Cell–cell fusion of mesenchymal cells with distinct differentiations triggers genomic and transcriptomic remodelling toward tumour aggressiveness
Delespaul, Lucile, Gélabert, Caroline, Lesluyes, Tom, Le Guellec, Sophie, Pérot, Gaëlle, Leroy, Laura, Baud, Jessica, Merle, Candice, Lartigue, Lydia, Chibon, Frédéric
Published in Scientific reports (10.12.2020)
Published in Scientific reports (10.12.2020)
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Medium levels of transcription and replication related chromosomal instability are associated with poor clinical outcome
Benhaddou, Ataaillah, Gaston, Laetitia, Pérot, Gaëlle, Desplat, Nelly, Leroy, Laura, Le Guellec, Sophie, Ben Haddou, Mohamed, Rochaix, Philippe, Valentin, Thibaud, Ferron, Gwenaël, Chevreau, Christine, Bui, Binh, Stoeckle, Eberhard, Le Cesne, Axel, Piperno-Neumann, Sophie, Collin, Françoise, Firmin, Nelly, De Pinieux, Gonzague, Coindre, Jean-Michel, Blay, Jean-Yves, Chibon, Frédéric
Published in Scientific reports (06.12.2021)
Published in Scientific reports (06.12.2021)
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Association of the Lung Immune Prognostic Index With Immune Checkpoint Inhibitor Outcomes in Patients With Advanced Non-Small Cell Lung Cancer
Mezquita, Laura, Auclin, Edouard, Ferrara, Roberto, Charrier, Melinda, Remon, Jordi, Planchard, David, Ponce, Santiago, Ares, Luis Paz, Leroy, Laura, Audigier-Valette, Clarisse, Felip, Enriqueta, Zerón-Medina, Jorge, Garrido, Pilar, Brosseau, Solenn, Zalcman, Gérard, Mazieres, Julien, Caramela, Caroline, Lahmar, Jihene, Adam, Julien, Chaput, Nathalie, Soria, Jean Charles, Besse, Benjamin
Published in JAMA oncology (01.03.2018)
Published in JAMA oncology (01.03.2018)
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Journal Article
Genetic determinants of response to fibroblast growth factor receptor inhibitors in solid tumours
Leroy, Laura, Cousin, Sophie, Italiano, Antoine
Published in European journal of cancer (1990) (01.08.2017)
Published in European journal of cancer (1990) (01.08.2017)
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Journal Article
Remarkable Response to Ceritinib and Brigatinib in an Anaplastic Lymphoma Kinase-Rearranged Anaplastic Thyroid Carcinoma Previously Treated with Crizotinib
Leroy, Laura, Bonhomme, Benjamin, Le Moulec, Sylvestre, Soubeyran, Isabelle, Italiano, Antoine, Godbert, Yann
Published in Thyroid (New York, N.Y.) (01.02.2020)
Published in Thyroid (New York, N.Y.) (01.02.2020)
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Journal Article
Hyperprogressive Disease in Patients With Advanced Non-Small Cell Lung Cancer Treated With PD-1/PD-L1 Inhibitors or With Single-Agent Chemotherapy
Ferrara, Roberto, Mezquita, Laura, Texier, Matthieu, Lahmar, Jihene, Audigier-Valette, Clarisse, Tessonnier, Laurent, Mazieres, Julien, Zalcman, Gerard, Brosseau, Solenn, Le Moulec, Sylvestre, Leroy, Laura, Duchemann, Boris, Lefebvre, Corentin, Veillon, Remi, Westeel, Virginie, Koscielny, Serge, Champiat, Stephane, Ferté, Charles, Planchard, David, Remon, Jordi, Boucher, Marie-Eve, Gazzah, Anas, Adam, Julien, Bria, Emilio, Tortora, Giampaolo, Soria, Jean-Charles, Besse, Benjamin, Caramella, Caroline
Published in JAMA oncology (01.11.2018)
Published in JAMA oncology (01.11.2018)
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Journal Article
TROP2 expression and response to immune checkpoint inhibition in patients with advanced non-small cell lung cancer
Italiano, Antoine, Leroy, Laura, Guegan, Jean-Philippe, Cousin, Sophie, Peyraud, Florent, Cabart, Mathilde, Chomy, Francois, Vanhersecke, Lucile, Bessede, Alban
Published in Journal of clinical oncology (01.06.2023)
Published in Journal of clinical oncology (01.06.2023)
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Journal Article
Single- and multi-site radiomics may improve overall survival prediction for patients with metastatic lung adenocarcinoma
Masson-Grehaigne, Cécile, Lafon, Mathilde, Palussière, Jean, Leroy, Laura, Bonhomme, Benjamin, Jambon, Eva, Italiano, Antoine, Cousin, Sophie, Crombé, Amandine
Published in Diagnostic and interventional imaging (26.08.2024)
Published in Diagnostic and interventional imaging (26.08.2024)
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Journal Article
Enhancing Immunotherapy Response Prediction in Metastatic Lung Adenocarcinoma: Leveraging Shallow and Deep Learning with CT-Based Radiomics across Single and Multiple Tumor Sites
Masson-Grehaigne, Cécile, Lafon, Mathilde, Palussière, Jean, Leroy, Laura, Bonhomme, Benjamin, Jambon, Eva, Italiano, Antoine, Cousin, Sophie, Crombé, Amandine
Published in Cancers (08.07.2024)
Published in Cancers (08.07.2024)
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Journal Article
Genome remodeling upon mesenchymal tumor cell fusion contributes to tumor progression and metastatic spread
Lartigue, Lydia, Merle, Candice, Lagarde, Pauline, Delespaul, Lucile, Lesluyes, Tom, Le Guellec, Sophie, Pérot, Gaelle, Leroy, Laura, Coindre, Jean-Michel, Chibon, Frédéric
Published in Oncogene (21.05.2020)
Published in Oncogene (21.05.2020)
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Journal Article
Antitumor Effects of PRMT5 Inhibition in Sarcomas
Verbeke, Stéphanie, Bourdon, Aurélien, Guegan, Jean-Philippe, Leroy, Laura, Chaire, Vanessa, Richard, Elodie, Bessede, Alban, Italiano, Antoine
Published in Cancer research communications (02.11.2023)
Published in Cancer research communications (02.11.2023)
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Journal Article
Abstract 3937: PRMT5 inhibition suppress soft tissue sarcomas tumorigenicity through the regulation of glucose metabolism
Verbeke, Stephanie, Leroy, Laura, Bourdon, Aurelien, Chaire, Vanessa, Richard, Elodie, Guegan, Jean-Philippe, Bessede, Alban, Italiano, Antoine
Published in Cancer research (Chicago, Ill.) (15.06.2022)
Published in Cancer research (Chicago, Ill.) (15.06.2022)
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Fast-progression (FP), hyper-progression (HPD) and early deaths (ED) in advanced non-small cell lung cancer (NSCLC) patients (pts) upon PD-(L)-1 blockade (IO)
Ferrara, Roberto, Mezquita, Laura, Texier, Matthieu, Lahmar, Jihene, Audigier-Valette, Clarisse, Tessonnier, Laurent, Mazieres, Julien, Brosseau, Solenn, Leroy, Laura, Duchemann, Boris, Lefebvre, Corentin, Veillon, Remi, Westeel, Virginie, Champiat, Stephane, Planchard, David, Remon, Jordi, Gazzah, Anas, Soria, Jean-Charles, Caramella, Caroline, Besse, Benjamin
Published in Journal of clinical oncology (20.05.2019)
Published in Journal of clinical oncology (20.05.2019)
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Journal Article
ATRX Alteration Contributes to Tumor Growth and Immune Escape in Pleomorphic Sarcomas
Darmusey, Lucie, Pérot, Gaëlle, Thébault, Noémie, Le Guellec, Sophie, Desplat, Nelly, Gaston, Laëtitia, Delespaul, Lucile, Lesluyes, Tom, Darbo, Elodie, Gomez-Brouchet, Anne, Richard, Elodie, Baud, Jessica, Leroy, Laura, Coindre, Jean-Michel, Blay, Jean-Yves, Chibon, Frédéric
Published in Cancers (29.04.2021)
Published in Cancers (29.04.2021)
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Journal Article
Distinct Cellular Origins and Differentiation Process Account for Distinct Oncogenic and Clinical Behaviors of Leiomyosarcomas
Darbo, Elodie, Pérot, Gaëlle, Darmusey, Lucie, Le Guellec, Sophie, Leroy, Laura, Gaston, Laëtitia, Desplat, Nelly, Thébault, Noémie, Merle, Candice, Rochaix, Philippe, Valentin, Thibaud, Ferron, Gwenaël, Chevreau, Christine, Bui, Binh, Stoeckle, Eberhard, Ranchere-Vince, Dominique, Méeus, Pierre, Terrier, Philippe, Piperno-Neumann, Sophie, Collin, Françoise, De Pinieux, Gonzague, Duffaud, Florence, Coindre, Jean-Michel, Blay, Jean-Yves, Chibon, Frédéric
Published in Cancers (15.01.2023)
Published in Cancers (15.01.2023)
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The hereditary N363K POLE exonuclease mutant extends PPAP tumor spectrum to glioblastomas by causing DNA damage and aneuploidy in addition to increased mismatch mutagenicity
Labrousse, Guillaume, Vande Perre, Pierre, Parra, Genis, Jaffrelot, Marion, Leroy, Laura, Chibon, Frederic, Escudie, Frederic, Selves, Janick, Hoffmann, Jean-Sebastien, Guimbaud, Rosine, Lutzmann, Malik
Published in NAR cancer (01.06.2023)
Published in NAR cancer (01.06.2023)
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Journal Article
Comparison of Fast-Progression, Hyperprogressive Disease, and Early Deaths in Advanced Non-Small-Cell Lung Cancer Treated With PD-1/PD-L1 Inhibitors or Chemotherapy
Ferrara, Roberto, Mezquita, Laura, Texier, Matthieu, Lahmar, Jihene, Audigier-Valette, Clarisse, Tessonnier, Laurent, Mazieres, Julien, Zalcman, Gerard, Brosseau, Solenn, Le Moulec, Sylvestre, Leroy, Laura, Duchemann, Boris, Lefebvre, Corentin, Veillon, Remi, Westeel, Virginie, Koscielny, Serge, Champiat, Stephane, Ferté, Charles, Planchard, David, Remon, Jordi, Boucher, Marie Eve, Gazzah, Anas, Adam, Julien, Lo Russo, Giuseppe, Signorelli, Diego, Garassino, Marina Chiara, Soria, Jean Charles, Caramella, Caroline, Besse, Benjamin
Published in JCO precision oncology (01.11.2020)
Published in JCO precision oncology (01.11.2020)
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Principles, modalities and indications of the administration of Radium in cancers, focus on metastatic prostate cancer: State of arts
Bertolaso, Pauline, Leroy, Laura, Gross-Goupil, Marine, Aupee, Olivier, Ravaud, Alain, Roubaud, Guilhem, Cazeau, Anne-Laure, Le Moulec, Sylvestre
Published in Bulletin du cancer (01.09.2017)
Published in Bulletin du cancer (01.09.2017)
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Thrombopénie auto-immune fatale au décours d’un traitement par un anticorps anti-PDL-1
Leroy, Laura, Blouin, Laura, Le Moulec, Sylvestre, Durrieu, Françoise, Bijou, Fontanet, Lafarge, Xavier
Published in Transfusion clinique et biologique : journal de la Société française de transfusion sanguine (01.09.2017)
Published in Transfusion clinique et biologique : journal de la Société française de transfusion sanguine (01.09.2017)
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Journal Article
ATRX alteration contributes to tumor growth and immune escape in pleomorphic sarcomas
Darmusey, Lucie, Pérot, Gaëlle, Thébault, Noémie, Sophie Le Guellec, Desplat, Nelly, Gaston, Laëtitia, Delespaul, Lucile, Lesluyes, Tom, Darbo, Elodie, Gomez-Brouchet, Anne, Elodie, Richard, Baud, Jessica, Leroy, Laura, Jean-Michel Coindre, Blay, Jean-Yves, Chibon, Frédéric
Published in bioRxiv (15.01.2021)
Published in bioRxiv (15.01.2021)
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