Immune checkpoint inhibitors for the treatment of MSI-H/MMR-D colorectal cancer and a perspective on resistance mechanisms
Sahin, Ibrahim Halil, Akce, Mehmet, Alese, Olatunji, Shaib, Walid, Lesinski, Gregory B., El-Rayes, Bassel, Wu, Christina
Published in British journal of cancer (12.11.2019)
Published in British journal of cancer (12.11.2019)
Get full text
Journal Article
Pancreatic Cancer-Associated Stellate Cells Promote Differentiation of Myeloid-Derived Suppressor Cells in a STAT3-Dependent Manner
MACE, Thomas A, AMEEN, Zeenath, BLOOMSTON, Mark, LESINSKI, Gregory B, COLLINS, Amy, WOJCIK, Sylwia, MAIR, Markus, YOUNG, Gregory S, FUCHS, James R, EUBANK, Tim D, FRANKEL, Wendy L, BEKAII-SAAB, Tanios
Published in Cancer research (Chicago, Ill.) (15.05.2013)
Published in Cancer research (Chicago, Ill.) (15.05.2013)
Get full text
Journal Article
Inhibition of HSP90 overcomes resistance to chemotherapy and radiotherapy in pancreatic cancer
Nagaraju, Ganji Purnachandra, Zakka, Katerina M., Landry, Jerome C., Shaib, Walid L., Lesinski, Gregory B., El‐Rayes, Bassel F.
Published in International journal of cancer (15.09.2019)
Published in International journal of cancer (15.09.2019)
Get full text
Journal Article
The Potential of CAR T Cell Therapy in Pancreatic Cancer
Akce, Mehmet, Zaidi, Mohammad Y, Waller, Edmund K, El-Rayes, Bassel F, Lesinski, Gregory B
Published in Frontiers in immunology (25.09.2018)
Published in Frontiers in immunology (25.09.2018)
Get full text
Journal Article
Lipocalin-2 Promotes Pancreatic Ductal Adenocarcinoma by Regulating Inflammation in the Tumor Microenvironment
Gomez-Chou, Sobeyda B, Swidnicka-Siergiejko, Agnieszka Katarzyna, Badi, Niharika, Chavez-Tomar, Myrriah, Lesinski, Gregory B, Bekaii-Saab, Tanios, Farren, Matthew R, Mace, Thomas A, Schmidt, Carl, Liu, Yan, Deng, Defeng, Hwang, Rosa F, Zhou, Liran, Moore, Todd, Chatterjee, Deyali, Wang, Huamin, Leng, Xiaohong, Arlinghaus, Ralph B, Logsdon, Craig D, Cruz-Monserrate, Zobeida
Published in Cancer research (Chicago, Ill.) (15.05.2017)
Published in Cancer research (Chicago, Ill.) (15.05.2017)
Get full text
Journal Article
Enhanced bioavailability of lycopene when consumed as cis‐isomers from tangerine compared to red tomato juice, a randomized, cross‐over clinical trial
Cooperstone, Jessica L, Ralston, Robin A, Riedl, Ken M, Haufe, Thomas C, Schweiggert, Ralf M, King, Samantha A, Timmers, Cynthia D, Francis, David M, Lesinski, Gregory B, Clinton, Steven K, Schwartz, Steven J
Published in Molecular nutrition & food research (01.04.2015)
Published in Molecular nutrition & food research (01.04.2015)
Get full text
Journal Article
Randomized Phase 2 Trial of the Oncolytic Virus Pelareorep (Reolysin) in Upfront Treatment of Metastatic Pancreatic Adenocarcinoma
Noonan, Anne M, Farren, Matthew R, Geyer, Susan M, Huang, Ying, Tahiri, Sanaa, Ahn, Daniel, Mikhail, Sameh, Ciombor, Kristen K, Pant, Shubham, Aparo, Santiago, Sexton, Jennifer, Marshall, John L, Mace, Thomas A, Wu, Christina S, El-Rayes, Bassel, Timmers, Cynthia D, Zwiebel, James, Lesinski, Gregory B, Villalona-Calero, Miguel A, Bekaii-Saab, Tanios S
Published in Molecular therapy (01.06.2016)
Published in Molecular therapy (01.06.2016)
Get full text
Journal Article
Preclinical Investigation of the Novel Histone Deacetylase Inhibitor AR-42 in the Treatment of Cancer-Induced Cachexia
Tseng, Yu-Chou, Kulp, Samuel K, Lai, I-Lu, Hsu, En-Chi, He, Wei A, Frankhouser, David E, Yan, Pearlly S, Mo, Xiaokui, Bloomston, Mark, Lesinski, Gregory B, Marcucci, Guido, Guttridge, Denis C, Bekaii-Saab, Tanios, Chen, Ching-Shih
Published in JNCI : Journal of the National Cancer Institute (01.12.2015)
Published in JNCI : Journal of the National Cancer Institute (01.12.2015)
Get full text
Journal Article
MEK inhibition suppresses B regulatory cells and augments anti-tumor immunity
Yarchoan, Mark, Mohan, Aditya A, Dennison, Lauren, Vithayathil, Teena, Ruggieri, Amanda, Lesinski, Gregory B, Armstrong, Todd D, Azad, Nilofer S, Jaffee, Elizabeth M
Published in PloS one (31.10.2019)
Published in PloS one (31.10.2019)
Get full text
Journal Article
Hypoxia induces the overexpression of microRNA-21 in pancreatic cancer cells
Mace, Thomas A., PhD, Collins, Amy L., MD, Wojcik, Sylwia E., MS, Croce, Carlo M., MD, Lesinski, Gregory B., PhD, MPH, Bloomston, Mark, MD, FACS
Published in The Journal of surgical research (01.10.2013)
Published in The Journal of surgical research (01.10.2013)
Get full text
Journal Article
Inhibition of Jak/STAT signaling reduces the activation of pancreatic stellate cells in vitro and limits caerulein-induced chronic pancreatitis in vivo
Komar, Hannah M., Serpa, Gregory, Kerscher, Claire, Schwoegl, Erin, Mace, Thomas A., Jin, Ming, Yang, Ming-Chen, Chen, Ching-Shih, Bloomston, Mark, Ostrowski, Michael C., Hart, Phil A., Conwell, Darwin L., Lesinski, Gregory B.
Published in Scientific reports (11.05.2017)
Published in Scientific reports (11.05.2017)
Get full text
Journal Article
Statin drugs enhance responses to immune checkpoint blockade in head and neck cancer models
Kansal, Vikash, Burnham, Andre J, Kinney, Brendan L C, Saba, Nabil, Paulos, Chrystal, Lesinski, Gregory B, Buchwald, Zachary S, Schmitt, Nicole C
Published in Journal for immunotherapy of cancer (01.01.2023)
Published in Journal for immunotherapy of cancer (01.01.2023)
Get full text
Journal Article
Combined IL6 and CCR2 blockade potentiates antitumor activity of NK cells in HPV-negative head and neck cancer
Yang, Fan, Yuan, Chenyang, Chen, Fanghui, Qin, Zhaohui S, Schmitt, Nicole C, Lesinski, Gregory B, Saba, Nabil F, Teng, Yong
Published in Journal of experimental & clinical cancer research (12.03.2024)
Published in Journal of experimental & clinical cancer research (12.03.2024)
Get full text
Journal Article
Myeloid-Derived Suppressor Cell Inhibition of the IFN Response in Tumor-Bearing Mice
MUNDY-BOSSE, Bethany L, LESINSKI, Gregory B, KREINER, Melanie, YOUNG, Gregory, GUTTRIDGE, Denis C, CARSON, William E, JAIME-RAMIREZ, Alena C, BENNINGER, Kristen, KHAN, Mahmood, KUPPUSAMY, Periannan, GUENTERBERG, Kristan, VIDYA KONDADASULA, Sri, RAY CHAUDHURY, Abhik, LA PERLE, Krista M
Published in Cancer research (Chicago, Ill.) (01.08.2011)
Published in Cancer research (Chicago, Ill.) (01.08.2011)
Get full text
Journal Article
Targeting vasoactive intestinal peptide-mediated signaling enhances response to immune checkpoint therapy in pancreatic ductal adenocarcinoma
Ravindranathan, Sruthi, Passang, Tenzin, Li, Jian-Ming, Wang, Shuhua, Dhamsania, Rohan, Ware, Michael Brandon, Zaidi, Mohammad Y., Zhu, Jingru, Cardenas, Maria, Liu, Yuan, Gumber, Sanjeev, Robinson, Brian, Sen-Majumdar, Anish, Zhang, Hanwen, Chandrakasan, Shanmuganathan, Kissick, Haydn, Frey, Alan B., Thomas, Susan N., El-Rayes, Bassel F., Lesinski, Gregory B., Waller, Edmund K.
Published in Nature communications (27.10.2022)
Published in Nature communications (27.10.2022)
Get full text
Journal Article
Phosphoinositide 3-Kinase Signaling Can Modulate MHC Class I and II Expression
Chandrasekaran, Sanjay, Sasaki, Maiko, Scharer, Christopher D, Kissick, Haydn T, Patterson, Dillon G, Magliocca, Kelly R, Seykora, John T, Sapkota, Bishu, Gutman, David A, Cooper, Lee A, Lesinski, Gregory B, Waller, Edmund K, Thomas, Susan N, Kotenko, Sergei V, Boss, Jeremy M, Moreno, Carlos S, Swerlick, Robert A, Pollack, Brian P
Published in Molecular cancer research (01.12.2019)
Published in Molecular cancer research (01.12.2019)
Get full text
Journal Article
Novel small molecule XPO1/CRM1 inhibitors induce nuclear accumulation of TP53, phosphorylated MAPK and apoptosis in human melanoma cells
Yang, Jennifer, Bill, Matthew A, Young, Gregory S, La Perle, Krista, Landesman, Yosef, Shacham, Sharon, Kauffman, Michael, Senapedis, William, Kashyap, Trinayan, Saint-Martin, Jean-Richard, Kendra, Kari, Lesinski, Gregory B
Published in PloS one (24.07.2014)
Published in PloS one (24.07.2014)
Get full text
Journal Article
Mirage or long-awaited oasis: reinvigorating T-cell responses in pancreatic cancer
Ware, Michael Brandon, El-Rayes, Bassel F, Lesinski, Gregory B
Published in Journal for immunotherapy of cancer (01.08.2020)
Published in Journal for immunotherapy of cancer (01.08.2020)
Get full text
Journal Article