Impact of CAR T-cell product viability on B-cell lymphoid malignancy outcomes
Chong, E.A, Schuster, S, Grupp, S, Davis, M.M, Siegel, D, Maude, S, Gladney, W, Frey, N, Porter, D, June, C, Levine, B.L
Published in Cytotherapy (Oxford, England) (01.05.2019)
Published in Cytotherapy (Oxford, England) (01.05.2019)
Get full text
Journal Article
Robust automated cell counter and viability measurement for engineered T cell product release
Ohayon, Y, Corl, C.M, Leskowitz, R.M, Malykhin, A, Arostegui, S.M, Hennesy, N.A, Ngo, S, Levine, B.L, Siegel, D, Fesnak, A, Davis, M.M
Published in Cytotherapy (Oxford, England) (01.05.2018)
Published in Cytotherapy (Oxford, England) (01.05.2018)
Get full text
Journal Article
Myeloid derived suppressor cells (MDSCS) reduce the manufacturing feasibilty of gene modified T cells
Gohil, M, Dai, A, Mackey, S, Negorev, D, Hennesy, N.A, O'Rourke, M, Lamontagne, A, Holland, D, Leskowitz, R.M, Xu, J, Ozerova, M, McKee, J.S, Pequignot, E, Siegel, D, Schuster, S, Svoboda, J, Garfall, A, Cohen, A, Stadtmauer, E, Gladney, W, Levine, B.L, Fraietta, J.A, Davis, M.M
Published in Cytotherapy (Oxford, England) (01.05.2019)
Published in Cytotherapy (Oxford, England) (01.05.2019)
Get full text
Journal Article
Successful Technology Transfer of Chimeric Antigen Receptor (CAR) Targeting CD19 (CTL019) Cell Processing From Academia to Industry Enables Scale-Up to Support Global Clinical Trials
Levine, B.L, Boyd, J, Jinivizian, K, Jeschke, M, Suhoski Davis, M.M, Zheng, Z, Stark, D, Keir, C, Wood, P
Published in Cytotherapy (Oxford, England) (01.06.2016)
Published in Cytotherapy (Oxford, England) (01.06.2016)
Get full text
Journal Article
Predictors of manufacturing (MFG) success for chimeric antigen receptor (CAR) T cells in Non-Hodgkin Lymphoma (NHL)
Davis, M.M, Fesnak, A, Leskowitz, R.M, McKee, J.S, Ohayon, Y, Corl, C.M, Malykhin, A, Fraietta, J.A, Joseph Melenhorst, J, June, C, Schuster, S, Levine, B.L
Published in Cytotherapy (Oxford, England) (01.05.2017)
Published in Cytotherapy (Oxford, England) (01.05.2017)
Get full text
Journal Article
Humanized chimeric antigen receptor (CAR)-modified T cells targeting CD19 induce remissions in children and young adults with relapsed/refractory lymphoblastic leukemia/lymphoma
Hucks, G.E, Barrett, D, Rheingold, S.R, Aplenc, R, Teachey, D.T, Callahan, C, Baniewicz, D, White, C, Talekar, M, Shaw, P, Brogdon, J.L, Young, R, Scholler, J, Marcucci, K, Chew, A, Levine, B.L, Frey, N, Porter, D, Lacey, S, Melenhorst, J, June, C, Grupp, S, Maude, S
Published in Cytotherapy (Oxford, England) (01.05.2017)
Published in Cytotherapy (Oxford, England) (01.05.2017)
Get full text
Journal Article
Durable Remissions with Control of Cytokine Release Syndrome (CRS) Using T Cells Expressing CD19 Targeted Chimeric Antigen Receptor (CAR) CTL019 to Treat Relapsed/Refractory (R/R) Acute Lymphoid Leukemia (ALL)
Levine, B.L, Maude, S, Zheng, Z, Shaw, P, Ambrose, D, Aplenc, R, Barker, C, Barrett, D, Brogdon, J, Callahan, C, Chen, F, Chew, A, Suhoski Davis, M.M, Fesnak, A.D, Finklestein, J, Frey, N, Lacey, S, Lamontagne, A, Lewitt, L, Loew, A, Marcucci, K, Melenhorst, J, Motley, L, Mudambi, M, Nazimuddin, F, O'Rourke, M, Porter, D, Rheingold, S.R, Scholler, J, Tayor, C, White, C, Wood, P, Young, R, Teachey, D.T, June, C, Grupp, S
Published in Cytotherapy (Oxford, England) (01.06.2016)
Published in Cytotherapy (Oxford, England) (01.06.2016)
Get full text
Journal Article
Adoptive transfer of gene-modified T-cells engineered to express high-affinity tcr's for cancer-testis antigens NY-ESO-1 or lage-1, in multiple myeloma (MM) patients post autologous hematopoietic stem cell transplant (ASCT)
Levine, B.L, Rapoport, A.P, Stadtmauer, E.A, Vogl, D.T, Weiss, B, Binder-Scholl, G.K, Smethurst, D.P, Brewer, J.E, Bennett, A.D, Gerry, A.B, Pumphrey, N.J, Tayton-Martin, H.K, Ribiero, L, Veloso, E.A, Finklestein, J, Kulikovskaya, I, Gupta, M, Suppa, E, Mikheeva, T, Zheng, Z, Brennan, A.L, Bersenev, A, Tripic, T, Cribioli, E, Cotte, J, Badros, A.Z, Yanovich, S, Akpek, G, McConville, H, Kerr, N, Philip, S, Betts, K, Westphal, S, Kalos, M, Jacobsen, B.K, June, C.H
Published in Cytotherapy (Oxford, England) (01.04.2013)
Published in Cytotherapy (Oxford, England) (01.04.2013)
Get full text
Journal Article
Regulatory Affairs, Quality Systems, Policy, and Ethics: FDA CYTOTOXICITY AND POTENCY REVIEW: OPPORTUNITIES FOR ASSAY CLARITY
Barber-Rotenberg, J.S., Leskowitz, R.M., Jadlowsky, J., Hexner, E., Binder, Z.A., Bhoj, V.G., Siegel, D., Fraietta, J.A., O’Rourke, D., Levine, B.L., Chew, A., June, C.
Published in Cytotherapy (Oxford, England) (01.05.2023)
Published in Cytotherapy (Oxford, England) (01.05.2023)
Get full text
Journal Article
Immunotherapy: MULTIPLEX GENETIC ENGINEERING USING MICRORNA (MIRNA)-MEDIATED GENE SILENCING IN MESOTHELIN-DIRECTED CAR (M5CAR) T CELLS
Golinelli, G., Scholler, J., Song, D., Gabunia, K., Fan, T., Berjis, A., Sheppard, N., Alessandrini, M., Roussel-Gervais, A., Šakić, A., Kili, S., June, C., Levine, B.L.
Published in Cytotherapy (Oxford, England) (01.05.2023)
Published in Cytotherapy (Oxford, England) (01.05.2023)
Get full text
Journal Article
1027 - Immunotherapy: MULTIPLEX GENETIC ENGINEERING USING MICRORNA (MIRNA)-MEDIATED GENE SILENCING IN MESOTHELIN-DIRECTED CAR (M5CAR) T CELLS
Golinelli, G., Scholler, J., Song, D., Gabunia, K., Fan, T., Berjis, A., Sheppard, N., Alessandrini, M., Roussel-Gervais, A., Šakić, A., Kili, S., June, C., Levine, B.L.
Published in Cytotherapy (Oxford, England) (01.05.2023)
Published in Cytotherapy (Oxford, England) (01.05.2023)
Get full text
Journal Article
14 - Regulatory Affairs, Quality Systems, Policy, and Ethics: FDA CYTOTOXICITY AND POTENCY REVIEW: OPPORTUNITIES FOR ASSAY CLARITY
Barber-Rotenberg, J.S., Leskowitz, R.M., Jadlowsky, J., Hexner, E., Binder, Z.A., Bhoj, V.G., Siegel, D., Fraietta, J.A., O’Rourke, D., Levine, B.L., Chew, A., June, C.
Published in Cytotherapy (Oxford, England) (01.05.2023)
Published in Cytotherapy (Oxford, England) (01.05.2023)
Get full text
Journal Article
Predictive Modeling Demonstrating a Two-Factor Signature As Early As a Week Prior to Harvest For Chimeric Antigen Receptor (CAR) T-Cell Manufacturing Growth
Xu, J., Pequignot, E., Holland, D., Lamontagne, A., Siegel, D., Levine, B.L., Davis, M.M.
Published in Cytotherapy (Oxford, England) (01.05.2020)
Published in Cytotherapy (Oxford, England) (01.05.2020)
Get full text
Journal Article
Discussion of the requirements, challenges and processing adaptions involved in an academic technology transfer of neo-antigen peptide pulsed dendritic cells
L. Brennan, A., Guilliams, J., Fox, E., Carreno, B., Linette, G., Levine, B.L., Plesaw, G., Siegel, D., Mackey, S., Fesnak, A.
Published in Cytotherapy (Oxford, England) (01.05.2021)
Published in Cytotherapy (Oxford, England) (01.05.2021)
Get full text
Journal Article
Process Development and Manufacturing: EVALUATION OF COMMERCIAL CRYOMEDIA FORMULATIONS FOR LEUKAPHERESIS STARTING MATERIAL AND FINAL T CELL THERAPEUTIC PRODUCTS
Russell, A.L., Pequignot, E., Xu, J., Gohil, M., Haines, K.M., Jain, A., Alvarado, F., Sporici, K., Holland, D., Karar, J., Jadlowsky, J., Plesa, G., Siegel, D., Levine, B.L., Davis, M.M.
Published in Cytotherapy (Oxford, England) (01.05.2022)
Published in Cytotherapy (Oxford, England) (01.05.2022)
Get full text
Journal Article
832 - Process Development and Manufacturing: CAR T CELL MANUFACTURING (MFG) IN A 2ML MICROBIOREACTOR
Gohil, M., Jain, A., Lee, K., Pequignot, E., Mackey, S., Trivedi, H., Sporici, K., Russell, A.L., Dai, A., Petrella, J., Hebbal, S., Gonzalez, V.E., Kulikovskaya, I., Brennan, A.L., Svoboda, J., Levine, B.L., June, C., Siegel, D., Fraietta, J.A., Plesa, G., Davis, M.M.
Published in Cytotherapy (Oxford, England) (01.05.2023)
Published in Cytotherapy (Oxford, England) (01.05.2023)
Get full text
Journal Article
Process Development and Manufacturing: CAR T CELL MANUFACTURING (MFG) IN A 2ML MICROBIOREACTOR
Gohil, M., Jain, A., Lee, K., Pequignot, E., Mackey, S., Trivedi, H., Sporici, K., Russell, A.L., Dai, A., Petrella, J., Hebbal, S., Gonzalez, V.E., Kulikovskaya, I., Brennan, A.L., Svoboda, J., Levine, B.L., June, C., Siegel, D., Fraietta, J.A., Plesa, G., Davis, M.M.
Published in Cytotherapy (Oxford, England) (01.05.2023)
Published in Cytotherapy (Oxford, England) (01.05.2023)
Get full text
Journal Article
Maintaining excellence in a high volume academic cell therapy production facility through optimization of space utilization, operations, scheduling and staffing
Lamontagne, A., Colligon, T.A., Taylor, C., Lewitt, L., Holland, D., Buchholz, K., Migliaccio, T., Brennan, A., Levine, B.L., Plesa, G., Siegel, D.
Published in Cytotherapy (Oxford, England) (01.05.2020)
Published in Cytotherapy (Oxford, England) (01.05.2020)
Get full text
Journal Article