5-(4-ethoxy-benzylidene)-thiazolidine-2,4-dione: Development of potential substrate-specific ERK1/2 inhibitors
Li, Qianbin, Al-Ayoubi, Adnan, Guo, Tailiang, Zheng, Hui, Sarkar, Aurijit, Nguyen, Tri, Eblen, Scott T., Grant, Steven, Kellogg, Glen E., Zhang, Shijun
Published in Bioorganic & medicinal chemistry letters (01.11.2009)
Published in Bioorganic & medicinal chemistry letters (01.11.2009)
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