Diversification of TAM receptor tyrosine kinase function
Zagórska, Anna, Través, Paqui G, Lew, Erin D, Dransfield, Ian, Lemke, Greg
Published in Nature immunology (01.10.2014)
Published in Nature immunology (01.10.2014)
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Journal Article
Differential TAM receptor-ligand-phospholipid interactions delimit differential TAM bioactivities
Lew, Erin D, Oh, Jennifer, Burrola, Patrick G, Lax, Irit, Zagórska, Anna, Través, Paqui G, Schlessinger, Joseph, Lemke, Greg
Published in eLife (29.09.2014)
Published in eLife (29.09.2014)
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Journal Article
Enveloped Viruses Disable Innate Immune Responses in Dendritic Cells by Direct Activation of TAM Receptors
Bhattacharyya, Suchita, Zagórska, Anna, Lew, Erin D., Shrestha, Bimmi, Rothlin, Carla V., Naughton, John, Diamond, Michael S., Lemke, Greg, Young, John A.T.
Published in Cell host & microbe (14.08.2013)
Published in Cell host & microbe (14.08.2013)
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Journal Article
Autophosphorylation of FGFR1 Kinase Is Mediated by a Sequential and Precisely Ordered Reaction
Furdui, Cristina M., Lew, Erin D., Schlessinger, Joseph, Anderson, Karen S.
Published in Molecular cell (03.03.2006)
Published in Molecular cell (03.03.2006)
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Journal Article
Mutations in different components of FGF signaling in LADD syndrome
Wollnik, Bernd, Rohmann, Edyta, Brunner, Han G, Kayserili, Hülya, Uyguner, Oya, Nürnberg, Gudrun, Lew, Erin D, Dobbie, Angus, Eswarakumar, Veraragavan P, Uzumcu, Abdullah, Ulubil-Emeroglu, Melike, Leroy, Jules G, Li, Yun, Becker, Christian, Lehnerdt, Kai, Cremers, Cor W R J, Yüksel-Apak, Memnune, Nürnberg, Peter, Kubisch, Christian, Schlessinger, Joseph, van Bokhoven, Hans
Published in Nature genetics (01.04.2006)
Published in Nature genetics (01.04.2006)
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Journal Article
TAM receptors regulate multiple features of microglial physiology
Fourgeaud, Lawrence, Través, Paqui G., Tufail, Yusuf, Leal-Bailey, Humberto, Lew, Erin D., Burrola, Patrick G., Callaway, Perri, Zagórska, Anna, Rothlin, Carla V., Nimmerjahn, Axel, Lemke, Greg
Published in Nature (London) (14.04.2016)
Published in Nature (London) (14.04.2016)
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Journal Article
Lacrimo-Auriculo-Dento-Digital Syndrome Is Caused by Reduced Activity of the Fibroblast Growth Factor 10 (FGF10)-FGF Receptor 2 Signaling Pathway
Shams, Imad, Rohmann, Edyta, Eswarakumar, Veraragavan P., Lew, Erin D., Yuzawa, Satoru, Wollnik, Bernd, Schlessinger, Joseph, Lax, Irit
Published in Molecular and Cellular Biology (01.10.2007)
Published in Molecular and Cellular Biology (01.10.2007)
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Journal Article
Structural basis for reduced FGFR2 activity in LADD syndrome: Implications for FGFR autoinhibition and activation
Lew, Erin D, Bae, Jae Hyun, Rohmann, Edyta, Wollnik, Bernd, Schlessinger, Joseph
Published in Proceedings of the National Academy of Sciences - PNAS (11.12.2007)
Published in Proceedings of the National Academy of Sciences - PNAS (11.12.2007)
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Journal Article
Immuno-oncological Efficacy of RXDX-106, a Novel TAM (TYRO3, AXL, MER) Family Small-Molecule Kinase Inhibitor
Yokoyama, Yumi, Lew, Erin D, Seelige, Ruth, Tindall, Elizabeth A, Walsh, Colin, Fagan, Patrick C, Lee, Jack Y, Nevarez, Robin, Oh, Joanne, Tucker, Kathleen D, Chen, Marissa, Diliberto, Amy, Vaaler, Heather, Smith, Kristen M, Albert, Amanda, Li, Gary, Bui, Jack D
Published in Cancer research (Chicago, Ill.) (15.04.2019)
Published in Cancer research (Chicago, Ill.) (15.04.2019)
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Journal Article
The TAM receptor Mertk protects against neuroinvasive viral infection by maintaining blood-brain barrier integrity
Miner, Jonathan J, Daniels, Brian P, Shrestha, Bimmi, Proenca-Modena, Jose L, Lew, Erin D, Lazear, Helen M, Gorman, Matthew J, Lemke, Greg, Klein, Robyn S, Diamond, Michael S
Published in Nature medicine (01.12.2015)
Published in Nature medicine (01.12.2015)
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Journal Article
Abstract 335: In situ protein complexes as a measure of AXL signaling and inhibitor response in cell line models of lung cancer
Majumder, Anurima, Bai, Yun, Kinose, Fumi, Lew, Erin D., Yokoyama, Yumi, Murphy, Danielle, Li, Gary, Haura, Eric B.
Published in Cancer research (Chicago, Ill.) (01.07.2017)
Published in Cancer research (Chicago, Ill.) (01.07.2017)
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Journal Article
Abstract 4698: Immuno-oncological efficacy of RXDX-106, a novel, selective and potent small molecule TAM (TYRO3, AXL, MER) inhibitor
Yokoyama, Yumi, Lew, Erin D., Seelige, Ruth, Walsh, Colin, Barrera, Maria, Tindall, Elizabeth, Oh, Joanne, Ely, Heather, Diliberto, Amy, Albert, Amanda, Bui, Jack, Li, Gary
Published in Cancer research (Chicago, Ill.) (01.07.2017)
Published in Cancer research (Chicago, Ill.) (01.07.2017)
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Journal Article
Abstract 4191: RXDX-106, a novel, selective and potent small molecule TAM (TYRO3, AXL, MER) inhibitor, demonstrates efficacy in TAM-driven tumors
Lew, Erin D., Tindall, Elizabeth A., Oh, Joanne, Walsh, Colin, Barrera, Maria, Ely, Heather, Diliberto, Amy, Yokoyama, Yumi, Li, Gary, Albert, Amanda
Published in Cancer research (Chicago, Ill.) (01.07.2017)
Published in Cancer research (Chicago, Ill.) (01.07.2017)
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Journal Article
Abstract 3771: Mechanistic and pharmacodynamic characterization of the immuno-oncological activity of RXDX-106, a novel TYRO3, AXL, and MER (TAM) inhibitor in clinical development
Albert, Amanda, Lew, Erin D., Smith, Kristen, Tindall, Elizabeth A., Yokoyama, Yumi, Diliberto, Amy, Ely, Heather, Lee, Jack, Nevarez, Robin, Oh, Joanne, Walsh, Colin, Christiansen, Jason, Li, Gary, Shoemaker, Robert
Published in Cancer research (Chicago, Ill.) (01.07.2018)
Published in Cancer research (Chicago, Ill.) (01.07.2018)
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Journal Article
Diversification of TAM receptor function
Zagórska, Anna, Través, Paqui G., Lew, Erin D., Dransfield, Ian, Lemke, Greg
Published in Nature immunology (07.09.2014)
Published in Nature immunology (07.09.2014)
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Journal Article
Abstract 2669: ERAS-007 (ERK inhibitor) + ERAS-601 (SHP2 inhibitor) exhibit nonclinical combination activity across KRAS mutated NSCLC, CRC, and PDAC tumor models
Martin, Leenus, Lew, Erin D., Patel, Roopal, Oh, Joanne, Zhang, Jingchuan, Nevarez, Robin, Congdon, Taylor, Lin, Wei, Brail, Les, Shoemaker, Robert
Published in Cancer research (Chicago, Ill.) (15.06.2022)
Published in Cancer research (Chicago, Ill.) (15.06.2022)
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