394 Sensitivity of acute myeloid leukemia cells to a urokinase-activated anthrax lethal toxin (PrAgU2/lf) is dependent on uPAR expression and phospho-MEK1/2 levels
Bekdash, A, Liu, S.H, Leppla, S.H, Frankel, A.E, Abi-Habib, R
Published in European journal of cancer (1990) (01.11.2014)
Published in European journal of cancer (1990) (01.11.2014)
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Fusions of anthrax toxin lethal factor to the ADP-ribosylation domain of Pseudomonas exotoxin A are potent cytotoxins which are translocated to the cytosol of mammalian cells
ARORA, N, KLIMPEL, K. R, YOGENDRA SINGH, LEPPLA, S. H
Published in The Journal of biological chemistry (05.08.1992)
Published in The Journal of biological chemistry (05.08.1992)
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Journal Article
Functional mapping of anthrax toxin lethal factor by in-frame insertion mutagenesis
QUINN, C. P, SINGH, Y, KLIMPEL, K. R, LEPPLA, S. H
Published in The Journal of biological chemistry (25.10.1991)
Published in The Journal of biological chemistry (25.10.1991)
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Functional characterization of protease-treated Bacillus anthracis protective antigen
NOVAK, J. M, STEIN, M.-P, LITTLE, S. F, LEPPLA, S. H, FRIEDLANDER, A. M
Published in The Journal of biological chemistry (25.08.1992)
Published in The Journal of biological chemistry (25.08.1992)
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Journal Article
Protection against anthrax toxin by recombinant antibody fragments correlates with antigen affinity
Georgiou, George, Maynard, Jennifer A, Maassen, Catharina B.M, Leppla, Stephen H, Brasky, Kathleen, Patterson, Jean L, Iverson, Brent L
Published in Nature biotechnology (01.06.2002)
Published in Nature biotechnology (01.06.2002)
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Journal Article
In Vitro Processing of Anthrax Toxin Protective Antigen by Recombinant PC1(SPC3) and Bovine Intermediate Lobe Secretory Vesicle Membranes
Friedman, T.C., Gordon, V.M., Leppla, S.H., Klimpel, K.R., Birch, N.P., Loh, Y.P.
Published in Archives of biochemistry and biophysics (10.01.1995)
Published in Archives of biochemistry and biophysics (10.01.1995)
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Human furin is a calcium-dependent serine endoprotease that recognizes the sequence Arg-X-X-Arg and efficiently cleaves anthrax toxin protective antigen
MOLLOY, S. S, BRESNAHAN, P. A, LEPPLA, S. H, KLIMPEL, K. R, THOMAS, G
Published in The Journal of biological chemistry (15.08.1992)
Published in The Journal of biological chemistry (15.08.1992)
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Receptor-mediated internalization and degradation of diphtheria toxin by monkey kidney cells
Dorland, R B, Middlebrook, J L, Leppla, S H
Published in The Journal of biological chemistry (25.11.1979)
Published in The Journal of biological chemistry (25.11.1979)
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Characterization of lethal factor binding and cell receptor binding domains of protective antigen of Bacillus anthracis using monoclonal antibodies
Little, S.F, Novak, J.M, Lowe, J.R, Leppla, S.H, Singh, Y, Klimpel, K.R, Lidgerding, B.C, Friedlander, A.M
Published in Microbiology (Society for General Microbiology) (01.03.1996)
Published in Microbiology (Society for General Microbiology) (01.03.1996)
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Cloning and characterization of a gene whose product is a trans-activator of anthrax toxin synthesis
Uchida, I, Hornung, J.M, Thorne, C.B, Klimpel, K.R, Leppla, S.H
Published in Journal of Bacteriology (01.09.1993)
Published in Journal of Bacteriology (01.09.1993)
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Delivery of Antigens to the MHC Class I Pathway Using Bacterial Toxins
Goletz, T.J, Klimpel, K.R, Leppla, S.H, Keith, J.M, Berzofsky, J.A
Published in Human Immunology (01.05.1997)
Published in Human Immunology (01.05.1997)
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Peptide toxins directed at the matrix dissolution systems of cancer cells
Frankel, Arthur E, Bugge, Thomas H, Liu, Shihui, Vallera, Daniel A, Leppla, Stephen H
Published in Protein and peptide letters (01.02.2002)
Published in Protein and peptide letters (01.02.2002)
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