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Pre-clinical development of a novel CD3-CD123 bispecific T-cell engager using cross-over dual-variable domain (CODV) format for acute myeloid leukemia (AML) treatment
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돌연변이 Fab 도메인을 포함하는 다중특이성 결합 단백질
JUNG JENNIFER, RAO ERCOLE, AMARAL MARTA, LEUSCHNER WULF DIRK, BEIL CHRISTIAN, TIWARI GARIMA, FOCKEN INGO, HOELPER SORAYA, WEIL SANDRA, HESSLER GERHARD, LANGE CHRISTIAN
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YANG ZHI YONG, SEUNG EDWARD, CORVEY CARSTEN, NABEL GARY J, WEI RONNIE, RAO ERCOLE, LEUSCHNER WULF DIRK, BEIL CHRISTIAN, LANGE CHRISTIAN, WU LAN, BENINGA JOCHEN
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Trispecific broadly neutralizing HIV antibodies mediate potent SHIV protection in macaques
Xu, Ling, Pegu, Amarendra, Rao, Ercole, Doria-Rose, Nicole, Beninga, Jochen, McKee, Krisha, Lord, Dana M., Wei, Ronnie R., Deng, Gejing, Louder, Mark, Schmidt, Stephen D., Mankoff, Zachary, Wu, Lan, Asokan, Mangaiarkarasi, Beil, Christian, Lange, Christian, Leuschner, Wulf Dirk, Kruip, Jochen, Sendak, Rebecca, Kwon, Young Do, Zhou, Tongqing, Chen, Xuejun, Bailer, Robert T., Wang, Keyun, Choe, Misook, Tartaglia, Lawrence J., Barouch, Dan H., O’Dell, Sijy, Todd, John-Paul, Burton, Dennis R., Roederer, Mario, Connors, Mark, Koup, Richard A., Kwong, Peter D., Yang, Zhi-yong, Mascola, John R., Nabel, Gary J.
Published in Science (American Association for the Advancement of Science) (06.10.2017)
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항-CD3 항체, 항-CD123 항체, 및 CD3 및/또는 CD123에 특이적으로 결합하는 이중특이적 항체
CARREZ CHANTAL, LEMOINE CENDRINE, GUERIF STEPHANE, LEUSCHNER WULF DIRK, BENINGA JOCHEN, KROLL KATJA, SCHNEIDER MARION, RAO ERCOLE, BARRIERE CEDRIC, ALBRECHT JANA, BEIL CHRISTIAN, LANGE CHRISTIAN, WETZEL MARIE CECILE, WONEROW PETER
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Year of Publication 05.09.2017
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A multivalent antibody assembled from different building blocks using tag/catcher systems: a case study
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Published in Protein engineering, design and selection (17.02.2022)
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HIV 감염의 예방 또는 치료를 위한 3특이성 및/또는 3가 결합 단백질
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Year of Publication 11.06.2018
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Year of Publication 11.06.2018
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Abstract 1785: Pre-clinical development of a novel CD3-CD123 bispecific T-cell engager using Cross-Over-Dual-Variable-Domain (CODV) format for the treatment of acute myeloid leukemia (AML)
Bonnevaux, Helene, Guerif, Stephane, Albrecht, Jana, Jouannot, Erwan, Bassinet, Laurent, Vergezac, Agnès, Beil, Christian, Lange, Christian, Leuschner, Wulf Dirk, Caron, Anne, Amara, Celine, Barriere, Cedric, Siavellis, Justine, Bardet, Valerie, Luna, Ernesto, Drake, Donald, Rao, Ercole, Oprea, Corina, Wonerow, Peter, Carrez, Chantal, Blanc, Veronique, Hsu, Karl, Wiederschain, Dmitri, Fraenkel, Paula G.
Published in Cancer research (Chicago, Ill.) (01.07.2018)
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Year of Publication 05.07.2024
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MULTISPECIFIC ANTIBODIES FACILITATING SELECTIVE LIGHT CHAIN PAIRING
LEUSCHNER, Wulf-Dirk, LANGE, Christian, BEIL, Christian, RAO, Ercole, LANGER, Thomas, FOCKEN, Ingo, KROLL, Katja, SPINDLER, Nadja
Year of Publication 28.06.2024
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Year of Publication 28.06.2024
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MULTISPECIFIC ANTIBODIES FACILITATING SELECTIVE LIGHT CHAIN PAIRING
LEUSCHNER, WULF-DIRK, RAO, ERCOLE, SPINDLER, NADJA, LANGER, THOMAS, LANGE, CHRISTIAN, BEIL, CHRISTIAN, KROLL, KATJA, FOCKEN, INGO
Year of Publication 24.06.2024
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Year of Publication 24.06.2024
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MULTISPECIFIC ANTIBODIES FACILITATING SELECTIVE LIGHT CHAIN PAIRING
LEUSCHNER, WULF-DIRK, RAO, ERCOLE, SPINDLER, NADJA, LANGER, THOMAS, LANGE, CHRISTIAN, BEIL, CHRISTIAN, KROLL, KATJA, FOCKEN, INGO
Year of Publication 31.05.2024
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Year of Publication 31.05.2024
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