Safety and pharmacokinetics of anti‐TFPI antibody (concizumab) in healthy volunteers and patients with hemophilia: a randomized first human dose trial
Chowdary, P., Lethagen, S., Friedrich, U., Brand, B., Hay, C., Abdul Karim, F., Klamroth, R., Knoebl, P., Laffan, M., Mahlangu, J., Miesbach, W., Dalsgaard Nielsen, J., Martín‐Salces, M., Angchaisuksiri, P.
Published in Journal of thrombosis and haemostasis (01.05.2015)
Published in Journal of thrombosis and haemostasis (01.05.2015)
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A quantitative analysis of bleeding symptoms in type 1 von Willebrand disease: results from a multicenter European study (MCMDM‐1 VWD)
TOSETTO, A., RODEGHIERO, F., CASTAMAN, G., GOODEVE, A., FEDERICI, A. B., BATLLE, J., MEYER, D., FRESSINAUD, E., MAZURIER, C., GOUDEMAND, J., EIKENBOOM, J., SCHNEPPENHEIM, R., BUDDE, U., INGERSLEV, J., VORLOVA, Z., HABART, D., HOLMBERG, L., LETHAGEN, S., PASI, J., HILL, F., PEAKE, I.
Published in Journal of thrombosis and haemostasis (01.04.2006)
Published in Journal of thrombosis and haemostasis (01.04.2006)
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Journal Article
The discriminant power of bleeding history for the diagnosis of type 1 von Willebrand disease: an international, multicenter study
RODEGHIERO, F., CASTAMAN, G., TOSETTO, A., BATLLE, J., BAUDO, F., CAPPELLETTI, A., CASANA, P., DE BOSCH, N., EIKENBOOM, J. C. J., FEDERICI, A. B., LETHAGEN, S., LINARI, S., SRIVASTAVA, A.
Published in Journal of thrombosis and haemostasis (01.12.2005)
Published in Journal of thrombosis and haemostasis (01.12.2005)
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Journal Article
Indirect comparisons of efficacy and weekly factor consumption during continuous prophylaxis with recombinant factor VIII Fc fusion protein and conventional recombinant factor VIII products
Iorio, A., Krishnan, S., Myrén, K.J., Lethagen, S., McCormick, N., Yermakov, S., Karner, P.
Published in Haemophilia : the official journal of the World Federation of Hemophilia (01.05.2017)
Published in Haemophilia : the official journal of the World Federation of Hemophilia (01.05.2017)
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European retrospective study of real‐life haemophilia treatment
Berntorp, E., Dolan, G., Hay, C., Linari, S., Santagostino, E., Tosetto, A., Castaman, G., Álvarez‐Román, MT, Parra Lopez, R., Oldenburg, J., Albert, T., Scholz, U., Holmström, M., Schved, J.‐F., Trossaërt, M., Hermans, C., Boban, A., Ludlam, C., Lethagen, S.
Published in Haemophilia : the official journal of the World Federation of Hemophilia (01.01.2017)
Published in Haemophilia : the official journal of the World Federation of Hemophilia (01.01.2017)
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von Willebrand factor-factor VIII concentrate (Haemate super( registered ) P) dosing based on pharmacokinetics: a prospective multicenter trial in elective surgery
Lethagen, S, Kyrle, P A, Castaman, G, Haertel, S, Mannucci, P M
Published in Journal of thrombosis and haemostasis (01.07.2007)
Published in Journal of thrombosis and haemostasis (01.07.2007)
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Journal Article
Detailed von Willebrand factor multimer analysis in patients with von Willebrand disease in the European study, molecular and clinical markers for the diagnosis and management of type 1 von Willebrand disease (MCMDM‐1VWD)
BUDDE, U., SCHNEPPENHEIM, R., EIKENBOOM, J., GOODEVE, A., WILL, K., DREWKE, E., CASTAMAN, G., RODEGHIERO, F., FEDERICI, A. B., BATLLE, J., PÉREZ, A., MEYER, D., MAZURIER, C., GOUDEMAND, J., INGERSLEV, J., HABART, D., VORLOVA, Z., HOLMBERG, L., LETHAGEN, S., PASI, J., HILL, F., PEAKE, I.
Published in Journal of thrombosis and haemostasis (01.05.2008)
Published in Journal of thrombosis and haemostasis (01.05.2008)
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von Willebrand factor/factor VIII concentrate (Haemate® P) dosing based on pharmacokinetics: a prospective multicenter trial in elective surgery
LETHAGEN, S., KYRLE, P. A., CASTAMAN, G., HAERTEL, S., MANNUCCI, P. M.
Published in Journal of thrombosis and haemostasis (01.07.2007)
Published in Journal of thrombosis and haemostasis (01.07.2007)
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Journal Article
Long-standing prophylactic therapy vs. episodic treatment in young people with severe haemophilia: a comparison of age-matched Danish and Russian patients
Ingerslev, J., Lethagen, S., Hvitfeldt Poulsen, L., Sørensen, B., Lopatina, E., Tentsova, I., Yastrubinetskaya, O., Plyushch, O. P.
Published in Haemophilia : the official journal of the World Federation of Hemophilia (01.01.2014)
Published in Haemophilia : the official journal of the World Federation of Hemophilia (01.01.2014)
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Journal Article
Functional characteristics of N8, a new recombinant FVIII
CHRISTIANSEN, M. L. S., BALLING, K. W., PERSSON, E., HILDEN, I., BAGGER-SØRENSEN, A., SØRENSEN, B. B., VIUFF, D., SEGEL, S., KLAUSEN, N. K., EZBAN, M., LETHAGEN, S., STEENSTRUP, T. D., KJALKE, M.
Published in Haemophilia : the official journal of the World Federation of Hemophilia (01.11.2010)
Published in Haemophilia : the official journal of the World Federation of Hemophilia (01.11.2010)
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Linkage analysis in families diagnosed with type 1 von Willebrand disease in the European study, molecular and clinical markers for the diagnosis and management of type 1 VWD
EIKENBOOM, J., VAN MARION, V., PUTTER, H., GOODEVE, A., RODEGHIERO, F., CASTAMAN, G., FEDERICI, A. B., BATLLE, J., MEYER, D., MAZURIER, C., GOUDEMAND, J., SCHNEPPENHEIM, R., BUDDE, U., INGERSLEV, J., VORLOVA, Z., HABART, D., HOLMBERG, L., LETHAGEN, S., PASI, J., HILL, F., PEAKE, I.
Published in Journal of thrombosis and haemostasis (01.04.2006)
Published in Journal of thrombosis and haemostasis (01.04.2006)
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Journal Article
Expression of 14 von Willebrand factor mutations identified in patients with type 1 von Willebrand disease from the MCMDM‐1VWD study
EIKENBOOM, J., HILBERT, L, RIBBA, A. S., HOMMAIS, A., HABART, D., MESSENGER, S., AL‐BUHAIRAN, A., GUILLIATT, A., LESTER, W., MAZURIER, C., MEYER, D., FRESSINAUD, E., BUDDE, U., WILL, K., SCHNEPPENHEIM, R., OBSER, T., MARGGRAF, O., ECKERT, E., CASTAMAN, G., RODEGHIERO, F., FEDERICI, A. B., BATLLE, J., GOUDEMAND, J., INGERSLEV, J., LETHAGEN, S., HILL, F., PEAKE, I., GOODEVE, A.
Published in Journal of thrombosis and haemostasis (01.08.2009)
Published in Journal of thrombosis and haemostasis (01.08.2009)
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Journal Article
Presurgical pharmacokinetic analysis of a von Willebrand factor/factor VIII (VWF/FVIII) concentrate in patients with von Willebrand's disease (VWD) has limited value in dosing for surgery
DI PAOLA, J., LETHAGEN, S., GILL, J., MANNUCCI, P., MANCO-JOHNSON, M., BERNSTEIN, J., NICHOLS, W. L., BERGMAN, G. E.
Published in Haemophilia : the official journal of the World Federation of Hemophilia (01.09.2011)
Published in Haemophilia : the official journal of the World Federation of Hemophilia (01.09.2011)
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Safety and pharmacokinetics of subcutaneously administered recombinant activated factor VII (rFVIIa)
TIEDE, A., FRIEDRICH, U., STENMO, C., ALLEN, G., GIANGRANDE, P., GOUDEMAND, J., HAY, C., HOLMSTRÖM, M., KLAMROTH, R., LETHAGEN, S., MCKENZIE, S., MIESBACH, W., NEGRIER, C., YUSTE, V. J., BERNTORP, E.
Published in Journal of thrombosis and haemostasis (01.06.2011)
Published in Journal of thrombosis and haemostasis (01.06.2011)
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Journal Article
Impact of plasma von Willebrand factor levels in the diagnosis of type 1 von Willebrand disease: results from a multicenter European study (MCMDM‐1VWD)
TOSETTO, A., RODEGHIERO, F., CASTAMAN, G., BERNARDI, M., BERTONCELLO, K., GOODEVE, A., FEDERICI, A. B., BATLLE, J., MEYER, D., MAZURIER, C., GOUDEMAND, J., EIKENBOOM, J., SCHNEPPENHEIM, R., BUDDE, U., INGERSLEV, J., VORLOVA, Z., HABART, D., HOLMBERG, L., LETHAGEN, S., PASI, J., HILL, F., PEAKE, I.
Published in Journal of thrombosis and haemostasis (01.04.2007)
Published in Journal of thrombosis and haemostasis (01.04.2007)
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Journal Article
On-demand vs. prophylactic treatment for severe haemophilia in Norway and Sweden: differences in treatment characteristics and outcome
Steen Carlsson, K., Höjgård, S., Glomstein, A., Lethagen, S., Schulman, S., Tengborn, L., Lindgren, A., Berntorp, E., Lindgren, B.
Published in Haemophilia : the official journal of the World Federation of Hemophilia (01.09.2003)
Published in Haemophilia : the official journal of the World Federation of Hemophilia (01.09.2003)
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