Molecular Pathways: The Immunogenic Effects of Platinum-Based Chemotherapeutics
HATO, Stanleyson V, KHONG, Andrea, DE VRIES, I. Jolanda M, LESTERHUIS, W. Joost
Published in Clinical cancer research (01.06.2014)
Published in Clinical cancer research (01.06.2014)
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Chemotherapy and immunotherapy: mapping the road ahead
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Published in Current opinion in immunology (01.04.2016)
Published in Current opinion in immunology (01.04.2016)
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Sensitization to immune checkpoint blockade through activation of a STAT1/NK axis in the tumor microenvironment
Zemek, Rachael M, De Jong, Emma, Chin, Wee Loong, Schuster, Iona S, Fear, Vanessa S, Casey, Thomas H, Forbes, Cath, Dart, Sarah J, Leslie, Connull, Zaitouny, Ayham, Small, Michael, Boon, Louis, Forrest, Alistair R R, Muiri, Daithi O, Degli-Esposti, Mariapia A, Millward, Michael J, Nowak, Anna K, Lassmann, Timo, Bosco, Anthony, Lake, Richard A, Lesterhuis, W Joost
Published in Science translational medicine (17.07.2019)
Published in Science translational medicine (17.07.2019)
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Temporally restricted activation of IFNβ signaling underlies response to immune checkpoint therapy in mice
Zemek, Rachael M., Chin, Wee Loong, Fear, Vanessa S., Wylie, Ben, Casey, Thomas H., Forbes, Cath, Tilsed, Caitlin M., Boon, Louis, Guo, Belinda B., Bosco, Anthony, Forrest, Alistair R. R., Millward, Michael J., Nowak, Anna K., Lake, Richard A., Lassmann, Timo, Lesterhuis, W. Joost
Published in Nature communications (19.08.2022)
Published in Nature communications (19.08.2022)
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Synergistic effect of CTLA-4 blockade and cancer chemotherapy in the induction of anti-tumor immunity
Lesterhuis, W Joost, Salmons, Joanne, Nowak, Anna K, Rozali, Esdy N, Khong, Andrea, Dick, Ian M, Harken, Julie A, Robinson, Bruce W, Lake, Richard A
Published in PloS one (23.04.2013)
Published in PloS one (23.04.2013)
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Bilateral murine tumor models for characterizing the response to immune checkpoint blockade
Zemek, Rachael M., Fear, Vanessa S., Forbes, Cath, de Jong, Emma, Casey, Thomas H., Boon, Louis, Lassmann, Timo, Bosco, Anthony, Millward, Michael J., Nowak, Anna K., Lake, Richard A., Lesterhuis, W. Joost
Published in Nature protocols (01.05.2020)
Published in Nature protocols (01.05.2020)
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Sensitizing the Tumor Microenvironment to Immune Checkpoint Therapy
Zemek, Rachael M, Chin, Wee Loong, Nowak, Anna K, Millward, Michael J, Lake, Richard A, Lesterhuis, W Joost
Published in Frontiers in immunology (18.02.2020)
Published in Frontiers in immunology (18.02.2020)
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Programmed Death Ligand 2 in Cancer-Induced Immune Suppression
Lake, Richard A., Robinson, Bruce W. S., Hato, Stanleyson V., Rozali, Esdy N., Lesterhuis, W. Joost
Published in Clinical & developmental immunology (01.01.2012)
Published in Clinical & developmental immunology (01.01.2012)
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Targeting CD4+ T-Helper Cells Improves the Induction of Antitumor Responses in Dendritic Cell―Based Vaccination
AARNTZEN, Erik H. J. G, DE VRIES, I. Jolanda M, SCHADENDORF, Dirk, CROOCKEWIT, Alexandra, BLOKX, Willeke A. M, VAN ROSSUM, Michelle M, KWOK, William W, ADEMA, Gosse J, PUNT, Cornelis J. A, FIGDOR, Carl G, JOOST LESTERHUIS, W, SCHUURHUIS, Danita, JACOBS, JoannesF. M, BOL, Kalijn, SCHREIBELT, Gerty, MUS, Roel, DE WILT, Johannes H. W, HAANEN, John B. A. G
Published in Cancer research (Chicago, Ill.) (2013)
Published in Cancer research (Chicago, Ill.) (2013)
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Geldanamycin treatment does not result in anti-cancer activity in a preclinical model of orthotopic mesothelioma
Orozco Morales, M Lizeth, Rinaldi, Catherine A, de Jong, Emma, Lansley, Sally M, Lee, Y C Gary, Zemek, Rachael M, Bosco, Anthony, Lake, Richard A, Lesterhuis, W Joost
Published in PloS one (05.05.2023)
Published in PloS one (05.05.2023)
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Autologous monocyte-derived DC vaccination combined with cisplatin in stage III and IV melanoma patients: a prospective, randomized phase 2 trial
Boudewijns, Steve, Bloemendal, Martine, de Haas, Nienke, Westdorp, Harm, Bol, Kalijn F., Schreibelt, Gerty, Aarntzen, Erik H. J. G., Lesterhuis, W. Joost, Gorris, Mark A. J., Croockewit, Alexandra, van der Woude, Lieke L., van Rossum, Michelle M., Welzen, Marieke, de Goede, Anna, Hato, Stanleyson V., van der Graaf, Winette T. A., Punt, Cornelis J. A., Koornstra, Rutger H. T., Gerritsen, Winald R., Figdor, Carl G., de Vries, I. Jolanda M.
Published in Cancer Immunology, Immunotherapy (01.03.2020)
Published in Cancer Immunology, Immunotherapy (01.03.2020)
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Tretinoin improves the anti-cancer response to cyclophosphamide, in a model-selective manner
Tilsed, Caitlin M, Morales, M Lizeth Orozco, Zemek, Rachael M, Gordon, Brianna A, Piggott, Matthew J, Nowak, Anna K, Fisher, Scott A, Lake, Richard A, Lesterhuis, W Joost
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Published in BMC cancer (13.02.2024)
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Route of Administration Modulates the Induction of Dendritic Cell Vaccine―Induced Antigen-Specific T Cells in Advanced Melanoma Patients
JOOST LESTERHUIS, W, DE VRIES, I. Jolanda M, VAN ROSSUM, Michelle M, MUS, Roel, OYEN, Wim J. G, BOERMAN, Otto C, LUCAS, Sophie, ADEMA, Gosse J, PUNT, Cornelis J. A, FIGDOR, Carl G, SCHREIBELT, Gerty, LAMBECK, Annechien J. A, AARNTZEN, Erik H. J. G, JACOBS, Joannes F. M, SCHARENBORG, Nicole M, VAN DE RAKT, Mandy W. M. M, DE BOER, Annemiek J, CROOCKEWIT, Sandra
Published in Clinical cancer research (01.09.2011)
Published in Clinical cancer research (01.09.2011)
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Magnetic resonance tracking of dendritic cells in melanoma patients for monitoring of cellular therapy
Bulte, Jeff W M, Figdor, Carl G, de Vries, I Jolanda M, Lesterhuis, W Joost, Barentsz, Jelle O, Verdijk, Pauline, van Krieken, J Han, Boerman, Otto C, Oyen, Wim J G, Bonenkamp, Johannes J, Boezeman, Jan B, Adema, Gosse J, Scheenen, Tom W J, Punt, Cornelis J A, Heerschap, Arend
Published in Nature biotechnology (01.11.2005)
Published in Nature biotechnology (01.11.2005)
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Dexamethasone differentially depletes tumour and peripheral blood lymphocytes and can impact the efficacy of chemotherapy/checkpoint blockade combination treatment
Aston, Wayne J., Hope, Danika E., Cook, Alistair M., Boon, Louis, Dick, Ian, Nowak, Anna K., Lake, Richard A., Lesterhuis, W. Joost
Published in Oncoimmunology (02.11.2019)
Published in Oncoimmunology (02.11.2019)
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Skin-Test Infiltrating Lymphocytes Early Predict Clinical Outcome of Dendritic Cell―Based Vaccination in Metastatic Melanoma
AARNTZEN, Erik H. J. G, BOL, Kalijn, SCHREIBELT, Gerty, JACOBS, Joannes F. M, JOOST LESTERHUIS, W, VAN ROSSUM, Michelle M, ADEMA, Gosse J, FIGDOR, Carl G, PUNT, Cornelis J. A, DE VRIES, I. Jolanda M
Published in Cancer research (Chicago, Ill.) (01.12.2012)
Published in Cancer research (Chicago, Ill.) (01.12.2012)
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Local therapy with combination TLR agonists stimulates systemic anti-tumor immunity and sensitizes tumors to immune checkpoint blockade
Rwandamuriye, Francois Xavier, Wang, Tao, Zhang, Hanfu, Elaskalani, Omar, Kuster, Jorren, Ye, Xueting, Vitali, Breana, Schreurs, Juliët, Orozco Morales, M Lizeth, Norret, Marck, Evans, Cameron W, Zemek, Rachael M, Iyer, K Swaminathan, Lesterhuis, W Joost, Wylie, Ben
Published in Oncoimmunology (2024)
Published in Oncoimmunology (2024)
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