Cytolethal distending toxin B as a cell-killing component of tumor-targeted anthrax toxin fusion proteins
Bachran, C, Hasikova, R, Leysath, C E, Sastalla, I, Zhang, Y, Fattah, R J, Liu, S, Leppla, S H
Published in Cell death & disease (01.01.2014)
Published in Cell death & disease (01.01.2014)
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Crystal structure of the anthrax toxin protective antigen
Petosa, Carlo, Collier, R. John, Klimpel, Kurt R, Leppla, Stephen H, Liddington, Robert C
Published in Nature (London) (27.02.1997)
Published in Nature (London) (27.02.1997)
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Proteolytic Inactivation of MAP-Kinase-Kinase by Anthrax Lethal Factor
Duesbery, Nicholas S., Webb, Craig P., Leppla, Stephen H., Gordon, Valery M., Klimpel, Kurt R., Copeland, Terry D., Ahn, Natalie G., Oskarsson, Marianne K., Fukasawa, Kenji, Paull, Ken D., George F. Vande Woude
Published in Science (American Association for the Advancement of Science) (01.05.1998)
Published in Science (American Association for the Advancement of Science) (01.05.1998)
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Tumor cell-selective cytotoxicity of matrix metalloproteinase-activated anthrax toxin
SHIHUI LIU, NETZEL-ARNETT, Sarah, BIRKEDAL-HANSEN, Henning, LEPPLA, Stephen H
Published in Cancer research (Chicago, Ill.) (01.11.2000)
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Published in Cancer research (Chicago, Ill.) (01.11.2000)
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326 Acute Myeloid Leukemia (AML) Cell Lines Are Sensitive to the Anthrax Lethal Toxin (LeTx)-Mediated Inhibition of the MAPK Pathway
Abi-Habib, R, Kassab, E, Darwish, M, Timsah, Z, Liu, S, Leppla, S, Frankel, A
Published in European journal of cancer (1990) (01.11.2012)
Published in European journal of cancer (1990) (01.11.2012)
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Suppression of Ras-Mediated Transformation and Inhibition of Tumor Growth and Angiogenesis by Anthrax Lethal Factor, a Proteolytic Inhibitor of Multiple MEK Pathways
Duesbery, N. S., Resau, J., Webb, C. P., Koochekpour, S., H.-M. Koo, Leppla, S. H., G. F. Vande Woude
Published in Proceedings of the National Academy of Sciences - PNAS (27.03.2001)
Published in Proceedings of the National Academy of Sciences - PNAS (27.03.2001)
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Protection against Anthrax Lethal Toxin Challenge by Genetic Immunization with a Plasmid Encoding the Lethal Factor Protein
PRICE, Brian M, LINER, Adriane L, SUKJOON PARK, LEPPLA, Stephen H, MATECZUN, Alfred, GALLOWAY, Darrell R
Published in Infection and Immunity (01.07.2001)
Published in Infection and Immunity (01.07.2001)
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Human furin is a calcium-dependent serine endoprotease that recognizes the sequence Arg-X-X-Arg and efficiently cleaves anthrax toxin protective antigen
MOLLOY, S. S, BRESNAHAN, P. A, LEPPLA, S. H, KLIMPEL, K. R, THOMAS, G
Published in The Journal of biological chemistry (15.08.1992)
Published in The Journal of biological chemistry (15.08.1992)
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Anthrax Toxin Protective Antigen is Activated by a Cell Surface Protease with the Sequence Specificity and Catalytic Properties of Furin
Klimpel, Kurt R., Molloy, Sean S., Thomas, Gary, Leppla, Stephen H.
Published in Proceedings of the National Academy of Sciences - PNAS (01.11.1992)
Published in Proceedings of the National Academy of Sciences - PNAS (01.11.1992)
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Crystal structure of the anthrax lethal factor
Liddington, Robert C, Pannifer, Andrew D, Wong, Thiang Yian, Schwarzenbacher, Robert, Renatus, Martin, Petosa, Carlo, Bienkowska, Jadwiga, Lacy, D. Borden, Collier, R. John, Park, Sukjoon, Leppla, Stephen H, Hanna, Philip
Published in Nature (London) (08.11.2001)
Published in Nature (London) (08.11.2001)
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The structural basis for substrate and inhibitor selectivity of the anthrax lethal factor
Liddington, Robert C, Cantley, Lewis C, Turk, Benjamin E, Wong, Thiang Yian, Schwarzenbacher, Robert, Jarrell, Emily T, Leppla, Stephen H, Collier, R John
Published in Nature structural & molecular biology (01.01.2004)
Published in Nature structural & molecular biology (01.01.2004)
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Targeting of Tumor Cells by Cell Surface Urokinase Plasminogen Activator-dependent Anthrax Toxin
Liu, Shihui, Bugge, Thomas H., Leppla, Stephen H.
Published in The Journal of biological chemistry (25.05.2001)
Published in The Journal of biological chemistry (25.05.2001)
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