Long-Term GABA Administration Induces Alpha Cell-Mediated Beta-like Cell Neogenesis
Ben-Othman, Nouha, Vieira, Andhira, Courtney, Monica, Record, Fabien, Gjernes, Elisabet, Avolio, Fabio, Hadzic, Biljana, Druelle, Noémie, Napolitano, Tiziana, Navarro-Sanz, Sergi, Silvano, Serena, Al-Hasani, Keith, Pfeifer, Anja, Lacas-Gervais, Sandra, Leuckx, Gunter, Marroquí, Laura, Thévenet, Julien, Madsen, Ole Dragsbaek, Eizirik, Decio Laks, Heimberg, Harry, Kerr-Conte, Julie, Pattou, François, Mansouri, Ahmed, Collombat, Patrick
Published in Cell (12.01.2017)
Published in Cell (12.01.2017)
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The inactivation of Arx in pancreatic α-cells triggers their neogenesis and conversion into functional β-like cells
Courtney, Monica, Gjernes, Elisabet, Druelle, Noémie, Ravaud, Christophe, Vieira, Andhira, Ben-Othman, Nouha, Pfeifer, Anja, Avolio, Fabio, Leuckx, Gunter, Lacas-Gervais, Sandra, Burel-Vandenbos, Fanny, Ambrosetti, Damien, Hecksher-Sorensen, Jacob, Ravassard, Philippe, Heimberg, Harry, Mansouri, Ahmed, Collombat, Patrick
Published in PLoS genetics (01.10.2013)
Published in PLoS genetics (01.10.2013)
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Transient cytokine treatment induces acinar cell reprogramming and regenerates functional beta cell mass in diabetic mice
Baeyens, Luc, Lemper, Marie, Leuckx, Gunter, De Groef, Sofie, Bonfanti, Paola, Stangé, Geert, Shemer, Ruth, Nord, Christoffer, Scheel, David W, Pan, Fong C, Ahlgren, Ulf, Gu, Guoqiang, Stoffers, Doris A, Dor, Yuval, Ferrer, Jorge, Gradwohl, Gerard, Wright, Christopher V E, Van de Casteele, Mark, German, Michael S, Bouwens, Luc, Heimberg, Harry
Published in Nature biotechnology (01.01.2014)
Published in Nature biotechnology (01.01.2014)
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Semi-automated digital measurement as the method of choice for beta cell mass analysis
Coppens, Violette, Leuckx, Gunter, Heremans, Yves, Staels, Willem, Verdonck, Yannick, Baeyens, Luc, De Leu, Nico, Heimberg, Harry
Published in PloS one (06.02.2018)
Published in PloS one (06.02.2018)
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Macrophage dynamics are regulated by local macrophage proliferation and monocyte recruitment in injured pancreas
Gassen, Naomi, Overmeire, Eva, Leuckx, Gunter, Heremans, Yves, Groef, Sofie, Cai, Ying, Elkrim, Yvon, Gysemans, Conny, Stijlemans, Benoît, Casteele, Mark, Baetselier, Patrick, Leu, Nico, Heimberg, Harry, Ginderachter, Jo A.
Published in European journal of immunology (01.05.2015)
Published in European journal of immunology (01.05.2015)
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Retraction Note: Transient cytokine treatment induces acinar cell reprogramming and regenerates functional beta cell mass in diabetic mice
Baeyens, Luc, Lemper, Marie, Leuckx, Gunter, De Groef, Sofie, Bonfanti, Paola, Stangé, Geert, Shemer, Ruth, Nord, Christoffer, Scheel, David W., Pan, Fong C., Ahlgren, Ulf, Gu, Guoqiang, Stoffers, Doris A., Dor, Yuval, Ferrer, Jorge, Gradwohl, Gerard, Wright, Christopher V. E., Van de Casteele, Mark, German, Michael S., Bouwens, Luc, Heimberg, Harry
Published in Nature biotechnology (01.03.2020)
Published in Nature biotechnology (01.03.2020)
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Concise Review: Macrophages: Versatile Gatekeepers During Pancreatic β‐Cell Development, Injury, and Regeneration
Van Gassen, Naomi, Staels, Willem, Van Overmeire, Eva, De Groef, Sofie, Sojoodi, Mozhdeh, Heremans, Yves, Leuckx, Gunter, Van de Casteele, Mark, Van Ginderachter, Jo A., Heimberg, Harry, De Leu, Nico
Published in Stem cells translational medicine (01.06.2015)
Published in Stem cells translational medicine (01.06.2015)
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Adult Duct-Lining Cells Can Reprogram into β-like Cells Able to Counter Repeated Cycles of Toxin-Induced Diabetes
Al-Hasani, Keith, Pfeifer, Anja, Courtney, Monica, Ben-Othman, Nouha, Gjernes, Elisabet, Vieira, Andhira, Druelle, Noémie, Avolio, Fabio, Ravassard, Philippe, Leuckx, Gunter, Lacas-Gervais, Sandra, Ambrosetti, Damien, Benizri, Emmanuel, Hecksher-Sorensen, Jacob, Gounon, Pierre, Ferrer, Jorge, Gradwohl, Gerard, Heimberg, Harry, Mansouri, Ahmed, Collombat, Patrick
Published in Developmental cell (15.07.2013)
Published in Developmental cell (15.07.2013)
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Vegf-A mRNA transfection as a novel approach to improve mouse and human islet graft revascularisation
Staels, Willem, Verdonck, Yannick, Heremans, Yves, Leuckx, Gunter, De Groef, Sofie, Heirman, Carlo, de Koning, Eelco, Gysemans, Conny, Thielemans, Kris, Baeyens, Luc, Heimberg, Harry, De Leu, Nico
Published in Diabetologia (01.08.2018)
Published in Diabetologia (01.08.2018)
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Evidence of Tissue Repair in Human Donor Pancreas After Prolonged Duration of Stay in Intensive Care
Smeets, Silke, Stangé, Geert, Leuckx, Gunter, Roelants, Lisbeth, Cools, Wilfried, De Paep, Diedert Luc, Ling, Zhidong, De Leu, Nico, In't Veld, Peter
Published in Diabetes (New York, N.Y.) (01.03.2020)
Published in Diabetes (New York, N.Y.) (01.03.2020)
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Inhibition of Cdk5 Promotes β-Cell Differentiation From Ductal Progenitors
Liu, Ka-Cheuk, Leuckx, Gunter, Sakano, Daisuke, Seymour, Philip A, Mattsson, Charlotte L, Rautio, Linn, Staels, Willem, Verdonck, Yannick, Serup, Palle, Kume, Shoen, Heimberg, Harry, Andersson, Olov
Published in Diabetes (New York, N.Y.) (01.01.2018)
Published in Diabetes (New York, N.Y.) (01.01.2018)
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Journal Article
Estrogen Receptor α Regulates β-Cell Formation During Pancreas Development and Following Injury
Yuchi, Yixing, Cai, Ying, Legein, Bart, De Groef, Sofie, Leuckx, Gunter, Coppens, Violette, Van Overmeire, Eva, Staels, Willem, De Leu, Nico, Martens, Geert, Van Ginderachter, Jo A, Heimberg, Harry, Van de Casteele, Mark
Published in Diabetes (New York, N.Y.) (01.09.2015)
Published in Diabetes (New York, N.Y.) (01.09.2015)
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Discovery and 3D imaging of a novel ΔNp63-expressing basal cell type in human pancreatic ducts with implications in disease
Martens, Sandrina, Coolens, Katarina, Van Bulck, Mathias, Arsenijevic, Tatjana, Casamitjana, Joan, Fernandez Ruiz, Angel, El Kaoutari, Abdessamad, Martinez de Villareal, Jaime, Madhloum, Hediel, Esni, Farzad, Heremans, Yves, Leuckx, Gunter, Heimberg, Harry, Bouwens, Luc, Jacquemin, Patrick, De Paep, Diedert Luc, in't Veld, Peter, D'Haene, Nicky, Bouchart, Christelle, Dusetti, Nelson, Van Laethem, Jean-Luc, Waelput, Wim, Lefesvre, Pierre, Real, Francisco X, Rovira, Meritxell, Rooman, Ilse
Published in Gut (30.07.2021)
Published in Gut (30.07.2021)
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Conditional islet hypovascularisation does not preclude beta cell expansion during pregnancy in mice
Staels, Willem, Heremans, Yves, Leuckx, Gunter, Van Gassen, Naomi, Salinno, Ciro, De Groef, Sofie, Cools, Martine, Keshet, Eli, Dor, Yuval, Heimberg, Harry, De Leu, Nico
Published in Diabetologia (01.06.2017)
Published in Diabetologia (01.06.2017)
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Human multipotent adult progenitor cells enhance islet function and revascularisation when co-transplanted as a composite pellet in a mouse model of diabetes
Cunha, João Paulo M. C. M., Leuckx, Gunter, Sterkendries, Peter, Korf, Hannelie, Bomfim-Ferreira, Gabriela, Overbergh, Lutgart, Vaes, Bart, Heimberg, Harry, Gysemans, Conny, Mathieu, Chantal
Published in Diabetologia (01.01.2017)
Published in Diabetologia (01.01.2017)
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The zinc finger transcription factor PW1/PEG3 restrains murine beta cell cycling
Sojoodi, Mozhdeh, Stradiot, Leslie, Tanaka, Karo, Heremans, Yves, Leuckx, Gunter, Besson, Vanessa, Staels, Willem, Van de Casteele, Mark, Marazzi, Giovanna, Sassoon, David, Heimberg, Harry, Bonfanti, Paola
Published in Diabetologia (01.07.2016)
Published in Diabetologia (01.07.2016)
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Mouse beta cell proliferation is inhibited by thymidine analogue labelling
Van de Casteele, Mark, Cai, Ying, Leuckx, Gunter, Heimberg, Harry
Published in Diabetologia (01.12.2013)
Published in Diabetologia (01.12.2013)
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Journal Article
Partial Duct Ligation: β-Cell Proliferation and Beyond
VAN DE CASTEELE, Mark, LEUCKX, Gunter, HEIMBERG, Harry, YING CAI, YIXING YUCHI, COPPENS, Violette, DE GROEF, Sofie, VAN GASSEN, Naomi, BAEYENS, Luc, HEREMANS, Yves, WRIGHT, Christopher V. E
Published in Diabetes (New York, N.Y.) (01.08.2014)
Published in Diabetes (New York, N.Y.) (01.08.2014)
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IL-6-dependent proliferation of alpha cells in mice with partial pancreatic-duct ligation
Cai, Ying, Yuchi, Yixing, De Groef, Sofie, Coppens, Violette, Leuckx, Gunter, Baeyens, Luc, Van de Casteele, Mark, Heimberg, Harry
Published in Diabetologia (01.07.2014)
Published in Diabetologia (01.07.2014)
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Journal Article
Sources of beta cells inside the pancreas
De Groef, Sofie, Staels, Willem, Van Gassen, Naomi, Lemper, Marie, Yuchi, Yixing, Sojoodi, Mozhdeh, Bussche, Leen, Heremans, Yves, Leuckx, Gunter, De Leu, Nico, Van de Casteele, Mark, Baeyens, Luc, Heimberg, Harry
Published in Diabetologia (01.09.2016)
Published in Diabetologia (01.09.2016)
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Book Review