Novel drug transporter substrates identification: An innovative approach based on metabolomic profiling, in silico ligand screening and biological validation
Nies, Anne T., König, Jörg, Leuthold, Patrick, Damme, Katja, Winter, Stefan, Haag, Mathias, Masuda, Satohiro, Kruck, Stephan, Daniel, Hannelore, Spanier, Britta, Fromm, Martin F., Bedke, Jens, Inui, Ken-ichi, Schwab, Matthias, Schaeffeler, Elke
Published in Pharmacological research (01.10.2023)
Published in Pharmacological research (01.10.2023)
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Journal Article
Nicotinamide‐N‐methyltransferase is a promising metabolic drug target for primary and metastatic clear cell renal cell carcinoma
Reustle, Anna, Menig, Lena‐Sophie, Leuthold, Patrick, Hofmann, Ute, Stühler, Viktoria, Schmees, Christian, Becker, Michael, Haag, Mathias, Klumpp, Verena, Winter, Stefan, Büttner, Florian A., Rausch, Steffen, Hennenlotter, Jörg, Fend, Falko, Scharpf, Marcus, Stenzl, Arnulf, Bedke, Jens, Schwab, Matthias, Schaeffeler, Elke
Published in Clinical and translational medicine (01.06.2022)
Published in Clinical and translational medicine (01.06.2022)
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Journal Article
Molybdenum Cofactor Catabolism Unravels the Physiological Role of the Drug Metabolizing Enzyme Thiopurine S‐Methyltransferase
Pristup, Julika, Schaeffeler, Elke, Arjune, Sita, Hofmann, Ute, Angel Santamaria‐Araujo, Jose, Leuthold, Patrick, Friedrich, Nele, Nauck, Matthias, Mayr, Simon, Haag, Mathias, Muerdter, Thomas, Marner, Franz‐Josef, Relling, Mary V., Evans, William E., Schwarz, Guenter, Schwab, Matthias
Published in Clinical pharmacology and therapeutics (01.10.2022)
Published in Clinical pharmacology and therapeutics (01.10.2022)
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Journal Article
Simultaneous Extraction of RNA and Metabolites from Single Kidney Tissue Specimens for Combined Transcriptomic and Metabolomic Profiling
Leuthold, Patrick, Schwab, Matthias, Hofmann, Ute, Winter, Stefan, Rausch, Steffen, Pollak, Michael N, Hennenlotter, Jörg, Bedke, Jens, Schaeffeler, Elke, Haag, Mathias
Published in Journal of proteome research (07.09.2018)
Published in Journal of proteome research (07.09.2018)
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Journal Article
Comprehensive Metabolomic and Lipidomic Profiling of Human Kidney Tissue: A Platform Comparison
Leuthold, Patrick, Schaeffeler, Elke, Winter, Stefan, Büttner, Florian, Hofmann, Ute, Mürdter, Thomas E, Rausch, Steffen, Sonntag, Denise, Wahrheit, Judith, Fend, Falko, Hennenlotter, Jörg, Bedke, Jens, Schwab, Matthias, Haag, Mathias
Published in Journal of proteome research (03.02.2017)
Published in Journal of proteome research (03.02.2017)
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Journal Article
Quantitative bile acid profiling by liquid chromatography quadrupole time-of-flight mass spectrometry: monitoring hepatitis B therapy by a novel Na+-taurocholate cotransporting polypeptide inhibitor
Haag, Mathias, Hofmann, Ute, Mürdter, Thomas E, Heinkele, Georg, Leuthold, Patrick, Blank, Antje, Haefeli, Walter E, Alexandrov, Alexander, Urban, Stephan, Schwab, Matthias
Published in Analytical and bioanalytical chemistry (01.09.2015)
Published in Analytical and bioanalytical chemistry (01.09.2015)
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Journal Article
Quantitative bile acid profiling by liquid chromatography quadrupole time-of-flight mass spectrometry: monitoring hepatitis B therapy by a novel Na super(+)-taurocholate cotransporting polypeptide inhibitor
Haag, Mathias, Hofmann, Ute, Muerdter, Thomas E, Heinkele, Georg, Leuthold, Patrick, Blank, Antje, Haefeli, Walter E, Alexandrov, Alexander, Urban, Stephan, Schwab, Matthias
Published in Analytical and bioanalytical chemistry (01.09.2015)
Published in Analytical and bioanalytical chemistry (01.09.2015)
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Journal Article
Quantitative bile acid profiling by liquid chromatography quadrupole time-of-flight mass spectrometry: monitoring hepatitis B therapy by a novel Na^sup +^-taurocholate cotransporting polypeptide inhibitor
Haag, Mathias, Hofmann, Ute, Mürdter, Thomas E, Heinkele, Georg, Leuthold, Patrick, Blank, Antje, Haefeli, Walter E, Alexandrov, Alexander, Urban, Stephan, Schwab, Matthias
Published in Analytical and bioanalytical chemistry (01.09.2015)
Published in Analytical and bioanalytical chemistry (01.09.2015)
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Journal Article
Quantitative bile acid profiling by liquid chromatography quadrupole time-of-flight mass spectrometry: monitoring hepatitis B therapy by a novel Na.sup.+-taurocholate cotransporting polypeptide inhibitor
Haag, Mathias, Hofmann, Ute, Mürdter, Thomas E, Heinkele, Georg, Leuthold, Patrick, Blank, Antje, Haefeli, Walter E, Alexandrov, Alexander, Urban, Stephan, Schwab, Matthias
Published in Analytical and bioanalytical chemistry (01.09.2015)
Published in Analytical and bioanalytical chemistry (01.09.2015)
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