Targeted Delivery of a Sialic Acid-Blocking Glycomimetic to Cancer Cells Inhibits Metastatic Spread
Büll, Christian, Boltje, Thomas Jan, van Dinther, Eric A. W, Peters, Timo, de Graaf, Annemarie M. A, Leusen, Jeanette H. W, Kreutz, Martin, Figdor, Carl G, den Brok, Martijn H, Adema, Gosse J
Published in ACS nano (27.01.2015)
Published in ACS nano (27.01.2015)
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Combining Cellular Immunization and Phage Display Screening Results in Novel, FcγRI-Specific Antibodies
Krohn, Steffen, Holtrop, Tosca, Brandsma, Arianne M, Moerer, Petra, Nederend, Maaike, Darzentas, Nikos, Brüggemann, Monika, Klausz, Katja, Leusen, Jeanette H W, Peipp, Matthias
Published in Viruses (01.04.2024)
Published in Viruses (01.04.2024)
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Disruption of the sialic acid/Siglec-9 axis improves antibody-mediated neutrophil cytotoxicity towards tumor cells
Lustig, Marta, Chan, Chilam, Jansen, J H Marco, Bräutigam, Maria, Kölling, Max A, Gehlert, Carina Lynn, Baumann, Niklas, Mester, Simone, Foss, Stian, Andersen, Jan Terje, Bastian, Lorenz, Sondermann, Peter, Peipp, Matthias, Burger, Renate, Leusen, Jeanette H W, Valerius, Thomas
Published in Frontiers in immunology (2023)
Published in Frontiers in immunology (2023)
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Fc receptor inside-out signaling and possible impact on antibody therapy
Brandsma, Arianne M., Jacobino, Shamir R., Meyer, Saskia, ten Broeke, Toine, Leusen, Jeanette H. W.
Published in Immunological reviews (01.11.2015)
Published in Immunological reviews (01.11.2015)
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DC subset-specific induction of T cell responses upon antigen uptake via Fcγ receptors in vivo
Lehmann, Christian H K, Baranska, Anna, Heidkamp, Gordon F, Heger, Lukas, Neubert, Kirsten, Lühr, Jennifer J, Hoffmann, Alana, Reimer, Katharina C, Brückner, Christin, Beck, Simone, Seeling, Michaela, Kießling, Melissa, Soulat, Didier, Krug, Anne B, Ravetch, Jeffrey V, Leusen, Jeanette H W, Nimmerjahn, Falk, Dudziak, Diana
Published in The Journal of experimental medicine (01.05.2017)
Published in The Journal of experimental medicine (01.05.2017)
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Contribution of classic and alternative effector pathways in peanut-induced anaphylactic responses
Smit, Joost J, Willemsen, Karina, Hassing, Ine, Fiechter, Danielle, Storm, Gert, van Bloois, Louis, Leusen, Jeanette H W, Pennings, Maarten, Zaiss, Dietmar, Pieters, Raymond H H
Published in PloS one (14.12.2011)
Published in PloS one (14.12.2011)
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Specificity and Effector Functions of Human RSV-Specific IgG from Bovine Milk
den Hartog, Gerco, Jacobino, Shamir, Bont, Louis, Cox, Linda, Ulfman, Laurien H, Leusen, Jeanette H W, van Neerven, R J Joost
Published in PloS one (06.11.2014)
Published in PloS one (06.11.2014)
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Effective, Long-Term, Neutrophil Depletion Using a Murinized Anti-Ly-6G 1A8 Antibody
Olofsen, Patricia A, Stip, Marjolein C, Jansen, J H Marco, Chan, Chilam, Nederend, Maaike, Tieland, Ralph G, Tsioumpekou, Maria, Leusen, Jeanette H W
Published in Cells (Basel, Switzerland) (27.10.2022)
Published in Cells (Basel, Switzerland) (27.10.2022)
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Recombinant dimeric IgA antibodies against the epidermal growth factor receptor mediate effective tumor cell killing
Lohse, Stefan, Derer, Stefanie, Beyer, Thomas, Klausz, Katja, Peipp, Matthias, Leusen, Jeanette H W, van de Winkel, Jan G J, Dechant, Michael, Valerius, Thomas
Published in The Journal of immunology (1950) (15.03.2011)
Published in The Journal of immunology (1950) (15.03.2011)
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Glutaminyl cyclase is an enzymatic modifier of the CD47- SIRPα axis and a target for cancer immunotherapy
Logtenberg, Meike E. W., Jansen, J. H. Marco, Raaben, Matthijs, Toebes, Mireille, Franke, Katka, Brandsma, Arianne M., Matlung, Hanke L., Fauster, Astrid, Gomez-Eerland, Raquel, Bakker, Noor A. M., van der Schot, Simone, Marijt, Koen A., Verdoes, Martijn, Haanen, John B. A. G., van den Berg, Joost H., Neefjes, Jacques, van den Berg, Timo K., Brummelkamp, Thijn R., Leusen, Jeanette H. W., Scheeren, Ferenc A., Schumacher, Ton N.
Published in Nature medicine (01.04.2019)
Published in Nature medicine (01.04.2019)
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Recombinant Soluble Respiratory Syncytial Virus F Protein That Lacks Heptad Repeat B, Contains a GCN4 Trimerization Motif and Is Not Cleaved Displays Prefusion-Like Characteristics
Widjaja, Ivy, Rigter, Alan, Jacobino, Shamir, van Kuppeveld, Frank J M, Leenhouts, Kees, Palomo, Concepción, Melero, Jose A, Leusen, Jeanette H W, Haijema, Bert Jan, Rottier, Peter J M, de Haan, Cornelis A M
Published in PloS one (24.06.2015)
Published in PloS one (24.06.2015)
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The Therapeutic CD38 Monoclonal Antibody Daratumumab Induces Programmed Cell Death via Fcγ Receptor-Mediated Cross-Linking
Overdijk, Marije B, Jansen, J H Marco, Nederend, Maaike, Lammerts van Bueren, Jeroen J, Groen, Richard W J, Parren, Paul W H I, Leusen, Jeanette H W, Boross, Peter
Published in The Journal of immunology (1950) (01.08.2016)
Published in The Journal of immunology (1950) (01.08.2016)
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Potent Fc Receptor Signaling by IgA Leads to Superior Killing of Cancer Cells by Neutrophils Compared to IgG
Brandsma, Arianne M, Bondza, Sina, Evers, Mitchell, Koutstaal, Rosanne, Nederend, Maaike, Jansen, J H Marco, Rösner, Thies, Valerius, Thomas, Leusen, Jeanette H W, Ten Broeke, Toine
Published in Frontiers in immunology (11.04.2019)
Published in Frontiers in immunology (11.04.2019)
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Cytokine-induced immune complex binding to the high-affinity IgG receptor, FcγRI, in the presence of monomeric IgG
van der Poel, Cees E., Karssemeijer, Roos A., Boross, Peter, van der Linden, Joke A., Blokland, Miranda, van de Winkel, Jan G.J., Leusen, Jeanette H.W.
Published in Blood (09.12.2010)
Published in Blood (09.12.2010)
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The relevance of tumor target expression levels on IgA-mediated cytotoxicity in cancer immunotherapy
Chan, Chilam, Cabanes, Núria Casalé, Jansen, J. H. Marco, Guillaume, Joël, Nederend, Maaike, Passchier, Elsemieke M., Gómez-Mellado, Valentina E., Peipp, Matthias, Boes, Marianne, van Tetering, Geert, Leusen, Jeanette H. W.
Published in Cancer Immunology, Immunotherapy : CII (03.10.2024)
Published in Cancer Immunology, Immunotherapy : CII (03.10.2024)
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Targeting Myeloid Checkpoint Molecules in Combination With Antibody Therapy: A Novel Anti-Cancer Strategy With IgA Antibodies?
Chan, Chilam, Lustig, Marta, Baumann, Niklas, Valerius, Thomas, van Tetering, Geert, Leusen, Jeanette H. W.
Published in Frontiers in immunology (05.07.2022)
Published in Frontiers in immunology (05.07.2022)
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