Search Results - "Lena Ripa" :: K.UTB vyhledávací portál | TBU Library Retrieval Portal

HDAC6 inhibitor ACY-1083 shows lung epithelial protective features in COPD

HDAC6 inhibitor ACY-1083 shows lung epithelial protective features in COPD

by Horndahl, Jenny, Svärd, Rebecka, Berntsson, Pia, Wingren, Cecilia, Li, Jingjing, Abdillahi, Suado M, Ghosh, Baishakhi, Capodanno, Erin, Chan, Justin, Ripa, Lena, Åstrand, Annika, Sidhaye, Venkataramana K, Collins, Mia
Published in PloS one (12.10.2022)

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Journal Article

Theoretical Studies of Chemical Reactivity of Metabolically Activated Forms of Aromatic Amines toward DNA

Theoretical Studies of Chemical Reactivity of Metabolically Activated Forms of Aromatic Amines toward DNA

by Shamovsky, Igor, Ripa, Lena, Blomberg, Niklas, Eriksson, Leif A, Hansen, Peter, Mee, Christine, Tyrchan, Christian, O'Donovan, Mike, Sjö, Peter
Published in Chemical research in toxicology (15.10.2012)

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Journal Article

Theoretical Studies of the Mechanism of Carbamoylation of Nucleobases by Isocyanates

Theoretical Studies of the Mechanism of Carbamoylation of Nucleobases by Isocyanates

by Liljenberg, Magnus, Ripa, Lena, Shamovsky, Igor
Published in Chemical research in toxicology (16.11.2020)

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Journal Article

Mechanism-Based Insights into Removing the Mutagenicity of Aromatic Amines by Small Structural Alterations

Mechanism-Based Insights into Removing the Mutagenicity of Aromatic Amines by Small Structural Alterations

by Shamovsky, Igor, Ripa, Lena, Narjes, Frank, Bonn, Britta, Schiesser, Stefan, Terstiege, Ina, Tyrchan, Christian
Published in Journal of medicinal chemistry (24.06.2021)

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Journal Article

Selective and Bioavailable HDAC6 2‑(Difluoromethyl)-1,3,4-oxadiazole Substrate Inhibitors and Modeling of Their Bioactivation Mechanism

Selective and Bioavailable HDAC6 2‑(Difluoromethyl)-1,3,4-oxadiazole Substrate Inhibitors and Modeling of Their Bioactivation Mechanism

by Ripa, Lena, Sandmark, Jenny, Hughes, Glyn, Shamovsky, Igor, Gunnarsson, Anders, Johansson, Julia, Llinas, Antonio, Collins, Mia, Jung, Bomi, Novén, Anna, Pemberton, Nils, Mogemark, Mickael, Xiong, Yao, Li, Qing, Tångefjord, Stefan, Ek, Margareta, Åstrand, Annika
Published in Journal of medicinal chemistry (26.10.2023)

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A Phenotypic Screening Approach Using Human Treg Cells Identified Regulators of Forkhead Box p3 Expression

A Phenotypic Screening Approach Using Human Treg Cells Identified Regulators of Forkhead Box p3 Expression

by Ding, Mei, Brengdahl, Johan, Lindqvist, Madelene, Gehrmann, Ulf, Ericson, Elke, von Berg, Stefan, Ripa, Lena, Malhotra, Rajneesh
Published in ACS chemical biology (15.03.2019)

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Journal Article

Theoretical studies of the second step of the nitric oxide synthase reaction: Electron tunneling prevents uncoupling

Theoretical studies of the second step of the nitric oxide synthase reaction: Electron tunneling prevents uncoupling

by Shamovsky, Igor, Belfield, Graham, Lewis, Richard, Narjes, Frank, Ripa, Lena, Tyrchan, Christian, Öberg, Lisa, Sjö, Peter
Published in Journal of inorganic biochemistry (01.04.2018)

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Journal Article

Discovery of a Novel Oral Glucocorticoid Receptor Modulator (AZD9567) with Improved Side Effect Profile

by Ripa, Lena, Edman, Karl, Dearman, Matthew, Edenro, Goran, Hendrickx, Ramon, Ullah, Victoria, Chang, Hui-Fang, Lepistö, Matti, Chapman, Dave, Geschwindner, Stefan, Wissler, Lisa, Svanberg, Petter, Lawitz, Karolina, Malmberg, Jesper, Nikitidis, Antonios, Olsson, Roine I, Bird, James, Llinas, Antoni, Hegelund-Myrbäck, Tove, Berger, Markus, Thorne, Philip, Harrison, Richard, Köhler, Christian, Drmota, Tomas
Published in Journal of medicinal chemistry (08.03.2018)

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Theoretical Studies of the Mechanism of N‑Hydroxylation of Primary Aromatic Amines by Cytochrome P450 1A2: Radicaloid or Anionic?

Theoretical Studies of the Mechanism of N‑Hydroxylation of Primary Aromatic Amines by Cytochrome P450 1A2: Radicaloid or Anionic?

by Ripa, Lena, Mee, Christine, Sjö, Peter, Shamovsky, Igor
Published in Chemical research in toxicology (17.02.2014)

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Journal Article

Explanation for Main Features of Structure–Genotoxicity Relationships of Aromatic Amines by Theoretical Studies of Their Activation Pathways in CYP1A2

Explanation for Main Features of Structure–Genotoxicity Relationships of Aromatic Amines by Theoretical Studies of Their Activation Pathways in CYP1A2

by Shamovsky, Igor, Ripa, Lena, Börjesson, Lena, Mee, Christine, Nordén, Bo, Hansen, Peter, Hasselgren, Catrin, O’Donovan, Mike, Sjö, Peter
Published in Journal of the American Chemical Society (12.10.2011)

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Journal Article

Fragment-Based Discovery of Novel Allosteric MEK1 Binders

Fragment-Based Discovery of Novel Allosteric MEK1 Binders

by Di Fruscia, Paolo, Edfeldt, Fredrik, Shamovsky, Igor, Collie, Gavin W, Aagaard, Anna, Barlind, Louise, Börjesson, Ulf, Hansson, Eva L, Lewis, Richard J, Nilsson, Magnus K, Öster, Linda, Pemberton, Josefine, Ripa, Lena, Storer, R. Ian, Käck, Helena
Published in ACS medicinal chemistry letters (11.02.2021)

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Journal Article

Discovery of the Oral Leukotriene C4 Synthase Inhibitor (1S,2S)‑2-({5-[(5-Chloro-2,4-difluorophenyl)(2-fluoro-2-methylpropyl)amino]-3-methoxypyrazin-2-yl}carbonyl)cyclopropanecarboxylic Acid (AZD9898) as a New Treatment for Asthma

Discovery of the Oral Leukotriene C4 Synthase Inhibitor (1S,2S)‑2-({5-[(5-Chloro-2,4-difluorophenyl)(2-fluoro-2-methylpropyl)amino]-3-methoxypyrazin-2-yl}carbonyl)cyclopropanecarboxylic Acid (AZD9898) as a New Treatment for Asthma

by Munck af Rosenschöld, Magnus, Johannesson, Petra, Nikitidis, Antonios, Tyrchan, Christian, Chang, Hui-Fang, Rönn, Robert, Chapman, Dave, Ullah, Victoria, Nikitidis, Grigorios, Glader, Pernilla, Käck, Helena, Bonn, Britta, Wågberg, Fredrik, Björkstrand, Eva, Andersson, Ulf, Swedin, Linda, Rohman, Mattias, Andreasson, Theresa, Bergström, Eva Lamm, Jiang, Fanyi, Zhou, Xiao-Hong, Lundqvist, Anders J, Malmberg, Anna, Ek, Margareta, Gordon, Euan, Pettersen, Anna, Ripa, Lena, Davis, Andrew M
Published in Journal of medicinal chemistry (12.09.2019)

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Journal Article

HDAC6 inhibitor ACY-1083 shows lung epithelial protective features in COPD

HDAC6 inhibitor ACY-1083 shows lung epithelial protective features in COPD

by Jenny Horndahl, Rebecka Svärd, Pia Berntsson, Cecilia Wingren, Jingjing Li, Suado M Abdillahi, Baishakhi Ghosh, Erin Capodanno, Justin Chan, Lena Ripa, Annika Åstrand, Venkataramana K Sidhaye, Mia Collins
Published in PloS one (01.01.2022)

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Journal Article

Advances in the design of new types of inhaled medicines

Advances in the design of new types of inhaled medicines

by Czechtizky, Werngard, Su, Wu, Ripa, Lena, Schiesser, Stefan, Höijer, Andreas, Cox, Rhona J
Published in Progress in medicinal chemistry (01.01.2022)

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Journal Article

Increasing Selectivity of CC Chemokine Receptor 8 Antagonists by Engineering Nondesolvation Related Interactions with the Intended and Off-Target Binding Sites

Increasing Selectivity of CC Chemokine Receptor 8 Antagonists by Engineering Nondesolvation Related Interactions with the Intended and Off-Target Binding Sites

by Shamovsky, Igor, de Graaf, Chris, Alderin, Lisa, Bengtsson, Malena, Bladh, Håkan, Börjesson, Lena, Connolly, Stephen, Dyke, Hazel J, van den Heuvel, Marco, Johansson, Henrik, Josefsson, Bo-Göran, Kristoffersson, Anna, Linnanen, Tero, Lisius, Annea, Männikkö, Roope, Nordén, Bo, Price, Steve, Ripa, Lena, Rognan, Didier, Rosendahl, Alexander, Skrinjar, Marco, Urbahns, Klaus
Published in Journal of medicinal chemistry (10.12.2009)

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Journal Article

Intramolecular Enantioselective Palladium-Catalyzed Heck Arylation of Cyclic Enamides

Intramolecular Enantioselective Palladium-Catalyzed Heck Arylation of Cyclic Enamides

by Ripa, Lena, Hallberg, Anders
Published in Journal of organic chemistry (07.02.1997)

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Journal Article

Synthesis of Two Conformationally Constrained Analogues of the Minor Tobacco Alkaloid Anabasine

Synthesis of Two Conformationally Constrained Analogues of the Minor Tobacco Alkaloid Anabasine

by Lindström, Stefan, Ripa, Lena, Hallberg, Anders
Published in Organic letters (27.07.2000)

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Journal Article

Controlled Double-Bond Migration in Palladium-Catalyzed Intramolecular Arylation of Enamidines

Controlled Double-Bond Migration in Palladium-Catalyzed Intramolecular Arylation of Enamidines

by Ripa, Lena, Hallberg, Anders
Published in Journal of organic chemistry (04.10.1996)

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Journal Article

Aryl Radical Endo Cyclization of Enamidines. Selective Preparation of Trans and Cis Fused Octahydrobenzo[f]quinolines

Aryl Radical Endo Cyclization of Enamidines. Selective Preparation of Trans and Cis Fused Octahydrobenzo[f]quinolines

by Ripa, Lena, Hallberg, Anders
Published in Journal of organic chemistry (09.01.1998)

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Journal Article

3,4-DIAMINO-6-CHLORPYRAZINE-2-CARBOXAMIDE DERIVATIVES FOR THE TREATMENT OF ENAC MEDIATED DISEASES

3,4-DIAMINO-6-CHLORPYRAZINE-2-CARBOXAMIDE DERIVATIVES FOR THE TREATMENT OF ENAC MEDIATED DISEASES

by KRISTOFFERSSON, ANNA, RIPA, LENA ELISABETH, BERGLUND, SUSANNE ELISABETH, HOSSAIN, NAFIZAL, CONNOLLY, STEPHEN, HEMMERLING, MARTIN, LUNDKVIST, JOHAN RUNE MICHAEL, SHAMOVSKY, IGOR, NIKITIDIS, GRIGORIOS
Year of Publication 07.03.2023

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