Guanosine enhances glutamate uptake and oxidation, preventing oxidative stress in mouse hippocampal slices submitted to high glutamate levels
Nonose, Y., Pieper, L.Z., da Silva, J.S., Longoni, A., Apel, R.V., Meira-Martins, L.A., Grings, M., Leipnitz, G., Souza, D.O., de Assis, A.M.
Published in Brain research (01.12.2020)
Published in Brain research (01.12.2020)
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Evidences that maternal swimming exercise improves antioxidant defenses and induces mitochondrial biogenesis in the brain of young Wistar rats
Marcelino, T.B, Longoni, A, Kudo, K.Y, Stone, V, RECH, A, de Assis, A.M, Scherer, E.B.S, da Cunha, M.J, Wyse, A.T.S, Pettenuzzo, L.F, Leipnitz, G, Matté, C
Published in Neuroscience (29.08.2013)
Published in Neuroscience (29.08.2013)
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Reactive nitrogen species mediate oxidative stress and astrogliosis provoked by in vivo administration of phytanic acid in cerebellum of adolescent rats: A potential contributing pathomechanism of cerebellar injury in peroxisomal disorders
Borges, C.G, Canani, C.R, Fernandes, C.G, Zanatta, Â, Seminotti, B, Ribeiro, C.A.J, Leipnitz, G, Vargas, C.R, Wajner, M
Published in Neuroscience (24.09.2015)
Published in Neuroscience (24.09.2015)
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Toxic synergism between quinolinic acid and organic acids accumulating in glutaric acidemia type I and in disorders of propionate metabolism in rat brain synaptosomes: Relevance for metabolic acidemias
Colín-González, A.L, Paz-Loyola, A.L, Serratos, I, Seminotti, B, Ribeiro, C.A.J, Leipnitz, G, Souza, D.O, Wajner, M, Santamaría, A
Published in Neuroscience (12.11.2015)
Published in Neuroscience (12.11.2015)
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The effect of WIN 55,212-2 suggests a cannabinoid-sensitive component in the early toxicity induced by organic acids accumulating in glutaric acidemia type I and in related disorders of propionate metabolism in rat brain synaptosomes
Colín-González, A.L, Paz-Loyola, A.L, Serratos, I.N, Seminotti, B, Ribeiro, C.A.J, Leipnitz, G, Souza, D.O, Wajner, M, Santamaría, A
Published in Neuroscience (03.12.2015)
Published in Neuroscience (03.12.2015)
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Disruption of redox homeostasis and histopathological alterations caused by in vivo intrastriatal administration of D-2-hydroxyglutaric acid to young rats
da Rosa, M.S, Seminotti, B, Amaral, A.U, Parmeggiani, B, de Oliveira, F.H, Leipnitz, G, Wajner, M
Published in Neuroscience (26.09.2014)
Published in Neuroscience (26.09.2014)
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Redox homeostasis is compromised in vivo by the metabolites accumulating in 3-hydroxy-3-methylglutaryl-CoA lyase deficiency in rat cerebral cortex and liver
da Rosa, M. S., Seminotti, B., Amaral, A. U., Fernandes, C. G., Gasparotto, J., Moreira, J. C. F., Gelain, D. P., Wajner, M., Leipnitz, G.
Published in Free radical research (01.12.2013)
Published in Free radical research (01.12.2013)
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Disruption of redox homeostasis and brain damage caused in vivo by methylmalonic acid and ammonia in cerebral cortex and striatum of developing rats
Viegas, C. M., Zanatta, Â., Grings, M., Hickmann, F. H., Monteiro, W. O., Soares, L. E., Sitta, Â., Leipnitz, G., de Oliveira, F. H., Wajner, M.
Published in Free radical research (01.06.2014)
Published in Free radical research (01.06.2014)
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Journal Article
Promotion of oxidative stress by 3‐hydroxyglutaric acid in rat striatum
Latini, A., Scussiato, K., Leipnitz, G., Dutra‐Filho, C. S., Wajner, M.
Published in Journal of inherited metabolic disease (01.01.2005)
Published in Journal of inherited metabolic disease (01.01.2005)
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3-Hydroxyglutaric acid moderately impairs energy metabolism in brain of young rats
Latini, A., Rodriguez, M., Borba Rosa, R., Scussiato, K., Leipnitz, G., Reis de Assis, D., da Costa Ferreira, G., Funchal, C., Jacques-Silva, M.C., Buzin, L., Giugliani, R., Cassina, A., Radi, R., Wajner, M.
Published in Neuroscience (2005)
Published in Neuroscience (2005)
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Inhibition of energy metabolism by 2‐methylacetoacetate and 2‐methyl‐3‐hydroxybutyrate in cerebral cortex of developing rats
Rosa, R. B., Schuck, P. F., Assis, D. R. de, Latini, A., Dalcin, K. B., Ribeiro, C. A. J., Ferreira, G. da C., Maria, R. C., Leipnitz, G., Perry, M. L. S., Filho, C. S. Dutra, Wyse, A. T. S., Wannmacher, C. M. D., Wajner, M.
Published in Journal of inherited metabolic disease (2005)
Published in Journal of inherited metabolic disease (2005)
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D-2-Hydroxyglutaric acid inhibits creatine kinase activity from cardiac and skeletal muscle of young rats
Da Silva, C. G., Bueno, A. R. F., Schuck, P. F., Leipnitz, G., Ribeiro, C. A. J., Wannmacher, C. M. D., Wyse, A. T. S., Wajner, M.
Published in European journal of clinical investigation (01.10.2003)
Published in European journal of clinical investigation (01.10.2003)
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Half-life of single-chain urokinase-type plasminogen activator (scu-PA) and two-chain urokinase-type plasminogen activator (tcu-PA) in patients with acute myocardial infarction
Köhler, M., Sen, S., Miyashita, C., Hermes, R., Pindur, G., Heiden, M., Berg, G., Mörsdorf, S., Leipnitz, G., Zeppezauer, M., Schieffer, H., Wenzel, E., Schönberger, A., Hollemeyer, K.
Published in Thrombosis research (01.04.1991)
Published in Thrombosis research (01.04.1991)
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Creatine administration prevents Na super(+),K super(+)-ATPase inhibition induced by intracerebroventricular administration of isovaleric acid in cerebral cortex of young rats
Ribeiro, CAJ, Leipnitz, G, Amaral, A U, de Bortoli, G, Seminotti, B, Wajner, M
Published in Brain research (25.03.2009)
Published in Brain research (25.03.2009)
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D-Serine induces lipid and protein oxidative damage and decreases glutathione levels in brain cortex of rats
da Silva, Lucila de Bortoli, Leipnitz, Guilhian, Seminotti, Bianca, Fernandes, Carolina G, Beskow, Ana Paula, Amaral, Alexandre U, Wajner, Moacir
Published in Brain research (23.02.2009)
Published in Brain research (23.02.2009)
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Journal Article
Induction of oxidative stress by L-2-hydroxyglutaric acid in rat brain
Latini, Alexandra, Scussiato, Karina, Borba Rosa, Rafael, Leipnitz, Guilhian, Llesuy, Susana, Belló-Klein, Adriane, Dutra-Filho, Carlos Severo, Wajner, Moacir
Published in Journal of neuroscience research (01.10.2003)
Published in Journal of neuroscience research (01.10.2003)
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