Somatic mutation landscapes at single-molecule resolution
Abascal, Federico, Harvey, Luke M R, Mitchell, Emily, Lawson, Andrew R J, Lensing, Stefanie V, Ellis, Peter, Russell, Andrew J C, Alcantara, Raul E, Baez-Ortega, Adrian, Wang, Yichen, Kwa, Eugene Jing, Lee-Six, Henry, Cagan, Alex, Coorens, Tim H H, Chapman, Michael Spencer, Olafsson, Sigurgeir, Leonard, Steven, Jones, David, Machado, Heather E, Davies, Megan, Øbro, Nina F, Mahubani, Krishnaa T, Allinson, Kieren, Gerstung, Moritz, Saeb-Parsy, Kourosh, Kent, David G, Laurenti, Elisa, Stratton, Michael R, Rahbari, Raheleh, Campbell, Peter J, Osborne, Robert J, Martincorena, Iñigo
Published in Nature (London) (20.05.2021)
Published in Nature (London) (20.05.2021)
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Inherited MUTYH mutations cause elevated somatic mutation rates and distinctive mutational signatures in normal human cells
Robinson, Philip S, Thomas, Laura E, Abascal, Federico, Jung, Hyunchul, Harvey, Luke M R, West, Hannah D, Olafsson, Sigurgeir, Lee, Bernard C H, Coorens, Tim H H, Lee-Six, Henry, Butlin, Laura, Lander, Nicola, Truscott, Rebekah, Sanders, Mathijs A, Lensing, Stefanie V, Buczacki, Simon J A, Ten Hoopen, Rogier, Coleman, Nicholas, Brunton-Sim, Roxanne, Rushbrook, Simon, Saeb-Parsy, Kourosh, Lalloo, Fiona, Campbell, Peter J, Martincorena, Iñigo, Sampson, Julian R, Stratton, Michael R
Published in Nature communications (08.07.2022)
Published in Nature communications (08.07.2022)
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Journal Article
G-quadruplex structures mark human regulatory chromatin
Hänsel-Hertsch, Robert, Beraldi, Dario, Lensing, Stefanie V, Marsico, Giovanni, Zyner, Katherine, Parry, Aled, Di Antonio, Marco, Pike, Jeremy, Kimura, Hiroshi, Narita, Masashi, Tannahill, David, Balasubramanian, Shankar
Published in Nature genetics (01.10.2016)
Published in Nature genetics (01.10.2016)
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Journal Article
DSBCapture: in situ capture and sequencing of DNA breaks
Lensing, Stefanie V, Marsico, Giovanni, Hänsel-Hertsch, Robert, Lam, Enid Y, Tannahill, David, Balasubramanian, Shankar
Published in Nature methods (01.10.2016)
Published in Nature methods (01.10.2016)
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Journal Article
Patterns of within-host genetic diversity in SARS-CoV-2
Tonkin-Hill, Gerry, Martincorena, Inigo, Amato, Roberto, Lawson, Andrew R J, Gerstung, Moritz, Johnston, Ian, Jackson, David K, Park, Naomi, Lensing, Stefanie V, Quail, Michael A, Gonçalves, Sónia, Ariani, Cristina, Spencer Chapman, Michael, Hamilton, William L, Meredith, Luke W, Hall, Grant, Jahun, Aminu S, Chaudhry, Yasmin, Hosmillo, Myra, Pinckert, Malte L, Georgana, Iliana, Yakovleva, Anna, Caller, Laura G, Caddy, Sarah L, Feltwell, Theresa, Khokhar, Fahad A, Houldcroft, Charlotte J, Curran, Martin D, Parmar, Surendra, Alderton, Alex, Nelson, Rachel, Harrison, Ewan M, Sillitoe, John, Bentley, Stephen D, Barrett, Jeffrey C, Torok, M Estee, Goodfellow, Ian G, Langford, Cordelia, Kwiatkowski, Dominic
Published in eLife (13.08.2021)
Published in eLife (13.08.2021)
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SARS-CoV-2 evolution during treatment of chronic infection
Kemp, Steven A, Collier, Dami A, Datir, Rawlings P, Ferreira, Isabella A T M, Gayed, Salma, Jahun, Aminu, Hosmillo, Myra, Rees-Spear, Chloe, Mlcochova, Petra, Lumb, Ines Ushiro, Roberts, David J, Chandra, Anita, Temperton, Nigel, Sharrocks, Katherine, Blane, Elizabeth, Modis, Yorgo, Leigh, Kendra E, Briggs, John A G, van Gils, Marit J, Smith, Kenneth G C, Bradley, John R, Smith, Chris, Doffinger, Rainer, Ceron-Gutierrez, Lourdes, Barcenas-Morales, Gabriela, Pollock, David D, Goldstein, Richard A, Smielewska, Anna, Skittrall, Jordan P, Gouliouris, Theodore, Goodfellow, Ian G, Gkrania-Klotsas, Effrossyni, Illingworth, Christopher J R, McCoy, Laura E, Gupta, Ravindra K
Published in Nature (London) (08.04.2021)
Published in Nature (London) (08.04.2021)
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SARS-CoV-2 Omicron is an immune escape variant with an altered cell entry pathway
Willett, Brian J, Grove, Joe, MacLean, Oscar A, Wilkie, Craig, De Lorenzo, Giuditta, Furnon, Wilhelm, Cantoni, Diego, Scott, Sam, Logan, Nicola, Ashraf, Shirin, Manali, Maria, Szemiel, Agnieszka, Cowton, Vanessa, Vink, Elen, Harvey, William T, Davis, Chris, Asamaphan, Patawee, Smollett, Katherine, Tong, Lily, Orton, Richard, Hughes, Joseph, Holland, Poppy, Silva, Vanessa, Pascall, David J, Puxty, Kathryn, da Silva Filipe, Ana, Yebra, Gonzalo, Shaaban, Sharif, Holden, Matthew T G, Pinto, Rute Maria, Gunson, Rory, Templeton, Kate, Murcia, Pablo R, Patel, Arvind H, Klenerman, Paul, Dunachie, Susanna, Haughney, John, Robertson, David L, Palmarini, Massimo, Ray, Surajit, Thomson, Emma C
Published in Nature microbiology (01.08.2022)
Published in Nature microbiology (01.08.2022)
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Genomic reconstruction of the SARS-CoV-2 epidemic in England
Vöhringer, Harald S, Sanderson, Theo, Sinnott, Matthew, De Maio, Nicola, Nguyen, Thuy, Goater, Richard, Schwach, Frank, Harrison, Ian, Hellewell, Joel, Ariani, Cristina V, Gonçalves, Sonia, Jackson, David K, Johnston, Ian, Jung, Alexander W, Saint, Callum, Sillitoe, John, Suciu, Maria, Goldman, Nick, Panovska-Griffiths, Jasmina, Birney, Ewan, Volz, Erik, Funk, Sebastian, Kwiatkowski, Dominic, Chand, Meera, Martincorena, Inigo, Barrett, Jeffrey C, Gerstung, Moritz
Published in Nature (London) (16.12.2021)
Published in Nature (London) (16.12.2021)
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Changes in symptomatology, reinfection, and transmissibility associated with the SARS-CoV-2 variant B.1.1.7: an ecological study
Graham, Mark S, Sudre, Carole H, Ash, Amy, Moore, Nathan, Golubchik, Tanya, Spellman, Karla, Fuller, William, Nebbia, Gaia, Taylor, Ben EW, Willingham, Iona, Sheriff, Nicola, Moore, Christopher, Debebe, Johnny, Wilson, Harry D, Davis, Thomas, Pybus, Oliver G, Raghwani, Jayna, Heaney, Judith, Smith, Darren L, Jorgensen, David, Siveroni, Igor, Boyd, Olivia, Smollett, Katherine L, Quick, Joshua, Halstead, Fenella, Sivaprakasam, Venkat, Illingworth, Chris J, Jesudason, Natasha G, Johnson, Natasha, Robertson, David L, Taha, Yusri, Blacow, Rachel, McHugh, Martin P, Dewar, Rebecca, Stanley, Rachael, Peto, Timothy, Elliott, Scott, Pearson, Clare, Osman, Husam, Robinson, Esther, Mbisa, Tamyo, Bibby, David, Hubb, Jonathan, Lee, David, Manesis, Nikos, Bishop, Chloe, Shaaban, Sharif, Morgan, Mari, Cronin, Michelle, Corden, Sally, Page, Andrew J, Baker, David J, Meadows, Lizzie, Molnar, Zoltan, Acheson, Erwan, Masoli, Jane AH, Ellard, Sian, Irish-Tavares, Dianne, Dent, Hannah, Partridge, David G, Raza, Mohammad, Evans, Cariad, Essex, Sarah, Silveira, Siona, Jones, Katie, Percival, Benita, Mirza, Jeremy, Ashcroft, Fiona, Bucca, Giselda, Forrest, Sally, Maes, Mailis, Hadjirin, Nazreen F, Balcazar, Carlos E, Hill, Verity, Michell, Stephen L, Manley, Robin, Sambles, Christine M, Hiscox, Julian A, Gregory, Richard, Wierzbicki, Claudia, Lindsey, Benjamin B, Groves, Danielle C, Cheng, Jeffrey K.J., Brown, Paul E, Wilson, Rebekah E, McClure, Patrick C, Alderton, Alex, Amato, Roberto, Beale, Mathew A, Bellis, Katherine L, Harrison, Ewan M, Jackson, David K, Kwiatkowski, Dominic, Livett, Rich, McGuigan, Samantha, Prestwood, Liam, Shirley, Lesley, Tonkin-Hill, Gerry, Bronner, Iraad F, Tovar-Corona, Jaime M
Published in The Lancet. Public health (01.05.2021)
Published in The Lancet. Public health (01.05.2021)
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COVID-19 due to the B.1.617.2 (Delta) variant compared to B.1.1.7 (Alpha) variant of SARS-CoV-2: a prospective observational cohort study
Kläser, Kerstin, Molteni, Erika, Graham, Mark, Canas, Liane S, Österdahl, Marc F, Antonelli, Michela, Chen, Liyuan, Deng, Jie, Murray, Benjamin, Kerfoot, Eric, Wolf, Jonathan, May, Anna, Fox, Ben, Capdevila, Joan, Modat, Marc, Hammers, Alexander, Spector, Tim D, Steves, Claire J, Sudre, Carole H, Ourselin, Sebastien, Duncan, Emma L
Published in Scientific reports (28.06.2022)
Published in Scientific reports (28.06.2022)
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Genomic epidemiology of SARS-CoV-2 in a UK university identifies dynamics of transmission
Aggarwal, Dinesh, Warne, Ben, Jahun, Aminu S, Hamilton, William L, Fieldman, Thomas, du Plessis, Louis, Hill, Verity, Blane, Beth, Watkins, Emmeline, Wright, Elizabeth, Hall, Grant, Ludden, Catherine, Myers, Richard, Hosmillo, Myra, Chaudhry, Yasmin, Pinckert, Malte L, Georgana, Iliana, Izuagbe, Rhys, Leek, Danielle, Nsonwu, Olisaeloka, Hughes, Gareth J, Packer, Simon, Page, Andrew J, Metaxaki, Marina, Fuller, Stewart, Weale, Gillian, Holgate, Jon, Brown, Christopher A, Howes, Rob, McFarlane, Duncan, Dougan, Gordon, Pybus, Oliver G, Angelis, Daniela De, Maxwell, Patrick H, Peacock, Sharon J, Weekes, Michael P, Illingworth, Chris, Harrison, Ewan M, Matheson, Nicholas J, Goodfellow, Ian G
Published in Nature communications (08.02.2022)
Published in Nature communications (08.02.2022)
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Journal Article
DSBCapture: in situ capture and direct sequencing of dsDNA breaks
Lensing, Stefanie V., Marsico, Giovanni, Hänsel-Hertsch, Robert, Lam, Enid Y., Tannahill, David, Balasubramanian, Shankar
Published in Nature methods (15.08.2016)
Published in Nature methods (15.08.2016)
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Genomic assessment of quarantine measures to prevent SARS-CoV-2 importation and transmission
Aggarwal, Dinesh, Page, Andrew J, Schaefer, Ulf, Savva, George M, Myers, Richard, Volz, Erik, Ellaby, Nicholas, Platt, Steven, Groves, Natalie, Gallagher, Eileen, Tumelty, Niamh M, Le Viet, Thanh, Hughes, Gareth J, Chen, Cong, Turner, Charlie, Logan, Sophie, Harrison, Abbie, Peacock, Sharon J, Chand, Meera, Harrison, Ewan M
Published in Nature communications (23.02.2022)
Published in Nature communications (23.02.2022)
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Genomic epidemiology of SARS-CoV-2 in a university outbreak setting and implications for public health planning
Nickbakhsh, Sema, Hughes, Joseph, Christofidis, Nicolaos, Griffiths, Emily, Shaaban, Sharif, Enright, Jessica, Smollett, Katherine, Nomikou, Kyriaki, Palmalux, Natasha, Tong, Lily, Carmichael, Stephen, Sreenu, Vattipally B, Orton, Richard, Goldstein, Emily J, Tomb, Rachael M, Templeton, Kate, Gunson, Rory N, da Silva Filipe, Ana, Milosevic, Catriona, Thomson, Emma, Robertson, David L, Holden, Matthew T G, Illingworth, Christopher J R, Smith-Palmer, Alison
Published in Scientific reports (19.07.2022)
Published in Scientific reports (19.07.2022)
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Journal Article
Publisher Correction: SARS-CoV-2 Omicron is an immune escape variant with an altered cell entry pathway
Willett, Brian J, Grove, Joe, MacLean, Oscar A, Wilkie, Craig, De Lorenzo, Giuditta, Furnon, Wilhelm, Cantoni, Diego, Scott, Sam, Logan, Nicola, Ashraf, Shirin, Manali, Maria, Szemiel, Agnieszka, Cowton, Vanessa, Vink, Elen, Harvey, William T, Davis, Chris, Asamaphan, Patawee, Smollett, Katherine, Tong, Lily, Orton, Richard, Hughes, Joseph, Holland, Poppy, Silva, Vanessa, Pascall, David J, Puxty, Kathryn, da Silva Filipe, Ana, Yebra, Gonzalo, Shaaban, Sharif, Holden, Matthew T G, Pinto, Rute Maria, Gunson, Rory, Templeton, Kate, Murcia, Pablo R, Patel, Arvind H, Klenerman, Paul, Dunachie, Susanna, Haughney, John, Robertson, David L, Palmarini, Massimo, Ray, Surajit, Thomson, Emma C
Published in Nature microbiology (01.10.2022)
Published in Nature microbiology (01.10.2022)
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Journal Article
Patterns of within-host genetic diversity in SARS-CoV-2
Tonkin-Hill, Gerry, Martincorena, Inigo, Amato, Roberto, Lawson, Andrew R J, Gerstung, Moritz, Johnston, Ian, Jackson, David K, Park, Naomi R, Lensing, Stefanie V, Quail, Michael A, Gonçalves, Sónia, Ariani, Cristina, Michael Spencer Chapman, Hamilton, William L, Meredith, Luke W, Hall, Grant, Jahun, Aminu S, Chaudhry, Yasmin, Hosmillo, Myra, Pinckert, Malte L, Georgana, Iliana, Yakovleva, Anna, Caller, Laura G, Caddy, Sarah L, Feltwell, Theresa, Khokhar, Fahad A, Houldcroft, Charlotte J, Curran, Martin D, Parmar, Surendra, The Covid-19 Genomics Uk (Cog-Uk) Consortium, Alderton, Alex, Nelson, Rachel, Harrison, Ewan, Sillitoe, John, Bentley, Stephen D, Barrett, Jeffrey C, M Estee Torok, Goodfellow, Ian G, Langford, Cordelia, Kwiatkowski, Dominic, Wellcome Sanger Institute Covid-19 Surveillance Team
Published in bioRxiv (25.12.2020)
Published in bioRxiv (25.12.2020)
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