TRIF Licenses Caspase-11-Dependent NLRP3 Inflammasome Activation by Gram-Negative Bacteria
Rathinam, Vijay A.K., Vanaja, Sivapriya Kailasan, Waggoner, Lisa, Sokolovska, Anna, Becker, Christine, Stuart, Lynda M., Leong, John M., Fitzgerald, Katherine A.
Published in Cell (03.08.2012)
Published in Cell (03.08.2012)
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Journal Article
Prevalence and pattern of lumbar magnetic resonance imaging changes in a population study of one thousand forty-three individuals
Cheung, Kenneth M C, Karppinen, Jaro, Chan, Danny, Ho, Daniel W H, Song, You-Qiang, Sham, Pak, Cheah, Kathryn S E, Leong, John C Y, Luk, Keith D K
Published in Spine (Philadelphia, Pa. 1976) (20.04.2009)
Published in Spine (Philadelphia, Pa. 1976) (20.04.2009)
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Journal Article
Prophage induction, but not production of phage particles, is required for lethal disease in a microbiome-replete murine model of enterohemorrhagic E. coli infection
Balasubramanian, Sowmya, Osburne, Marcia S, BrinJones, Haley, Tai, Albert K, Leong, John M
Published in PLoS pathogens (01.01.2019)
Published in PLoS pathogens (01.01.2019)
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Journal Article
Macrophage LC3-associated phagocytosis is an immune defense against Streptococcus pneumoniae that diminishes with host aging
Inomata, Megumi, Xu, Shuying, Chandra, Pallavi, Meydani, Simin N., Takemura, Genzou, Philips, Jennifer A., Leong, John M.
Published in Proceedings of the National Academy of Sciences - PNAS (29.12.2020)
Published in Proceedings of the National Academy of Sciences - PNAS (29.12.2020)
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Journal Article
Intimate host attachment: enteropathogenic and enterohaemorrhagic Escherichia coli
Lai, YuShuan, Rosenshine, Ilan, Leong, John M., Frankel, Gad
Published in Cellular microbiology (01.11.2013)
Published in Cellular microbiology (01.11.2013)
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Journal Article
Extracellular Adenosine Protects against Streptococcus pneumoniae Lung Infection by Regulating Pulmonary Neutrophil Recruitment
Bou Ghanem, Elsa N, Clark, Stacie, Roggensack, Sara E, McIver, Sally R, Alcaide, Pilar, Haydon, Philip G, Leong, John M
Published in PLoS pathogens (01.08.2015)
Published in PLoS pathogens (01.08.2015)
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VlsE, the nexus for antigenic variation of the Lyme disease spirochete, also mediates early bacterial attachment to the host microvasculature under shear force
Tan, Xi, Lin, Yi-Pin, Pereira, Michael J, Castellanos, Mildred, Hahn, Beth L, Anderson, Phillip, Coburn, Jenifer, Leong, John M, Chaconas, George
Published in PLoS pathogens (01.05.2022)
Published in PLoS pathogens (01.05.2022)
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Whole genome sequencing of human Borrelia burgdorferi isolates reveals linked blocks of accessory genome elements located on plasmids and associated with human dissemination
Lemieux, Jacob E, Huang, Weihua, Hill, Nathan, Cerar, Tjasa, Freimark, Lisa, Hernandez, Sergio, Luban, Matteo, Maraspin, Vera, Bogovič, Petra, Ogrinc, Katarina, Ruzič-Sabljič, Eva, Lapierre, Pascal, Lasek-Nesselquist, Erica, Singh, Navjot, Iyer, Radha, Liveris, Dionysios, Reed, Kurt D, Leong, John M, Branda, John A, Steere, Allen C, Wormser, Gary P, Strle, Franc, Sabeti, Pardis C, Schwartz, Ira, Strle, Klemen
Published in PLoS pathogens (01.08.2023)
Published in PLoS pathogens (01.08.2023)
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Journal Article
Lumbar disc degeneration is linked to a carbohydrate sulfotransferase 3 variant
Song, You-Qiang, Karasugi, Tatsuki, Cheung, Kenneth M C, Chiba, Kazuhiro, Ho, Daniel W H, Miyake, Atsushi, Kao, Patrick Y P, Sze, Kit Ling, Yee, Anita, Takahashi, Atsushi, Kawaguchi, Yoshiharu, Mikami, Yasuo, Matsumoto, Morio, Togawa, Daisuke, Kanayama, Masahiro, Shi, Dongquan, Dai, Jin, Jiang, Qing, Wu, Chengai, Tian, Wei, Wang, Na, Leong, John C Y, Luk, Keith D K, Yip, Shea-ping, Cherny, Stacey S, Wang, Junwen, Mundlos, Stefan, Kelempisioti, Anthi, Eskola, Pasi J, Männikkö, Minna, Mäkelä, Pirkka, Karppinen, Jaro, Järvelin, Marjo-Riitta, O'Reilly, Paul F, Kubo, Michiaki, Kimura, Tomoatsu, Kubo, Toshikazu, Toyama, Yoshiaki, Mizuta, Hiroshi, Cheah, Kathryn S E, Tsunoda, Tatsuhiko, Sham, Pak-Chung, Ikegawa, Shiro, Chan, Danny
Published in The Journal of clinical investigation (01.11.2013)
Published in The Journal of clinical investigation (01.11.2013)
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Journal Article
The Yin and Yang of Pneumolysin During Pneumococcal Infection
Pereira, Joana M, Xu, Shuying, Leong, John M, Sousa, Sandra
Published in Frontiers in immunology (22.04.2022)
Published in Frontiers in immunology (22.04.2022)
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Journal Article
Editorial overview of Pearls Microbiome Series: E pluribus unum
Hogan, Deborah A, Heitman, Joseph, Jabra-Rizk, Mary Ann, Knoll, Laura J, Leong, John M, Silverman, Neal
Published in PLoS pathogens (31.08.2021)
Published in PLoS pathogens (31.08.2021)
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Journal Article
Bacterial RNA:DNA hybrids are activators of the NLRP3 inflammasome
Vanaja, Sivapriya Kailasan, Rathinam, Vijay A. K., Atianand, Maninjay K., Kalantari, Parisa, Skehan, Brian, Fitzgerald, Katherine A., Leong, John M.
Published in Proceedings of the National Academy of Sciences - PNAS (27.05.2014)
Published in Proceedings of the National Academy of Sciences - PNAS (27.05.2014)
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Journal Article
Pore-forming activity of S. pneumoniae pneumolysin disrupts the paracellular localization of the epithelial adherens junction protein E-cadherin
Xu, Shuying, Mo, Devons, Rizvi, Fatima Z., Rosa, Juan P., Ruiz, Jorge, Tan, Shumin, Tweten, Rodney K., Leong, John M., Adams, Walter
Published in Infection and immunity (14.09.2023)
Published in Infection and immunity (14.09.2023)
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Journal Article
Engineered Escherichia coli for the in situ secretion of therapeutic nanobodies in the gut
Lynch, Jason P., González-Prieto, Coral, Reeves, Analise Z., Bae, Sena, Powale, Urmila, Godbole, Neha P., Tremblay, Jacqueline M., Schmidt, Florian I., Ploegh, Hidde L., Kansra, Vikram, Glickman, Jonathan N., Leong, John M., Shoemaker, Charles B., Garrett, Wendy S., Lesser, Cammie F.
Published in Cell host & microbe (12.04.2023)
Published in Cell host & microbe (12.04.2023)
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