Side‐Chain Interactions in d/l Peptide Nanotubes: Studies by Crystallography, NMR Spectroscopy and Molecular Dynamics
Silk, Mitchell R., Price, Jason R., Mohanty, Biswaranjan, Leiros, Hanna‐Kirsti S., Lund, Bjarte A., Thompson, Philip E., Chalmers, David K.
Published in Chemistry : a European journal (19.10.2021)
Published in Chemistry : a European journal (19.10.2021)
Get full text
Journal Article
Structural and biochemical characterization of VIM‐26 shows that Leu224 has implications for the substrate specificity of VIM metallo‐β‐lactamases
Leiros, Hanna‐Kirsti S, Edvardsen, Kine Susann Waade, Bjerga, Gro Elin Kjæreng, Samuelsen, Ørjan
Published in The FEBS journal (01.03.2015)
Published in The FEBS journal (01.03.2015)
Get full text
Journal Article
The biological assembly of OXA‐48 reveals a dimer interface with high charge complementarity and very high affinity
Lund, Bjarte Aarmo, Thomassen, Ane Molden, Nesheim, Birgit Helene Berg, Carlsen, Trine Josefine Olsen, Isaksson, Johan, Christopeit, Tony, Leiros, Hanna‐Kirsti S.
Published in The FEBS journal (01.11.2018)
Published in The FEBS journal (01.11.2018)
Get full text
Journal Article
Exploring the role of L209 residue in the active site of NDM-1 a metallo-β-lactamase
Marcoccia, Francesca, Leiros, Hanna-Kirsti S, Aschi, Massimiliano, Amicosante, Gianfranco, Perilli, Mariagrazia
Published in PloS one (01.01.2018)
Published in PloS one (01.01.2018)
Get full text
Journal Article
Bacteriophage origin of some minimal ATP-dependent DNA ligases: a new structure from Burkholderia pseudomallei with striking similarity to Chlorella virus ligase
Pan, Jolyn, Lian, Kjersti, Sarre, Aili, Leiros, Hanna-Kirsti S., Williamson, Adele
Published in Scientific reports (21.09.2021)
Published in Scientific reports (21.09.2021)
Get full text
Journal Article
Crystal Structure of the Mobile Metallo-β-Lactamase AIM-1 from Pseudomonas aeruginosa: Insights into Antibiotic Binding and the Role of Gln157
Leiros, Hanna-Kirsti S, Borra, Pardha S, Brandsdal, Bjørn Olav, Edvardsen, Kine Susann Waade, Spencer, James, Walsh, Timothy R, Samuelsen, Orjan
Published in Antimicrobial Agents and Chemotherapy (01.08.2012)
Published in Antimicrobial Agents and Chemotherapy (01.08.2012)
Get full text
Journal Article
The structure of the metallo-β-lactamase VIM-2 in complex with a triazolylthioacetamide inhibitor
Christopeit, Tony, Yang, Ke-Wu, Yang, Shao-Kang, Leiros, Hanna-Kirsti S.
Published in Acta crystallographica. Section F, Structural biology and crystallization communications (01.11.2016)
Published in Acta crystallographica. Section F, Structural biology and crystallization communications (01.11.2016)
Get full text
Journal Article
Discovery of a Specific Inhibitor of Pyomelanin Synthesis in Legionella pneumophila
Aubi, Oscar, Flydal, Marte I, Zheng, Huaixin, Skjærven, Lars, Rekand, Illimar, Leiros, Hanna-Kirsti S, Haug, Bengt Erik, Cianciotto, Nicholas P, Martinez, Aurora, Underhaug, Jarl
Published in Journal of medicinal chemistry (12.11.2015)
Published in Journal of medicinal chemistry (12.11.2015)
Get full text
Journal Article
Structure, activity and thermostability investigations of OXA‐163, OXA‐181 and OXA‐245 using biochemical analysis, crystal structures and differential scanning calorimetry analysis
Lund, Bjarte Aarmo, Thomassen, Ane Molden, Carlsen, Trine Josefine Olsen, Leiros, Hanna-Kirsti S.
Published in Acta crystallographica. Section F, Structural biology and crystallization communications (01.10.2017)
Published in Acta crystallographica. Section F, Structural biology and crystallization communications (01.10.2017)
Get full text
Journal Article
Crystal Structures of Pseudomonas aeruginosa GIM-1: Active-Site Plasticity in Metallo-β-Lactamases
BORRA, Pardha Saradhi, SAMUELSEN, Orjan, SPENCER, James, WALSH, Timothy R, LORENTZEN, Marit Sjo, LEIROS, Hanna-Kirsti S
Published in Antimicrobial Agents and Chemotherapy (01.02.2013)
Published in Antimicrobial Agents and Chemotherapy (01.02.2013)
Get full text
Journal Article
Fluorinated captopril analogues inhibit metallo-β-lactamases and facilitate structure determination of NDM-1 binding pose
Kondratieva, Alexandra, Palica, Katarzyna, Frøhlich, Christopher, Hovd, Rebekka Rolfsnes, Leiros, Hanna-Kirsti S., Erdelyi, Mate, Bayer, Annette
Published in European journal of medicinal chemistry (15.02.2024)
Published in European journal of medicinal chemistry (15.02.2024)
Get full text
Journal Article
Discovery of Novel Inhibitor Scaffolds against the Metallo-β-lactamase VIM‑2 by Surface Plasmon Resonance (SPR) Based Fragment Screening
Christopeit, Tony, Carlsen, Trine Josefine O, Helland, Ronny, Leiros, Hanna-Kirsti S
Published in Journal of medicinal chemistry (12.11.2015)
Published in Journal of medicinal chemistry (12.11.2015)
Get full text
Journal Article
Structure of Phenylalanine Hydroxylase from Colwellia psychrerythraea 34H, a Monomeric Cold Active Enzyme with Local Flexibility around the Active Site and High Overall Stability
Leiros, Hanna-Kirsti S., Pey, Angel L., Innselset, Marte, Moe, Elin, Leiros, Ingar, Steen, Ida Helene, Martinez, Aurora
Published in The Journal of biological chemistry (27.07.2007)
Published in The Journal of biological chemistry (27.07.2007)
Get full text
Journal Article
Metallo-β-lactamase inhibitors by bioisosteric replacement: Preparation, activity and binding
Skagseth, Susann, Akhter, Sundus, Paulsen, Marianne H., Muhammad, Zeeshan, Lauksund, Silje, Samuelsen, Ørjan, Leiros, Hanna-Kirsti S., Bayer, Annette
Published in European journal of medicinal chemistry (28.07.2017)
Published in European journal of medicinal chemistry (28.07.2017)
Get full text
Journal Article
Discovery of a novel covalent non-β-lactam inhibitor of the metallo-β-lactamase NDM-1
Christopeit, Tony, Albert, Anastasia, Leiros, Hanna-Kirsti S.
Published in Bioorganic & medicinal chemistry (01.07.2016)
Published in Bioorganic & medicinal chemistry (01.07.2016)
Get full text
Journal Article