Oral Monotherapy with Iptacopan, a Proximal Complement Inhibitor of Factor B, Has Superior Efficacy to Intravenous Terminal Complement Inhibition with Standard of Care Eculizumab or Ravulizumab and Favorable Safety in Patients with Paroxysmal Nocturnal Hemoglobinuria and Residual Anemia: Results from the Randomized, Active-Comparator-Controlled, Open-Label, Multicenter, Phase III Apply-PNH Study
Peffault de Latour, Regis, Roeth, Alexander, Kulasekararaj, Austin, Scheinberg, Phillip, Ueda, Yasutaka, de Castro, Carlos M, Di Bona, Eros, Schrezenmeier, Hubert, Langemeijer, Saskia MC, Barcellini, Wilma, Tavitian, Suzanne, Panse, Jens, Schafhausen, Philippe, Mauad, Vitor AQ, Kerloeguen, Cecile, Levitch, Rafael, Kumar, Rakesh, Thorburn, Christine, Maitra, Samopriyo, Dahlke, Marion, Risitano, Antonio M
Published in Blood (06.12.2022)
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Published in Blood (06.12.2022)
Journal Article
Oral Monotherapy with Iptacopan, a Proximal Complement Inhibitor of Factor B, Has Superior Efficacy to Intravenous Terminal Complement Inhibition with Standard of Care Eculizumab or Ravulizumab and Favorable Safety in Patients with Paroxysmal Nocturnal Hemoglobinuria and Residual Anemia: Results from the Randomized, Active-Comparator-Controlled, Open-Label, Multicenter, Phase III Apply-PNH Study
Peffault de Latour, Regis, Roeth, Alexander, Kulasekararaj, Austin, Scheinberg, Phillip, Ueda, Yasutaka, de Castro, Carlos M, Di Bona, Eros, Schrezenmeier, Hubert, Langemeijer, Saskia MC, Barcellini, Wilma, Tavitian, Suzanne, Panse, Jens, Schafhausen, Philippe, Mauad, Vitor AQ, Kerloeguen, Cecile, Levitch, Rafael, Kumar, Rakesh, Thorburn, Christine, Maitra, Samopriyo, Dahlke, Marion, Risitano, Antonio M
Published in Blood (06.12.2022)
Published in Blood (06.12.2022)
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Journal Article
Efficacy and safety of MAS825 (anti-IL-1β/IL-18) in COVID-19 patients with pneumonia and impaired respiratory function
Hakim, Alex D, Awili, Mustafa, O’Neal, Hollis R, Siddiqi, Omar, Jaffrani, Naseem, Lee, Richard, Overcash, Jeffrey S, Chauffe, Ann, Hammond, Terese C, Patel, Bela, Waters, Michael, Criner, Gerard J, Pachori, Alok, Junge, Guido, Levitch, Rafael, Watts, Jen, Koo, Philip, Sengupta, Tirtha, Yu, Lili, Kiffe, Michael, Pinck, Anne, Stein, Richard R, Bendrick-Peart, Jamie, Jenkins, Janet, Rowlands, Marianna, Waldron-Lynch, Frank, Matthews, Jesse
Published in Clinical and experimental immunology (13.10.2023)
Published in Clinical and experimental immunology (13.10.2023)
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Journal Article
Poster: CT-118: PH3 Study of Efficacy and Safety of Iptacopan (LNP023), an Oral Complement Factor B Inhibitor, in Patients with Paroxysmal Nocturnal Hemoglobinuria and Residual Anemia Despite Anti-C5 Antibody Treatment
Risitano, Antonio M., Kulasekararaj, Austin, De Castro, Carlos M., Scheinberg, Phillip, Levitch, Rafael, Bermann, Georgina, Dahlke, Marion, De Latour, Régis Peffault
Published in Clinical lymphoma, myeloma and leukemia (01.09.2021)
Published in Clinical lymphoma, myeloma and leukemia (01.09.2021)
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Journal Article
CT-118: PH3 Study of Efficacy and Safety of Iptacopan (LNP023), an Oral Complement Factor B Inhibitor, in Patients with Paroxysmal Nocturnal Hemoglobinuria and Residual Anemia Despite Anti-C5 Antibody Treatment
Risitano, Antonio M., Kulasekararaj, Austin, De Castro, Carlos M., Scheinberg, Phillip, Levitch, Rafael, Bermann, Georgina, Dahlke, Marion, de Latour, Régis Peffault
Published in Clinical lymphoma, myeloma and leukemia (01.09.2021)
Published in Clinical lymphoma, myeloma and leukemia (01.09.2021)
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Journal Article