Search Results - "Lepistö, Matti" :: K.UTB vyhledávací portál | TBU Library Retrieval Portal

Ligand Binding Mechanism in Steroid Receptors: From Conserved Plasticity to Differential Evolutionary Constraints

Ligand Binding Mechanism in Steroid Receptors: From Conserved Plasticity to Differential Evolutionary Constraints

by Edman, Karl, Hosseini, Ali, Bjursell, Magnus K., Aagaard, Anna, Wissler, Lisa, Gunnarsson, Anders, Kaminski, Tim, Köhler, Christian, Bäckström, Stefan, Jensen, Tina J., Cavallin, Anders, Karlsson, Ulla, Nilsson, Ewa, Lecina, Daniel, Takahashi, Ryoji, Grebner, Christoph, Geschwindner, Stefan, Lepistö, Matti, Hogner, Anders C., Guallar, Victor
Published in Structure (London) (01.12.2015)

Get full text

Journal Article Publication

Discovery of a Novel Oral Glucocorticoid Receptor Modulator (AZD9567) with Improved Side Effect Profile

by Ripa, Lena, Edman, Karl, Dearman, Matthew, Edenro, Goran, Hendrickx, Ramon, Ullah, Victoria, Chang, Hui-Fang, Lepistö, Matti, Chapman, Dave, Geschwindner, Stefan, Wissler, Lisa, Svanberg, Petter, Lawitz, Karolina, Malmberg, Jesper, Nikitidis, Antonios, Olsson, Roine I, Bird, James, Llinas, Antoni, Hegelund-Myrbäck, Tove, Berger, Markus, Thorne, Philip, Harrison, Richard, Köhler, Christian, Drmota, Tomas
Published in Journal of medicinal chemistry (08.03.2018)

Get full text

Journal Article

Synthesis and Functionalization of Cyclic Sulfonimidamides: A Novel Chiral Heterocyclic Carboxylic Acid Bioisostere

Synthesis and Functionalization of Cyclic Sulfonimidamides: A Novel Chiral Heterocyclic Carboxylic Acid Bioisostere

by Pemberton, Nils, Graden, Henrik, Evertsson, Emma, Bratt, Emma, Lepistö, Matti, Johannesson, Petra, Svensson, Per H
Published in ACS medicinal chemistry letters (12.07.2012)

Get full text

Journal Article

Identification of indole inhibitors of human hematopoietic prostaglandin D2 synthase (hH-PGDS)

Identification of indole inhibitors of human hematopoietic prostaglandin D2 synthase (hH-PGDS)

by Edfeldt, Fredrik, Evenäs, Johan, Lepistö, Matti, Ward, Alison, Petersen, Jens, Wissler, Lisa, Rohman, Mattias, Sivars, Ulf, Svensson, Karin, Perry, Matthew, Feierberg, Isabella, Zhou, Xiao-Hong, Hansson, Thomas, Narjes, Frank
Published in Bioorganic & medicinal chemistry letters (15.06.2015)

Get full text

Journal Article

Backbone 1H, 13C, and 15N resonance assignments of the ligand binding domain of the human wildtype glucocorticoid receptor and the F602S mutant variant

Backbone 1H, 13C, and 15N resonance assignments of the ligand binding domain of the human wildtype glucocorticoid receptor and the F602S mutant variant

by Köhler, Christian, Carlström, Göran, Tångefjord, Stefan, Papavoine, Tineke, Lepistö, Matti, Edman, Karl, Akke, Mikael
Published in Biomolecular NMR assignments (01.10.2018)

Get full text

Journal Article

Novel conserved hydrolase domain in the CLCA family of alleged calcium-activated chloride channels

Novel conserved hydrolase domain in the CLCA family of alleged calcium-activated chloride channels

by Pawłowski, Krzysztof, Lepistö, Matti, Meinander, Nina, Sivars, Ulf, Varga, Mikael, Wieslander, Elisabet
Published in Proteins, structure, function, and bioinformatics (15.05.2006)

Get full text

Journal Article

Discovery of the Potent and Selective Inhaled Janus Kinase 1 Inhibitor AZD4604 and Its Preclinical Characterization

Discovery of the Potent and Selective Inhaled Janus Kinase 1 Inhibitor AZD4604 and Its Preclinical Characterization

by Nilsson, Magnus, Berggren, Kristina, Berglund, Susanne, Cerboni, Silvia, Collins, Mia, Dahl, Göran, Elmqvist, David, Grimster, Neil P., Hendrickx, Ramon, Johansson, Johan R., Kettle, Jason G., Lepistö, Matti, Rhedin, Magdalena, Smailagic, Amir, Su, Qibin, Wennberg, Tiiu, Wu, Allan, Österlund, Torben, Naessens, Thomas, Mitra, Suman
Published in Journal of medicinal chemistry (12.10.2023)

Get full text

Journal Article

AZD0284, a Potent, Selective, and Orally Bioavailable Inverse Agonist of Retinoic Acid Receptor-Related Orphan Receptor C2

AZD0284, a Potent, Selective, and Orally Bioavailable Inverse Agonist of Retinoic Acid Receptor-Related Orphan Receptor C2

by Narjes, Frank, Llinas, Antonio, von Berg, Stefan, Jirholt, Johan, Lever, Sarah, Pehrson, Rikard, Collins, Mia, Malmberg, Anna, Svanberg, Petter, Xue, Yafeng, Olsson, Roine I, Malmberg, Jesper, Hughes, Glyn, Hossain, Nafizal, Grindebacke, Hanna, Leffler, Agnes, Krutrök, Nina, Bäck, Elisabeth, Ramnegård, Marie, Lepistö, Matti, Thunberg, Linda, Aagaard, Anna, McPheat, Jane, Hansson, Eva L, Chen, Rongfeng, Xiong, Yao, Hansson, Thomas G
Published in Journal of medicinal chemistry (23.09.2021)

Get full text

Journal Article

Potent and Orally Bioavailable Inverse Agonists of RORγt Resulting from Structure-Based Design

Potent and Orally Bioavailable Inverse Agonists of RORγt Resulting from Structure-Based Design

by Narjes, Frank, Xue, Yafeng, von Berg, Stefan, Malmberg, Jesper, Llinas, Antonio, Olsson, Roine I, Jirholt, Johan, Grindebacke, Hanna, Leffler, Agnes, Hossain, Nafizal, Lepistö, Matti, Thunberg, Linda, Leek, Hanna, Aagaard, Anna, McPheat, Jane, Hansson, Eva L, Bäck, Elisabeth, Tångefjord, Stefan, Chen, Rongfeng, Xiong, Yao, Hongbin, Ge, Hansson, Thomas G
Published in Journal of medicinal chemistry (13.09.2018)

Get full text

Journal Article

Selective Nonsteroidal Glucocorticoid Receptor Modulators for the Inhaled Treatment of Pulmonary Diseases

Selective Nonsteroidal Glucocorticoid Receptor Modulators for the Inhaled Treatment of Pulmonary Diseases

by Hemmerling, Martin, Nilsson, Stinabritt, Edman, Karl, Eirefelt, Stefan, Russell, Wayne, Hendrickx, Ramon, Johnsson, Eskil, Kärrman Mårdh, Carina, Berger, Markus, Rehwinkel, Hartmut, Abrahamsson, Anna, Dahmén, Jan, Eriksson, Anders R, Gabos, Balint, Henriksson, Krister, Hossain, Nafizal, Ivanova, Svetlana, Jansson, Anne-Helene, Jensen, Tina J, Jerre, Anders, Johansson, Henrik, Klingstedt, Tomas, Lepistö, Matti, Lindsjö, Martin, Mile, Irene, Nikitidis, Grigorios, Steele, John, Tehler, Ulrika, Wissler, Lisa, Hansson, Thomas
Published in Journal of medicinal chemistry (26.10.2017)

Get full text

Journal Article

The effect of AZD9567 vs. prednisolone on glycaemic control in patients with type 2 diabetes mellitus: Results from a phase 2a clinical trial

The effect of AZD9567 vs. prednisolone on glycaemic control in patients with type 2 diabetes mellitus: Results from a phase 2a clinical trial

by Ambery, Philip, Zajac, Grzegorz, Almquist, Joachim, Prothon, Susanne, Astbury, Carol, Brown, Mary N., Nemes, Szilard, Nsabimana, Joselyne, Edman, Karl, Öberg, Lisa, Lepistö, Matti, Edenro, Goran, Dillmann, Inken, Mitra, Suman, Belfield, Graham, Keen, Christina, Heise, Tim
Published in British journal of clinical pharmacology (01.08.2024)

Get full text

Journal Article

Saccharin Aza BioisosteresSynthesis and Preclinical Property Comparisons

Saccharin Aza BioisosteresSynthesis and Preclinical Property Comparisons

by Chen, Yantao, Aurell, Carl-Johan, Pettersen, Anna, Lewis, Richard J, Hayes, Martin A, Lepistö, Matti, Jonson, Anna C, Leek, Hanna, Thunberg, Linda
Published in ACS medicinal chemistry letters (08.06.2017)

Get full text

Journal Article

Discovery of Potent and Orally Bioavailable Inverse Agonists of the Retinoic Acid Receptor-Related Orphan Receptor C2

Discovery of Potent and Orally Bioavailable Inverse Agonists of the Retinoic Acid Receptor-Related Orphan Receptor C2

by von Berg, Stefan, Xue, Yafeng, Collins, Mia, Llinas, Antonio, Olsson, Roine I, Halvarsson, Torbjörn, Lindskog, Maria, Malmberg, Jesper, Jirholt, Johan, Krutrök, Nina, Ramnegård, Marie, Brännström, Marie, Lundqvist, Anders, Lepistö, Matti, Aagaard, Anna, McPheat, Jane, Hansson, Eva L, Chen, Rongfeng, Xiong, Yao, Hansson, Thomas G, Narjes, Frank
Published in ACS medicinal chemistry letters (13.06.2019)

Get full text

Journal Article

Discovery of indazole ethers as novel, potent, non-steroidal glucocorticoid receptor modulators

Discovery of indazole ethers as novel, potent, non-steroidal glucocorticoid receptor modulators

by Hemmerling, Martin, Edman, Karl, Lepistö, Matti, Eriksson, Anders, Ivanova, Svetlana, Dahmén, Jan, Rehwinkel, Hartmut, Berger, Markus, Hendrickx, Ramon, Dearman, Matthew, Jensen, Tina Jellesmark, Wissler, Lisa, Hansson, Thomas
Published in Bioorganic & medicinal chemistry letters (01.12.2016)

Get full text

Journal Article

HTS followed by NMR based counterscreening. Discovery and optimization of pyrimidones as reversible and competitive inhibitors of xanthine oxidase

HTS followed by NMR based counterscreening. Discovery and optimization of pyrimidones as reversible and competitive inhibitors of xanthine oxidase

by Evenas, Johan, Edfeldt, Fredrik, Lepisto, Matti, Svitacheva, Naila, Synnergren, Anna, Lundquist, Britta, Granse, Mia, Ronnholm, Anna, Varga, Mikael, Wright, John, Wei, Min, Yue, Sherrie, Wang, Junfeng, Li, Chong, Li, Xuan, Chen, Gang, Liao, Yong, Lv, Gang, Tjornebo, Ann, Narjes, Frank
Published in Bioorganic & medicinal chemistry letters (01.03.2014)

Get full text

Journal Article

The discovery of potent and selective non-steroidal glucocorticoid receptor modulators, suitable for inhalation

The discovery of potent and selective non-steroidal glucocorticoid receptor modulators, suitable for inhalation

by Edman, Karl, Ahlgren, Ragnhild, Bengtsson, Malena, Bladh, Håkan, Bäckström, Stefan, Dahmén, Jan, Henriksson, Krister, Hillertz, Per, Hulikal, Vijakumar, Jerre, Anders, Kinchin, Liz, Kåse, Charlotte, Lepistö, Matti, Mile, Irene, Nilsson, Stinabritt, Smailagic, Amir, Taylor, John, Tjörnebo, Ann, Wissler, Lisa, Hansson, Thomas
Published in Bioorganic & medicinal chemistry letters (01.06.2014)

Get full text

Journal Article

The deubiquitinase USP7 uses a distinct ubiquitin-like domain to deubiquitinate NF-ĸB subunits

The deubiquitinase USP7 uses a distinct ubiquitin-like domain to deubiquitinate NF-ĸB subunits

by Mitxitorena, Izaskun, Somma, Domenico, Mitchell, Jennifer P., Lepistö, Matti, Tyrchan, Christian, Smith, Emma L., Kiely, Patrick A., Walden, Helen, Keeshan, Karen, Carmody, Ruaidhrí J.
Published in The Journal of biological chemistry (14.08.2020)

Get full text

Journal Article

Backbone 1 H, 13 C, and 15 N resonance assignments of the ligand binding domain of the human wildtype glucocorticoid receptor and the F602S mutant variant

Backbone 1 H, 13 C, and 15 N resonance assignments of the ligand binding domain of the human wildtype glucocorticoid receptor and the F602S mutant variant

by Köhler, Christian, Carlström, Göran, Tångefjord, Stefan, Papavoine, Tineke, Lepistö, Matti, Edman, Karl, Akke, Mikael
Published in Biomolecular NMR assignments (01.10.2018)

Get full text

Journal Article

JAK1 SELECTIVE INHIBITORS

JAK1 SELECTIVE INHIBITORS

by SU, Qibin, KAWATKAR, Sameer Pralhad, JOHANSSON, Johan R, BERGGREN, Anna Ingrid Kristina, KETTLE, Jason Grant, NILSSON, KARL MAGNUS, ÅSTRAND, Annika Birgitta Margareta, LEPISTÖ, Matti Juhani
Year of Publication 27.06.2024

Get full text

Patent

JAK1 selective inhibitors

JAK1 selective inhibitors

by Åstrand, Annika Birgitta Margareta, Nilsson, Karl Magnus, Su, Qibin, Kettle, Jason Grant, Lepistö, Matti Juhani, Berggren, Anna Ingrid Kristina, Johansson, Johan R, Kawatkar, Sameer Pralhad
Year of Publication 13.02.2024

Get full text

Patent

1
2
3
4
5
6
7
8
9
10
11
Next
[18]