Modulating glycosphingolipid metabolism and autophagy improves outcomes in pre-clinical models of myeloma bone disease
Leng, Houfu, Zhang, Hanlin, Li, Linsen, Zhang, Shuhao, Wang, Yanping, Chavda, Selina J., Galas-Filipowicz, Daria, Lou, Hantao, Ersek, Adel, Morris, Emma V., Sezgin, Erdinc, Lee, Yi-Hsuan, Li, Yunsen, Lechuga-Vieco, Ana Victoria, Tian, Mei, Mi, Jian-Qing, Yong, Kwee, Zhong, Qing, Edwards, Claire M., Simon, Anna Katharina, Horwood, Nicole J.
Published in Nature communications (22.12.2022)
Published in Nature communications (22.12.2022)
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Journal Article
A Mouse Model with a Frameshift Mutation in the Nuclear Factor I/X (NFIX) Gene Has Phenotypic Features of Marshall‐Smith Syndrome
Kooblall, Kreepa G., Stevenson, Mark, Stewart, Michelle, Harris, Lachlan, Zalucki, Oressia, Dewhurst, Hannah, Butterfield, Natalie, Leng, Houfu, Hough, Tertius A., Ma, Da, Siow, Bernard, Potter, Paul, Cox, Roger D., Brown, Stephen D.M., Horwood, Nicole, Wright, Benjamin, Lockstone, Helen, Buck, David, Vincent, Tonia L., Hannan, Fadil M., Bassett, J.H. Duncan, Williams, Graham R., Lines, Kate E., Piper, Michael, Wells, Sara, Teboul, Lydia, Hennekam, Raoul C., Thakker, Rajesh V.
Published in JBMR plus (01.06.2023)
Published in JBMR plus (01.06.2023)
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Proteostasis in T cell aging
Gressler, A. Elisabeth, Leng, Houfu, Zinecker, Heidi, Simon, Anna Katharina
Published in Seminars in immunology (01.11.2023)
Published in Seminars in immunology (01.11.2023)
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Journal Article
Altering Glycosphingolipid Composition to Improve Multiple Myeloma Bone Complication
Leng, Houfu, Ersek, Adel, Morris, Emma, Molina, Beatriz Gamez, Edwards, Claire M., Horwood, Nicole
Published in Blood (29.11.2018)
Published in Blood (29.11.2018)
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Journal Article
The glycosphingolipid inhibitor eliglustat inhibits autophagy in osteoclasts to increase bone mass and reduce myeloma bone disease
Leng, Houfu, Zhang, Hanlin, Li, Linsen, Zhang, Shuhao, Wang, Yanping, Ersek, Adel, Morris, Emma, Sezgin, Erdinc, Lee, Yi-Hsuan, Li, Yunsen, Mi, Jianqing, Zhong, Qing, Edwards, Claire, Simon, Anna Katharina, Horwood, Nicole J
Published in bioRxiv (06.02.2021)
Published in bioRxiv (06.02.2021)
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