Pharmacokinetics and pharmacodynamics across infusion rates of intravenously administered nipocalimab: results of a phase 1, placebo-controlled study
Leu, Jocelyn H, Vermeulen, An, Abbes, Claudia, Arroyo, Santiago, Denney, William S, Ling, Leona E
Published in Frontiers in neuroscience (01.02.2024)
Published in Frontiers in neuroscience (01.02.2024)
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Pooled safety results across phase 3 randomized trials of intravenous golimumab in rheumatoid arthritis, psoriatic arthritis, and ankylosing spondylitis
Husni, M Elaine, Deodhar, Atul, Schwartzman, Sergio, Chakravarty, Soumya D, Hsia, Elizabeth C, Leu, Jocelyn H, Zhou, Yiying, Lo, Kim H, Kavanaugh, Arthur
Published in Arthritis research & therapy (21.03.2022)
Published in Arthritis research & therapy (21.03.2022)
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Nipocalimab, an anti-FcRn monoclonal antibody, in participants with moderate to severe active rheumatoid arthritis and inadequate response or intolerance to anti-TNF therapy: results from the phase 2a IRIS-RA study
Taylor, Peter C, Schett, Georg, Huizinga, Tom WJ, Wang, Qingmin, Ibrahim, Fowzia, Zhou, Bei, Liva, Sophia G, Shaik, Jafar Sadik B, Xiong, Yuan, Leu, Jocelyn H, Panchakshari, Rohit A, Loza, Matthew J, Ma, Keying, Dhatt, Harman, Rojo Cella, Ricardo, Karyekar, Chetan S, Cuff, Carolyn A, Gao, Sheng, Fei, Kaiyin
Published in Rheumatic & musculoskeletal diseases open (28.06.2024)
Published in Rheumatic & musculoskeletal diseases open (28.06.2024)
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Golimumab and Beta-Cell Function in Youth with New-Onset Type 1 Diabetes
Quattrin, Teresa, Haller, Michael J, Steck, Andrea K, Felner, Eric I, Li, Yinglei, Xia, Yichuan, Leu, Jocelyn H, Zoka, Ramineh, Hedrick, Joseph A, Rigby, Mark R, Vercruysse, Frank
Published in The New England journal of medicine (19.11.2020)
Published in The New England journal of medicine (19.11.2020)
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Safety and Efficacy of Intravenous Golimumab in Patients With Active Psoriatic Arthritis: Results Through Week Twenty-Four of the GO-VIBRANT Study
Kavanaugh, Arthur, Husni, M Elaine, Harrison, Diane D, Kim, Lilianne, Lo, Kim Hung, Leu, Jocelyn H, Hsia, Elizabeth C
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.11.2017)
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.11.2017)
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Population Pharmacokinetics and Exposure-Response Modeling Analyses of Golimumab in Children and Young Adults With Recently Diagnosed Type 1 Diabetes
Lee, Jong Bong, Zhou, Wangda, Xu, Zhenhua, Hedrick, Joseph A, Leu, Jocelyn H
Published in Journal of clinical pharmacology (01.06.2023)
Published in Journal of clinical pharmacology (01.06.2023)
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Effect of the rate of niacin administration on the plasma and urine pharmacokinetics of niacin and its metabolites
Menon, Rajeev M, González, Mario A, Adams, Marijke H, Tolbert, Dwain S, Leu, Jocelyn H, Cefali, Eugenio A
Published in Journal of clinical pharmacology (01.06.2007)
Published in Journal of clinical pharmacology (01.06.2007)
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Development of Therapeutic Proteins for a New Subcutaneous Route of Administration After the Establishment of Intravenous Dosages: A Systematic Review
Xu, Zhenhua, Leu, Jocelyn H, Xu, Yan, Nnane, Ivo, Liva, Sophia G, Wang-Lin, Shun Xin, Kudgus-Lokken, Rachel, Vermeulen, An, Ouellet, Daniele
Published in Clinical pharmacology and therapeutics (01.05.2023)
Published in Clinical pharmacology and therapeutics (01.05.2023)
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Clinical efficacy, radiographic and safety findings through 5 years of subcutaneous golimumab treatment in patients with active psoriatic arthritis: results from a long-term extension of a randomised, placebo-controlled trial (the GO-REVEAL study)
Kavanaugh, Arthur, McInnes, Iain B, Mease, Philip, Krueger, Gerald G, Gladman, Dafna, van der Heijde, Désirée, Zhou, Yiying, Lu, Jiandong, Leu, Jocelyn H, Goldstein, Neil, Beutler, Anna
Published in Annals of the rheumatic diseases (01.09.2014)
Published in Annals of the rheumatic diseases (01.09.2014)
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Safety and Efficacy of Golimumab Administered Intravenously in Adults with Ankylosing Spondylitis: Results through Week 28 of the GO-ALIVE Study
Deodhar, Atul, Reveille, John D, Harrison, Diane D, Kim, Lilianne, Lo, Kim Hung, Leu, Jocelyn H, Hsia, Elizabeth C
Published in Journal of rheumatology (01.03.2018)
Published in Journal of rheumatology (01.03.2018)
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Immunogenicity of golimumab and its clinical relevance in patients with rheumatoid arthritis, psoriatic arthritis and ankylosing spondylitis
Leu, Jocelyn H, Adedokun, Omoniyi J, Gargano, Cynthia, Hsia, Elizabeth C, Xu, Zhenhua, Shankar, Gopi
Published in Rheumatology (Oxford, England) (01.03.2019)
Published in Rheumatology (Oxford, England) (01.03.2019)
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Subcutaneous golimumab for children with active polyarticular-course juvenile idiopathic arthritis: results of a multicentre, double-blind, randomised-withdrawal trial
Brunner, Hermine I, Ruperto, Nicolino, Tzaribachev, Nikolay, Horneff, Gerd, Chasnyk, Vyacheslav G, Panaviene, Violeta, Abud-Mendoza, Carlos, Reiff, Andreas, Alexeeva, Ekaterina, Rubio-Pérez, Nadina, Keltsev, Vladimir, Kingsbury, Daniel J, del Rocio Maldonado Velázquez, Maria, Nikishina, Irina, Silverman, Earl D, Joos, Rik, Smolewska, Elzbieta, Bandeira, Márcia, Minden, Kirsten, van Royen-Kerkhof, Annet, Emminger, Wolfgang, Foeldvari, Ivan, Lauwerys, Bernard R, Sztajnbok, Flavio, Gilmer, Keith E, Xu, Zhenhua, Leu, Jocelyn H, Kim, Lilianne, Lamberth, Sarah L, Loza, Matthew J, Lovell, Daniel J, Martini, Alberto
Published in Annals of the rheumatic diseases (01.01.2018)
Published in Annals of the rheumatic diseases (01.01.2018)
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Journal Article
Safety and Efficacy of Intravenous Golimumab in Adults with Ankylosing Spondylitis: Results through 1 Year of the GO-ALIVE Study
Reveille, John D, Deodhar, Atul, Caldron, Paul H, Dudek, Anna, Harrison, Diane D, Kim, Lilianne, Lo, Kim Hung, Leu, Jocelyn H, Hsia, Elizabeth C
Published in Journal of rheumatology (01.10.2019)
Published in Journal of rheumatology (01.10.2019)
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Journal Article
Efficacy and Safety of Intravenous Golimumab Through One Year in Patients With Active Psoriatic Arthritis
Husni, M. Elaine, Kavanaugh, Arthur, Murphy, Frederick, Rekalov, Dmytro, Harrison, Diane D., Kim, Lilianne, Lo, Kim Hung, Leu, Jocelyn H., Hsia, Elizabeth C.
Published in Arthritis care & research (2010) (01.06.2020)
Published in Arthritis care & research (2010) (01.06.2020)
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Journal Article
Population Pharmacokinetic and Exposure–Response Model Simulations: Predicted Exposure and Efficacy for Maintenance Doses of Intravenous Golimumab Every 6 or 8 Weeks in Patients With Moderately to Severely Active Rheumatoid Arthritis
Lee, Jong Bong, Broadwell, Aaron, Fan, Yijun, Hu, Chuanpu, Adedokun, Omoniyi J., Chakravarty, Soumya D., Zhou, Honghui, Xu, Zhenhua, Leu, Jocelyn H.
Published in Clinical therapeutics (01.03.2022)
Published in Clinical therapeutics (01.03.2022)
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Pharmacokinetics and Pharmacodynamics of Nipocalimab, a Neonatal Fc Receptor Blocker, in Healthy Japanese Volunteers
Matsushima, Nobuko, Shibata, Sayori, Leu, Jocelyn H., Vermeulen, An, Duffner, Jay, Ling, Leona E., Schwartz, Lisa B., Harigae, Hideo
Published in Clinical drug investigation (01.08.2024)
Published in Clinical drug investigation (01.08.2024)
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Journal Article
Immunogenicity of Golimumab and its Clinical Relevance in Patients With Ulcerative Colitis
Adedokun, Omoniyi J, Gunn, George R, Leu, Jocelyn H, Gargano, Cynthia, Xu, Zhenhua, Sandborn, William J, Rutgeerts, Paul, Shankar, Gopi
Published in Inflammatory bowel diseases (01.09.2019)
Published in Inflammatory bowel diseases (01.09.2019)
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Journal Article
Intravenous Golimumab in Children With Polyarticular-Course Juvenile Idiopathic Arthritis: Long-Term Extension of an Open-Label Phase III Study
Brunner, Hermine I, Pacheco-Tena, César, Louw, Ingrid, Vega-Cornejo, Gabriel, Alexeeva, Ekaterina, Appenzeller, Simone, Chasnyk, Vyacheslav, Griffin, Thomas, Suarez, Carmen Navarrete, Knupp-Oliveira, Sheila, Zeft, Andrew, Aviel, Yonatan Butbul, De Ranieri, Deirdre, Gottlieb, Beth S, Levy, Deborah M, Rabinovich, C Egla, Silva, Clóvis Artur, Spivakovsky, Yury, Uziel, Yosef, Ringold, Sarah, Xu, Xie L, Leu, Jocelyn H, Lam, Edwin, Wang, Yuhua, Lovell, Daniel J, Martini, Alberto, Ruperto, Nicolino
Published in Journal of rheumatology (01.11.2024)
Published in Journal of rheumatology (01.11.2024)
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Therapeutic Development in Polyarticular Course Juvenile Idiopathic Arthritis: Extrapolation, Dose Selection, and Clinical Trial Design
Schanberg, Laura E, Mulugeta, Lily Yeruk, Akinlade, Bolanle, Brunner, Hermine I, Chen, Jianmeng, Colbert, Robert A, Delgaizo, Vincent, Gastonguay, Marc R, Glaser, Rachel, Imundo, Lisa, Lovell, Daniel J, Leu, Jocelyn H, Mostafa, Nael M, Nelson, Robert M, Nigrovic, Peter A, Nikolov, Nikolay P, Rider, Lisa G, Rothwell, Rebecca, Sahajwalla, Chandrahas, Singh, Renu, Sinha, Vikram, Yancey, Carolyn L, Yao, Lynne
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.10.2023)
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.10.2023)
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Intravenous Golimumab in Patients with Polyarticular Juvenile Idiopathic Arthritis and Juvenile Psoriatic Arthritis and Subcutaneous Ustekinumab in Patients with Juvenile Psoriatic Arthritis: Extrapolation of Data from Studies in Adults and Adjacent Pediatric Populations
Leu, Jocelyn H., Shiff, Natalie J., Clark, Michael, Bensley, Karen, Lomax, Kathleen G., Berezny, Katherine, Nelson, Robert M., Zhou, Honghui, Xu, Zhenhua
Published in Paediatric drugs (01.11.2022)
Published in Paediatric drugs (01.11.2022)
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