Emicizumab Prophylaxis in Patients Who Have Hemophilia A without Inhibitors
Mahlangu, Johnny, Oldenburg, Johannes, Paz-Priel, Ido, Negrier, Claude, Niggli, Markus, Mancuso, M. Elisa, Schmitt, Christophe, Jiménez-Yuste, Victor, Kempton, Christine, Dhalluin, Christophe, Callaghan, Michael U, Bujan, Willem, Shima, Midori, Adamkewicz, Joanne I, Asikanius, Elina, Levy, Gallia G, Kruse-Jarres, Rebecca
Published in The New England journal of medicine (30.08.2018)
Published in The New England journal of medicine (30.08.2018)
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A Pharmacometric Approach to Substitute for a Conventional Dose-Finding Study in Rare Diseases: Example of Phase III Dose Selection for Emicizumab in Hemophilia A
Yoneyama, Koichiro, Schmitt, Christophe, Kotani, Naoki, Levy, Gallia G., Kasai, Ryu, Iida, Satofumi, Shima, Midori, Kawanishi, Takehiko
Published in Clinical pharmacokinetics (01.09.2018)
Published in Clinical pharmacokinetics (01.09.2018)
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Mutations in a member of the ADAMTS gene family cause thrombotic thrombocytopenic purpura
Ginsburg, David, Levy, Gallia G, Nichols, William C, Lian, Eric C, Foroud, Tatiana, McClintick, Jeanette N, McGee, Beth M, Yang, Angela Y, Siemieniak, David R, Stark, Kenneth R, Gruppo, Ralph, Sarode, Ravindra, Shurin, Susan B, Chandrasekaran, Visalam, Stabler, Sally P, Sabio, Hernan, Bouhassira, Eric E, Upshaw, Jefferson D, Tsai, Han-Mou
Published in Nature (London) (04.10.2001)
Published in Nature (London) (04.10.2001)
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Untreated bleeds in people with hemophilia A in a noninterventional study and intrapatient comparison after initiating emicizumab in HAVEN 1–3
Callaghan, Michael U., Asikanius, Elina, Lehle, Michaela, Oldenburg, Johannes, Mahlangu, Johnny, Uguen, Marianne, Chebon, Sammy, Kruse‐Jarres, Rebecca, Jiménez‐Yuste, Víctor, Shima, Midori, Trask, Peter, Kempton, Christine L., Kessler, Craig M., Levy, Gallia G., Peyvandi, Flora
Published in Research and practice in thrombosis and haemostasis (01.08.2022)
Published in Research and practice in thrombosis and haemostasis (01.08.2022)
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Emicizumab Prophylaxis in Hemophilia A with Inhibitors
Oldenburg, Johannes, Mahlangu, Johnny N, Kim, Benjamin, Schmitt, Christophe, Callaghan, Michael U, Young, Guy, Santagostino, Elena, Kruse-Jarres, Rebecca, Negrier, Claude, Kessler, Craig, Valente, Nancy, Asikanius, Elina, Levy, Gallia G, Windyga, Jerzy, Shima, Midori
Published in The New England journal of medicine (31.08.2017)
Published in The New England journal of medicine (31.08.2017)
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A multicenter, open-label phase 3 study of emicizumab prophylaxis in children with hemophilia A with inhibitors
Young, Guy, Liesner, Ri, Chang, Tiffany, Sidonio, Robert, Oldenburg, Johannes, Jiménez-Yuste, Victor, Mahlangu, Johnny, Kruse-Jarres, Rebecca, Wang, Michael, Uguen, Marianne, Doral, Michelle Y., Wright, Lilyan Y., Schmitt, Christophe, Levy, Gallia G., Shima, Midori, Mancuso, Maria Elisa
Published in Blood (12.12.2019)
Published in Blood (12.12.2019)
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Journal Article
Long-term outcomes with emicizumab prophylaxis for hemophilia A with or without FVIII inhibitors from the HAVEN 1-4 studies
Callaghan, Michael U., Negrier, Claude, Paz-Priel, Ido, Chang, Tiffany, Chebon, Sammy, Lehle, Michaela, Mahlangu, Johnny, Young, Guy, Kruse-Jarres, Rebecca, Mancuso, Maria Elisa, Niggli, Markus, Howard, Monet, Bienz, Nives Selak, Shima, Midori, Jiménez-Yuste, Victor, Schmitt, Christophe, Asikanius, Elina, Levy, Gallia G., Pipe, Steven W., Oldenburg, Johannes
Published in Blood (22.04.2021)
Published in Blood (22.04.2021)
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Sialyltransferase ST3Gal-IV Operates as a Dominant Modifier of Hemostasis by Concealing Asialoglycoprotein Receptor Ligands
Ellies, Lesley G., Ditto, David, Levy, Gallia G., Wahrenbrock, Mark, Ginsburg, David, Varki, Ajit, Le, Dzung T., Marth, Jamey D.
Published in Proceedings of the National Academy of Sciences - PNAS (23.07.2002)
Published in Proceedings of the National Academy of Sciences - PNAS (23.07.2002)
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Pharmacokinetics and Pharmacodynamics of Emicizumab in Persons with Hemophilia A with Factor VIII Inhibitors: HAVEN 1 Study
Schmitt, Christophe, Adamkewicz, Joanne I., Xu, Jin, Petry, Claire, Catalani, Olivier, Young, Guy, Negrier, Claude, Callaghan, Michael U., Levy, Gallia G.
Published in Thrombosis and haemostasis (01.03.2021)
Published in Thrombosis and haemostasis (01.03.2021)
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Safety analysis of rFVIIa with emicizumab dosing in congenital hemophilia A with inhibitors: Experience from the HAVEN clinical program
Levy, Gallia G., Asikanius, Elina, Kuebler, Peter, Benchikh El Fegoun, Soraya, Esbjerg, Sille, Seremetis, Stephanie
Published in Journal of thrombosis and haemostasis (01.09.2019)
Published in Journal of thrombosis and haemostasis (01.09.2019)
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Journal Article
Efficacy, safety, and pharmacokinetics of emicizumab prophylaxis given every 4 weeks in people with haemophilia A (HAVEN 4): a multicentre, open-label, non-randomised phase 3 study
Pipe, Steven W, Shima, Midori, Lehle, Michaela, Shapiro, Amy, Chebon, Sammy, Fukutake, Katsuyuki, Key, Nigel S, Portron, Agnès, Schmitt, Christophe, Podolak-Dawidziak, Maria, Selak Bienz, Nives, Hermans, Cedric, Campinha-Bacote, Avrita, Kiialainen, Anna, Peerlinck, Kathelijne, Levy, Gallia G, Jiménez-Yuste, Victor
Published in The Lancet. Haematology (01.06.2019)
Published in The Lancet. Haematology (01.06.2019)
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A Model‐Based Framework to Inform the Dose Selection and Study Design of Emicizumab for Pediatric Patients With Hemophilia A
Yoneyama, Koichiro, Schmitt, Christophe, Chang, Tiffany, Dhalluin, Christophe, Nagami, Sayaka, Petry, Claire, Levy, Gallia G.
Published in Journal of clinical pharmacology (01.02.2022)
Published in Journal of clinical pharmacology (01.02.2022)
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Journal Article
Effect of emicizumab prophylaxis on bone and joint health markers in people with haemophilia A without factor VIII inhibitors in the HAVEN 3 study
Kiialainen, Anna, Niggli, Markus, Kempton, Christine L., Castaman, Giancarlo, Chang, Tiffany, Paz‐Priel, Ido, Adamkewicz, Joanne I., Levy, Gallia G.
Published in Haemophilia : the official journal of the World Federation of Hemophilia (01.11.2022)
Published in Haemophilia : the official journal of the World Federation of Hemophilia (01.11.2022)
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The effect of emicizumab prophylaxis on long‐term, self‐reported physical health in persons with haemophilia A without factor VIII inhibitors in the HAVEN 3 and HAVEN 4 studies
Skinner, Mark W., Négrier, Claude, Paz‐Priel, Ido, Chebon, Sammy, Jiménez‐Yuste, Victor, Callaghan, Michael U., Lehle, Michaela, Niggli, Markus, Mahlangu, Johnny, Shapiro, Amy, Shima, Midori, Campinha‐Bacote, Avrita, Levy, Gallia G., Oldenburg, Johannes, Mackensen, Sylvia, Pipe, Steven W.
Published in Haemophilia : the official journal of the World Federation of Hemophilia (01.09.2021)
Published in Haemophilia : the official journal of the World Federation of Hemophilia (01.09.2021)
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Journal Article
Health‐related quality of life and health status in persons with haemophilia A with inhibitors: A prospective, multicentre, non‐interventional study (NIS)
Mahlangu, Johnny, Oldenburg, Johannes, Callaghan, Michael U., Shima, Midori, Mancuso, Maria Elisa, Trask, Peter, Recht, Michael, Garcia, Claudia, Yang, Renchi, Lehle, Michaela, Macharia, Harrison, Asikanius, Elina, Levy, Gallia G., Kruse‐Jarres, Rebecca, von Mackensen, Sylvia
Published in Haemophilia : the official journal of the World Federation of Hemophilia (01.05.2019)
Published in Haemophilia : the official journal of the World Federation of Hemophilia (01.05.2019)
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Outcomes in children with hemophilia A with inhibitors: Results from a noninterventional study
Oldenburg, Johannes, Shima, Midori, Kruse‐Jarres, Rebecca, Santagostino, Elena, Mahlangu, Johnny, Lehle, Michaela, Selak Bienz, Nives, Chebon, Sammy, Asikanius, Elina, Trask, Peter, Mancuso, Maria Elisa, Jiménez‐Yuste, Victor, Mackensen, Sylvia, Levy, Gallia G.
Published in Pediatric blood & cancer (01.10.2020)
Published in Pediatric blood & cancer (01.10.2020)
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Bleeding events and safety outcomes in persons with haemophilia A with inhibitors: A prospective, multi‐centre, non‐interventional study
Mahlangu, Johnny, Oldenburg, Johannes, Callaghan, Michael U., Shima, Midori, Santagostino, Elena, Moore, Maggie, Recht, Michael, Garcia, Claudia, Yang, Renchi, Lehle, Michaela, Macharia, Harrison, Asikanius, Elina, Levy, Gallia G., Kruse‐Jarres, Rebecca
Published in Haemophilia : the official journal of the World Federation of Hemophilia (01.11.2018)
Published in Haemophilia : the official journal of the World Federation of Hemophilia (01.11.2018)
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A phase 2 PK/PD study of andexanet alfa for reversal of rivaroxaban and edoxaban anticoagulation in healthy volunteers
Lu, Genmin, Conley, Pamela B., Leeds, Janet M., Karbarz, Mark J., Levy, Gallia G., Mathur, Vandana S., Castillo, Janice, Crowther, Mark, Curnutte, John T.
Published in Blood advances (25.02.2020)
Published in Blood advances (25.02.2020)
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