Development of selective class I protein arginine methyltransferase inhibitors through fragment-based drug design approach
Bhattacharya, Debomita, Shi Ming Li, Alice, Paul, Barnali, Ghosh Dastidar, Uddipta, Santhakumar, Vijayaratnam, Sarkar, Dipika, Chau, Irene, Li, Fengling, Ghosh, Trisha, Vedadi, Masoud, Talukdar, Arindam
Published in European journal of medicinal chemistry (15.11.2023)
Published in European journal of medicinal chemistry (15.11.2023)
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Journal Article
Design and synthesis of naturally-inspired SARS-CoV-2 inhibitors
Hassan, Haitham, Chiavaralli, Jeanne, Hassan, Afnan, Bedda, Loay, Krischuns, Tim, Chen, Kuang-Yu, Li, Alice Shi Ming, Delpal, Adrien, Decroly, Etienne, Vedadi, Masoud, Naffakh, Nadia, Agou, Fabrice, Mallart, Sergio, Arafa, Reem K, Arimondo, Paola B
Published in MedChemComm (22.03.2023)
Published in MedChemComm (22.03.2023)
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Journal Article
Histone H4K20 monomethylation enables recombinant nucleosome methylation by PRMT1 in vitro
Li, Alice Shi Ming, Homsi, Charles, Bonneil, Eric, Thibault, Pierre, Verreault, Alain, Vedadi, Masoud
Published in Biochimica et biophysica acta. Gene regulatory mechanisms (01.06.2023)
Published in Biochimica et biophysica acta. Gene regulatory mechanisms (01.06.2023)
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Journal Article
SS148 and WZ16 inhibit the activities of nsp10-nsp16 complexes from all seven human pathogenic coronaviruses
Li, Fengling, Ghiabi, Pegah, Hajian, Taraneh, Klima, Martin, Li, Alice Shi Ming, Khalili Yazdi, Aliakbar, Chau, Irene, Loppnau, Peter, Kutera, Maria, Seitova, Almagul, Bolotokova, Albina, Hutchinson, Ashley, Perveen, Sumera, Boura, Evzen, Vedadi, Masoud
Published in Biochimica et biophysica acta. General subjects (01.04.2023)
Published in Biochimica et biophysica acta. General subjects (01.04.2023)
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Journal Article
Chemical probes for protein arginine methyltransferases
Li, Alice Shi Ming, Li, Fengling, Eram, Mohammad S., Bolotokova, Albina, dela Seña, Carlo C., Vedadi, Masoud
Published in Methods (San Diego, Calif.) (15.03.2020)
Published in Methods (San Diego, Calif.) (15.03.2020)
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Journal Article
Discovery of Nanomolar DCAF1 Small Molecule Ligands
Li, Alice Shi Ming, Kimani, Serah, Wilson, Brian, Noureldin, Mahmoud, González-Álvarez, Héctor, Mamai, Ahmed, Hoffer, Laurent, Guilinger, John P., Zhang, Ying, von Rechenberg, Moritz, Disch, Jeremy S., Mulhern, Christopher J., Slakman, Belinda L., Cuozzo, John W., Dong, Aiping, Poda, Gennady, Mohammed, Mohammed, Saraon, Punit, Mittal, Manish, Modh, Pratik, Rathod, Vaibhavi, Patel, Bhashant, Ackloo, Suzanne, Santhakumar, Vijayaratnam, Szewczyk, Magdalena M, Barsyte-Lovejoy, Dalia, Arrowsmith, Cheryl H., Marcellus, Richard, Guié, Marie-Aude, Keefe, Anthony D., Brown, Peter J., Halabelian, Levon, Al-awar, Rima, Vedadi, Masoud
Published in Journal of medicinal chemistry (13.04.2023)
Published in Journal of medicinal chemistry (13.04.2023)
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Journal Article
Enzymatic nucleosome acetylation selectively affects activity of histone methyltransferases in vitro
Trush, Viacheslav V., Feller, Christian, Li, Alice Shi Ming, Allali-Hassani, Abdellah, Szewczyk, Magdalena M., Chau, Irene, Eram, Mohammad S., Jiang, Boya, Luu, Raymond, Zhang, Fangfei, Barsyte-Lovejoy, Dalia, Aebersold, Ruedi, Arrowsmith, Cheryl H., Vedadi, Masoud
Published in Biochimica et biophysica acta. Gene regulatory mechanisms (01.07.2022)
Published in Biochimica et biophysica acta. Gene regulatory mechanisms (01.07.2022)
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Journal Article
Crystal structures of DCAF1-PROTAC-WDR5 ternary complexes provide insight into DCAF1 substrate specificity
Mabanglo, Mark F., Wilson, Brian, Noureldin, Mahmoud, Kimani, Serah W., Mamai, Ahmed, Krausser, Chiara, González-Álvarez, Héctor, Srivastava, Smriti, Mohammed, Mohammed, Hoffer, Laurent, Chan, Manuel, Avrumutsoae, Jamie, Li, Alice Shi Ming, Hajian, Taraneh, Tucker, Sarah, Green, Stuart, Szewczyk, Magdalena, Barsyte-Lovejoy, Dalia, Santhakumar, Vijayaratnam, Ackloo, Suzanne, Loppnau, Peter, Li, Yanjun, Seitova, Almagul, Kiyota, Taira, Wang, Jue George, Privé, Gilbert G., Kuntz, Douglas A., Patel, Bhashant, Rathod, Vaibhavi, Vala, Anand, Rout, Bhimsen, Aman, Ahmed, Poda, Gennady, Uehling, David, Ramnauth, Jailall, Halabelian, Levon, Marcellus, Richard, Al-awar, Rima, Vedadi, Masoud
Published in Nature communications (23.11.2024)
Published in Nature communications (23.11.2024)
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Journal Article
Discovery of a Druggable, Cryptic Pocket in SARS-CoV‑2 nsp16 Using Allosteric Inhibitors
Inniss, Nicole L., Kozic, Ján, Li, Fengling, Rosas-Lemus, Monica, Minasov, George, Rybáček, Jiří, Zhu, Yingjie, Pohl, Radek, Shuvalova, Ludmilla, Rulíšek, Lubomír, Brunzelle, Joseph S., Bednárová, Lucie, Štefek, Milan, Kormaník, Ján Michael, Andris, Erik, Šebestík, Jaroslav, Li, Alice Shi Ming, Brown, Peter J., Schmitz, Uli, Saikatendu, Kumar, Chang, Edcon, Nencka, Radim, Vedadi, Masoud, Satchell, Karla J. F.
Published in ACS infectious diseases (13.10.2023)
Published in ACS infectious diseases (13.10.2023)
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Journal Article
Rational Design of Highly Potent SARS-CoV‑2 nsp14 Methyltransferase Inhibitors
Štefek, Milan, Chalupská, Dominika, Chalupský, Karel, Zgarbová, Michala, Dvořáková, Alexandra, Krafčíková, Petra, Li, Alice Shi Ming, Šála, Michal, Dejmek, Milan, Otava, Tomáš, Chaloupecká, Ema, Kozák, Jaroslav, Kozic, Ján, Vedadi, Masoud, Weber, Jan, Mertlíková-Kaiserová, Helena, Nencka, Radim
Published in ACS omega (01.08.2023)
Published in ACS omega (01.08.2023)
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