Inhibition of CDK4/CDK6 Enhances Radiosensitivity of HPV Negative Head and Neck Squamous Cell Carcinomas
Göttgens, Eva-Leonne, Bussink, Johan, Leszczynska, Katarzyna B., Peters, Hans, Span, Paul N., Hammond, Ester M.
Published in International journal of radiation oncology, biology, physics (01.11.2019)
Published in International journal of radiation oncology, biology, physics (01.11.2019)
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Journal Article
Innate immune training restores pro-reparative myeloid functions to promote remyelination in the aged central nervous system
Tiwari, Vini, Prajapati, Bharat, Asare, Yaw, Damkou, Alkmini, Ji, Hao, Liu, Lu, Naser, Nawraa, Gouna, Garyfallia, Leszczyńska, Katarzyna B., Mieczkowski, Jakub, Dichgans, Martin, Wang, Qing, Kawaguchi, Riki, Shi, Zechuan, Swarup, Vivek, Geschwind, Daniel H., Prinz, Marco, Gokce, Ozgun, Simons, Mikael
Published in Immunity (Cambridge, Mass.) (10.09.2024)
Published in Immunity (Cambridge, Mass.) (10.09.2024)
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Hypoxia-induced SETX links replication stress with the unfolded protein response
Ramachandran, Shaliny, Ma, Tiffany S., Griffin, Jon, Ng, Natalie, Foskolou, Iosifina P., Hwang, Ming-Shih, Victori, Pedro, Cheng, Wei-Chen, Buffa, Francesca M., Leszczynska, Katarzyna B., El-Khamisy, Sherif F., Gromak, Natalia, Hammond, Ester M.
Published in Nature communications (17.06.2021)
Published in Nature communications (17.06.2021)
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Journal Article
Hypoxia‐mediated regulation of DDX5 through decreased chromatin accessibility and post‐translational targeting restricts R‐loop accumulation
Leszczynska, Katarzyna B., Dzwigonska, Monika, Estephan, Hala, Moehlenbrink, Jutta, Bowler, Elizabeth, Giaccia, Amato J., Mieczkowski, Jakub, Kaminska, Bozena, Hammond, Ester M.
Published in Molecular oncology (01.07.2023)
Published in Molecular oncology (01.07.2023)
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Journal Article
KDM4A regulates HIF-1 levels through H3K9me3
Dobrynin, Grzegorz, McAllister, Tom E., Leszczynska, Katarzyna B., Ramachandran, Shaliny, Krieg, Adam J., Kawamura, Akane, Hammond, Ester M.
Published in Scientific reports (11.09.2017)
Published in Scientific reports (11.09.2017)
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Journal Article
H2A.Z histone variants facilitate HDACi-dependent removal of H3.3K27M mutant protein in pediatric high-grade glioma cells
Leszczynska, Katarzyna B., Freitas-Huhtamäki, Amanda, Jayaprakash, Chinchu, Dzwigonska, Monika, Vitorino, Francisca N.L., Horth, Cynthia, Wojnicki, Kamil, Gielniewski, Bartlomiej, Szadkowska, Paulina, Kaza, Beata, Nazarian, Javad, Ciolkowski, Maciej K., Trubicka, Joanna, Grajkowska, Wieslawa, Garcia, Benjamin A., Majewski, Jacek, Kaminska, Bozena, Mieczkowski, Jakub
Published in Cell reports (Cambridge) (27.02.2024)
Published in Cell reports (Cambridge) (27.02.2024)
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Hypoxia Potentiates the Radiation-Sensitizing Effect of Olaparib in Human Non-Small Cell Lung Cancer Xenografts by Contextual Synthetic Lethality
Jiang, Yanyan, PhD, Verbiest, Tom, MSc, Devery, Aoife M., PhD, Bokobza, Sivan M., PhD, Weber, Anika M., PhD, Leszczynska, Katarzyna B., PhD, Hammond, Ester M., PhD, Ryan, Anderson J., PhD
Published in International journal of radiation oncology, biology, physics (01.06.2016)
Published in International journal of radiation oncology, biology, physics (01.06.2016)
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Journal Article
Preclinical testing of an Atr inhibitor demonstrates improved response to standard therapies for esophageal cancer
Leszczynska, Katarzyna B, Dobrynin, Greg, Leslie, Rhea E, Ient, Jonathan, Boumelha, Adam J, Senra, Joana M, Hawkins, Maria A, Maughan, Tim, Mukherjee, Somnath, Hammond, Ester M
Published in Radiotherapy and oncology (01.11.2016)
Published in Radiotherapy and oncology (01.11.2016)
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Journal Article
Pharmacological Inhibition of ATR Can Block Autophagy through an ATR-Independent Mechanism
Bowler, Elizabeth, Skwarska, Anna, Wilson, Joseph D., Ramachandran, Shaliny, Bolland, Hannah, Easton, Alistair, Ostheimer, Christian, Hwang, Ming-Shih, Leszczynska, Katarzyna B., Conway, Stuart J., Hammond, Ester M.
Published in iScience (20.11.2020)
Published in iScience (20.11.2020)
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Journal Article
Hypoxia-induced p53 modulates both apoptosis and radiosensitivity via AKT
Leszczynska, Katarzyna B., Foskolou, Iosifina P., Abraham, Aswin G., Anbalagan, Selvakumar, Tellier, Céline, Haider, Syed, Span, Paul N., O’Neill, Eric E., Buffa, Francesca M., Hammond, Ester M.
Published in The Journal of clinical investigation (01.06.2015)
Published in The Journal of clinical investigation (01.06.2015)
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Journal Article
Hypoxia-induced p53 modulates both apoptosis and radiosensitivity via AKT
Leszczynska, Katarzyna B, Foskolou, Iosifina P, Abraham, Aswin G, Anbalagan, Selvakumar, Tellier, Céline, Haider, Syed, Span, Paul N, O'Neill, Eric E, Buffa, Francesca M, Hammond, Ester M
Published in The Journal of clinical investigation (01.06.2015)
Published in The Journal of clinical investigation (01.06.2015)
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Journal Article
Ribonucleotide Reductase Requires Subunit Switching in Hypoxia to Maintain DNA Replication
Foskolou, Iosifina P., Jorgensen, Christian, Leszczynska, Katarzyna B., Olcina, Monica M., Tarhonskaya, Hanna, Haisma, Bauke, D’Angiolella, Vincenzo, Myers, William K., Domene, Carmen, Flashman, Emily, Hammond, Ester M.
Published in Molecular cell (20.04.2017)
Published in Molecular cell (20.04.2017)
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Journal Article
WSB-1 regulates the metastatic potential of hormone receptor negative breast cancer
Poujade, Flore-Anne, Mannion, Aarren, Brittain, Nicholas, Theodosi, Andrew, Beeby, Ellie, Leszczynska, Katarzyna B., Hammond, Ester M., Greenman, John, Cawthorne, Christopher, Pires, Isabel M.
Published in British journal of cancer (01.05.2018)
Published in British journal of cancer (01.05.2018)
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Journal Article
The imidazoacridinone C-1311 induces p53-dependent senescence or p53-independent apoptosis and sensitizes cancer cells to radiation
Skwarska, Anna, Ramachandran, Shaliny, Dobrynin, Grzegorz, Leszczynska, Katarzyna B, Hammond, Ester M
Published in Oncotarget (09.05.2017)
Published in Oncotarget (09.05.2017)
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Journal Article
Identification of Histone Peptide Binding Specificity and Small-Molecule Ligands for the TRIM33α and TRIM33β Bromodomains
Sekirnik, Angelina R., Reynolds, Jessica K., See, Larissa, Bluck, Joseph P., Scorah, Amy R., Tallant, Cynthia, Lee, Bernadette, Leszczynska, Katarzyna B., Grimley, Rachel L., Storer, R. Ian, Malattia, Marta, Crespillo, Sara, Caria, Sofia, Duclos, Stephanie, Hammond, Ester M., Knapp, Stefan, Morris, Garrett M., Duarte, Fernanda, Biggin, Philip C., Conway, Stuart J.
Published in ACS chemical biology (21.10.2022)
Published in ACS chemical biology (21.10.2022)
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Journal Article
Mechanisms and consequences of ATMIN repression in hypoxic conditions: roles for p53 and HIF-1
Leszczynska, Katarzyna B., Göttgens, Eva-Leonne, Biasoli, Deborah, Olcina, Monica M., Ient, Jonathan, Anbalagan, Selvakumar, Bernhardt, Stephan, Giaccia, Amato J., Hammond, Ester M.
Published in Scientific reports (15.02.2016)
Published in Scientific reports (15.02.2016)
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Journal Article
OTME-2. Regulation of chromatin accessibility in the hypoxic tumor microenvironment of glioblastoma
Dzwigonska, Monika, Mieczkowski, Jakub, Pilanc, Paulina, Cyranowski, Salwador, Kominek, Agata, Piwocka, Katarzyna, Kaminska, Bozena, Leszczynska, Katarzyna B
Published in Neuro-oncology advances (05.07.2021)
Published in Neuro-oncology advances (05.07.2021)
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Journal Article
Hypoxia-induced p53 modulates both apoptosis and radiosensitivity via AKT
Leszczynska, Katarzyna B, Foskolou, Iosifina P, Abraham, Aswin G, Anbalagan, Selvakumar, Tellier, Celine, Haider, Syed, Span, Paul N, O'Neill, Eric E, Buffa, Francesca M, Hammond, Ester M
Published in The Journal of clinical investigation (01.07.2015)
Published in The Journal of clinical investigation (01.07.2015)
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Journal Article