Comprehensive Transcriptome Profiling of Cryptic CBFA2T3-GLIS2 Fusion-Positive AML Defines Novel Therapeutic Options: A COG and TARGET Pediatric AML Study
Smith, Jenny L, Ries, Rhonda E, Hylkema, Tiffany, Alonzo, Todd A, Gerbing, Robert B, Santaguida, Marianne T, Eidenschink Brodersen, Lisa, Pardo, Laura, Cummings, Carrie L, Loeb, Keith R, Le, Quy, Imren, Suzan, Leonti, Amanda R, Gamis, Alan S, Aplenc, Richard, Kolb, E Anders, Farrar, Jason E, Triche, Jr, Timothy J, Nguyen, Cu, Meerzaman, Daoud, Loken, Michael R, Oehler, Vivian G, Bolouri, Hamid, Meshinchi, Soheil
Published in Clinical cancer research (01.02.2020)
Published in Clinical cancer research (01.02.2020)
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Integrated stem cell signature and cytomolecular risk determination in pediatric acute myeloid leukemia
Huang, Benjamin J., Smith, Jenny L., Farrar, Jason E., Wang, Yi-Cheng, Umeda, Masayuki, Ries, Rhonda E., Leonti, Amanda R., Crowgey, Erin, Furlan, Scott N., Tarlock, Katherine, Armendariz, Marcos, Liu, Yanling, Shaw, Timothy I., Wei, Lisa, Gerbing, Robert B., Cooper, Todd M., Gamis, Alan S., Aplenc, Richard, Kolb, E. Anders, Rubnitz, Jeffrey, Ma, Jing, Klco, Jeffery M., Ma, Xiaotu, Alonzo, Todd A., Triche, Timothy, Meshinchi, Soheil
Published in Nature communications (19.09.2022)
Published in Nature communications (19.09.2022)
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Journal Article
Myeloid lineage enhancers drive oncogene synergy in CEBPA/CSF3R mutant acute myeloid leukemia
Braun, Theodore P., Okhovat, Mariam, Coblentz, Cody, Carratt, Sarah A., Foley, Amy, Schonrock, Zachary, Curtiss, Brittany M., Nevonen, Kimberly, Davis, Brett, Garcia, Brianna, LaTocha, Dorian, Weeder, Benjamin R., Grzadkowski, Michal R., Estabrook, Joey C., Manning, Hannah G., Watanabe-Smith, Kevin, Jeng, Sophia, Smith, Jenny L., Leonti, Amanda R., Ries, Rhonda E., McWeeney, Shannon, Di Genua, Cristina, Drissen, Roy, Nerlov, Claus, Meshinchi, Soheil, Carbone, Lucia, Druker, Brian J., Maxson, Julia E.
Published in Nature communications (29.11.2019)
Published in Nature communications (29.11.2019)
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Author Correction: Myeloid lineage enhancers drive oncogene synergy in CEBPA/CSF3R mutant acute myeloid leukemia
Braun, Theodore P., Okhovat, Mariam, Coblentz, Cody, Carratt, Sarah A., Foley, Amy, Schonrock, Zachary, Curtiss, Brittany M., Nevonen, Kimberly, Davis, Brett, Garcia, Brianna, LaTocha, Dorian, Weeder, Benjamin R., Grzadkowski, Michal R., Estabrook, Joey C., Manning, Hannah G., Watanabe-Smith, Kevin, Jeng, Sophia, Smith, Jenny L., Leonti, Amanda R., Ries, Rhonda E., McWeeney, Shannon, Di Genua, Cristina, Drissen, Roy, Nerlov, Claus, Meshinchi, Soheil, Carbone, Lucia, Druker, Brian J., Maxson, Julia E.
Published in Nature communications (16.06.2022)
Published in Nature communications (16.06.2022)
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Valosin‐containing protein (VCP/p97) is prognostically unfavorable in pediatric AML, and negatively correlates with unfolded protein response proteins IRE1 and GRP78: A report from the Children's Oncology Group
Hoff, Fieke W., Qiu, Yihua, Brown, Brandon D., Gerbing, Robert B., Leonti, Amanda R., Ries, Rhonda E., Gamis, Alan S., Aplenc, Richard, Kolb, Edward Anders, Alonzo, Todd A., Meshinchi, Soheil, Jenkins, Gaye N., Horton, Terzah M., Kornblau, Steven M.
Published in Proteomics. Clinical applications (01.11.2023)
Published in Proteomics. Clinical applications (01.11.2023)
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Comprehensive molecular and clinical characterization of NUP98 fusions in pediatric acute myeloid leukemia
Bertrums, Eline J M, Smith, Jenny L, Harmon, Lauren, Ries, Rhonda E, Wang, Yi-Cheng J, Alonzo, Todd A, Menssen, Andrew J, Chisholm, Karen M, Leonti, Amanda R, Tarlock, Katherine, Ostronoff, Fabiana, Pogosova-Agadjanyan, Era L, Kaspers, Gertjan J L, Hasle, Henrik, Dworzak, Michael, Walter, Christiane, Muhlegger, Nora, Morerio, Cristina, Pardo, Laura, Hirsch, Betsy, Raimondi, Susana, Cooper, Todd M, Aplenc, Richard, Gamis, Alan S, Kolb, Edward A, Farrar, Jason E, Stirewalt, Derek, Ma, Xiaotu, Shaw, Tim I, Furlan, Scott N, Brodersen, Lisa Eidenschink, Loken, Michael R, Van den Heuvel-Eibrink, Marry M, Zwaan, C Michel, Triche, Timothy J, Goemans, Bianca F, Meshinchi, Soheil
Published in Haematologica (Roma) (01.08.2023)
Published in Haematologica (Roma) (01.08.2023)
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Heat shock factor 1 (HSF1-pSer326) predicts response to bortezomib-containing chemotherapy in pediatric AML: a COG report
Hoff, Fieke W., van Dijk, Anneke D., Qiu, Yihua, Ruvolo, Peter P., Gerbing, Robert B., Leonti, Amanda R., Jenkins, Gaye N., Gamis, Alan S., Aplenc, Richard, Kolb, E. Anders, Alonzo, Todd A., Meshinchi, Soheil, de Bont, Eveline S.J.M., Bruggeman, Sophia W.M., Kornblau, Steven M., Horton, Terzah M.
Published in Blood (25.02.2021)
Published in Blood (25.02.2021)
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Therapeutic targeting of PRAME with mTCRCAR T cells in acute myeloid leukemia
Kirkey, Danielle C., Loeb, Anisha M., Castro, Sommer, McKay, Cyd Nourigat, Perkins, LaKeisha, Pardo, Laura, Leonti, Amanda R., Tang, Thao T., Loken, Michael R., Brodersen, Lisa Eidenschink, Loeb, Keith R., Scheinberg, David A., Le, Quy, Meshinchi, Soheil
Published in Blood advances (11.04.2023)
Published in Blood advances (11.04.2023)
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Integrated Genomic Analysis Identifies UBTF Tandem Duplications as a Recurrent Lesion in Pediatric Acute Myeloid Leukemia
Umeda, Masayuki, Ma, Jing, Huang, Benjamin J, Hagiwara, Kohei, Westover, Tamara, Abdelhamed, Sherif, Barajas, Juan M, Thomas, Melvin E, Walsh, Michael P, Song, Guangchun, Tian, Liqing, Liu, Yanling, Chen, Xiaolong, Kolekar, Pandurang, Tran, Quang, Foy, Scott G, Maciaszek, Jamie L, Kleist, Andrew B, Leonti, Amanda R, Ju, Bengsheng, Easton, John, Wu, Huiyun, Valentine, Virginia, Valentine, Marcus B, Liu, Yen-Chun, Ries, Rhonda E, Smith, Jenny L, Parganas, Evan, Iacobucci, Ilaria, Hiltenbrand, Ryan, Miller, Jonathan, Myers, Jason R, Rampersaud, Evadnie, Rahbarinia, Delaram, Rusch, Michael, Wu, Gang, Inaba, Hiroto, Wang, Yi-Cheng, Alonzo, Todd A, Downing, James R, Mullighan, Charles G, Pounds, Stanley, Babu, M Madan, Zhang, Jinghui, Rubnitz, Jeffrey E, Meshinchi, Soheil, Ma, Xiaotu, Klco, Jeffery M
Published in Blood cancer discovery (05.05.2022)
Published in Blood cancer discovery (05.05.2022)
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Chromatin Profiles Are Prognostic of Clinical Response to Bortezomib-Containing Chemotherapy in Pediatric Acute Myeloid Leukemia: Results from the COG AAML1031 Trial
van Dijk, Anneke D, Hoff, Fieke W, Qiu, Yihua, Hubner, Stefan E, Go, Robin L, Ruvolo, Vivian R, Leonti, Amanda R, Gerbing, Robert B, Gamis, Alan S, Aplenc, Richard, Kolb, Edward A, Alonzo, Todd A, Meshinchi, Soheil, de Bont, Eveline S J M, Horton, Terzah M, Kornblau, Steven M
Published in Cancers (09.04.2024)
Published in Cancers (09.04.2024)
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Mesothelin is a novel cell surface disease marker and potential therapeutic target in acute myeloid leukemia
Kaeding, Allison J., Barwe, Sonali P., Gopalakrishnapillai, Anilkumar, Ries, Rhonda E., Alonzo, Todd A., Gerbing, Robert B., Correnti, Colin, Loken, Michael R., Broderson, Lisa Eidenschink, Pardo, Laura, Le, Quy H., Tang, Thao, Leonti, Amanda R., Smith, Jenny L., Chou, Cassie K., Xu, Min, Triche, Tim, Kornblau, Steven M., Kolb, E. Anders, Tarlock, Katherine, Meshinchi, Soheil
Published in Blood advances (11.05.2021)
Published in Blood advances (11.05.2021)
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Journal Article
CBFB-MYH11 fusion transcripts distinguish acute myeloid leukemias with distinct molecular landscapes and outcomes
Huang, Benjamin J., Smith, Jenny L., Wang, Yi-Cheng, Taghizadeh, Kassra, Leonti, Amanda R., Ries, Rhonda E., Liu, Yanling, Kolekar, Pandurang, Tarlock, Katherine, Gerbing, Robert, Crowgey, Erin, Furlan, Scott N., Shaw, Timothy I., Hagiwara, Kohei, Wei, Lisa, Cooper, Todd M., Gamis, Alan S., Aplenc, Richard, Kolb, E. Anders, Farrar, Jason E., Triche, Timothy, Alonzo, Todd A., Ma, Xiaotu, Meshinchi, Soheil
Published in Blood advances (14.12.2021)
Published in Blood advances (14.12.2021)
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Journal Article
Identifying a Relapse Signature in CBFB-MYH11 Acute Myeloid Leukemia
Peplinski, Jack H, Wallace, Logan K, Ries, Rhonda E, Huang, Benjamin J, Leonti, Amanda R, Kirkey, Danielle C, Ma, Xiaotu, Furlan, Scott N, Meshinchi, Soheil
Published in Blood (02.11.2023)
Published in Blood (02.11.2023)
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Target-Informed Repurposing of Immunotherapies in AML - a Transcriptome Based Approach for Identifying Immediately Available Therapeutics
Leonti, Amanda R., Manselle, Makia, Smith, Jenny L., Ries, Rhonda E., Kolb, Anders E., Meshinchi, Soheil
Published in Blood (05.11.2020)
Published in Blood (05.11.2020)
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Journal Article
Functional Consequence and Therapeutic Targeting of Cryptic ALK Fusions (ALK fus) in Monosomy7 AML
Manselle, Makia K., Hylkema, Tiffany A., Leonti, Amanda R., Ries, Rhonda E., Le, Quy, Furlan, Scott N, Meshinchi, Soheil
Published in Blood (23.11.2021)
Published in Blood (23.11.2021)
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Transcriptome Profiling of Pediatric Myeloproliferative Neoplasms Demonstrates Dysregulation of Platelet-Relevant Genes and Enrichment of Inflammatory and JAK2 Mediated Complement Pathways
Kucine, Nicole, Leonti, Amanda R., Krishnan, Aishwarya, Ries, Rhonda E., Levine, Ross L., Meshinchi, Soheil
Published in Blood (13.11.2019)
Published in Blood (13.11.2019)
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Immunotherapeutic Targeting of TSLPR with Chimeric Antigen Receptor T Cells in AML
Call, Lindsey F, Castro, Sommer, Tang, Thao T., Nourigat-Mckay, Cynthia, Perkins, LaKeisha, Pardo, Laura, Leonti, Amanda R., Meshinchi, Soheil, Le, Quy
Published in Blood (23.11.2021)
Published in Blood (23.11.2021)
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Therapeutic Targeting of Mesothelin with Chimeric Antigen Receptor Natural Killer Cell Therapy in Acute Myeloid Leukemia
Tang, Thao T., Call, Lindsey F, Castro, Sommer, Nourigat-Mckay, Cynthia, Perkins, LaKeisha, Pardo, Laura, Leonti, Amanda R., Meshinchi, Soheil, Le, Quy
Published in Blood (23.11.2021)
Published in Blood (23.11.2021)
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Journal Article
The Transcriptomic Landscape of NUP98-Rearranged Pediatric Acute Myeloid Leukemia
Smith, Jenny L., Bertrums, Eline J.M., Ries, Rhonda E., Ostronoff, Fabiana, Leonti, Amanda R., Furlan, Scott N., Goemans, Bianca F., Meshinchi, Soheil
Published in Blood (05.11.2020)
Published in Blood (05.11.2020)
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Therapeutic Targeting of Mesothelin in Acute Myeloid Leukemia with Chimeric Antigen Receptor T Cell Therapy
Le, Quy, Castro, Sommer, Tang, Thao T., Loeb, Anisha, Leonti, Amanda R., Pardo, Laura, Loken, Michael R., Correnti, Colin, Meshinchi, Soheil
Published in Blood (05.11.2020)
Published in Blood (05.11.2020)
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