Cutting Edge: Severe SARS-CoV-2 Infection in Humans Is Defined by a Shift in the Serum Lipidome, Resulting in Dysregulation of Eicosanoid Immune Mediators
Schwarz, Benjamin, Sharma, Lokesh, Roberts, Lydia, Peng, Xiaohua, Bermejo, Santos, Leighton, Ian, Casanovas-Massana, Arnau, Minasyan, Maksym, Farhadian, Shelli, Ko, Albert I, Dela Cruz, Charles S, Bosio, Catharine M
Published in The Journal of immunology (1950) (15.01.2021)
Published in The Journal of immunology (1950) (15.01.2021)
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High-Fat High-Sugar Diet-Induced Changes in the Lipid Metabolism Are Associated with Mildly Increased COVID-19 Severity and Delayed Recovery in the Syrian Hamster
Port, Julia R, Adney, Danielle R, Schwarz, Benjamin, Schulz, Jonathan E, Sturdevant, Daniel E, Smith, Brian J, Avanzato, Victoria A, Holbrook, Myndi G, Purushotham, Jyothi N, Stromberg, Kaitlin A, Leighton, Ian, Bosio, Catharine M, Shaia, Carl, Munster, Vincent J
Published in Viruses (14.12.2021)
Published in Viruses (14.12.2021)
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Clinical benefit of remdesivir in rhesus macaques infected with SARS-CoV-2
Williamson, Brandi N., Feldmann, Friederike, Schwarz, Benjamin, Meade-White, Kimberly, Porter, Danielle P., Schulz, Jonathan, van Doremalen, Neeltje, Leighton, Ian, Yinda, Claude Kwe, Pérez-Pérez, Lizzette, Okumura, Atsushi, Lovaglio, Jamie, Hanley, Patrick W., Saturday, Greg, Bosio, Catharine M., Anzick, Sarah, Barbian, Kent, Cihlar, Tomas, Martens, Craig, Scott, Dana P., Munster, Vincent J., de Wit, Emmie
Published in Nature (London) (10.09.2020)
Published in Nature (London) (10.09.2020)
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Itaconate indirectly influences expansion of effector T cells following vaccination with Francisella tularensis live vaccine strain
Roberts, Lydia M., Leighton, Ian, Schwarz, Benjamin, Wehrly, Tara D., Evans, Tyler J., Bosio, Catharine M.
Published in Cellular immunology (01.03.2022)
Published in Cellular immunology (01.03.2022)
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Circulating T Cells Are Not Sufficient for Protective Immunity against Virulent Francisella tularensis
Roberts, Lydia M, Wehrly, Tara D, Leighton, Ian, Hanley, Patrick, Lovaglio, Jamie, Smith, Brian J, Bosio, Catharine M
Published in The Journal of immunology (1950) (01.03.2022)
Published in The Journal of immunology (1950) (01.03.2022)
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Grainyhead-like-2 confers NK-sensitivity through interactions with epigenetic modifiers
MacFawn, Ian, Wilson, Hannah, Selth, Luke A., Leighton, Ian, Serebriiskii, Ilya, Bleackley, R. Christopher, Elzamzamy, Osama, Farris, Joshua, Pifer, Phillip M., Richer, Jennifer, Frisch, Steven M.
Published in Molecular immunology (01.01.2019)
Published in Molecular immunology (01.01.2019)
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Severe SARS-CoV-2 infection in humans is defined by a shift in the serum lipidome resulting in dysregulation of eicosanoid immune mediators1
Schwarz, Benjamin, Sharma, Lokesh, Roberts, Lydia, Peng, Xiaohua, Bermejo, Santos, Leighton, Ian, Massana, Arnau Casanovas, Minasyan, Maksym, Farhadian, Shelli, Ko, Albert I., Cruz, Charles S. Dela, Bosio, Catharine M.
Published in The Journal of immunology (1950) (04.12.2020)
Published in The Journal of immunology (1950) (04.12.2020)
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Comparison of the specificities of p70 S6 kinase and MAPKAP kinase-1 identifies a relatively specific substrate for p70 S6 kinase: the N-terminal kinase domain of MAPKAP kinase-1 is essential for peptide phosphorylation
Leighton, Ian A., Dalby, Kevin N., Barry Caudwell, F., Cohen, Patricia T.W., Cohen, Philip
Published in FEBS letters (20.11.1995)
Published in FEBS letters (20.11.1995)
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Budget Impact Analysis of a New-Generation Recombinant Factor VIII from a Human Cell Line (Nuwiq) for the Treatment of Patients with Hemophilia A in Canada
Adapa, Sri, Ovcinnikova, Olga, Leighton, Ian, de Silva, Shamika, Bending, Matthew, Belyanskaya, Larisa, Lidia, Cosentino, Myerson, Anne
Published in Blood (08.12.2017)
Published in Blood (08.12.2017)
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The phosphorylation of stathmin by MAP kinase
Leighton, I A, Curmi, P, Campbell, D G, Cohen, P, Sobel, A
Published in Molecular and cellular biochemistry (01.11.1993)
Published in Molecular and cellular biochemistry (01.11.1993)
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Identification of novel phosphorylation sites required for activation of MAPKAP kinase‐2
Ben‐Levy, R., Leighton, I. A., Doza, Y. N., Attwood, P., Morrice, N., Marshall, C. J., Cohen, P.
Published in The EMBO journal (01.12.1995)
Published in The EMBO journal (01.12.1995)
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