Chimeric 2C10R4 anti-CD40 antibody therapy is critical for long-term survival of GTKO.hCD46.hTBM pig-to-primate cardiac xenograft
Mohiuddin, Muhammad M., Singh, Avneesh K., Corcoran, Philip C., Thomas III, Marvin L., Clark, Tannia, Lewis, Billeta G., Hoyt, Robert F., Eckhaus, Michael, Pierson III, Richard N., Belli, Aaron J., Wolf, Eckhard, Klymiuk, Nikolai, Phelps, Carol, Reimann, Keith A., Ayares, David, Horvath, Keith A.
Published in Nature communications (05.04.2016)
Published in Nature communications (05.04.2016)
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Journal Article
Circulating cell-free DNA as a biomarker of tissue injury: Assessment in a cardiac xenotransplantation model
Agbor-Enoh, Sean, Chan, Joshua L., Singh, Avneesh, Tunc, Ilker, Gorham, Sasha, Zhu, Jun, Pirooznia, Mehdi, Corcoran, Philip C., Thomas, Marvin L., Lewis, Billeta G.T., Jang, Moon Kyoo, Ayares, David L., Horvath, Keith A., Mohiuddin, Muhammad M., Valantine, Hannah
Published in The Journal of heart and lung transplantation (01.08.2018)
Published in The Journal of heart and lung transplantation (01.08.2018)
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Journal Article
Cardiac xenografts show reduced survival in the absence of transgenic human thrombomodulin expression in donor pigs
Singh, Avneesh K., Chan, Joshua L., DiChiacchio, Laura, Hardy, Naomi L., Corcoran, Philip C., Lewis, Billeta G. T., Thomas, Marvin L., Burke, Allen P., Ayares, David, Horvath, Keith A., Mohiuddin, Muhammad M.
Published in Xenotransplantation (Københaven) (01.03.2019)
Published in Xenotransplantation (Københaven) (01.03.2019)
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Journal Article
Role of anti-CD40 antibody-mediated costimulation blockade on non-Gal antibody production and heterotopic cardiac xenograft survival in a GTKO.hCD46Tg pig-to-baboon model
Mohiuddin, Muhammad M., Singh, Avneesh K., Corcoran, Philip C., Hoyt, Robert F., Thomas III, Marvin L., Lewis, Billeta G. T., Eckhaus, Michael, Dabkowski, Nicole L., Belli, Aaron J., Reimann, Keith A., Ayares, David, Horvath, Keith A.
Published in Xenotransplantation (Københaven) (01.01.2014)
Published in Xenotransplantation (Københaven) (01.01.2014)
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Journal Article
Heterotopic Porcine Cardiac Xenotransplantation in the Intra-Abdominal Position in a Non-Human Primate Model
Goerlich, Corbin E., DiChiacchio, Laura, Zhang, Tianshu, Singh, Avneesh K., Lewis, Billeta, Tatarov, Ivan, Hershfeld, Alena, Sentz, Faith, Ayares, David, Corcoran, Philip, Horvath, Keith, Mohiuddin, Muhammad M.
Published in Scientific reports (01.07.2020)
Published in Scientific reports (01.07.2020)
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Journal Article
Encouraging experience using multi‐transgenic xenografts in a pig‐to‐baboon cardiac xenotransplantation model
Chan, Joshua L., Singh, Avneesh K., Corcoran, Philip C., Thomas, Marvin L., Lewis, Billeta GT, Ayares, David L., Vaught, Todd, Horvath, Keith A., Mohiuddin, Muhammad M.
Published in Xenotransplantation (Københaven) (01.11.2017)
Published in Xenotransplantation (Københaven) (01.11.2017)
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Journal Article
Blood Cardioplegia Induction, Perfusion Storage and Graft Dysfunction in Cardiac Xenotransplantation
Goerlich, Corbin E, Griffith, Bartley, Singh, Avneesh K, Abdullah, Mohamed, Singireddy, Shreya, Kolesnik, Irina, Lewis, Billeta, Sentz, Faith, Tatarov, Ivan, Hershfeld, Alena, Zhang, Tianshu, Strauss, Erik, Odonkor, Patrick, Williams, Brittney, Tabatabai, Ali, Bhutta, Adnan, Ayares, David, Kaczorowski, David J, Mohiuddin, Muhammad M
Published in Frontiers in immunology (09.06.2021)
Published in Frontiers in immunology (09.06.2021)
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Journal Article
Intra-Abdominal Heterotopic Cardiac Xenotransplantation: Pearls and Pitfalls
DiChiacchio, Laura, Singh, Avneesh K, Chan, Joshua L, Shockcor, Nicole M, Zhang, Tianshu, Lewis, Billeta G, Ayares, David, Corcoran, Philip, Horvath, Keith A, Mohiuddin, Muhammad M
Published in Frontiers in cardiovascular medicine (25.07.2019)
Published in Frontiers in cardiovascular medicine (25.07.2019)
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Journal Article
CD4+CD25HiFoxP3+ regulatory T cells in long‐term cardiac xenotransplantation
Singh, Avneesh K., Chan, Joshua L., Seavey, Caleb N., Corcoran, Philip C., Hoyt, Robert F., Lewis, Billeta G.T., Thomas, Marvin L., Ayares, David L., Horvath, Keith A., Mohiuddin, Muhammad M.
Published in Xenotransplantation (Københaven) (01.03.2018)
Published in Xenotransplantation (Københaven) (01.03.2018)
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Journal Article
Graft dysfunction in compassionate use of genetically engineered pig-to-human cardiac xenotransplantation: a case report
Mohiuddin, Muhammad M, Singh, Avneesh K, Scobie, Linda, Goerlich, Corbin E, Grazioli, Alison, Saharia, Kapil, Crossan, Claire, Burke, Allen, Drachenberg, Cinthia, Oguz, Cihan, Zhang, Tianshu, Lewis, Billeta, Hershfeld, Alena, Sentz, Faith, Tatarov, Ivan, Mudd, Sarah, Braileanu, Gheorghe, Rice, Kathryn, Paolini, John F, Bondensgaard, Kent, Vaught, Todd, Kuravi, Kasinath, Sorrells, Lori, Dandro, Amy, Ayares, David, Lau, Christine, Griffith, Bartley P
Published in The Lancet (British edition) (29.07.2023)
Published in The Lancet (British edition) (29.07.2023)
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Journal Article
Progressive genetic modifications of porcine cardiac xenografts extend survival to 9 months
Mohiuddin, Muhammad M., Goerlich, Corbin E., Singh, Avneesh K., Zhang, Tianshu, Tatarov, Ivan, Lewis, Billeta, Sentz, Faith, Hershfeld, Alena, Braileanu, Gheorghe, Odonkor, Patrick, Strauss, Erik, Williams, Brittney, Burke, Allen, Hittman, Jamie, Bhutta, Adnan, Tabatabai, Ali, Gupta, Anuj, Vaught, Todd, Sorrells, Lori, Kuravi, Kasinath, Dandro, Amy, Eyestone, Will, Kaczorowski, David J., Ayares, David, Griffith, Bartley P.
Published in Xenotransplantation (Københaven) (01.05.2022)
Published in Xenotransplantation (Københaven) (01.05.2022)
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Journal Article
A Standardized Approach to Orthotopic (Life-supporting) Porcine Cardiac Xenotransplantation in a Nonhuman Primate Model
Goerlich, Corbin E, Griffith, Bartley P, Shah, Aakash, Treffalls, John A, Zhang, Tianshu, Lewis, Billeta, Tatarov, Ivan, Hershfeld, Alena, Sentz, Faith, Braileanu, Gheorghe, Ayares, David, Singh, Avneesh K, Mohiuddin, Muhammad M
Published in Transplantation (01.08.2023)
Published in Transplantation (01.08.2023)
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Journal Article
Compassionate Use of Genetically Engineered Pig Cardiac Xenotransplantation in a Human: What caused graft dysfunction?
Mohiuddin, Muhammad M, Singh, Avneesh K, Scobie, Linda, Goerlich, Corbin E., Grazioli, Alison, Saharia, Kapil, Crossan, Claire, Burke, Allen, Drachenberg, Cinthia, Oguz, Cihan, Zhang, Tianshu, Lewis, Billeta, Hershfeld, Alena, Sentz, Faith, Tatarov, Ivan, Mudd, Sarah, Braileanu, Gheorghe, Rice, Kathryn, Paolini, John F., Bondensgaard, Kent, Vaught, Todd, Kuravi, Kasinath, Sorrells, Lori, Dandro, Amy, Ayares, David, Lau, Christine, Griffith, Bartley P
Published in The Lancet (British edition) (29.06.2023)
Published in The Lancet (British edition) (29.06.2023)
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Journal Article
Early Experience With Preclinical Perioperative Cardiac Xenograft Dysfunction in a Single Program
DiChiacchio, Laura, Singh, Avneesh K., Lewis, Billeta, Zhang, Tianshu, Hardy, Naomi, Pasrija, Chetan, Morales, David, Odonkor, Patrick, Strauss, Erik, Williams, Brittney, Deatrick, Kristopher B., Kaczorowski, David J., Ayares, David, Griffith, Bartley P., Bartlett, Stephen T., Mohiuddin, Muhammad M.
Published in The Annals of thoracic surgery (01.05.2020)
Published in The Annals of thoracic surgery (01.05.2020)
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Journal Article
One‐Year Heterotopic Cardiac Xenograft Survival in a Pig to Baboon Model
Mohiuddin, M. M., Singh, A. K., Corcoran, P. C., Hoyt, R. F., Thomas, M. L., Lewis, B. G. T., Eckhaus, M., Reimann, K. A., Klymiuk, N., Wolf, E., Ayares, D., Horvath, K. A.
Published in American journal of transplantation (01.02.2014)
Published in American journal of transplantation (01.02.2014)
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Journal Article
Early experience with preclinical peri-operative cardiac xenograft dysfunction in a single program
DiChiacchio, Laura, Singh, Avneesh K., Lewis, Billeta, Zhang, Tianshu, Hardy, Naomi, Pasrija, Chetan, Morales, David, Odonkor, Patrick, Strauss, Erik, Williams, Brittney, Deatrick, Kistopher B., Kaczorowski, David J., Ayares, David, Griffith, Bartley P., Bartlett, Stephen T., Mohiuddin, Muhammad M.
Published in The Annals of thoracic surgery (04.10.2019)
Published in The Annals of thoracic surgery (04.10.2019)
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Journal Article
CD 4+ CD 25 Hi FoxP3+ regulatory T cells in long‐term cardiac xenotransplantation
Singh, Avneesh K., Chan, Joshua L., Seavey, Caleb N., Corcoran, Philip C., Hoyt, Robert F., Lewis, Billeta G.T., Thomas, Marvin L., Ayares, David L., Horvath, Keith A., Mohiuddin, Muhammad M.
Published in Xenotransplantation (Københaven) (01.03.2018)
Published in Xenotransplantation (Københaven) (01.03.2018)
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Journal Article
CD4+CD25 Hi FoxP3+ regulatory T cells in long-term cardiac xenotransplantation
Singh, Avneesh K, Chan, Joshua L, Seavey, Caleb N, Corcoran, Philip C, Hoyt, Jr, Robert F, Lewis, Billeta G T, Thomas, Marvin L, Ayares, David L, Horvath, Keith A, Mohiuddin, Muhammad M
Published in Xenotransplantation (Københaven) (01.03.2018)
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Published in Xenotransplantation (Københaven) (01.03.2018)
Journal Article
CD4+CD25Hi FoxP3+ regulatory T cells in long-term cardiac xenotransplantation
Singh, Avneesh K, Chan, Joshua L, Seavey, Caleb N, Corcoran, Philip C, Hoyt, Robert F, Lewis, Billeta G T, Thomas, Marvin L, Ayares, David L, Horvath, Keith A, Mohiuddin, Muhammad M
Published in Xenotransplantation (Københaven) (01.03.2018)
Published in Xenotransplantation (Københaven) (01.03.2018)
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Journal Article